Author results

4JFH
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HIGH AFFINITY ALPHA24-BETA17 T CELL RECEPTOR FOR A2 HLA-MELANOMA PEPTIDE COMPLEX
Descriptor:alpha24 TCR allele, beta17 TCR allele, 1,2-ETHANEDIOL, ...
Authors:Rizkallah, P.J., Cole, D.K., Madura, F., Sewell, A.K.
Deposit date:2013-02-28
Release date:2013-05-29
Last modified:2013-07-17
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:T-cell receptor specificity maintained by altered thermodynamics.
J.Biol.Chem., 288, 2013
4JFO
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A2 HLA COMPLEX WITH E1A HETEROCLITIC VARIANT OF MELANOMA PEPTIDE
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Cole, D.K., Madura, F., Sewell, A.K., Baker, B.M.
Deposit date:2013-02-28
Release date:2013-05-29
Last modified:2013-07-17
Method:X-RAY DIFFRACTION (2.11 Å)
Cite:T-cell receptor specificity maintained by altered thermodynamics.
J.Biol.Chem., 288, 2013
4JFP
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A2 HLA COMPLEX WITH G4A HETEROCLITIC VARIANT OF MELANOMA PEPTIDE
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Cole, D.K., Madura, F., Sewell, A.K.
Deposit date:2013-02-28
Release date:2013-05-29
Last modified:2013-07-17
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:T-cell receptor specificity maintained by altered thermodynamics.
J.Biol.Chem., 288, 2013
4JFQ
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A2 HLA COMPLEX WITH L8A HETEROCLITIC VARIANT OF MELANOMA PEPTIDE
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Cole, D.K., Madura, F., Sewell, A.K., Baker, B.M.
Deposit date:2013-02-28
Release date:2013-05-29
Last modified:2013-07-17
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:T-cell receptor specificity maintained by altered thermodynamics.
J.Biol.Chem., 288, 2013
4MJI
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T CELL RESPONSE TO A HIV REVERSE TRANSCRIPTASE EPITOPE PRESENTED BY THE PROTECTIVE ALLELE HLA-B*51:01
Descriptor:HLA class I histocompatibility antigen, B-51 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Cole, D.K., Sewell, A.K., Motozono, C., Takiguchi, M.
Deposit date:2013-09-03
Release date:2014-05-28
Method:X-RAY DIFFRACTION (2.99 Å)
Cite:Molecular basis of a dominant T cell response to an HIV reverse transcriptase 8-mer epitope presented by the protective allele HLA-B*51:01
J.Immunol., 192, 2014
4MNQ
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TCR-PEPTIDE SPECIFICITY OVERRIDES AFFINITY ENHANCING TCR-MHC INTERACTIONS
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Cole, D.K., Sewell, A.K., Jakobsen, B.K.
Deposit date:2013-09-11
Release date:2013-11-13
Last modified:2017-08-02
Method:X-RAY DIFFRACTION (2.742 Å)
Cite:T-cell receptor (TCR)-peptide specificity overrides affinity-enhancing TCR-major histocompatibility complex interactions.
J.Biol.Chem., 289, 2014
4PHK
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THE STRUCTURAL BASIS OF DIFFERENTIAL INHIBITION OF HUMAN CALPAIN BY INDOLE AND PHENYL ALPHA-MERCAPTOACRYLIC ACIDS. THE COMPLEX WITH (Z)-3-(4-CHLOROPHENYL)-2-MERCAPTOACRYLIC ACID
Descriptor:Calpain small subunit 1, (Z)-3-(4-chlorophenyl)-2-mercaptoacrylic acid, CALCIUM ION
Authors:Rizkallah, P.J., Allemann, R.K., Adams, S.E., Miller, D.J., Hallett, M.B., Robinson, E.
Deposit date:2014-05-06
Release date:2014-08-13
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:The structural basis of differential inhibition of human calpain by indole and phenyl alpha-mercaptoacrylic acids.
J.Struct.Biol., 187, 2014
4PHM
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THE STRUCTURAL BASIS OF DIFFERENTIAL INHIBITION OF HUMAN CALPAIN BY INDOLE AND PHENYL ALPHA-MERCAPTOACRYLIC ACIDS
Descriptor:Calpain small subunit 1, 3-(5-bromo-1H-indol-3-yl)-2-thioxopropanoic acid, CALCIUM ION
Authors:Rizkallah, P.J., Allemann, R.K., Adams, S.E., Miller, D.J., Hallett, M.B.
Deposit date:2014-05-06
Release date:2014-08-13
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:The structural basis of differential inhibition of human calpain by indole and phenyl alpha-mercaptoacrylic acids.
