Author results

2RFI
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CRYSTAL STRUCTURE OF CATALYTIC DOMAIN OF HUMAN EUCHROMATIC HISTONE METHYLTRANSFERASE 1 IN COMPLEX WITH SAH AND DIMETHYLATED H3K9 PEPTIDE
分子名称:Histone-lysine N-methyltransferase, H3 lysine-9 specific 5, Histone H3, ...
著者Min, J., Wu, H., Loppnau, P., Weigelt, J., Sundstrom, M., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Plotnikov, A.N., Structural Genomics Consortium (SGC)
登録日2007-09-30
公開日2007-10-23
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.59 Å)
主引用文献Structural biology of human H3K9 methyltransferases
Plos One, 5, 2010
3C0Z
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CRYSTAL STRUCTURE OF CATALYTIC DOMAIN OF HUMAN HISTONE DEACETYLASE HDAC7 IN COMPLEX WITH SAHA
分子名称:Histone deacetylase 7a, ZINC ION, POTASSIUM ION, ...
著者Min, J., Schuetz, A., Loppnau, P., Weigelt, J., Sundstrom, M., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Plotnikov, A.N., Structural Genomics Consortium (SGC)
登録日2008-01-21
公開日2008-02-19
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Human HDAC7 harbors a class IIa histone deacetylase-specific zinc binding motif and cryptic deacetylase activity.
J.Biol.Chem., 283, 2008
3C10
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CRYSTAL STRUCTURE OF CATALYTIC DOMAIN OF HUMAN HISTONE DEACETYLASE HDAC7 IN COMPLEX WITH TRICHOSTATIN A (TSA)
分子名称:Histone deacetylase 7a, ZINC ION, POTASSIUM ION, ...
著者Min, J., Schuetz, A., Loppnau, P., Weigelt, J., Sundstrom, M., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Plotnikov, A.N., Structural Genomics Consortium (SGC)
登録日2008-01-21
公開日2008-02-19
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Human HDAC7 harbors a class IIa histone deacetylase-specific zinc binding motif and cryptic deacetylase activity.
J.Biol.Chem., 283, 2008
3C6K
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CRYSTAL STRUCTURE OF HUMAN SPERMINE SYNTHASE IN COMPLEX WITH SPERMIDINE AND 5-METHYLTHIOADENOSINE
分子名称:Spermine synthase, SPERMIDINE, 5'-DEOXY-5'-METHYLTHIOADENOSINE
著者Min, J., Wu, H., Zeng, H., Loppnau, P., Weigelt, J., Sundstrom, M., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Pegg, A.E., Plotnikov, A.N., Structural Genomics Consortium (SGC)
登録日2008-02-04
公開日2008-02-19
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Crystal structure of human spermine synthase: implications of substrate binding and catalytic mechanism.
J.Biol.Chem., 283, 2008
3C6M
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CRYSTAL STRUCTURE OF HUMAN SPERMINE SYNTHASE IN COMPLEX WITH SPERMINE AND 5-METHYLTHIOADENOSINE
分子名称:Spermine synthase, SPERMINE, 5'-DEOXY-5'-METHYLTHIOADENOSINE
著者Min, J., Wu, H., Zeng, H., Loppnau, P., Weigelt, J., Sundstrom, M., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Pegg, A.E., Plotnikov, A.N., Structural Genomics Consortium (SGC)
登録日2008-02-04
公開日2008-02-19
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Crystal structure of human spermine synthase: implications of substrate binding and catalytic mechanism.
J.Biol.Chem., 283, 2008
3HNA
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CRYSTAL STRUCTURE OF CATALYTIC DOMAIN OF HUMAN EUCHROMATIC HISTONE METHYLTRANSFERASE 1 IN COMPLEX WITH SAH AND MONO-METHYLATED H3K9 PEPTIDE
分子名称:Histone-lysine N-methyltransferase, H3 lysine-9 specific 5, Mono-Methylated H3K9 Peptide, ...
