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3D55
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CRYSTAL STRUCTURE OF M. TUBERCULOSIS YEFM ANTITOXIN
分子名称:Uncharacterized protein Rv3357/MT3465, SULFATE ION
著者Kumar, P., Issac, B., Dodson, E.J., Turkenberg, J.P., Mande, S.C.
登録日2008-05-15
公開日2008-12-02
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.13 Å)
主引用文献Crystal structure of Mycobacterium tuberculosis YefM antitoxin reveals that it is not an intrinsically unstructured protein
J.Mol.Biol., 383, 2008
3H3U
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CRYSTAL STRUCTURE OF CRP (CAMP RECEPTOR PROTEIN) FROM MYCOBACTERIUM TUBERCULOSIS
分子名称:PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY CRP/FNR-FAMILY), SULFATE ION, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE
著者Kumar, P., Joshi, D.C., Akif, M., Akhter, Y., Hasnain, S.E., Mande, S.C.
登録日2009-04-17
公開日2010-02-02
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Mapping conformational transitions in cyclic AMP receptor protein: crystal structure and normal-mode analysis of Mycobacterium tuberculosis apo-cAMP receptor protein
Biophys.J., 98, 2010
3LQU
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CRYSTAL STRUCTURE OF 3,4-DIHYDROXY-2-BUTANONE 4-PHOSPHATE SYNTHASE COMPLEXED WITH RIBULOSE-5 PHOSPHATE
分子名称:3,4-dihydroxy-2-butanone 4-phosphate synthase, 5-O-phosphono-D-xylulose
著者Kumar, P., Karthikeyan, S.
登録日2010-02-10
公開日2010-09-15
最終更新日2014-03-05
実験手法X-RAY DIFFRACTION (2.522 Å)
主引用文献Potential anti-bacterial drug target: structural characterization of 3,4-dihydroxy-2-butanone-4-phosphate synthase from Salmonella typhimurium LT2.
Proteins, 78, 2010
3LRJ
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CRYSTAL STRUCTURE OF 3,4-DIHYDROXY-2-BUTANONE 4-PHOSPHATE SYNTHASE IN COMPLEX WITH SULFATE ION.
分子名称:3,4-Dihydroxy-2-butanone 4-phosphate synthase, SULFATE ION
著者Kumar, P., Karthikeyan, S.
登録日2010-02-11
公開日2010-09-15
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (2.803 Å)
主引用文献Potential anti-bacterial drug target: structural characterization of 3,4-dihydroxy-2-butanone-4-phosphate synthase from Salmonella typhimurium LT2.
Proteins, 78, 2010
3LS6
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CRYSTAL STRUCTURE OF 3,4-DIHYDROXY-2-BUTANONE 4-PHOSPHATE SYNTHASE IN COMPLEX WITH SULFATE AND ZINC
分子名称:3,4-Dihydroxy-2-butanone 4-phosphate synthase, SULFATE ION, ZINC ION, ...
著者Kumar, P., Karthikeyan, S.
登録日2010-02-12
公開日2010-09-15
最終更新日2014-03-05
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Potential anti-bacterial drug target: structural characterization of 3,4-dihydroxy-2-butanone-4-phosphate synthase from Salmonella typhimurium LT2.
Proteins, 78, 2010
3MK3
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CRYSTAL STRUCTURE OF LUMAZINE SYNTHASE FROM SALMONELLA TYPHIMURIUM LT2
分子名称:6,7-dimethyl-8-ribityllumazine synthase, SULFATE ION
著者Kumar, P., Singh, M., Karthikeyan, S.
登録日2010-04-14
公開日2011-02-02
最終更新日2013-01-23
実験手法X-RAY DIFFRACTION (3.569 Å)
主引用文献Crystal structure analysis of icosahedral lumazine synthase from Salmonella typhimurium, an antibacterial drug target.
Acta Crystallogr.,Sect.D, 67, 2011
3NQ4
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30MER STRUCTURE OF LUMAZINE SYNTHASE FROM SALMONELLA TYPHIMURIUM LT2
分子名称:6,7-dimethyl-8-ribityllumazine synthase, SULFATE ION
著者Kumar, P., Singh, M., Karthikeyan, S.
