8AQF
| CRYSTAL STRUCTURE OF HUMAN MONOGLYCERIDE LIPASE WITH COMPOUND LEI-515 | Descriptor: | 1-[(~{R})-[2-chloranyl-4-[(2~{S},3~{S})-4-(3-chlorophenyl)-2,3-dimethyl-piperazin-1-yl]carbonyl-phenyl]sulfinyl]-3,3-bis(fluoranyl)pentan-2-one, Monoglyceride lipase | Authors: | Jiang, M, Huizenga, M, Wirt, J, Paloczi, J, Amedi, A, van der Berg, R, Benz, J, Collin, L, Deng, H, Driever, W, Florea, B, Grether, U, Janssen, A, Heitman, L, Lam, T.W, Mohr, F, Pavlovic, A, Ruf, I, Rutjes, H, Stevens, F, van der Vliet, D, van der Wel, T, Wittwer, M, Boeckel, C, Pacher, P, Hohmann, A, van der Stelt, M. | Deposit date: | 2022-08-12 | Release date: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Discovery of a peripheral restricted, reversible monoacylglycerol lipase inhibitor that reduces liver injury and chemotherapy-induced neuropathy To Be Published
|
|
7N95
| state 1 of TcdB and FZD2 at pH5 | Descriptor: | Frizzled-2, Toxin B | Authors: | Jiang, M, Zhang, J. | Deposit date: | 2021-06-16 | Release date: | 2022-03-02 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Structural Basis for Receptor Recognition of Clostridium difficile Toxin B and its Dissociation upon Acidification To Be Published
|
|
7N9Q
| State 3 of TcdB and FZD2 at pH5 | Descriptor: | Toxin B | Authors: | Jiang, M, Zhang, J. | Deposit date: | 2021-06-18 | Release date: | 2022-03-02 | Method: | ELECTRON MICROSCOPY (4.6 Å) | Cite: | Structural Basis for Receptor Recognition of Clostridium difficile Toxin B and its Dissociation upon Acidification To Be Published
|
|
7N97
| State 2 of TcdB and FZD2 at pH5 | Descriptor: | Frizzled-2, Toxin B | Authors: | Jiang, M, Zhang, J. | Deposit date: | 2021-06-17 | Release date: | 2022-03-02 | Method: | ELECTRON MICROSCOPY (5.1 Å) | Cite: | Structural Basis for Receptor Recognition of the Clostridium difficile Toxin B and its Dissociation upon Acidification To Be Published
|
|
7N9R
| state 4 of TcdB and FZD2 at pH5 | Descriptor: | Toxin B | Authors: | Jiang, M, Zhang, J. | Deposit date: | 2021-06-18 | Release date: | 2022-03-02 | Method: | ELECTRON MICROSCOPY (5.9 Å) | Cite: | Structural Basis for Receptor Recognition of Clostridium difficile Toxin B and its Dissociation upon Acidification To Be Published
|
|
7N9S
| TcdB and frizzled-2 CRD complex | Descriptor: | Frizzled-2, Toxin B | Authors: | Jiang, M, Zhang, J. | Deposit date: | 2021-06-18 | Release date: | 2022-03-02 | Method: | ELECTRON MICROSCOPY (5.1 Å) | Cite: | Structural Basis for Receptor Recognition of Clostridium difficile Toxin B and its Dissociation upon Acidification To Be Published
|
|
7N9Y
| Full-length TcdB and CSPG4 (401-560) complex | Descriptor: | Chondroitin sulfate proteoglycan 4, Toxin B | Authors: | Jiang, M, Zhang, J. | Deposit date: | 2021-06-18 | Release date: | 2022-03-02 | Method: | ELECTRON MICROSCOPY (4.8 Å) | Cite: | Structural Basis for Receptor Recognition of Clostridium difficile Toxin B and its Dissociation upon Acidification To Be Published
|
|
7N8X
| Partial C. difficile TcdB and CSPG4 fragment | Descriptor: | Chondroitin sulfate proteoglycan 4, Toxin B | Authors: | Jiang, M, Zhang, J. | Deposit date: | 2021-06-16 | Release date: | 2022-03-02 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structural Basis for Receptor Recognition of Clostridium difficile Toxin B and its Dissociation upon Acidification To Be Published
|
|
1EHC
| STRUCTURE OF SIGNAL TRANSDUCTION PROTEIN CHEY | Descriptor: | CHEY, SULFATE ION | Authors: | Jiang, M, Bourret, R, Simon, M, Volz, K. | Deposit date: | 1996-03-05 | Release date: | 1997-05-15 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.26 Å) | Cite: | Uncoupled phosphorylation and activation in bacterial chemotaxis. The 2.3 A structure of an aspartate to lysine mutant at position 13 of CheY. J.Biol.Chem., 272, 1997
|
|
8FH3
| Human IFT-A complex structures provide molecular insights into ciliary transport | Descriptor: | Intraflagellar transport protein 122 homolog, Intraflagellar transport protein 140 homolog, Tubby-related protein 3, ... | Authors: | Jiang, M, Palicharla, V.R, Miller, D, Hwang, S.H, Zhu, H, Hixson, P, Mukhopadhyay, S, Sun, J. | Deposit date: | 2022-12-13 | Release date: | 2023-02-22 | Last modified: | 2023-04-12 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | Human IFT-A complex structures provide molecular insights into ciliary transport. Cell Res., 33, 2023
