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8AE2
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BU of 8ae2 by Molmil
Cryo-EM structure of full-length human immunoglobulin M - F(ab')2 conformation 5
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, IgM C2-domain from mouse, ...
Authors:Chen, Q, Rosenthal, P, Tolar, P.
Deposit date:2022-07-12
Release date:2022-10-26
Last modified:2022-11-09
Method:ELECTRON MICROSCOPY (8.5 Å)
Cite:Cryomicroscopy reveals the structural basis for a flexible hinge motion in the immunoglobulin M pentamer.
Nat Commun, 13, 2022
8ADZ
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BU of 8adz by Molmil
Cryo-EM structure of full-length human immunoglobulin M - F(ab')2 conformation 2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, IgM C2-domain from mouse, ...
Authors:Chen, Q, Rosenthal, P, Tolar, P.
Deposit date:2022-07-12
Release date:2022-10-26
Last modified:2022-11-09
Method:ELECTRON MICROSCOPY (6.7 Å)
Cite:Cryomicroscopy reveals the structural basis for a flexible hinge motion in the immunoglobulin M pentamer.
Nat Commun, 13, 2022
8AE0
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BU of 8ae0 by Molmil
Cryo-EM structure of full-length human immunoglobulin M - F(ab')2 conformation 3
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, IgM C2-domain from mouse, ...
Authors:Chen, Q, Rosenthal, P, Tolar, P.
Deposit date:2022-07-12
Release date:2022-10-26
Last modified:2022-11-09
Method:ELECTRON MICROSCOPY (7.1 Å)
Cite:Cryomicroscopy reveals the structural basis for a flexible hinge motion in the immunoglobulin M pentamer.
Nat Commun, 13, 2022
8AE3
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BU of 8ae3 by Molmil
Cryo-EM structure of full-length human immunoglobulin M - F(ab')2 conformation 4
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, IgM C2-domain from mouse, ...
Authors:Chen, Q, Rosenthal, P, Tolar, P.
Deposit date:2022-07-12
Release date:2022-10-26
Last modified:2022-11-09
Method:ELECTRON MICROSCOPY (6.8 Å)
Cite:Cryomicroscopy reveals the structural basis for a flexible hinge motion in the immunoglobulin M pentamer.
Nat Commun, 13, 2022
8ADY
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BU of 8ady by Molmil
Cryo-EM structure of full-length human immunoglobulin M - F(ab')2 conformation 1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, IgM C2-domain from mouse, ...
Authors:Chen, Q, Rosenthal, P, Tolar, P.
Deposit date:2022-07-12
Release date:2022-10-26
Last modified:2022-11-09
Method:ELECTRON MICROSCOPY (5.2 Å)
Cite:Cryomicroscopy reveals the structural basis for a flexible hinge motion in the immunoglobulin M pentamer.
Nat Commun, 13, 2022
7QDO
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BU of 7qdo by Molmil
Cryo-EM structure of human monomeric IgM-Fc
Descriptor: Isoform 2 of Immunoglobulin heavy constant mu
Authors:Chen, Q, Rosenthal, P, Tolar, P.
Deposit date:2021-11-27
Release date:2022-10-26
Last modified:2022-11-09
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Cryomicroscopy reveals the structural basis for a flexible hinge motion in the immunoglobulin M pentamer.
Nat Commun, 13, 2022
6X68
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BU of 6x68 by Molmil
Cryo-EM structure of piggyBac transposase synaptic complex with hairpin DNA (SNHP)
Descriptor: CALCIUM ION, Transposase, ZINC ION, ...
Authors:Chen, Q, Hickman, A.B, Dyda, F.
Deposit date:2020-05-27
Release date:2020-07-22
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.66 Å)
Cite:Structural basis of seamless excision and specific targeting by piggyBac transposase
Nat Commun, 11, 2020
6X67
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BU of 6x67 by Molmil
Cryo-EM structure of piggyBac transposase strand transfer complex (STC)
Descriptor: CALCIUM ION, DNA (37-MER), DNA (47-MER), ...
Authors:Chen, Q, Hickman, A.B, Dyda, F.