著者Min, J., Wu, H., Loppnau, P., Wleigelt, J., Sundstrom, M., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Plotnikov, A.N., Structural Genomics Consortium (SGC)
登録日2009-05-30
公開日2009-06-09
最終更新日2014-12-17
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural biology of human H3K9 methyltransferases
Plos One, 5, 2010
5UC1
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STRUCTURAL ANALYSIS OF GLUCOCORTICOID RECEPTOR BETA LIGAND BINDING DOMAIN COMPLEXED WITH GLUCOCORTICOID ANTAGONIST RU-486: IMPLICATION OF HELIX 12 IN ANTAGONISM
分子名称:Glucocorticoid receptor, 11-(4-DIMETHYLAMINO-PHENYL)-17-HYDROXY-13-METHYL-17-PROP-1-YNYL-1,2,6,7,8,11,12,13,14,15,16,17-DODEC AHYDRO-CYCLOPENTA[A]PHENANTHREN-3-ONE, 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, ...
著者Pedersen, L.C., Min, J.
登録日2016-12-21
公開日2017-12-27
最終更新日2018-06-20
実験手法X-RAY DIFFRACTION (2.351 Å)
主引用文献Probing Dominant Negative Behavior of Glucocorticoid Receptor beta through a Hybrid Structural and Biochemical Approach.
Mol. Cell. Biol., 2018
4ZN9
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CRYSTAL STRUCTURE OF THE ER-ALPHA LIGAND-BINDING DOMAIN (Y537S) IN COMPLEX WITH OXABICYCLIC HEPTENE SULFONATE (OBHS)
分子名称:Estrogen receptor, Nuclear receptor-interacting peptide, cyclohexa-2,5-dien-1-yl (1S,2R,4S)-5,6-bis(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonate
著者Nwachukwu, J.C., Srinivasan, S., Zheng, Y., Wang, S., Min, J., Dong, C., Liao, Z., Cavett, V., Nowak, J., Houtman, R., Carlson, K.E., Josan, J.S., Elemento, O., Katzenellenbogen, J.A., Zhou, H.B., Nettles, K.W.
登録日2015-05-04
公開日2015-09-09
実験手法X-RAY DIFFRACTION (2.215 Å)
主引用文献Development of selective estrogen receptor modulator (SERM)-like activity through an indirect mechanism of estrogen receptor antagonism: defining the binding mode of 7-oxabicyclo[2.2.1]hept-5-ene scaffold core ligands.
Chemmedchem, 7, 2012
3DM1
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CRYSTAL STRUCTURE OF THE COMPLEX OF HUMAN CHROMOBOX HOMOLOG 3 (CBX3) WITH PEPTIDE
分子名称:Chromobox protein homolog 3, Histone-lysine N-methyltransferase, H3 lysine-9 specific 3
著者Amaya, M.F., Ravichandran, M., Loppnau, P., Kozieradzki, I., Edwards, A.M., Arrowsmith, C.H., Weigelt, J., Bountra, C., Bochkarev, A., Min, J., Ouyang, H., Structural Genomics Consortium (SGC)
登録日2008-06-30
公開日2008-08-19
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural basis of the chromodomain of Cbx3 bound to methylated peptides from histone h1 and G9a.
Plos One, 7, 2012
3FEO
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THE CRYSTAL STRUCTURE OF MBTD1
分子名称:MBT domain-containing protein 1
著者Amaya, M.F., Eryilmaz, J., Kozieradzki, I., Edwards, A.M., Arrowsmith, C.H., Weigelt, J., Bountra, C., Bochkarev, A., Min, J., Structural Genomics Consortium (SGC)
登録日2008-11-30
公開日2009-01-06
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural studies of a four-MBT repeat protein MBTD1.
Plos One, 4, 2009
3LWE
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THE CRYSTAL STRUCTURE OF MPP8
分子名称:M-phase phosphoprotein 8
著者Li, Z., Li, Z., Ruan, J., Xu, C., Tong, Y., Pan, P.W., Tempel, W., Crombet, L., Min, J., Zang, J., Structural Genomics Consortium (SGC)
登録日2010-02-23
公開日2010-03-02
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Structural basis for specific binding of human MPP8 chromodomain to histone H3 methylated at lysine 9.
