Author results

3EYJ
  • Download 3eyj
  • View 3eyj
Molmil generated image of 3eyj
STRUCTURE OF INFLUENZA HAEMAGGLUTININ IN COMPLEX WITH AN INHIBITOR OF MEMBRANE FUSION
Descriptor:Hemagglutinin HA1 chain, Hemagglutinin HA2 chain
Authors:Russell, R.J., Kerry, P.S., Stevens, D.J., Steinahuer, D.A., Martin, S.R., Gamblin, S.J., Skehel, J.J.
Deposit date:2008-10-21
Release date:2009-01-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of influenza hemagglutinin in complex with an inhibitor of membrane fusion
Proc.Natl.Acad.Sci.USA, 105, 2008
3EYK
  • Download 3eyk
  • View 3eyk
Molmil generated image of 3eyk
STRUCTURE OF INFLUENZA HAEMAGGLUTININ IN COMPLEX WITH AN INHIBITOR OF MEMBRANE FUSION
Descriptor:Hemagglutinin HA1 chain, Hemagglutinin HA2 chain, 2-tert-butylbenzene-1,4-diol
Authors:Russell, R.J., Kerry, P.S., Stevens, D.J., Steinhauer, D.A., Martin, S.R., Gamblin, S.J., Skehel, J.J.
Deposit date:2008-10-21
Release date:2009-01-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of influenza hemagglutinin in complex with an inhibitor of membrane fusion
Proc.Natl.Acad.Sci.USA, 105, 2008
3EYM
  • Download 3eym
  • View 3eym
Molmil generated image of 3eym
STRUCTURE OF INFLUENZA HAEMAGGLUTININ IN COMPLEX WITH AN INHIBITOR OF MEMBRANE FUSION
Descriptor:Hemagglutinin HA1 chain, Hemagglutinin HA2 chain, 2-tert-butylbenzene-1,4-diol
Authors:Russell, R.J., Kerry, P.S., Stevens, D.A., Steinhauer, D.A., Martin, S.R., Gamblin, S.J., Skehel, J.J.
Deposit date:2008-10-21
Release date:2009-01-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of influenza hemagglutinin in complex with an inhibitor of membrane fusion
Proc.Natl.Acad.Sci.USA, 105, 2008
3T4N
  • Download 3t4n
  • View 3t4n
Molmil generated image of 3t4n
STRUCTURE OF THE REGULATORY FRAGMENT OF SACCHAROMYCES CEREVISIAE AMPK IN COMPLEX WITH ADP
Descriptor:Carbon catabolite-derepressing protein kinase, SNF1 protein kinase subunit beta-2, Nuclear protein SNF4, ...
Authors:Mayer, F.V., Heath, R., Underwood, E., Sanders, M.J., Carmena, D., McCartney, R., Leiper, F.C., Xiao, B., Jing, C., Walker, P.A., Haire, L.F., Ogrodowicz, R., Martin, S.R., Schmdit, M.C., Gamblin, S.J., Carling, D.
Deposit date:2011-07-26
Release date:2011-11-09
Last modified:2011-11-23
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:ADP Regulates SNF1, the Saccharomyces cerevisiae Homolog of AMP-Activated Protein Kinase.
Cell Metab, 14, 2011
3TDH
  • Download 3tdh
  • View 3tdh
Molmil generated image of 3tdh
STRUCTURE OF THE REGULATORY FRAGMENT OF SCCHAROMYCES CEREVISIAE AMPK IN COMPLEX WITH AMP
Descriptor:Carbon catabolite-derepressing protein kinase, SNF1 protein kinase subunit beta-2, Nuclear protein SNF4, ...
Authors:Mayer, F.V., Heath, R., Underwood, E., Sanders, M.J., Carmena, D., McCartney, R., Leiper, F.C., Xiao, B., Jing, C., Walker, P.A., Haire, L.F., Ogrodowicz, R., Martin, S.R., Schmidt, M.C., Gamblin, S.J., Carling, D.
Deposit date:2011-08-11
Release date:2011-11-09
Last modified:2011-11-23
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:ADP Regulates SNF1, the Saccharomyces cerevisiae Homolog of AMP-Activated Protein Kinase.
Cell Metab, 14, 2011
3TE5
  • Download 3te5
  • View 3te5
Molmil generated image of 3te5
STRUCTURE OF THE REGULATORY FRAGMENT OF SACCHROMYCES CEREVISIAE AMPK IN COMPLEX WITH NADH
Descriptor:Carbon catabolite-derepressing protein kinase, SNF1 protein kinase subunit beta-2, Nuclear protein SNF4, ...
