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1K0R
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CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS NUSA
分子名称:NusA, SULFATE ION
著者Gopal, B., Haire, L.F., Gamblin, S.J., Dodson, E.J., Lane, A.N., Papavinasasundaram, K.G., Colston, M.J., Dodson, G., TB Structural Genomics Consortium (TBSGC)
登録日2001-09-20
公開日2001-12-21
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structure of the transcription elongation/anti-termination factor NusA from Mycobacterium tuberculosis at 1.7 A resolution.
J.Mol.Biol., 314, 2001
1O9K
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CRYSTAL STRUCTURE OF THE RETINOBLASTOMA TUMOUR SUPPRESSOR PROTEIN BOUND TO E2F PEPTIDE
分子名称:RETINOBLASTOMA-ASSOCIATED PROTEIN, TRANSCRIPTION FACTOR E2F1
著者Xiao, B., Spencer, J., Clements, A., Ali-Khan, N., Mittnacht, S., Broceno, C., Burghammer, M., Perrakis, A., Marmorstein, R., Gamblin, S.J.
登録日2002-12-16
公開日2003-03-06
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal Structure of the Retinoblastoma Tumor Suppressor Protein Bound to E2F and the Molecular Basis of its Regulation
Proc.Natl.Acad.Sci.USA, 100, 2003
1O9S
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CRYSTAL STRUCTURE OF A TERNARY COMPLEX OF THE HUMAN HISTONE METHYLTRANSFERASE SET7/9
分子名称:HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-4 SPECIFIC, GENE FRAGMENT FOR HISTONE H3, ...
著者Xiao, B., Jing, C., Wilson, J.R., Walker, P.A., Vasisht, N., Kelly, G., Howell, S., Taylor, I.A., Blackburn, G.M., Gamblin, S.J.
登録日2002-12-18
公開日2003-02-06
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structure and Catalytic Mechanism of the Human Histone Methyltransferase Set7/9
Nature, 421, 2003
1SML
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METALLO BETA LACTAMASE L1 FROM STENOTROPHOMONAS MALTOPHILIA
分子名称:PROTEIN (PENICILLINASE), ZINC ION
著者Ullah, J.H., Walsh, T.R., Taylor, I.A., Emery, D.C., Verma, C.S., Gamblin, S.J., Spencer, J.
登録日1998-09-22
公開日1999-09-20
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The crystal structure of the L1 metallo-beta-lactamase from Stenotrophomonas maltophilia at 1.7 A resolution.
J.Mol.Biol., 284, 1998
1SVA
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SIMIAN VIRUS 40
分子名称:SIMIAN VIRUS 40
著者Stehle, T., Gamblin, S.J., Harrison, S.C.
登録日1995-11-27
公開日1996-06-10
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献The structure of simian virus 40 refined at 3.1 A resolution.
Structure, 4, 1996
1TI8
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H7 HAEMAGGLUTININ
分子名称:hemagglutinin, 2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE, ALPHA-D-MANNOSE, ...
著者Russell, R.J., Gamblin, S.J., Haire, L.F., Stevens, D.J., Xaio, B., Ha, Y., Skehel, J.J.
登録日2004-06-02
公開日2005-06-21
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献H1 and H7 influenza haemagglutinin structures extend a structural classification of haemagglutinin subtypes.
Virology, 325, 2004
1XQH
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CRYSTAL STRUCTURE OF A TERNARY COMPLEX OF THE METHYLTRANSFERASE SET9 (ALSO KNOWN AS SET7/9) WITH A P53 PEPTIDE AND SAH
分子名称:Histone-lysine N-methyltransferase, H3 lysine-4 specific, 9-mer peptide from tumor protein p53, ...
著者Chuikov, S., Kurash, J.K., Wilson, J.R., Xiao, B., Justin, N., Ivanov, G.S., McKinney, K., Tempst, P., Prives, C., Gamblin, S.J., Barlev, N.A., Reinberg, D.
登録日2004-10-12
公開日2004-11-23
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Regulation of p53 activity through lysine methylation
Nature, 432, 2004
2AIO
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METALLO BETA LACTAMASE L1 FROM STENOTROPHOMONAS MALTOPHILIA COMPLEXED WITH HYDROLYZED MOXALACTAM
分子名称:Metallo-beta-lactamase L1, ZINC ION, SULFATE ION, ...
著者Spencer, J., Read, J., Sessions, R.B., Howell, S., Blackburn, G.M., Gamblin, S.J.