Plos One, 6, 2011
3LX7
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CRYSTAL STRUCTURE OF A NOVEL TUDOR DOMAIN-CONTAINING PROTEIN SGF29
分子名称:SAGA-associated factor 29 homolog, SULFATE ION, UNKNOWN ATOM OR ION
著者Bian, C.B., Xu, C., Tempel, W., Lam, R., Bountra, C., Arrowsmith, C.H., Weigelt, J., Edwards, A.M., Bochkarev, A., Min, J.
登録日2010-02-24
公開日2010-05-05
最終更新日2011-08-03
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation.
Embo J., 30, 2011
3ME9
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CRYSTAL STRUCTURE OF SGF29 IN COMPLEX WITH H3K4ME3 PEPTIDE
分子名称:SAGA-associated factor 29 homolog, Histone H3, UNKNOWN ATOM OR ION, ...
著者Bian, C., Tempel, W., Xu, C., Guo, Y., Dong, A., Crombet, L., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Min, J., Structural Genomics Consortium (SGC)
登録日2010-03-31
公開日2010-04-28
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (1.37 Å)
主引用文献Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation.
Embo J., 30, 2011
3MEA
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CRYSTAL STRUCTURE OF THE SGF29 IN COMPLEX WITH H3K4ME3
分子名称:SAGA-associated factor 29 homolog, Histone H3
著者Bian, C., Xu, C., Tempel, W., MacKenzie, F., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Min, J., Structural Genomics Consortium (SGC)
登録日2010-03-31
公開日2010-04-28
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (1.26 Å)
主引用文献Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation.
Embo J., 30, 2011
3MET
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CRYSTAL STRUCTURE OF SGF29 IN COMPLEX WITH H3K4ME2
分子名称:SAGA-associated factor 29 homolog, Histone H3, UNKNOWN ATOM OR ION, ...
著者Bian, C.B., Xu, C., Lam, R., Bountra, C., Arrowsmith, C.H., Weigelt, J., Edwards, A.M., Bochkarev, A., Min, J., Structural Genomics Consortium (SGC)
登録日2010-03-31
公開日2010-04-28
最終更新日2011-08-03
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation.
Embo J., 30, 2011
3MEU
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CRYSTAL STRUCTURE OF SGF29 IN COMPLEX WITH H3R2ME2SK4ME3
分子名称:SAGA-associated factor 29 homolog, Histone H3, SULFATE ION
著者Bian, C.B., Xu, C., Bountra, C., Arrowsmith, C.H., Weigelt, J., Edwards, A.M., Bochkarev, A., Min, J., Structural Genomics Consortium (SGC)
登録日2010-03-31
公開日2010-04-28
最終更新日2011-08-03
実験手法X-RAY DIFFRACTION (1.28 Å)
主引用文献Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation.
Embo J., 30, 2011
3MEV
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CRYSTAL STRUCTURE OF SGF29 IN COMPLEX WITH R2AK4ME3
分子名称:SAGA-associated factor 29 homolog, Histone H3, SULFATE ION, ...
著者Bian, C.B., Xu, C., Lam, R., Bountra, C., Arrowsmith, C.H., Weigelt, J., Edwards, A.M., Bochkarev, A., Min, J., Structural Genomics Consortium (SGC)
登録日2010-03-31
公開日2010-04-28
最終更新日2012-05-09
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation.
Embo J., 30, 2011
3MEW
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CRYSTAL STRUCTURE OF NOVEL TUDOR DOMAIN-CONTAINING PROTEIN SGF29
分子名称:SAGA-associated factor 29 homolog
著者Xu, C., Bian, C.B., Lam, R., Bountra, C., Arrowsmith, C.H., Weigelt, J., Edwards, A.M., Bochkarev, A., Min, J., Structural Genomics Consortium (SGC)
登録日2010-03-31
公開日2010-04-28
最終更新日2011-08-03
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation.