登録日2010-06-29
公開日2011-06-08
最終更新日2013-01-23
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Crystal structure of Lumazine synthase from Salmonella typhimurium LT2
To be Published
4R7E
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STRUCTURE OF BRE1 RING DOMAIN
分子名称:E3 ubiquitin-protein ligase BRE1, ZINC ION
著者Kumar, P., Wolberger, C.
登録日2014-08-27
公開日2015-05-13
最終更新日2015-08-26
実験手法X-RAY DIFFRACTION (2.251 Å)
主引用文献Structure of the yeast Bre1 RING domain.
Proteins, 83, 2015
5DU7
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CRYSTAL STRUCTURE OF LDTMT2 AT 1.79 ANGSTROM RESOLUTION
分子名称:L,D-transpeptidase 2
著者Kumar, P., Lamichhane, G.
登録日2015-09-18
公開日2016-09-28
最終更新日2017-09-20
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Non-classical transpeptidases yield insight into new antibacterials.
Nat. Chem. Biol., 13, 2017
5DUJ
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CRYSTAL STRUCTURE OF LDTMT2 IN COMPLEX WITH FAROPENEM ADDUCT
分子名称:L,D-transpeptidase 2, SULFATE ION, BETA-MERCAPTOETHANOL, ...
著者Kumar, P., Lamichhane, G.
登録日2015-09-18
公開日2016-09-28
最終更新日2017-09-20
実験手法X-RAY DIFFRACTION (2.17 Å)
主引用文献Non-classical transpeptidases yield insight into new antibacterials.
Nat. Chem. Biol., 13, 2017
5DVP
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CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS L,D-TRANSPEPTIDASE 2 WITH DORIPENEM ADDUCT
分子名称:L,D-transpeptidase 2, (2S,3R,4S)-2-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-3-methyl-4-({(3S,5S)-5-[(sulfamoylamino)methyl]pyrrolidin-3-yl}sulfanyl)-3,4-dihydro-2H-pyrrole-5-carboxylic acid, SULFATE ION, ...
著者Kumar, P., Lamichhane, G.
登録日2015-09-21
公開日2016-09-28
最終更新日2017-09-20
実験手法X-RAY DIFFRACTION (2.18 Å)
主引用文献Non-classical transpeptidases yield insight into new antibacterials.
Nat. Chem. Biol., 13, 2017
5DZJ
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CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS L,D-TRANSPEPTIDASE 2 WITH CARBAPENEM DRUG T206 IN CONFORMATION A
分子名称:L,D-transpeptidase 2, (2~{R},3~{R},4~{R})-4-methyl-3-(2-oxidanylidene-2-propoxy-ethyl)sulfanyl-5-[(2~{S},3~{R})-3-oxidanyl-1-oxidanylidene-butan-2-yl]-3,4-dihydro-2~{H}-pyrrole-2-carboxylic acid
著者Kumar, P., Ginell, S.L., Lamichhane, G.
登録日2015-09-25
公開日2016-10-05
最終更新日2017-09-20
実験手法X-RAY DIFFRACTION (2.095 Å)
主引用文献Non-classical transpeptidases yield insight into new antibacterials.
Nat. Chem. Biol., 13, 2017
5DZP
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CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS L,D-TRANSPEPTIDASE 2 WITH CARBAPENEM DRUG T206 IN CONFORMATION B
分子名称:L,D-transpeptidase 2, (2~{R},3~{R},4~{R})-4-methyl-3-(2-oxidanylidene-2-propoxy-ethyl)sulfanyl-5-[(2~{S},3~{R})-3-oxidanyl-1-oxidanylidene-butan-2-yl]-3,4-dihydro-2~{H}-pyrrole-2-carboxylic acid
著者Kumar, P., Ginell, S.L., Lamichhane, G.
登録日2015-09-25
公開日2016-10-05
最終更新日2017-09-20
実験手法X-RAY DIFFRACTION (2.19 Å)
主引用文献Non-classical transpeptidases yield insight into new antibacterials.
