Author results

4Y20
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COMPLEX OF HUMAN GALECTIN-1 AND NEUACALPHA2-3GALBETA1-4GLC
分子名称:Galectin-1, 5-(ACETYLAMINO)-3,5-DIDEOXYNON-2-ULOPYRANONOSYL-(2->3)-BETA-D-LYXO-HEXOPYRANOSYL-(1->4)HEXOPYRANOSE
著者Lin, H.Y., Hsieh, T.J., Lin, C.H.
登録日2015-02-09
公開日2016-04-06
実験手法X-RAY DIFFRACTION (2.204 Å)
主引用文献Structural basis of human galectin-1 inhibition with Ki values in the micro- to nanomolar range
To Be Published
4Y22
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COMPLEX OF HUMAN GALECTIN-1 AND (3OSO3)GALBETA1-3GLCNAC
分子名称:Galectin-1, O3-SULFONYLGALACTOSE, BETA-METHYL-N-ACETYL-D-GLUCOSAMINE
著者Lin, H.Y., Hsieh, T.J., Lin, C.H.
登録日2015-02-09
公開日2016-04-06
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis of human galectin-1 inhibition with Ki values in the micro- to nanomolar range
To Be Published
4Y26
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COMPLEX OF HUMAN GALECTIN-7 AND GALBETA1-3(6OSO3)GLCNAC
分子名称:Galectin-7, BETA-D-GALACTOSE, methyl 2-(acetylamino)-2-deoxy-6-O-sulfo-beta-D-glucopyranoside
著者Lin, H.Y., Hsieh, T.J., Lin, C.H.
登録日2015-02-09
公開日2016-04-06
実験手法X-RAY DIFFRACTION (2.611 Å)
主引用文献Structural basis of human galectin-1 inhibition with Ki values in the micro- to nanomolar range
To Be Published
2IO7
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E. COLI BIFUNCTIONAL GLUTATHIONYLSPERMIDINE SYNTHETASE/AMIDASE INCOMPLEX WITH MG2+ AND AMPPNP
分子名称:Bifunctional glutathionylspermidine synthetase/amidase, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
著者Pai, C.H., Chiang, B.Y., Ko, T.P., Chong, C.M., Yen, F.J., Coward, J.K., Wang, A.H.-J., Lin, C.H.
登録日2006-10-10
公開日2006-12-12
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Dual binding sites for translocation catalysis by Escherichia coli glutathionylspermidine synthetase
Embo J., 25, 2006
2IO8
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E. COLI BIFUNCTIONAL GLUTATHIONYLSPERMIDINE SYNTHETASE/AMIDASE INCOMPLEX WITH MG2+ AND ADP
分子名称:Bifunctional glutathionylspermidine synthetase/amidase, MAGNESIUM ION, CYSTEINE, ...
著者Pai, C.H., Chiang, B.Y., Ko, T.P., Chou, C.C., Chong, C.M., Yen, F.J., Coward, J.K., Wang, A.H.-J., Lin, C.H.
登録日2006-10-10
公開日2006-12-12
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Dual binding sites for translocation catalysis by Escherichia coli glutathionylspermidine synthetase
Embo J., 25, 2006
2IO9
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E. COLI BIFUNCTIONAL GLUTATHIONYLSPERMIDINE SYNTHETASE/AMIDASE INCOMPLEX WITH MG2+ ,GSH AND ADP
分子名称:Bifunctional glutathionylspermidine synthetase/amidase, MAGNESIUM ION, ADENOSINE-5'-DIPHOSPHATE, ...
著者Pai, C.H., Chiang, B.Y., Ko, T.P., Chou, C.C., Chong, C.M., Yen, F.J., Coward, J.K., Wang, A.H.-J., Lin, C.H.