|
|
8FGW
| Human IFT-A complex structures provide molecular insights into ciliary transport | Descriptor: | Intraflagellar transport protein 122 homolog, Intraflagellar transport protein 140 homolog, Intraflagellar transport protein 43 homolog, ... | Authors: | Jiang, M, Palicharla, V.R, Miller, D, Hwang, S.H, Zhu, H, Hixson, P, Mukhopadhyay, S, Sun, J. | Deposit date: | 2022-12-12 | Release date: | 2023-02-22 | Last modified: | 2023-04-12 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Human IFT-A complex structures provide molecular insights into ciliary transport. Cell Res., 33, 2023
|
|
7UJJ
| Stx2a and DARPin complex | Descriptor: | 1,2-ETHANEDIOL, 3-PYRIDINIUM-1-YLPROPANE-1-SULFONATE, DARPin, ... | Authors: | Jiang, M, Zhang, J. | Deposit date: | 2022-03-30 | Release date: | 2023-04-12 | Method: | ELECTRON MICROSCOPY (6.5 Å) | Cite: | A Multi-Specific DARPin Potently Neutralizes Shiga Toxin 2 via Simultaneous Modulation of Both Toxin Subunits. Bioengineering (Basel), 9, 2022
|
|
8CB2
| |
8DOL
| Mechanism of regulation of the Helicobacter pylori Cagbeta ATPase by CagZ | Descriptor: | Cag pathogenicity island protein (Cag5), DI(HYDROXYETHYL)ETHER, SULFATE ION | Authors: | Wu, X, Zhao, Y, Yang, W, Sun, L, Ye, X, Jiang, M, Wang, Q, Wang, Q, Zhang, X, Wu, Y. | Deposit date: | 2022-07-13 | Release date: | 2023-02-15 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Mechanism of regulation of the Helicobacter pylori Cag beta ATPase by CagZ. Nat Commun, 14, 2023
|
|
1M5Z
| The PDZ7 of Glutamate Receptor Interacting Protein Binds to its Target via a Novel Hydrophobic Surface Area | Descriptor: | AMPA receptor interacting protein | Authors: | Feng, W, Fan, J, Jiang, M, Shi, Y, Zhang, M. | Deposit date: | 2002-07-11 | Release date: | 2002-11-06 | Last modified: | 2022-02-23 | Method: | SOLUTION NMR | Cite: | The PDZ7 of Glutamate Receptor Interacting Protein Binds to its Target via a Novel Hydrophobic Surface Area J.Biol.Chem., 277, 2002
|
|
3FIF
| Crystal structure of the ygdR protein from E.coli. Northeast Structural Genomics target ER382A. | Descriptor: | Uncharacterized ligand, Uncharacterized lipoprotein ygdR | Authors: | Kuzin, A.P, Su, M, Seetharaman, J, Rossi, P, Chen, C.X, Jiang, M, Cunningham, K, Ma, L, Xiao, R, Liu, J.C, Baran, M, Swapna, G.V.T, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2008-12-11 | Release date: | 2009-01-06 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structure of the ygdR protein from E.coli. Northeast Structural Genomics target ER382A. To be Published
|
|
2NWT
| NMR Structure of Protein UPF0165 protein AF_2212 from Archaeoglobus Fulgidus; Northeast Structural Genomics Consortium Target GR83 | Descriptor: | UPF0165 protein AF_2212 | Authors: | Singarapu, K.K, Sukumaran, D.K, Parish, D, Atreya, H.S, Liu, G, Eletsky, A, Chen, C.X, Jiang, M, Cunningham, K, Xiao, R, Swapna, G.V.T, Acton, T.B, Rost, B, Montelione, G.T, Szyperski, T, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2006-11-16 | Release date: | 2007-01-30 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | NMR Structure of Protein Y2212_ARCFU from Archaeoglobus Fulgidus; Northeast Structural Genomics Consortium Target GR83 To be Published
|
|
3NNQ
| Crystal Structure of the N-terminal domain of Moloney murine leukemia virus integrase, Northeast Structural Genomics Consortium Target OR3 | Descriptor: | ACETATE ION, N-terminal domain of Moloney murine leukemia virus integrase, ZINC ION | Authors: | Guan, R, Xiao, R, Acton, T, Jiang, M, Roth, M, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2010-06-24 | Release date: | 2010-07-14 | Last modified: | 2023-07-26 | Method: | X-RAY DIFFRACTION (2.693 Å) | Cite: | X-ray crystal structure of the N-terminal region of Moloney murine leukemia virus integrase and its implications for viral DNA recognition. Proteins, 85, 2017
|
|
4NZG