登録日2005-07-30
公開日2005-10-11
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Antibiotic Recognition by Binuclear Metallo-beta-Lactamases Revealed by X-ray Crystallography
J.Am.Chem.Soc., 127, 2005
2BQZ
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CRYSTAL STRUCTURE OF A TERNARY COMPLEX OF THE HUMAN HISTONE METHYLTRANSFERASE PR-SET7 (ALSO KNOWN AS SET8)
分子名称:SET8 PROTEIN, HISTONE H4, S-ADENOSYL-L-HOMOCYSTEINE
著者Xiao, B., Jing, C., Kelly, G., Walker, P.A., Muskett, F.W., Frenkiel, T.A., Martin, S.R., Sarma, K., Reinberg, D., Gamblin, S.J., Wilson, J.R.
登録日2005-04-28
公開日2005-06-08
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Specificity and Mechanism of the Histone Methyltransferase Pr-Set7
Genes Dev., 19, 2005
2HT5
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N8 NEURAMINIDASE
分子名称:Neuraminidase, 2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE, CALCIUM ION
著者Russell, R.J., Haire, L.F., Stevens, D.J., Collins, P.J., Lin, Y.P., Blackburn, G.M., Hay, A.J., Gamblin, S.J., Skehel, J.J.
登録日2006-07-25
公開日2006-09-05
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design.
Nature, 443, 2006
2HT7
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N8 NEURAMINIDASE IN OPEN COMPLEX WITH OSELTAMIVIR
分子名称:Neuraminidase, (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid
著者Russell, R.J., Haire, L.F., Stevens, D.J., Collins, P.J., Lin, Y.P., Blackburn, G.M., Hay, A.J., Gamblin, S.J., Skehel, J.J.
登録日2006-07-25
公開日2006-09-05
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design.
Nature, 443, 2006
2HT8
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N8 NEURAMINIDASE IN COMPLEX WITH OSELTAMIVIR
分子名称:Neuraminidase, (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid
著者Russell, R.J., Haire, L.F., Stevens, D.J., Collins, P.J., Lin, Y.P., Blackburn, G.M., Hay, A.J., Gamblin, S.J., Skehel, J.J.
登録日2006-07-25
公開日2006-09-05
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design.
Nature, 443, 2006
2HTQ
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N8 NEURAMINIDASE IN COMPLEX WITH ZANAMIVIR
分子名称:Neuraminidase, ZANAMIVIR
著者Russell, R.J., Haire, L.F., Stevens, D.J., Collins, P.J., Lin, Y.P., Blackburn, G.M., Hay, A.J., Gamblin, S.J., Skehel, J.J.
登録日2006-07-26
公開日2006-09-05
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design.
Nature, 443, 2006
2HTR
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N8 NEURAMINIDASE IN COMPLEX WITH DANA
分子名称:Neuraminidase, 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID
著者Russell, R.J., Haire, L.F., Stevens, D.J., Collins, P.J., Lin, Y.P., Blackburn, G.M., Hay, A.J., Gamblin, S.J., Skehel, J.J.
登録日2006-07-26
公開日2006-09-05
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design.
Nature, 443, 2006
2HTU
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N8 NEURAMINIDASE IN COMPLEX WITH PERAMIVIR
分子名称:Neuraminidase, 3-(1-ACETYLAMINO-2-ETHYL-BUTYL)-4-GUANIDINO-2-HYDROXY-CYCLOPENTANECARBOXYLIC ACID
著者Russell, R.J., Haire, L.F., Stevens, D.J., Collins, P.J., Lin, Y.P., Blackburn, G.M., Hay, A.J., Gamblin, S.J., Skehel, J.J.
登録日2006-07-26
公開日2006-09-05
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design.
Nature, 443, 2006
2HTV
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N4 NEURAMINIDASE
分子名称:Neuraminidase, N-ACETYL-D-GLUCOSAMINE, CALCIUM ION
著者Russell, R.J., Haire, L.F., Stevens, D.J., Collins, P.J., Lin, Y.P., Blackburn, G.M., Hay, A.J., Gamblin, S.J., Skehel, J.J.
登録日2006-07-26
公開日2006-09-05
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design.
Nature, 443, 2006
2HTW
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N4 NEURAMINIDASE IN COMPLEX WITH DANA
分子名称:Neuraminidase, 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID
著者Russell, R.J., Haire, L.F., Stevens, D.J., Collins, P.J., Lin, Y.P., Blackburn, G.M., Hay, A.J., Gamblin, S.J., Skehel, J.J.
登録日2006-07-26
公開日2006-09-05
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design.