J.Struct.Biol., 187, 2014
4QOK
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STRUCTURAL BASIS FOR INEFFECTIVE T-CELL RESPONSES TO MHC ANCHOR RESIDUE IMPROVED HETEROCLITIC PEPTIDES
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Cole, D.K., Madura, F., Sewell, A.K.
Deposit date:2014-06-20
Release date:2014-12-17
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural basis for ineffective T-cell responses to MHC anchor residue-improved "heteroclitic" peptides.
Eur.J.Immunol., 45, 2015
4U1H
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HLA CLASS I MICROPOLYMORPHISMS DETERMINE PEPTIDE-HLA LANDSCAPE AND DICTATE DIFFERENTIAL HIV-1 ESCAPE THROUGH IDENTICAL EPITOPES
Descriptor:HLA class I histocompatibility antigen, B-7 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Cole, D.K., Fuller, A., Sewell, A.K.
Deposit date:2014-07-15
Release date:2015-04-08
Last modified:2017-08-30
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:A molecular switch in immunodominant HIV-1-specific CD8 T-cell epitopes shapes differential HLA-restricted escape.
Retrovirology, 12, 2015
4U1I
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HLA CLASS I MICROPOLYMORPHISMS DETERMINE PEPTIDE-HLA LANDSCAPE AND DICTATE DIFFERENTIAL HIV-1 ESCAPE THROUGH IDENTICAL EPITOPES
Descriptor:HLA class I histocompatibility antigen, B-81 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Cole, D.K., Fuller, A., Sewell, A.K.
Deposit date:2014-07-15
Release date:2015-04-08
Last modified:2017-08-30
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:A molecular switch in immunodominant HIV-1-specific CD8 T-cell epitopes shapes differential HLA-restricted escape.
Retrovirology, 12, 2015
4U1J
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HLA CLASS I MICROPOLYMORPHISMS DETERMINE PEPTIDE-HLA LANDSCAPE AND DICTATE DIFFERENTIAL HIV-1 ESCAPE THROUGH IDENTICAL EPITOPES
Descriptor:HLA class I histocompatibility antigen, B-42 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Cole, D.K., Fuller, A., Sewell, A.K.
Deposit date:2014-07-15
Release date:2015-04-08
Last modified:2017-08-30
Method:X-RAY DIFFRACTION (1.38 Å)
Cite:A molecular switch in immunodominant HIV-1-specific CD8 T-cell epitopes shapes differential HLA-restricted escape.
Retrovirology, 12, 2015
4U1K
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HLA CLASS I MICROPOLYMORPHISMS DETERMINE PEPTIDE-HLA LANDSCAPE AND DICTATE DIFFERENTIAL HIV-1 ESCAPE THROUGH IDENTICAL EPITOPES
Descriptor:HLA class I histocompatibility antigen, B-7 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Cole, D.K., Fuller, A., Sewell, A.K.
Deposit date:2014-07-15
Release date:2015-04-08
Last modified:2017-08-30
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:A molecular switch in immunodominant HIV-1-specific CD8 T-cell epitopes shapes differential HLA-restricted escape.
Retrovirology, 12, 2015
4U1L
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HLA CLASS I MICROPOLYMORPHISMS DETERMINE PEPTIDE-HLA LANDSCAPE AND DICTATE DIFFERENTIAL HIV-1 ESCAPE THROUGH IDENTICAL EPITOPES
Descriptor:HLA class I histocompatibility antigen, B-81 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Cole, D.K., Fuller, A., Sewell, A.K.
Deposit date:2014-07-15
Release date:2015-04-08
Last modified:2017-08-30
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:A molecular switch in immunodominant HIV-1-specific CD8 T-cell epitopes shapes differential HLA-restricted escape.
Retrovirology, 12, 2015
4U1M
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HLA CLASS I MICROPOLYMORPHISMS DETERMINE PEPTIDE-HLA LANDSCAPE AND DICTATE DIFFERENTIAL HIV-1 ESCAPE THROUGH IDENTICAL EPITOPES
Descriptor:HLA class I histocompatibility antigen, B-42 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Cole, D.K., Fuller, A., Sewell, A.K.
Deposit date:2014-07-15
Release date:2015-04-08
Last modified:2017-08-30
Method:X-RAY DIFFRACTION (1.18 Å)
Cite:A molecular switch in immunodominant HIV-1-specific CD8 T-cell epitopes shapes differential HLA-restricted escape.
Retrovirology, 12, 2015
4U1N
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HLA CLASS I MICROPOLYMORPHISMS DETERMINE PEPTIDE-HLA LANDSCAPE AND DICTATE DIFFERENTIAL HIV-1 ESCAPE THROUGH IDENTICAL EPITOPES
Descriptor:HLA class I histocompatibility antigen, B-42 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Cole, D.K., Fuller, A., Sewell, A.K.