登録日2006-10-10
公開日2006-12-12
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Dual binding sites for translocation catalysis by Escherichia coli glutathionylspermidine synthetase
Embo J., 25, 2006
2IOA
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E. COLI BIFUNCTIONAL GLUTATHIONYLSPERMIDINE SYNTHETASE/AMIDASE INCOMPLEX WITH MG2+ AND ADP AND PHOSPHINATE INHIBITOR
分子名称:Bifunctional glutathionylspermidine synthetase/amidase, MAGNESIUM ION, D-GAMMA-GLUTAMYL-N-{[(R)-{4-[(4-AMINOBUTYL)AMINO]BUTYL}(PHOSPHONOOXY)PHOSPHORYL]METHYL}-D-ALANINAMIDE, ...
著者Pai, C.H., Chiang, B.Y., Ko, T.P., Chou, C.C., Chong, C.M., Yen, F.J., Coward, J.K., Wang, A.H.-J., Lin, C.H.
登録日2006-10-10
公開日2006-12-12
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Dual binding sites for translocation catalysis by Escherichia coli glutathionylspermidine synthetase
Embo J., 25, 2006
2IOB
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E. COLI BIFUNCTIONAL GLUTATHIONYLSPERMIDINE SYNTHETASE/AMIDASE APO PROTEIN
分子名称:Bifunctional glutathionylspermidine synthetase/amidase
著者Pai, C.H., Chiang, B.Y., Ko, T.P., Chou, C.C., Chong, C.M., Yen, F.J., Coward, J.K., Wang, A.H.-J., Lin, C.H.
登録日2006-10-10
公開日2006-12-12
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Dual binding sites for translocation catalysis by Escherichia coli glutathionylspermidine synthetase
Embo J., 25, 2006
3O98
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GLUTATHIONYLSPERMIDINE SYNTHETASE/AMIDASE C59A COMPLEX WITH ADP AND GSP
分子名称:Bifunctional glutathionylspermidine synthetase/amidase, GLUTATHIONYLSPERMIDINE, ADENOSINE-5'-DIPHOSPHATE, ...
著者Pai, C.H., Lin, C.H., Wang, A.H.-J.
登録日2010-08-04
公開日2011-03-02
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure and mechanism of Escherichia coli glutathionylspermidine amidase belonging to the family of cysteine; histidine-dependent amidohydrolases/peptidases
Protein Sci., 20, 2011
2HWQ
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STRUCTURAL BASIS FOR THE STRUCTURE-ACTIVITY RELATIONSHIPS OF PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR AGONISTS
分子名称:Peroxisome proliferator-activated receptor gamma, [(1-{3-[(6-BENZOYL-1-PROPYL-2-NAPHTHYL)OXY]PROPYL}-1H-INDOL-5-YL)OXY]ACETIC ACID
著者Peng, Y.H., Lu, I.L., Mahindroo, N., Lin, C.H., Hsieh, H.P., Wu, S.Y.
登録日2006-08-01
公開日2007-08-07
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Structural basis for the structure-activity relationships of peroxisome proliferator-activated receptor agonists
J.Med.Chem., 49, 2006
2HWR
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STRUCTURAL BASIS FOR THE STRUCTURE-ACTIVITY RELATIONSHIPS OF PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR AGONISTS
分子名称:Peroxisome proliferator-activated receptor gamma, 2-[(1-{3-[(6-BENZOYL-1-PROPYL-2-NAPHTHYL)OXY]PROPYL}-1H-INDOL-4-YL)OXY]-2-METHYLPROPANOIC ACID
著者Peng, Y.H., Lu, I.L., Mahindroo, N., Lin, C.H., Hsieh, H.P., Wu, S.Y.
登録日2006-08-01
公開日2007-08-07
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.34 Å)
主引用文献Structural basis for the structure-activity relationships of peroxisome proliferator-activated receptor agonists
J.Med.Chem., 49, 2006
2LZK
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NMR SOLUTION STRUCTURE OF AN N2-GUANINE DNA ADDUCT DERIVED FROM THE POTENT TUMORIGEN DIBENZO[A,L]PYRENE: INTERCALATION FROM THE MINOR GROOVE WITH RUPTURED WATSON-CRICK BASE PAIRING
分子名称:DNA (5'-D(*CP*CP*AP*TP*CP*GP*CP*TP*AP*CP*C)-3'), DNA (5'-D(*GP*GP*TP*AP*GP*CP*GP*AP*TP*GP*G)-3'), (11S,12S,13S)-11,12,13,14-tetrahydronaphtho[1,2,3,4-pqr]tetraphene-11,12,13-triol
著者Tang, Y., Liu, Z., Ding, S., Lin, C.H., Cai, Y., Rodriguez, F.A., Sayer, J.M., Jerina, D.M., Amin, S., Broyde, S., Geacintov, N.E.