Authors:Mayer, F.V., Heath, R., Underwood, E., Sanders, M.J., Carmena, D., McCartney, R., Leiper, F.C., Xiao, B., Jing, C., Walker, P.A., Haire, L.F., Ogrodowicz, R., Martin, S.R., Schmidt, M.C., Gamblin, S.J., Carling, D.
Deposit date:2011-08-12
Release date:2011-11-09
Last modified:2011-11-23
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:ADP Regulates SNF1, the Saccharomyces cerevisiae Homolog of AMP-Activated Protein Kinase.
Cell Metab, 14, 2011
4B7J
  • Download 4b7j
  • View 4b7j
Molmil generated image of 4b7j
H1N1 2009 PANDEMIC INFLUENZA VIRUS: RESISTANCE OF THE I223R NEURAMINIDASE MUTANT EXPLAINED BY KINETIC AND STRUCTURAL ANALYSIS
Descriptor:NEURAMINIDASE, N-ACETYL-D-GLUCOSAMINE, CALCIUM ION, ...
Authors:van der Vries, E., Vachieri, S.G., Xiong, X., Liu, J., Collins, P.J., Walker, P.A., Haire, L.F., Hay, A.J., Schutten, M., Osterhaus, A.D.M.E., Martin, S.R., Boucher, C.A.B., Skehel, J.J., Gamblin, S.J.
Deposit date:2012-08-20
Release date:2012-10-03
Last modified:2013-07-17
Method:X-RAY DIFFRACTION (2.417 Å)
Cite:H1N1 2009 Pandemic Influenza Virus: Resistance of the I223R Neuraminidase Mutant Explained by Kinetic and Structural Analysis
Plos Pathog., 8, 2012
4B7M
  • Download 4b7m
  • View 4b7m
Molmil generated image of 4b7m
H1N1 2009 PANDEMIC INFLUENZA VIRUS: RESISTANCE OF THE I223R NEURAMINIDASE MUTANT EXPLAINED BY KINETIC AND STRUCTURAL ANALYSIS
Descriptor:NEURAMINIDASE, N-ACETYL-D-GLUCOSAMINE, PHOSPHATE ION, ...
Authors:van der Vries, E., Vachieri, S.G., Xiong, X., Liu, J., Collins, P.J., Walker, P.A., Haire, L.F., Hay, A.J., Schutten, M., Osterhaus, A.D.M.E., Martin, S.R., Boucher, C.A.B., Skehel, J.J., Gamblin, S.J.
Deposit date:2012-08-21
Release date:2012-10-03
Last modified:2012-10-10
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:H1N1 2009 Pandemic Influenza Virus: Resistance of the I223R Neuraminidase Mutant Explained by Kinetic and Structural Analysis
Plos Pathog., 8, 2012
4B7N
  • Download 4b7n
  • View 4b7n
Molmil generated image of 4b7n
H1N1 2009 PANDEMIC INFLUENZA VIRUS: RESISTANCE OF THE I223R NEURAMINIDASE MUTANT EXPLAINED BY KINETIC AND STRUCTURAL ANALYSIS
Descriptor:NEURAMINIDASE, N-ACETYL-D-GLUCOSAMINE, ZANAMIVIR, ...
Authors:van der Vries, E., Vachieri, S.G., Xiong, X., Liu, J., Collins, P.J., Walker, P.A., Haire, L.F., Hay, A.J., Schutten, M., Osterhaus, A.D.M.E., Martin, S.R., Boucher, C.A.B., Skehel, J.J., Gamblin, S.J.
Deposit date:2012-08-21
Release date:2012-10-03
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (2.84 Å)
Cite:H1N1 2009 Pandemic Influenza Virus: Resistance of the I223R Neuraminidase Mutant Explained by Kinetic and Structural Analysis
Plos Pathog., 8, 2012
4B7Q
  • Download 4b7q
  • View 4b7q
Molmil generated image of 4b7q
H1N1 2009 PANDEMIC INFLUENZA VIRUS: RESISTANCE OF THE I223R NEURAMINIDASE MUTANT EXPLAINED BY KINETIC AND STRUCTURAL ANALYSIS
Descriptor:NEURAMINIDASE, N-ACETYL-D-GLUCOSAMINE, ZANAMIVIR, ...
