Author results

3FX4
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PORCINE ALDEHYDE REDUCTASE IN TERNARY COMPLEX WITH INHIBITOR
Descriptor:Alcohol dehydrogenase [NADP+], SULFATE ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Carbone, V., El-Kabbani, O.
Deposit date:2009-01-20
Release date:2009-12-22
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Structure of Aldehyde Reductase in Ternary Complex with a 5-Arylidene-2,4-thiazolidinedione Aldose Reductase Inhibitor
To be Published
3GUG
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CRYSTAL STRUCTURE OF AKR1C1 L308V MUTANT IN COMPLEX WITH NADP AND 3,5-DICHLOROSALICYLIC ACID
Descriptor:Aldo-keto reductase family 1 member C1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 3,5-dichloro-2-hydroxybenzoic acid, ...
Authors:Dhagat, U., El-Kabbani, O.
Deposit date:2009-03-30
Release date:2010-02-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of AKR1C1 L308V mutant in complex with NADP and 3,5-dichlorosalicylic acid
To be Published
3O3R
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CRYSTAL STRUCTURE OF AKR1B14 IN COMPLEX WITH NADP
Descriptor:Aldo-keto reductase family 1, member B7, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Sundaram, K., Dhagat, U., El-Kabbani, O.
Deposit date:2010-07-26
Release date:2011-01-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Structure of rat aldose reductase-like protein AKR1B14 holoenzyme: Probing the role of His269 in coenzyme binding by site-directed mutagenesis
Bioorg.Med.Chem.Lett., 21, 2011
3OHS
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CRYSTAL STRUCTURE OF MAMMALIAN DIMERIC DIHYDRODIOL DEHYDROGENASE IN COMPLEX WITH DIHYDROXYACETONE
Descriptor:Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase, SULFATE ION, BETA-MERCAPTOETHANOL, ...
Authors:Zhao, H.-T., El-Kabbani, O.
Deposit date:2010-08-18
Release date:2011-08-24
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of MDD in complex with Dihydroxyacetone
To be Published
3QKZ
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CRYSTAL STRUCTURE OF MUTANT HIS269ARG AKR1B14
Descriptor:Aldo-keto reductase family 1, member B7, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Sundaram, K., El-Kabbani, O.
Deposit date:2011-02-02
Release date:2012-02-29
Last modified:2012-05-02
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Structure of the His269Arg mutant of the rat aldose reductase-like protein AKR1B14 complexed with NADPH.
Acta Crystallogr.,Sect.F, 68, 2012
1DSU
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HUMAN FACTOR D, COMPLEMENT ACTIVATING ENZYME
Descriptor:FACTOR D
Authors:Narayana, S.V.L., Volanakis, J.E., Delucas, L.J.
Deposit date:1995-09-15
Release date:1996-08-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of human factor D. A complement system protein at 2.0 A resolution.
J.Mol.Biol., 235, 1994
2RCR
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STRUCTURE OF THE MEMBRANE-BOUND PROTEIN PHOTOSYNTHETIC REACTION CENTER FROM RHODOBACTER SPHAEROIDES
Descriptor:PHOTOSYNTHETIC REACTION CENTER (L SUBUNIT), PHOTOSYNTHETIC REACTION CENTER (M SUBUNIT), PHOTOSYNTHETIC REACTION CENTER (H SUBUNIT), ...
Authors:Chang, C.-H., Norris, J., Schiffer, M.
Deposit date:1991-02-04
Release date:1993-07-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structure of the membrane-bound protein photosynthetic reaction center from Rhodobacter sphaeroides.
Biochemistry, 30, 1991
1BIO
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HUMAN COMPLEMENT FACTOR D IN COMPLEX WITH ISATOIC ANHYDRIDE INHIBITOR
Descriptor:COMPLEMENT FACTOR D, ISATOIC ANHYDRIDE, GLYCEROL
Authors:Jing, H., Babu, Y.S., Moore, D., Kilpatrick, J.M., Liu, X.-Y., Volanakis, J.E., Narayana, S.V.L.
Deposit date:1998-06-18
Release date:1999-06-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structures of native and complexed complement factor D: implications of the atypical His57 conformation and self-inhibitory loop in the regulation of specific serine protease activity.
J.Mol.Biol., 282, 1998
1C3I
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HUMAN STROMELYSIN-1 CATALYTIC DOMAIN COMPLEXED WITH RO-26-2812
Descriptor:STROMELYSIN-1, ZINC ION, CALCIUM ION, ...
Authors:Steele, D.L., Kammlott, R.U., Crowther, R.L., Birktoft, J.J., Dunten, P., Engler, J.E.
Deposit date:1999-07-27
Release date:2000-07-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Expression, characterization and structure determination of an active site mutant (Glu202-Gln) of mini-stromelysin-1.
Protein Eng., 13, 2000
1DST
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MUTANT OF FACTOR D WITH ENHANCED CATALYTIC ACTIVITY
Descriptor:FACTOR D
Authors:Narayana, S.V.L., Volanakis, J.E.
Deposit date:1995-09-13
Release date:1996-07-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of a complement factor D mutant expressing enhanced catalytic activity.
J.Biol.Chem., 270, 1995
1HFD
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HUMAN COMPLEMENT FACTOR D IN A P21 CRYSTAL FORM
Descriptor:COMPLEMENT FACTOR D
Authors:Jing, H., Babu, Y.S., Moore, D., Kilpatrick, J.M., Liu, X.-Y., Volanakis, J.E., Narayana, S.V.L.
Deposit date:1998-06-18
Release date:1999-06-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structures of native and complexed complement factor D: implications of the atypical His57 conformation and self-inhibitory loop in the regulation of specific serine protease activity.
J.Mol.Biol., 282, 1998
2OKJ
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THE X-RAY CRYSTAL STRUCTURE OF THE 67KDA ISOFORM OF GLUTAMIC ACID DECARBOXYLASE (GAD67)
Descriptor:Glutamate decarboxylase 1, GAMMA-AMINO-BUTANOIC ACID, 4-[({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)AMINO]BUTANOIC ACID
Authors:Buckle, A.M., Fenalti, G., Law, R.H.P., Whisstock, J.C.
Deposit date:2007-01-17
Release date:2007-03-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:GABA production by glutamic acid decarboxylase is regulated by a dynamic catalytic loop.
Nat.Struct.Mol.Biol., 14, 2007
2OKK
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THE X-RAY CRYSTAL STRUCTURE OF THE 65KDA ISOFORM OF GLUTAMIC ACID DECARBOXYLASE (GAD65)
Descriptor:Glutamate decarboxylase 2, GAMMA-AMINO-BUTANOIC ACID, GLYCEROL
Authors:Buckle, A.M., Fenalti, G., Law, R.H.P., Whisstock, J.C.
Deposit date:2007-01-17
Release date:2007-03-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:GABA production by glutamic acid decarboxylase is regulated by a dynamic catalytic loop.
Nat.Struct.Mol.Biol., 14, 2007
1FDP
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PROENZYME OF HUMAN COMPLEMENT FACTOR D, RECOMBINANT PROFACTOR D
Descriptor:PROENZYME OF COMPLEMENT FACTOR D
Authors:Jing, H., Macon, K.J., Moore, D., Delucas, L.J., Volanakis, J.E., Narayana, S.V.L.
Deposit date:1998-12-03
Release date:1999-12-03
Last modified:2011-12-07
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis of profactor D activation: from a highly flexible zymogen to a novel self-inhibited serine protease, complement factor D.
Embo J., 18, 1999
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