Nat. Chem. Biol., 13, 2017
5E1G
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CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS L,D-TRANSPEPTIDASE 2 WITH CARBAPENEM DRUG T208
分子名称:L,D-transpeptidase 2, (2~{S},3~{R},4~{R})-4-(2-cyclohexyloxy-2-oxidanylidene-ethyl)sulfanyl-3-methyl-2-[(2~{S},3~{R})-3-oxidanyl-1-oxidanylidene-butan-2-yl]-3,4-dihydro-2~{H}-pyrrole-5-carboxylic acid
著者Kumar, P., Lamichhane, G., Ginell, S.L.
登録日2015-09-29
公開日2016-10-12
最終更新日2017-09-20
実験手法X-RAY DIFFRACTION (1.852 Å)
主引用文献Non-classical transpeptidases yield insight into new antibacterials.
Nat. Chem. Biol., 13, 2017
5E1I
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CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS L,D-TRANSPEPTIDASE 2 WITH CARBAPENEM DRUG T210
分子名称:L,D-transpeptidase 2, SODIUM ION, (2S,3R,4R)-2-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-3-methyl-4-(methylsulfanyl)-3,4-dihydro-2H-pyrrole-5-carboxylic acid, ...
著者Kumar, P., Ginell, S.L., Lamichhane, G.
登録日2015-09-29
公開日2016-10-12
最終更新日2017-09-20
実験手法X-RAY DIFFRACTION (2.003 Å)
主引用文献Non-classical transpeptidases yield insight into new antibacterials.
Nat. Chem. Biol., 13, 2017
5E51
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CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS L,D-TRANSPEPTIDASE 1 WITH FAROPENEM ADDUCT
分子名称:L,D-transpeptidase 1, (3R)-3-hydroxybutanal
著者Kumar, P., Lamichhane, G., Ginell, S.L.
登録日2015-10-07
公開日2016-10-26
最終更新日2017-09-13
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Non-classical transpeptidases yield insight into new antibacterials.
Nat. Chem. Biol., 13, 2017
5E5L
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CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS L,D-TRANSPEPTIDASE 1 AT 1.89 ANGSTROM
分子名称:L,D-transpeptidase 1
著者Kumar, P., Lamichhane, G., Ginell, S.L.
登録日2015-10-08
公開日2016-10-26
最終更新日2017-09-20
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献Non-classical transpeptidases yield insight into new antibacterials.
Nat. Chem. Biol., 13, 2017
5UWV
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CRYSTAL STRUCTURE OF MYCOBACTERIUM ABSCESSUS L,D-TRANSPEPTIDASE 2
分子名称:L,D-TRANSPEPTIDASE 2
著者Kumar, P., Ginell, L.S., Lamichhane, G.
登録日2017-02-21
公開日2017-08-16
最終更新日2017-10-04
実験手法X-RAY DIFFRACTION (2.98 Å)
主引用文献Mycobacterium abscessus l,d-Transpeptidases Are Susceptible to Inactivation by Carbapenems and Cephalosporins but Not Penicillins.
Antimicrob. Agents Chemother., 61, 2017
2YFI
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CRYSTAL STRUCTURE OF BIPHENYL DIOXYGENASE VARIANT RR41 (BPDO-RR41)
分子名称:BIPHENYL DIOXYGENASE SUBUNIT ALPHA, BIPHENYL DIOXYGENASE SUBUNIT BETA, FE2/S2 (INORGANIC) CLUSTER, ...
著者Kumar, P., Bolin, J.T.
登録日2011-04-06
公開日2011-06-08
最終更新日2011-08-10
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Retuning Rieske-Type Oxygenases to Expand Substrate Range.
J.Biol.Chem., 286, 2011
2YFJ
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CRYSTAL STRUCTURE OF BIPHENYL DIOXYGENASE VARIANT RR41 WITH DIBENZOFURAN
分子名称:BIPHENYL DIOXYGENASE SUBUNIT ALPHA, BIPHENYL DIOXYGENASE SUBUNIT BETA, FE2/S2 (INORGANIC) CLUSTER, ...