Authors:Liu, J., van der Vries, E., Vachieri, S.G., Xiong, X., Collins, P.J., Walker, P.A., Haire, L.F., Hay, A.J., Schutten, M., Osterhaus, A.D.M.E., Martin, S.R., Boucher, C.A.B., Skehel, J.J., Gamblin, S.J.
Deposit date:2012-08-21
Release date:2012-10-03
Last modified:2012-10-10
Method:X-RAY DIFFRACTION (2.728 Å)
Cite:H1N1 2009 Pandemic Influenza Virus: Resistance of the I223R Neuraminidase Mutant Explained by Kinetic and Structural Analysis
Plos Pathog., 8, 2012
4B7R
  • Download 4b7r
  • View 4b7r
Molmil generated image of 4b7r
H1N1 2009 PANDEMIC INFLUENZA VIRUS: RESISTANCE OF THE I223R NEURAMINIDASE MUTANT EXPLAINED BY KINETIC AND STRUCTURAL ANALYSIS
Descriptor:NEURAMINIDASE, CALCIUM ION, (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid, ...
Authors:Liu, J., van der Vries, E., Vachieri, S.G., Xiong, X., Collins, P.J., Walker, P.A., Haire, L.F., Hay, A.J., Schutten, M., Osterhaus, A.D.M.E., Martin, S.R., Boucher, C.A.B., Skehel, J.J., Gamblin, S.J.
Deposit date:2012-08-21
Release date:2012-10-03
Last modified:2013-07-17
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:H1N1 2009 Pandemic Influenza Virus: Resistance of the I223R Neuraminidase Mutant Explained by Kinetic and Structural Analysis
Plos Pathog., 8, 2012
4B8T
  • Download 4b8t
  • View 4b8t
Molmil generated image of 4b8t
RNA BINDING PROTEIN SOLUTION STRUCTURE OF THE THIRD KH DOMAIN OF KSRP IN COMPLEX WITH THE G-RICH TARGET SEQUENCE.
Descriptor:KH-TYPE SPLICING REGULATORY PROTEIN, 5'-R(*AP*GP*GP*GP*UP)-3'
Authors:Nicastro, G., Garcia-Mayoral, M.F., Hollingworth, D., Kelly, G., Martin, S.R., Briata, P., Gherzi, R., Ramos, A.
Deposit date:2012-08-30
Release date:2012-11-07
Last modified:2013-01-16
Method:SOLUTION NMR
Cite:Noncanonical G Recognition Mediates Ksrp Regulation of Let-7 Biogenesis
Nat.Struct.Mol.Biol., 19, 2012
4BSA
  • Download 4bsa
  • View 4bsa
Molmil generated image of 4bsa
CRYSTAL STRUCTURE OF THE HAEMAGGLUTININ (WITH ASN-133 GLYCOSYLATION) FROM AN H7N9 INFLUENZA VIRUS ISOLATED FROM HUMANS
Descriptor:HEMAGGLUTININ, N-ACETYL-D-GLUCOSAMINE, SULFATE ION
Authors:Xiong, X., Haire, L.F., Martin, S.R., Wharton, S.A., Daniels, R.S., Bennett, M.S., McCauley, J.W., Collins, P.J., Walker, P.A., Skehel, J.J., Gamblin, S.J.
Deposit date:2013-06-10
Release date:2013-07-03
Last modified:2019-05-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Receptor Binding by an H7N9 Influenza Virus from Humans
Nature, 499, 2013
4BSB
  • Download 4bsb
  • View 4bsb
Molmil generated image of 4bsb
HUMAN H7N9 INFLUENZA VIRUS HAEMAGGLUTININ (WITH ASN-133 GLYCOSYLATION) IN COMPLEX WITH HUMAN RECEPTOR ANALOGUE LSTC
Descriptor:HEMAGGLUTININ, N-ACETYL-D-GLUCOSAMINE, O-SIALIC ACID, ...
Authors:Xiong, X., Haire, L.F., Martin, S.R., Wharton, S.A., Daniels, R.S., Bennett, M.S., McCauley, J.W., Collins, P.J., Walker, P.A., Skehel, J.J., Gamblin, S.J.
Deposit date:2013-06-10
Release date:2013-07-03
Last modified:2019-05-22
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Receptor Binding by an H7N9 Influenza Virus from Humans
Nature, 499, 2013
4BSC
  • Download 4bsc
  • View 4bsc
Molmil generated image of 4bsc
HUMAN H7N9 INFLUENZA VIRUS HAEMAGGLUTININ (WITH ASN-133 GLYCOSYLATION) IN COMPLEX WITH HUMAN RECEPTOR ANALOGUE 6'-SLN
Descriptor:HEMAGGLUTININ, N-ACETYL-D-GLUCOSAMINE, O-SIALIC ACID, ...