Embo J., 30, 2011
3MTS
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CHROMO DOMAIN OF HUMAN HISTONE-LYSINE N-METHYLTRANSFERASE SUV39H1
分子名称:Histone-lysine N-methyltransferase SUV39H1
著者Lam, R., Li, Z., Wang, J., Crombet, L., Walker, J.R., Ouyang, H., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Min, J., Structural Genomics Consortium (SGC)
登録日2010-04-30
公開日2010-06-30
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal Structure of the Human SUV39H1 Chromodomain and Its Recognition of Histone H3K9me2/3.
Plos One, 7, 2012
3QIR
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CRYSTAL STRUCTURE OF PIWIL2 PAZ DOMAIN
分子名称:Piwi-like protein 2
著者Dong, A., Xu, C., Bian, C., Wernimont, A.K., Kania, J., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Min, J., Structural Genomics Consortium (SGC)
登録日2011-01-27
公開日2011-02-16
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Crystal structure of PIWIL2 PAZ domain
To be Published
3R93
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CRYSTAL STRUCTURE OF THE CHROMO DOMAIN OF M-PHASE PHOSPHOPROTEIN 8 BOUND TO H3K9ME3 PEPTIDE
分子名称:M-phase phosphoprotein 8, H3K9Me3 peptide, UNKNOWN ATOM OR ION
著者Li, J., Li, Z., Ruan, J., Xu, C., Tong, Y., Pan, P.W., Tempel, W., Crombet, L., Min, J., Zang, J., Structural Genomics Consortium (SGC)
登録日2011-03-24
公開日2011-04-06
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2.057 Å)
主引用文献Structural basis for specific binding of human MPP8 chromodomain to histone H3 methylated at lysine 9.
Plos One, 6, 2011
3S93
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CRYSTAL STRUCTURE OF CONSERVED MOTIF IN TDRD5
分子名称:Tudor domain-containing protein 5, UNKNOWN ATOM OR ION
著者Chao, X., Tempel, W., Bian, C., Kania, J., Wernimont, A.K., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Min, J., Structural Genomics Consortium (SGC)
登録日2011-05-31
公開日2011-08-31
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献Crystal structure of conserved motif in TDRD5
to be published
3TYY
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CRYSTAL STRUCTURE OF HUMAN LAMIN-B1 COIL 2 SEGMENT
分子名称:Lamin-B1
著者Lam, R., Xu, C., Bian, C.B., Mackenzie, F., Walker, J.R., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Min, J., Structural Genomics Consortium (SGC)
登録日2011-09-26
公開日2011-10-05
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2.399 Å)
主引用文献Crystal structures of the coil 2B fragment and the globular tail domain of human lamin B1.
Febs Lett., 586, 2012
3TZD
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CRYSTAL STRUCTURE OF THE COMPLEX OF HUMAN CHROMOBOX HOMOLOG 3 (CBX3)
分子名称:Chromobox protein homolog 3, Histone H1.4
著者Amaya, M.F., Ravichandran, M., Loppnau, P., Kozieradzki, I., Edwards, A.M., Arrowsmith, C.H., Weigelt, J., Bountra, C., Bochkarev, A., Min, J., Ouyang, H., Structural Genomics Consortium (SGC)
登録日2011-09-27
公開日2012-03-07
最終更新日2013-01-23
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献Structural basis of the chromodomain of Cbx3 bound to methylated peptides from histone h1 and G9a.
Plos One, 7, 2012
3UMN
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CRYSTAL STRUCTURE OF LAMIN-B1
分子名称:Lamin-B1
著者Xu, C., Bian, C.B., Amaya, M.F., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Min, J., Structural Genomics Consortium (SGC)
登録日2011-11-14
公開日2011-11-30
最終更新日2012-03-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structures of the coil 2B fragment and the globular tail domain of human lamin B1.
Febs Lett., 586, 2012