登録日2012-10-04
公開日2012-11-21
最終更新日2013-02-20
実験手法SOLUTION NMR
主引用文献Nuclear Magnetic Resonance Solution Structure of an N(2)-Guanine DNA Adduct Derived from the Potent Tumorigen Dibenzo[a,l]pyrene: Intercalation from the Minor Groove with Ruptured Watson-Crick Base Pairing.
Biochemistry, 51, 2012
2MIV
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NMR STUDIES OF N2-GUANINE ADDUCTS DERIVED FROM THE TUMORIGEN DIBENZO[A,L]PYRENE IN DNA: IMPACT OF ADDUCT STEREOCHEMISTRY, SIZE, AND LOCAL DNA STRUCTURE ON SOLUTION CONFORMATIONS
分子名称:DNA_(5'-D(*CP*CP*AP*TP*CP*GP*CP*TP*AP*CP*C)-3'), DNA_(5'-D(*GP*GP*TP*AP*GP*GP*AP*TP*GP*G)-3'), (11R,12R,13R)-11,12,13,14-tetrahydronaphtho[1,2,3,4-pqr]tetraphene-11,12,13-triol
著者Rodriguez, F.A., Liu, Z., Lin, C.H., Ding, S., Cai, Y., Kolbanovskiy, A., Kolbanovskiy, M., Amin, S., Broyde, S., Geacintov, N.E.
登録日2013-12-20
公開日2014-04-02
最終更新日2014-04-09
実験手法SOLUTION NMR
主引用文献Nuclear Magnetic Resonance Studies of an N(2)-Guanine Adduct Derived from the Tumorigen Dibenzo[a,l]pyrene in DNA: Impact of Adduct Stereochemistry, Size, and Local DNA Sequence on Solution Conformations.
Biochemistry, 53, 2014
2MIW
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NUCLEAR MAGNETIC RESONANCE STUDIES OF N2-GUANINE ADDUCTS DERIVED FROM THE TUMORIGEN DIBENZO[A,L]PYRENE IN DNA: IMPACT OF ADDUCT STEREOCHEMISTRY, SIZE, AND LOCAL DNA STRUCTURE ON SOLUTION CONFORMATIONS
分子名称:DNA_(5'-D(*CP*CP*AP*TP*CP*GP*CP*TP*AP*CP*C)-3'), DNA_(5'-D(*GP*GP*TP*AP*GP*CP*GP*AP*TP*GP*G)-3'), (11R,12R,13R)-11,12,13,14-tetrahydronaphtho[1,2,3,4-pqr]tetraphene-11,12,13-triol
著者Rodriguez, F.A., Liu, Z., Lin, C.H., Ding, S., Cai, Y., Kolbanovskiy, A., Kolbanovskiy, M., Amin, S., Broyde, S., Geacintov, N.E.
登録日2013-12-20
公開日2014-04-02
最終更新日2014-04-09
実験手法SOLUTION NMR
主引用文献Nuclear Magnetic Resonance Studies of an N(2)-Guanine Adduct Derived from the Tumorigen Dibenzo[a,l]pyrene in DNA: Impact of Adduct Stereochemistry, Size, and Local DNA Sequence on Solution Conformations.
Biochemistry, 53, 2014
2XIB
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CRYSTAL STRUCTURE OF AN ALPHA-L-FUCOSIDASE GH29 FROM BACTEROIDES THETAIOTAOMICRON IN COMPLEX WITH DEOXYFUCONOJIRIMYCIN
分子名称:ALPHA-L-FUCOSIDASE, (2S,3R,4S,5R)-2-METHYLPIPERIDINE-3,4,5-TRIOL, SULFATE ION, ...