著者Kumar, P., Sylvestre, M., Bolin, J.T.
登録日2011-04-06
公開日2011-06-08
最終更新日2011-08-10
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Retuning Rieske-Type Oxygenases to Expand Substrate Range.
J.Biol.Chem., 286, 2011
3GZX
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CRYSTAL STRUCTURE OF THE BIPHENYL DIOXYGENASE IN COMPLEX WITH BIPHENYL FROM COMAMONAS TESTOSTERONI SP. STRAIN B-356
分子名称:Biphenyl dioxygenase subunit alpha, Biphenyl dioxygenase subunit beta, FE (II) ION, ...
著者Kumar, P., Colbert, C.L., Bolin, J.T.
登録日2009-04-08
公開日2010-05-05
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献Structural Characterization of Pandoraea pnomenusa B-356 Biphenyl Dioxygenase Reveals Features of Potent Polychlorinated Biphenyl-Degrading Enzymes
Plos One, 8, 2013
3GZY
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CRYSTAL STRUCTURE OF THE BIPHENYL DIOXYGENASE FROM COMAMONAS TESTOSTERONI SP. STRAIN B-356
分子名称:Biphenyl dioxygenase subunit alpha, Biphenyl dioxygenase subunit beta, FE (II) ION, ...
著者Kumar, P., Colbert, C.L., Bolin, J.T.
登録日2009-04-08
公開日2010-05-05
最終更新日2013-02-06
実験手法X-RAY DIFFRACTION (1.62 Å)
主引用文献Structural Characterization of Pandoraea pnomenusa B-356 Biphenyl Dioxygenase Reveals Features of Potent Polychlorinated Biphenyl-Degrading Enzymes
Plos One, 8, 2013
5AEU
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CRYSTAL STRUCTURE OF II9 VARIANT OF BIPHENYL DIOXYGENASE FROM BURKHOLDERIA XENOVORANS LB400
分子名称:BIPHENYL DIOXYGENASE SUBUNIT ALPHA, BIPHENYL DIOXYGENASE SUBUNIT BETA, FE2/S2 (INORGANIC) CLUSTER, ...
著者Dhindwal, S., Gomez-Gil, L., Sylvestre, M., Eltis, L.D., Bolin, J.T., Kumar, P.
登録日2015-01-10
公開日2016-04-06
最終更新日2016-05-11
実験手法X-RAY DIFFRACTION (2.49 Å)
主引用文献Structural Basis of the Enhanced Pollutant-Degrading Capabilities of an Engineered Biphenyl Dioxygenase
J.Bacteriol., 198, 2016
5K69
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CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS L,D-TRANSPEPTIDASE 2 WITH CARBAPENEM DRUG T224
分子名称:L,D-transpeptidase 2, GLYCEROL, (2~{S},3~{R},4~{R})-4-(1~{H}-indol-3-ylsulfanyl)-3-methyl-2-[(2~{S},3~{S})-3-oxidanyl-1-oxidanylidene-butan-2-yl]-3,4-dihydro-2~{H}-pyrrole-5-carboxylic acid
著者Lamichhane, G., Ginell, S.L., Kumar, P.
登録日2016-05-24
公開日2016-11-09
最終更新日2017-09-20
実験手法X-RAY DIFFRACTION (2.001 Å)
主引用文献Non-classical transpeptidases yield insight into new antibacterials.
Nat. Chem. Biol., 13, 2017
6BBR
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ROOM TEMPERATURE NEUTRON/X-RAY STRUCTURE OF AAC-VIA
分子名称:AAC 3-VI protein, MAGNESIUM ION
著者Cuneo, M.J., Kumar, P., Serpersu, E.H.
登録日2017-10-19
公開日2018-02-28
最終更新日2018-09-12
実験手法X-RAY DIFFRACTION (2.002 Å), NEUTRON DIFFRACTION
主引用文献A low-barrier hydrogen bond mediates antibiotic resistance in a noncanonical catalytic triad.
Sci Adv, 4, 2018