Authors:Xiong, X., Haire, L.F., Martin, S.R., Wharton, S.A., Daniels, R.S., Bennett, M.S., McCauley, J.W., Collins, P.J., Walker, P.A., Skehel, J.J., Gamblin, S.J.
Deposit date:2013-06-10
Release date:2013-07-03
Last modified:2019-05-22
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Receptor Binding by an H7N9 Influenza Virus from Humans
Nature, 499, 2013
4BSD
  • Download 4bsd
  • View 4bsd
Molmil generated image of 4bsd
HUMAN H7N9 INFLUENZA VIRUS HAEMAGGLUTININ (WITH ASN-133 GLYCOSYLATION) IN COMPLEX WITH AVIAN RECEPTOR ANALOGUE 3'-SLN
Descriptor:HEMAGGLUTININ, N-ACETYL-D-GLUCOSAMINE, O-SIALIC ACID, ...
Authors:Xiong, X., Haire, L.F., Martin, S.R., Wharton, S.A., Daniels, R.S., Bennett, M.S., McCauley, J.W., Collins, P.J., Walker, P.A., Skehel, J.J., Gamblin, S.J.
Deposit date:2013-06-10
Release date:2013-07-03
Last modified:2019-05-22
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Receptor Binding by an H7N9 Influenza Virus from Humans
Nature, 499, 2013
4BSE
  • Download 4bse
  • View 4bse
Molmil generated image of 4bse
HUMAN H7N9 INFLUENZA VIRUS HAEMAGGLUTININ IN COMPLEX WITH HUMAN RECEPTOR ANALOGUE LSTC
Descriptor:HAEMAGGLUTININ HA1, HAEMAGGLUTININ HA2, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Xiong, X., Haire, L.F., Martin, S.R., Wharton, S.A., Daniels, R.S., Bennett, M.S., McCauley, J.W., Collins, P.J., Walker, P.A., Skehel, J.J., Gamblin, S.J.
Deposit date:2013-06-10
Release date:2013-07-03
Last modified:2019-05-22
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Receptor Binding by an H7N9 Influenza Virus from Humans
Nature, 499, 2013
4BSF
  • Download 4bsf
  • View 4bsf
Molmil generated image of 4bsf
HUMAN H7N9 INFLUENZA VIRUS HAEMAGGLUTININ IN COMPLEX WITH AVIAN RECEPTOR ANALOGUE 3'-SLN
Descriptor:HAEMAGGLUTININ HA1, HAEMAGGLUTININ HA2, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Xiong, X., Haire, L.F., Martin, S.R., Wharton, S.A., Daniels, R.S., Bennett, M.S., McCauley, J.W., Collins, P.J., Walker, P.A., Skehel, J.J., Gamblin, S.J.
Deposit date:2013-06-10
Release date:2013-07-03
Last modified:2019-05-22
Method:X-RAY DIFFRACTION (2.76 Å)
Cite:Receptor Binding by an H7N9 Influenza Virus from Humans
Nature, 499, 2013
4BSG
  • Download 4bsg
  • View 4bsg
Molmil generated image of 4bsg
CRYSTAL STRUCTURE OF AN H7N3 AVIAN INFLUENZA VIRUS HAEMAGGLUTININ
Descriptor:HEMAGGLUTININ, N-ACETYL-D-GLUCOSAMINE, SULFATE ION
Authors:Xiong, X., Haire, L.F., Martin, S.R., Wharton, S.A., Daniels, R.S., Bennett, M.S., McCauley, J.W., Collins, P.J., Walker, P.A., Skehel, J.J., Gamblin, S.J.
Deposit date:2013-06-10
Release date:2013-07-03
Last modified:2019-05-22
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Receptor Binding by an H7N9 Influenza Virus from Humans
Nature, 499, 2013
4BSH
  • Download 4bsh
  • View 4bsh
Molmil generated image of 4bsh
H7N3 AVIAN INFLUENZA VIRUS HAEMAGGLUTININ IN COMPLEX WITH HUMAN RECEPTOR ANALOGUE 6'-SLN
Descriptor:HEMAGGLUTININ, N-ACETYL-D-GLUCOSAMINE, O-SIALIC ACID, ...
Authors:Xiong, X., Haire, L.F., Martin, S.R., Wharton, S.A., Daniels, R.S., Bennett, M.S., McCauley, J.W., Collins, P.J., Walker, P.A., Skehel, J.J., Gamblin, S.J.