著者Lammerts van Bueren, A., Popat, S.D., Lin, C.H., Davies, G.J.
登録日2010-06-28
公開日2010-07-21
最終更新日2012-04-25
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural and Thermodynamic Analyses of Alpha-L-Fucosidase Inhibitors.
Chembiochem, 11, 2010
2XII
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CRYSTAL STRUCTURE OF AN ALPHA-L-FUCOSIDASE GH29 FROM BACTEROIDES THETAIOTAOMICRON IN COMPLEX WITH AN EXTENDED 9-FLUORENONE IMINOSUGAR INHIBITOR
分子名称:ALPHA-L-FUCOSIDASE, TYROSINE, 9-oxo-N-[[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyl-piperidin-2-yl]methyl]fluorene-1-carboxamide, ...
著者Lammerts van Bueren, A., Popat, S.D., Lin, C.H., Davies, G.J.
登録日2010-06-30
公開日2010-07-21
最終更新日2012-04-25
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural and Thermodynamic Analyses of Alpha-L-Fucosidase Inhibitors.
Chembiochem, 11, 2010
3PHL
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THE APO-FORM UDP-GLUCOSE 6-DEHYDROGENASE
分子名称:UDP-glucose 6-dehydrogenase
著者Chen, Y.Y., Ko, T.P., Lin, C.H., Chen, W.H., Wang, A.H.J.
登録日2010-11-04
公開日2011-09-28
最終更新日2019-11-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Conformational change upon product binding to Klebsiella pneumoniae UDP-glucose dehydrogenase: a possible inhibition mechanism for the key enzyme in polymyxin resistance.
J.Struct.Biol., 175, 2011
3UYY
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CRYSTAL STRUCTURES OF BRANCHED-CHAIN AMINOTRANSFERASE FROM DEINOCOCCUS RADIODURANS COMPLEXES WITH ALPHA-KETOISOCAPROATE AND L-GLUTAMATE SUGGEST ITS RADIO-RESISTANCE FOR CATALYSIS
分子名称:Branched-chain-amino-acid aminotransferase, PYRIDOXAL-5'-PHOSPHATE
著者Chen, C.D., Huang, Y.C., Chuankhayan, P., Hsieh, Y.C., Huang, T.F., Lin, C.H., Guan, H.H., Liu, M.Y., Chang, W.C., Chen, C.J.
登録日2011-12-07
公開日2012-12-12
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal Structures of Complexes of the Branched-Chain Aminotransferase from Deinococcus radiodurans with alpha-Ketoisocaproate and L-Glutamate Suggest the Radiation Resistance of This Enzyme for Catalysis
J.Bacteriol., 194, 2012
3UZB
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CRYSTAL STRUCTURES OF BRANCHED-CHAIN AMINOTRANSFERASE FROM DEINOCOCCUS RADIODURANS COMPLEXES WITH ALPHA-KETOISOCAPROATE AND L-GLUTAMATE SUGGEST ITS RADIO-RESISTANCE FOR CATALYSIS
分子名称:Branched-chain-amino-acid aminotransferase, PYRIDOXAL-5'-PHOSPHATE, 2-OXO-4-METHYLPENTANOIC ACID
著者Chen, C.D., Huang, Y.C., Chuankhayan, P., Hsieh, Y.C., Huang, T.F., Lin, C.H., Guan, H.H., Liu, M.Y., Chang, W.C., Chen, C.J.
