Author results

5NQI
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E.COLI 16S RRNA SARCIN-RICIN LOOP CONTAINING A 5-HYDROXYMETHYLCYTOSINE MODIFICATION
Descriptor:E.Coli 27-mer SRL RNA
Authors:Ennifar, E., Micura, R.
Deposit date:2017-04-20
Release date:2017-07-26
Last modified:2017-08-16
Method:X-RAY DIFFRACTION (0.851 Å)
Cite:Synthesis, Thermodynamic Properties, and Crystal Structure of RNA Oligonucleotides Containing 5-Hydroxymethylcytosine.
J. Org. Chem., 82, 2017
6N9E
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CRYSTAL STRUCTURE OF THE THERMUS THERMOPHILUS 70S RIBOSOME IN COMPLEX WITH A SHORT SUBSTRATE MIMIC CC-PMN AND BOUND TO MRNA AND P-SITE TRNA AT 3.7A RESOLUTION
Descriptor:23S Ribosomal RNA, 5S Ribosomal RNA, 50S Ribosomal Protein L2, ...
Authors:Melnikov, S.V., Khabibullina, N.F., Mairhofer, E., Vargas-Rodriguez, O., Reynolds, N.M., Micura, R., Soll, D., Polikanov, Y.S.
Deposit date:2018-12-03
Release date:2018-12-12
Last modified:2018-12-19
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Mechanistic insights into the slow peptide bond formation with D-amino acids in the ribosomal active site.
Nucleic Acids Res., 2018
6N9F
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CRYSTAL STRUCTURE OF THE THERMUS THERMOPHILUS 70S RIBOSOME IN COMPLEX WITH A SHORT SUBSTRATE MIMIC ACCA-DPHE AND BOUND TO MRNA AND P-SITE TRNA AT 3.7A RESOLUTION
Descriptor:23S Ribosomal RNA, 5S Ribosomal RNA, 50S Ribosomal Protein L2, ...
Authors:Melnikov, S.V., Khabibullina, N.F., Mairhofer, E., Vargas-Rodriguez, O., Reynolds, N.M., Micura, R., Soll, D., Polikanov, Y.S.
Deposit date:2018-12-03
Release date:2018-12-12
Last modified:2018-12-19
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Mechanistic insights into the slow peptide bond formation with D-amino acids in the ribosomal active site.
Nucleic Acids Res., 2018
2H1M
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SYNTHESIS, OXIDATION BEHAVIOR, CRYSTALLIZATION AND STRUCTURE OF 2'-METHYLSELENO GUANOSINE CONTAINING RNAS
Descriptor:5'-R(*GP*CP*AP*(XUG)P*AP*GP*UP*UP*AP*AP*AP*UP*CP*UP*GP*C)-3', SULFATE ION
Authors:Serganov, A.A.
Deposit date:2006-05-16
Release date:2006-07-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Synthesis, Oxidation Behavior, Crystallization and Structure of 2'-Methylseleno Guanosine Containing RNAs.
J.Am.Chem.Soc., 128, 2006
5Y85
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STRUCTURE-BASED INSIGHTS INTO SELF-CLEAVAGE BY A FOUR-WAY JUNCTIONAL TWISTER-SISTER RIBOZYME
Descriptor:RNA (5'-R(P*AP*CP*CP*CP*GP*CP*AP*AP*GP*GP*CP*CP*GP*AP*CP*GP*GP*C)-3'), DNA/RNA (50-MER), MAGNESIUM ION
Authors:Zheng, L., Micura, R.L., Ren, A.
Deposit date:2017-08-18
Release date:2017-11-22
Method:X-RAY DIFFRACTION (2.001 Å)
Cite:Structure-based insights into self-cleavage by a four-way junctional twister-sister ribozyme
Nat Commun, 8, 2017
5Y87
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STRUCTURE-BASED INSIGHTS INTO SELF-CLEAVAGE BY A FOUR-WAY JUNCTIONAL TWISTER-SISTER RIBOZYME
Descriptor:RNA (5'-R(P*AP*CP*CP*CP*GP*CP*AP*AP*GP*GP*CP*CP*GP*AP*CP*GP*GP*C)-3'), DNA/RNA (50-MER), MANGANESE (II) ION
Authors:Zheng, L., Micura, R.L., Ren, A.
Deposit date:2017-08-19
Release date:2017-11-22
Last modified:2019-01-23
Method:X-RAY DIFFRACTION (2.132 Å)
Cite:Structure-based insights into self-cleavage by a four-way junctional twister-sister ribozyme
Nat Commun, 8, 2017
1Y26
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A-RIBOSWITCH-ADENINE COMPLEX
Descriptor:Vibrio vulnificus A-riboswitch, MAGNESIUM ION, ADENINE
Authors:Serganov, A., Yuan, Y.R., Patel, D.J.