Deposit date:2013-06-10
Release date:2013-07-03
Last modified:2019-05-22
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Receptor Binding by an H7N9 Influenza Virus from Humans
Nature, 499, 2013
4BSI
  • Download 4bsi
  • View 4bsi
Molmil generated image of 4bsi
H7N3 AVIAN INFLUENZA VIRUS HAEMAGGLUTININ IN COMPLEX WITH AVIAN RECEPTOR ANALOGUE 3'-SLN
Descriptor:HEMAGGLUTININ, N-ACETYL-D-GLUCOSAMINE, SULFATE ION, ...
Authors:Xiong, X., Haire, L.F., Martin, S.R., Wharton, S.A., Daniels, R.S., Bennett, M.S., McCauley, J.W., Collins, P.J., Walker, P.A., Skehel, J.J., Gamblin, S.J.
Deposit date:2013-06-10
Release date:2013-07-03
Last modified:2019-05-22
Method:X-RAY DIFFRACTION (2.62 Å)
Cite:Receptor Binding by an H7N9 Influenza Virus from Humans
Nature, 499, 2013
4CFE
  • Download 4cfe
  • View 4cfe
Molmil generated image of 4cfe
STRUCTURE OF FULL LENGTH HUMAN AMPK IN COMPLEX WITH A SMALL MOLECULE ACTIVATOR, A BENZIMIDAZOLE DERIVATIVE (991)
Descriptor:5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-2, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT BETA-1, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT GAMMA-1, ...
Authors:Xiao, B., Sanders, M.J., Carmena, D., Bright, N.J., Haire, L.F., Underwood, E., Patel, B.R., Heath, R.B., Walker, P.A., Hallen, S., Giordanetto, F., Martin, S.R., Carling, D., Gamblin, S.J.
Deposit date:2013-11-14
Release date:2013-12-25
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (3.023 Å)
Cite:Structural Basis of Ampk Regulation by Small Molecule Activators.
Nat.Commun., 4, 2013
4CFF
  • Download 4cff
  • View 4cff
Molmil generated image of 4cff
STRUCTURE OF FULL LENGTH HUMAN AMPK IN COMPLEX WITH A SMALL MOLECULE ACTIVATOR, A THIENOPYRIDONE DERIVATIVE (A-769662)
Descriptor:5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-2, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT BETA-1, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT GAMMA-1, ...
Authors:Xiao, B., Sanders, M.J., Carmena, D., Bright, N.J., Haire, L.F., Underwood, E., Patel, B.R., Heath, R.B., Walker, P.A., Hallen, S., Giordanetto, F., Martin, S.R., Carling, D., Gamblin, S.J.
Deposit date:2013-11-14
Release date:2013-12-25
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (3.924 Å)
Cite:Structural Basis of Ampk Regulation by Small Molecule Activators.
Nat.Commun., 4, 2013
4CQP
  • Download 4cqp
  • View 4cqp
Molmil generated image of 4cqp
CRYSTAL STRUCTURE OF H5 (VN1194) SER227ASN/GLN196ARG MUTANT HAEMAGGLUTININ
Descriptor:Hemagglutinin HA1, Hemagglutinin HA2, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Xiong, X., Xiao, H., Martin, S.R., Coombs, P.J., Liu, J., Collins, P.J., Vachieri, S.G., Walker, P.A., Lin, Y.P., McCauley, J.W., Gamblin, S.J., Skehel, J.J.
Deposit date:2014-02-21
Release date:2014-05-28
Last modified:2018-11-07
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Enhanced Human Receptor Binding by H5 Haemagglutinins.
Virology, 456, 2014
4CQQ
  • Download 4cqq
  • View 4cqq
Molmil generated image of 4cqq
H5 (VN1194) SER227ASN/GLN196ARG MUTANT HAEMAGGLUTININ IN COMPLEX WITH AVIAN RECEPTOR ANALOGUE 3'SLN
Descriptor:Hemagglutinin HA1, Hemagglutinin HA2, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Xiong, X., Xiao, H., Martin, S.R., Coombs, P.J., Liu, J., Collins, P.J., Vachieri, S.G., Walker, P.A., Lin, Y.P., McCauley, J.W., Gamblin, S.J., Skehel, J.J.
Deposit date:2014-02-21
Release date:2014-05-28
Last modified:2018-11-07
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Enhanced Human Receptor Binding by H5 Haemagglutinins.
Virology, 456, 2014