登録日2011-12-07
公開日2012-12-12
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal Structures of Complexes of the Branched-Chain Aminotransferase from Deinococcus radiodurans with alpha-Ketoisocaproate and L-Glutamate Suggest the Radiation Resistance of This Enzyme for Catalysis
J.Bacteriol., 194, 2012
3UZO
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CRYSTAL STRUCTURES OF BRANCHED-CHAIN AMINOTRANSFERASE FROM DEINOCOCCUS RADIODURANS COMPLEXES WITH ALPHA-KETOISOCAPROATE AND L-GLUTAMATE SUGGEST ITS RADIO-RESISTANCE FOR CATALYSIS
分子名称:Branched-chain-amino-acid aminotransferase, PYRIDOXAL-5'-PHOSPHATE, GLUTAMIC ACID
著者Chen, C.D., Huang, Y.C., Chuankhayan, P., Hsieh, Y.C., Huang, T.F., Lin, C.H., Guan, H.H., Liu, M.Y., Chang, W.C., Chen, C.J.
登録日2011-12-07
公開日2012-12-12
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structures of Complexes of the Branched-Chain Aminotransferase from Deinococcus radiodurans with alpha-Ketoisocaproate and L-Glutamate Suggest the Radiation Resistance of This Enzyme for Catalysis
J.Bacteriol., 194, 2012
2F4B
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CRYSTAL STRUCTURE OF THE LIGAND BINDING DOMAIN OF HUMAN PPAR-GAMMA IN COMPLEX WITH AN AGONIST
分子名称:Peroxisome proliferator-activated receptor gamma, (5-{3-[(6-BENZOYL-1-PROPYL-2-NAPHTHYL)OXY]PROPOXY}-1H-INDOL-1-YL)ACETIC ACID
著者Lu, I.L., Peng, Y.H., Mahindroo, N., Hsieh, H.P., Wu, S.Y.
登録日2005-11-23
公開日2006-02-14
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献Indol-1-yl Acetic Acids as Peroxisome Proliferator-Activated Receptor Agonists: Design, Synthesis, Structural Biology, and Molecular Docking Studies
J.Med.Chem., 49, 2006
2NZW
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CRYSTAL STRUCTURE OF ALPHA1,3-FUCOSYLTRANSFERASE
分子名称:Alpha1,3-fucosyltransferase, SULFATE ION
著者Sun, H.Y., Ko, T.P.
登録日2006-11-27
公開日2007-01-23
最終更新日2017-07-05
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure and mechanism of Helicobacter pylori fucosyltransferase. A basis for lipopolysaccharide variation and inhibitor design.
J. Biol. Chem., 282, 2007
2NZX
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CRYSTAL STRUCTURE OF ALPHA1,3-FUCOSYLTRANSFERASE WITH GDP
分子名称:Alpha1,3-fucosyltransferase, GUANOSINE-5'-DIPHOSPHATE, SULFATE ION
著者Sun, H.Y., Ko, T.P.
登録日2006-11-27
公開日2007-01-23
最終更新日2017-07-05
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure and mechanism of Helicobacter pylori fucosyltransferase. A basis for lipopolysaccharide variation and inhibitor design.
J. Biol. Chem., 282, 2007
2NZY
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CRYSTAL STRUCTURE OF ALPHA1,3-FUCOSYLTRANSFERASE WITH GDP-FUCOSE
分子名称:Alpha1,3-Fucosyltransferase, ALPHA-L-FUCOSE, GUANOSINE-5'-DIPHOSPHATE, ...
著者Sun, H.Y., Ko, T.P.
登録日2006-11-27
公開日2007-01-23
最終更新日2017-07-05
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Structure and mechanism of Helicobacter pylori fucosyltransferase. A basis for lipopolysaccharide variation and inhibitor design.
J. Biol. Chem., 282, 2007
2KQS
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PHOSPHORYLATION OF SUMO-INTERACTING MOTIF BY CK2 ENHANCES DAXX SUMO BINDING ACTIVITY
分子名称:Small ubiquitin-related modifier 1, Death domain-associated protein 6
著者Naik, M.T., Huang, T.H., Shih, H.
登録日2009-11-17
公開日2010-12-01
最終更新日2013-08-21
実験手法SOLUTION NMR
主引用文献Structural and functional roles of Daxx SIM phosphorylation in SUMO paralog-selective binding and apoptosis modulation.
Mol.Cell, 42, 2011