Deposit date:2020-05-27
Release date:2020-07-22
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.47 Å)
Cite:Structural basis of seamless excision and specific targeting by piggyBac transposase
Nat Commun, 11, 2020
2AIN
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BU of 2ain by Molmil
Solution structure of the AF-6 PDZ domain complexed with the C-terminal peptide from the Bcr protein
Descriptor: 6-mer peptide from Breakpoint cluster region protein, Afadin
Authors:Chen, Q, Wu, J, Shi, Y.
Deposit date:2005-07-30
Release date:2006-07-18
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:Solution structure and backbone dynamics of the AF-6 PDZ domain/Bcr peptide complex.
Protein Sci., 16, 2007
7MTB
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BU of 7mtb by Molmil
Rhodopsin kinase (GRK1)-S5E/S488E/T489E in complex with rhodopsin and Fab6
Descriptor: Fab6 heavy chain, Fab6 light chain, RETINAL, ...
Authors:Chen, Q, Chen, C.-L, Tesmer, J.J.G.
Deposit date:2021-05-13
Release date:2021-07-07
Last modified:2021-08-25
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structures of rhodopsin in complex with G-protein-coupled receptor kinase 1.
Nature, 595, 2021
7MT8
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BU of 7mt8 by Molmil
Rhodopsin kinase (GRK1)-S5E/S488E/T489E in complex with rhodopsin
Descriptor: RETINAL, Rhodopsin, Rhodopsin kinase GRK1, ...
Authors:Chen, Q, Chen, C.-L, Tesmer, J.J.G.
Deposit date:2021-05-13
Release date:2021-07-07
Last modified:2021-08-25
Method:ELECTRON MICROSCOPY (5.8 Å)
Cite:Structures of rhodopsin in complex with G-protein-coupled receptor kinase 1.
Nature, 595, 2021
7MTA
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BU of 7mta by Molmil
Rhodopsin kinase (GRK1)-S5E/S488E/T489E in complex with rhodopsin and Fab1
Descriptor: Fab1 Heavy chain, Fab1 Light chain, RETINAL, ...
Authors:Chen, Q, Chen, C.-L, Tesmer, J.J.G.
Deposit date:2021-05-13
Release date:2021-07-07
Last modified:2021-08-25
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structures of rhodopsin in complex with G-protein-coupled receptor kinase 1.
Nature, 595, 2021
7MT9
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BU of 7mt9 by Molmil
Rhodopsin kinase (GRK1) in complex with rhodopsin
Descriptor: RETINAL, Rhodopsin, Rhodopsin kinase GRK1, ...
Authors:Chen, Q, Chen, C.-L, Tesmer, J.J.G.
Deposit date:2021-05-13
Release date:2021-07-07
Last modified:2021-08-25
Method:ELECTRON MICROSCOPY (7 Å)
Cite:Structures of rhodopsin in complex with G-protein-coupled receptor kinase 1.
Nature, 595, 2021
1YFZ
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BU of 1yfz by Molmil
Novel IMP Binding in Feedback Inhibition of Hypoxanthine-Guanine Phosphoribosyltransferase from Thermoanaerobacter tengcongensis
Descriptor: ACETATE ION, Hypoxanthine-guanine phosphoribosyltransferase, INOSINIC ACID, ...
Authors:Chen, Q, Liang, Y, Su, X, Gu, X, Zheng, X, Luo, M.
Deposit date:2005-01-04
Release date:2005-05-10
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Alternative IMP Binding in Feedback Inhibition of Hypoxanthine-Guanine Phosphoribosyltransferase from Thermoanaerobacter tengcongensis.
J.Mol.Biol., 348, 2005
8BPF
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BU of 8bpf by Molmil
FcMR binding at subunit Fcu1 of IgM pentamer
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fas apoptotic inhibitory molecule 3, ...
Authors:Chen, Q, Rosenthal, P, Tolar, P.
Deposit date:2022-11-16
Release date:2023-04-12
Last modified:2023-07-26
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural basis for Fc receptor recognition of immunoglobulin M.
Nat.Struct.Mol.Biol., 30, 2023
8BPG
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BU of 8bpg by Molmil
FcMR binding at subunit Fcu3 of IgM pentamer
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fas apoptotic inhibitory molecule 3, ...
Authors:Chen, Q, Rosenthal, P, Tolar, P.