| Crystal Structure of the N-terminal domain of Moloney murine leukemia virus integrase, Northeast Structural Genomics Consortium Target OR3 | Descriptor: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, ACETATE ION, Integrase p46, ... | Authors: | Guan, R, Jiang, M, Janjua, H, Maglaqui, M, Zhao, L, Xiao, R, Acton, T.B, Everett, J.K, Roth, M, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2013-12-12 | Release date: | 2014-02-05 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.152 Å) | Cite: | X-ray crystal structure of the N-terminal region of Moloney murine leukemia virus integrase and its implications for viral DNA recognition. Proteins, 85, 2017
|
|
2LEK
| Solution NMR structure of a Thiamine Biosynthesis (ThiS) Protein RPA3574 from Rhodopseudomonas palustris refined with NH RDCs. Northeast Structural Genomics Consortium target RpR325 | Descriptor: | Putative thiamin biosynthesis ThiS | Authors: | Ramelot, T.A, Cort, J.R, Lee, H, Wang, H, Ciccosanti, C, Jiang, M, Nair, R, Rost, B, Acton, T.B, Xiao, R, Swapna, G, Everett, J.K, Prestegard, J.H, Montelione, G.T, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2011-06-16 | Release date: | 2011-06-29 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Solution NMR structure of a Thiamine Biosynthesis (ThiS) Protein RPA3574 from Rhodopseudomonas palustris. Northeast Structural Genomics Consortium target RpR325 To be Published
|
|
6IQT
| Crystal Structure of CagV, a VirB8 homolog of T4SS from Helicobacter pylori Strain 26695 | Descriptor: | Cag pathogenicity island protein (Cag10) | Authors: | Wu, X, Zhao, Y, Sun, L, Jiang, M, Wang, Q, Wang, Q, Yang, W, Wu, Y. | Deposit date: | 2018-11-08 | Release date: | 2019-11-13 | Last modified: | 2020-04-29 | Method: | X-RAY DIFFRACTION (1.922 Å) | Cite: | Crystal structure of CagV, the Helicobacter pylori homologue of the T4SS protein VirB8. Febs J., 286, 2019
|
|
2K1G
| Solution NMR structure of lipoprotein spr from Escherichia coli K12. Northeast Structural Genomics target ER541-37-162 | Descriptor: | Lipoprotein spr | Authors: | Aramini, J.M, Rossi, P, Zhao, L, Jiang, M, Maglaqui, M, Xiao, R, Liu, J, Baran, M.C, Swapna, G.V.T, Huang, Y.J, Acton, T.B, Rost, B, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2008-03-03 | Release date: | 2008-03-18 | Last modified: | 2011-07-13 | Method: | SOLUTION NMR | Cite: | Solution NMR structure of the NlpC/P60 domain of lipoprotein Spr from Escherichia coli: structural evidence for a novel cysteine peptidase catalytic triad. Biochemistry, 47, 2008
|
|
2JPU
| solution structure of NESG target SsR10, Orf c02003 protein | Descriptor: | Orf c02003 protein | Authors: | Wu, Y, Singarapu, K.K, Zhang, Q, Eletski, A, Xu, D, Sukumaran, D, Parish, D, Wang, D, Jiang, M, Cunningham, K, Maglaqui, M, Owens, L, Xiao, R, Liu, J, Baran, M, Swapna, G.V.T, Acton, T, Rost, B, Montelione, G, Szyperski, T, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2007-05-23 | Release date: | 2007-07-03 | Last modified: | 2023-12-20 | Method: | SOLUTION NMR | Cite: | Solution structure of NESG target SsR10, Orf c02003 protein To be Published
|
|
2DO8
| Solution Structure of UPF0301 protein HD_1794 | Descriptor: | UPF0301 protein HD_1794 | Authors: | Zhang, Q, Liu, G, Shastry, R, Jiang, M, Cunningham, K, Ma, L.C, Xiao, R, Acton, T.R, Montelione, G.T, Szyperski, T, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2006-04-27 | Release date: | 2006-05-25 | Last modified: | 2022-03-09 | Method: | SOLUTION NMR | Cite: | Solution Structure of UPF0301 protein HD_1794 To be published
|
|
2HF1
| Crystal structure of the putative Tetraacyldisaccharide-1-P 4-kinase from Chromobacterium violaceum. NESG target CvR39. | Descriptor: | Tetraacyldisaccharide-1-P 4-kinase, ZINC ION | Authors: | Vorobiev, S.M, Abashidze, M, Seetharaman, J, Chen, C.X, Jiang, M, Cunningham, K, Ma, L.C, Xiao, R, Acton, T, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2006-06-22 | Release date: | 2006-08-22 | Last modified: | 2018-01-24 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of the putative Tetraacyldisaccharide-1-P 4-kinase from Chromobacterium
violaceum. To be Published
|
|