Nature, 443, 2006
2HTY
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N1 NEURAMINIDASE
分子名称:Neuraminidase, 2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE, CALCIUM ION, ...
著者Russell, R.J., Haire, L.F., Stevens, D.J., Collins, P.J., Lin, Y.P., Blackburn, G.M., Hay, A.J., Gamblin, S.J., Skehel, J.J.
登録日2006-07-26
公開日2006-09-05
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design.
Nature, 443, 2006
2HU0
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N1 NEURAMINIDASE IN COMPLEX WITH OSELTAMIVIR 1
分子名称:Neuraminidase, (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid
著者Russell, R.J., Haire, L.F., Stevens, D.J., Collins, P.J., Lin, Y.P., Blackburn, G.M., Hay, A.J., Gamblin, S.J., Skehel, J.J.
登録日2006-07-26
公開日2006-09-05
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design.
Nature, 443, 2006
2HU4
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N1 NEURAMINIDASE IN COMPLEX WITH OSELTAMIVIR 2
分子名称:Neuraminidase, (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid
著者Russell, R.J., Haire, L.F., Stevens, D.J., Collins, P.J., Lin, Y.P., Blackburn, G.M., Hay, A.J., Gamblin, S.J., Skehel, J.J.
登録日2006-07-26
公開日2006-09-05
最終更新日2018-02-14
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design.
Nature, 443, 2006
2IBX
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INFLUENZA VIRUS (VN1194) H5 HA
分子名称:Hemagglutinin, N-ACETYL-D-GLUCOSAMINE
著者Yamada, S., Russell, R.J., Gamblin, S.J., Skehel, J.J., Kawaoka, Y.
登録日2006-09-12
公開日2006-11-28
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Haemagglutinin mutations responsible for the binding of H5N1 influenza A viruses to human-type receptors.
Nature, 444, 2006
2V8Q
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CRYSTAL STRUCTURE OF THE REGULATORY FRAGMENT OF MAMMALIAN AMPK IN COMPLEXES WITH AMP
分子名称:5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-1, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT BETA-2, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT GAMMA-1, ...
著者Xiao, B., Heath, R., Saiu, P., Leiper, F.C., Leone, P., Jing, C., Walker, P.A., Haire, L., Eccleston, J.F., Davis, C.T., Martin, S.R., Carling, D., Gamblin, S.J.
登録日2007-08-13
公開日2007-09-25
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural Basis for AMP Binding to Mammalian AMP-Activated Protein Kinase
Nature, 449, 2007
2V92
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CRYSTAL STRUCTURE OF THE REGULATORY FRAGMENT OF MAMMALIAN AMPK IN COMPLEXES WITH ATP-AMP
分子名称:5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-1, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT BETA-2, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT GAMMA-1, ...
著者Xiao, B., Heath, R., Saiu, P., Leiper, F.C., Leone, P., Jing, C., Walker, P.A., Haire, L., Eccleston, J.F., Davis, C.T., Martin, S.R., Carling, D., Gamblin, S.J.
登録日2007-08-20
公開日2007-09-25
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural Basis for AMP Binding to Mammalian AMP-Activated Protein Kinase
Nature, 449, 2007
2V9J
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CRYSTAL STRUCTURE OF THE REGULATORY FRAGMENT OF MAMMALIAN AMPK IN COMPLEXES WITH MG.ATP-AMP
分子名称:5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-1, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT BETA-2, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT GAMMA-1, ...
著者Xiao, B., Heath, R., Saiu, P., Leiper, F.C., Leone, P., Jing, C., Walker, P.A., Haire, L., Eccleston, J.F., Davis, C.T., Martin, S.R., Carling, D., Gamblin, S.J.
登録日2007-08-23
公開日2007-09-25
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.53 Å)
主引用文献Structural Basis for AMP Binding to Mammalian AMP-Activated Protein Kinase
Nature, 449, 2007
2WR1
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STRUCTURE OF INFLUENZA H2 HEMAGGLUTININ WITH HUMAN RECEPTOR
分子名称:HEMAGGLUTININ, N-ACETYL-D-GLUCOSAMINE, O-SIALIC ACID, ...
著者Liu, J., Stevens, D.J., Haire, L.F., Walker, P.A., Coombs, P.J., Russell, R.J., Gamblin, S.J., Skehel, J.J.
登録日2009-08-29
公開日2009-09-29
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献From the Cover: Structures of Receptor Complexes Formed by Hemagglutinins from the Asian Influenza Pandemic of 1957.
Proc.Natl.Acad.Sci.USA, 106, 2009