Deposit date:2004-11-20
Release date:2004-12-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Basis for Discriminative Regulation of Gene Expression by Adenine- and Guanine-Sensing mRNAs
Chem.Biol., 11, 2004
1Y27
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G-RIBOSWITCH-GUANINE COMPLEX
Descriptor:Bacillus subtilis xpt, HYPOPHOSPHITE, GUANOSINE-5'-MONOPHOSPHATE
Authors:Serganov, A., Yuan, Y.R., Patel, D.J.
Deposit date:2004-11-20
Release date:2004-12-28
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural Basis for Discriminative Regulation of Gene Expression by Adenine- and Guanine-Sensing mRNAs
Chem.Biol., 11, 2004
2Q1O
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CRYSTAL STRUCTURE ANALYSIS OF THE RNA DODECAMER CGC-NF2-AAUUGGCG, WITH AN INCORPORATED 2,4-DIFLUOROTOLUYL RESIDUE (NF2)
Descriptor:RNA (5'-R(*CP*GP*CP*(NF2)P*AP*AP*UP*UP*GP*GP*CP*G)-3')
Authors:Li, F., Pallan, P.S.
Deposit date:2007-05-25
Release date:2007-10-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Crystal structure, stability and in vitro RNAi activity of oligoribonucleotides containing the ribo-difluorotoluyl nucleotide: insights into substrate requirements by the human RISC Ago2 enzyme.
Nucleic Acids Res., 35, 2007
2Q1R
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CRYSTAL STRUCTURE ANALYSIS OF THE RNA DODECAMER CGCGAAUUAGCG, WITH A G-A MISMATCH.
Descriptor:RNA (5'-R(*CP*GP*CP*GP*AP*AP*UP*UP*AP*GP*CP*G)-3'), MAGNESIUM ION
Authors:Li, F., Pallan, P.S.
Deposit date:2007-05-25
Release date:2007-10-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.12 Å)
Cite:Crystal structure, stability and in vitro RNAi activity of oligoribonucleotides containing the ribo-difluorotoluyl nucleotide: insights into substrate requirements by the human RISC Ago2 enzyme.
Nucleic Acids Res., 35, 2007
2QEK
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HIV-1 SUBTYPE F DIS RNA EXTENDED DUPLEX FORM
Descriptor:HIV-1 subtype F DIS genomic RNA, POTASSIUM ION, MAGNESIUM ION
Authors:Freisz, S., Ennifar, E., Dumas, P.
Deposit date:2007-06-26
Release date:2008-05-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Binding of aminoglycoside antibiotics to the duplex form of the HIV-1 genomic RNA dimerization initiation site.
Angew.Chem.Int.Ed.Engl., 47, 2008
3C44
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CRYSTAL STRUCTURE OF HIV-1 SUBTYPE F DIS EXTENDED DUPLEX RNA BOUND TO PAROMOMYCIN
Descriptor:HIV-1 subtype F genomic RNA, PAROMOMYCIN, POTASSIUM ION, ...
Authors:Freisz, S., Ennifar, E., Dumas, P.
Deposit date:2008-01-29
Release date:2008-05-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Binding of aminoglycoside antibiotics to the duplex form of the HIV-1 genomic RNA dimerization initiation site.
Angew.Chem.Int.Ed.Engl., 47, 2008
3DVV
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CRYSTAL STRUCTURE OF HIV-1 SUBTYPE F DIS EXTENDED DUPLEX RNA BOUND TO RIBOSTAMYCIN (U267OME)
Descriptor:HIV-1 genomic RNA, POTASSIUM ION, CHLORIDE ION, ...
Authors:Ennifar, E., Dumas, P., Olieric, V.
Deposit date:2008-07-21
Release date:2008-08-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:A fast strategy for Selenium derivatization and phasing of RNA structures
To be Published
3NCU
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STRUCTURAL AND FUNCTIONAL INSIGHTS INTO PATTERN RECOGNITION BY THE INNATE IMMUNE RECEPTOR RIG-I
Descriptor:RIG-I, 5'-R(*(GDP)P*AP*CP*GP*CP*UP*AP*GP*CP*GP*UP*C)-3', ZINC ION
Authors:Sheng, G., Li, H.
Deposit date:2010-06-05
Release date:2010-06-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structural and functional insights into 5'-ppp RNA pattern recognition by the innate immune receptor RIG-I.
Nat.Struct.Mol.Biol., 17, 2010
4RGE
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CRYSTAL STRUCTURE OF THE IN-LINE ALIGNED ENV22 TWISTER RIBOZYME
Descriptor:env22 twister ribozyme, MAGNESIUM ION
Authors:Ren, A., Rajashankar, K.R., Simanshu, D., Patel, D.
Deposit date:2014-09-30
Release date:2014-12-03
Method:X-RAY DIFFRACTION (2.89 Å)
Cite:In-line alignment and Mg(2+) coordination at the cleavage site of the env22 twister ribozyme.