Deposit date:2014-07-15
Release date:2015-04-08
Last modified:2017-08-30
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:A molecular switch in immunodominant HIV-1-specific CD8 T-cell epitopes shapes differential HLA-restricted escape.
Retrovirology, 12, 2015
4U1S
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HLA CLASS I MICROPOLYMORPHISMS DETERMINE PEPTIDE-HLA LANDSCAPE AND DICTATE DIFFERENTIAL HIV-1 ESCAPE THROUGH IDENTICAL EPITOPES
Descriptor:HLA class I histocompatibility antigen, B-81 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Cole, D.K., Fuller, A., Sewell, A.K.
Deposit date:2014-07-16
Release date:2015-04-08
Last modified:2017-08-30
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:A molecular switch in immunodominant HIV-1-specific CD8 T-cell epitopes shapes differential HLA-restricted escape.
Retrovirology, 12, 2015
4WDI
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WEAK TCR BINDING TO AN UNSTABLE INSULIN EPITOPE DRIVES TYPE 1 DIABETES
Descriptor:H-2 class I histocompatibility antigen, K-D alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Cole, D.K.
Deposit date:2014-09-08
Release date:2015-06-24
Last modified:2015-07-01
Method:X-RAY DIFFRACTION (2.313 Å)
Cite:Distortion of the Major Histocompatibility Complex Class I Binding Groove to Accommodate an Insulin-derived 10-Mer Peptide.
J.Biol.Chem., 290, 2015
4Z76
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WEAK TCR BINDING TO AN UNSTABLE INSULIN EPITOPE DRIVES TYPE 1 DIABETES
Descriptor:H-2 class I histocompatibility antigen, K-D alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Cole, D.K.
Deposit date:2015-04-06
Release date:2015-06-24
Last modified:2015-08-12
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Distortion of the Major Histocompatibility Complex Class I Binding Groove to Accommodate an Insulin-derived 10-Mer Peptide.
J.Biol.Chem., 290, 2015
4Z78
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WEAK TCR BINDING TO AN UNSTABLE INSULIN EPITOPE DRIVES TYPE 1 DIABETES
Descriptor:H-2 class I histocompatibility antigen, K-D alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Cole, D.K.
Deposit date:2015-04-06
Release date:2015-06-24
Last modified:2015-08-12
Method:X-RAY DIFFRACTION (2.304 Å)
Cite:Distortion of the Major Histocompatibility Complex Class I Binding Groove to Accommodate an Insulin-derived 10-Mer Peptide.
J.Biol.Chem., 290, 2015
5C07
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1E6 TCR IN COMPLEX WITH HLA-A02 CARRYING YQFGPDFPIA
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Bulek, A.M., Cole, D.K., Sewell, A.K.
Deposit date:2015-06-12
Release date:2016-05-04
Last modified:2016-06-08
Method:X-RAY DIFFRACTION (2.11 Å)
Cite:Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity.
J.Clin.Invest., 126, 2016
5C08
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1E6 TCR IN COMPLEX WITH HLA-A0E CARRYING RQWGPDPAAV
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Bulek, A.M., Cole, D.K., Sewell, A.K.
Deposit date:2015-06-12
Release date:2016-05-04
Last modified:2016-06-08
Method:X-RAY DIFFRACTION (2.332 Å)
Cite:Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity.
J.Clin.Invest., 126, 2016
5C09
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HLA CLASS I HISTOCOMPATIBILITY ANTIGEN
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Bulek, A.M., Cole, D.K., Sewell, A.K.
Deposit date:2015-06-12
Release date:2016-05-04
Last modified:2016-06-08
Method:X-RAY DIFFRACTION (2.475 Å)
Cite:Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity.
J.Clin.Invest., 126, 2016
5C0A
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1E6 TCR IN COMPLEX WITH HLA-A02 CARRYING MVW PEPTIDE
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Bulek, A.M., Cole, D.K., Sewell, A.K.
Deposit date:2015-06-12
Release date:2016-05-04
Last modified:2016-06-08
Method:X-RAY DIFFRACTION (2.46 Å)
Cite:Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity.
J.Clin.Invest., 126, 2016
5C0B
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1E6 TCR IN COMPLEX WITH HLA-A02 CARRYING RQFGPDFPTI
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Rizkallah, P.J., Bulek, A.M., Cole, D.K., Sewell, A.K.
Deposit date:2015-06-12
Release date:2016-05-04
Last modified:2016-06-08
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity.
J.Clin.Invest., 126, 2016