Nat Commun, 5, 2014
4RGF
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CRYSTAL STRUCTURE OF THE IN-LINE ALIGNED ENV22 TWISTER RIBOZYME SOAKED WITH MN2+
Descriptor:env22 twister ribozyme, MANGANESE (II) ION, POTASSIUM ION, ...
Authors:Ren, A., Rajashankar, K.R., Simanshu, D., Patel, D.
Deposit date:2014-09-30
Release date:2014-12-03
Method:X-RAY DIFFRACTION (3.2008 Å)
Cite:In-line alignment and Mg(2+) coordination at the cleavage site of the env22 twister ribozyme.
Nat Commun, 5, 2014
5K7C
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THE NATIVE STRUCTURE OF NATIVE PISTOL RIBOZYME
Descriptor:RNA 47-MER, DNA/RNA 11-MER, MAGNESIUM ION
Authors:Ren, A., Patel, D.
Deposit date:2016-05-26
Release date:2016-07-13
Last modified:2016-08-31
Method:X-RAY DIFFRACTION (2.73 Å)
Cite:Pistol ribozyme adopts a pseudoknot fold facilitating site-specific in-line cleavage.
Nat.Chem.Biol., 12, 2016
5K7D
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THE STRUCTURE OF NATIVE PISTOL RIBOZYME, BOUND TO IRIDIUM
Descriptor:RNA 47-MER, DNA/RNA 11-MER, IRIDIUM HEXAMMINE ION, ...
Authors:Ren, A., Patel, D.
Deposit date:2016-05-26
Release date:2016-07-13
Last modified:2016-08-31
Method:X-RAY DIFFRACTION (2.68 Å)
Cite:Pistol ribozyme adopts a pseudoknot fold facilitating site-specific in-line cleavage.
Nat.Chem.Biol., 12, 2016
5K7E
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THE STRUCTURE OF PISTOL RIBOZYME, SOAKED WITH MN2+
Descriptor:RNA 47-MER, DNA/RNA 11-MER, MANGANESE (II) ION
Authors:Ren, A., Patel, D.
Deposit date:2016-05-26
Release date:2016-07-13
Last modified:2016-08-31
Method:X-RAY DIFFRACTION (3.27 Å)
Cite:Pistol ribozyme adopts a pseudoknot fold facilitating site-specific in-line cleavage.
Nat.Chem.Biol., 12, 2016
5LYB
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CRYSTAL STRUCTURE OF THE S.CEREVISIAE 80S RIBOSOME IN COMPLEX WITH THE A-SITE BOUND AMINOACYL-TRNA ANALOG ACCPMN
Descriptor:18S rRNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ...
Authors:Melnikov, S., Mailliot, J.
Deposit date:2016-09-26
Release date:2016-11-23
Last modified:2016-12-14
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Molecular insights into protein synthesis with proline residues.
EMBO Rep., 17, 2016
5TGA
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CRYSTAL STRUCTURE OF THE S.CEREVISIAE 80S RIBOSOME IN COMPLEX WITH THE A-SITE BOUND AMINOACYL-TRNA ANALOG ACCA-PRO
Descriptor:18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ...
Authors:Melnikov, S., Mailliot, J.
Deposit date:2016-09-27
Release date:2016-11-23
Last modified:2016-12-14
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Molecular insights into protein synthesis with proline residues.
EMBO Rep., 17, 2016
5TGM
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CRYSTAL STRUCTURE OF THE S.CEREVISIAE 80S RIBOSOME IN COMPLEX WITH THE A-SITE BOUND AMINOACYL-TRNA ANALOG ACCA-PRO
Descriptor:18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ...
Authors:Melnikov, S., Mailliot, J., Yusupov, M.
Deposit date:2016-09-28
Release date:2017-01-18
Last modified:2017-01-25
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Molecular insights into protein synthesis with proline residues.
EMBO Rep., 17, 2016
5VXB
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CRYSTAL STRUCTURE OF CAULOBACTER CRESCENTUS PROXP-ALA AT 1.69 ANGSTROM
Descriptor:ProXp-ala
Authors:Foster, M.P., Musier-Forsyth, K., Nakanishi, K., Ma, X.
Deposit date:2017-05-23
Release date:2017-08-09
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Conformational and chemical selection by a trans-acting editing domain.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5D99
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3DW4 REDETERMINED BY DIRECT METHODS STARTING FROM RANDOM PHASE ANGLES
Descriptor:RNA (27-MER) hairpin from sarcin-ricin domain of E. coli 23S rRNA, GLYCEROL
Authors:Mooers, B.H.M.
Deposit date:2015-08-18
Release date:2016-04-13
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (0.97 Å)
Cite:Direct-methods structure determination of a trypanosome RNA-editing substrate fragment with translational pseudosymmetry
Acta Crystallogr.,Sect.D, 72, 2016
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