Deposit date:2022-11-16
Release date:2023-04-12
Last modified:2023-07-26
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural basis for Fc receptor recognition of immunoglobulin M.
Nat.Struct.Mol.Biol., 30, 2023
8BPE
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BU of 8bpe by Molmil
8:1 binding of FcMR on IgM pentameric core
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fas apoptotic inhibitory molecule 3, ...
Authors:Chen, Q, Rosenthal, P, Tolar, P.
Deposit date:2022-11-16
Release date:2023-04-12
Last modified:2023-07-26
Method:ELECTRON MICROSCOPY (3.63 Å)
Cite:Structural basis for Fc receptor recognition of immunoglobulin M.
Nat.Struct.Mol.Biol., 30, 2023
1R3U
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BU of 1r3u by Molmil
Crystal Structure of Hypoxanthine-Guanine Phosphoribosyltransferase from Thermoanaerobacter tengcongensis
Descriptor: ACETATE ION, Hypoxanthine-guanine phosphoribosyltransferase, MAGNESIUM ION
Authors:Chen, Q, Liang, Y.H, Gu, X.C, Luo, M, Su, X.D.
Deposit date:2003-10-03
Release date:2004-10-19
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structure of Hypoxanthine-Guanine Phosphoribosyltransferase from Thermoanaerobacter tengcongensis
To be published
4Z90
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BU of 4z90 by Molmil
ELIC bound with the anesthetic isoflurane in the resting state
Descriptor: (2R)-2-chloro-2-(difluoromethoxy)-1,1,1-trifluoroethane, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Gamma-aminobutyric-acid receptor subunit beta-1
Authors:Chen, Q, Kinde, M, Arjunan, P, Cohen, A, Xu, Y, Tang, P.
Deposit date:2015-04-09
Release date:2015-09-16
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3 Å)
Cite:Direct Pore Binding as a Mechanism for Isoflurane Inhibition of the Pentameric Ligand-gated Ion Channel ELIC.
Sci Rep, 5, 2015
4Z91
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BU of 4z91 by Molmil
ELIC cocrystallized with isofluorane in a desensitized state
Descriptor: (2R)-2-chloro-2-(difluoromethoxy)-1,1,1-trifluoroethane, 1.7.6 3-bromanylpropan-1-amine, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ...
Authors:Chen, Q, Kinde, M.N, Arjunan, P, Cohen, A, Xu, Y, Tang, P.
Deposit date:2015-04-09
Release date:2015-09-16
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.3915 Å)
Cite:Direct Pore Binding as a Mechanism for Isoflurane Inhibition of the Pentameric Ligand-gated Ion Channel ELIC.
Sci Rep, 5, 2015
7S03
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BU of 7s03 by Molmil
DNA-binding domain of human SETMAR in complex with Hsmar1 terminal inverted repeat (TIR) DNA
Descriptor: Histone-lysine N-methyltransferase SETMAR, Hsmar1 terminal inverted repeats
Authors:Chen, Q, Georgiadis, M.M.
Deposit date:2021-08-28
Release date:2022-08-03
Method:X-RAY DIFFRACTION (2.37 Å)
Cite:Structural and genome-wide analyses suggest that transposon-derived protein SETMAR alters transcription and splicing.
J.Biol.Chem., 298, 2022
5SXU
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BU of 5sxu by Molmil
X-ray structure of 2-bromoethanol bound to a pentameric ligand gated ion channel (ELIC) in a desensitized state
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-BROMOETHANOL, 3-AMINOPROPANE, ...
Authors:Chen, Q, Kinde, M, Cohen, A, Xu, Y, Tang, P.
Deposit date:2016-08-10
Release date:2017-06-21
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural Basis of Alcohol Inhibition of the Pentameric Ligand-Gated Ion Channel ELIC.
Structure, 25, 2017
5SXV
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BU of 5sxv by Molmil
X-ray structure of 2-bromoethanol bound to a pentameric ligand gated ion channel (ELIC) in a resting state
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-BROMOETHANOL, Cys-loop ligand-gated ion channel
Authors:Chen, Q, Kinde, M, Cohen, A, Xu, Y, Tang, P.
Deposit date:2016-08-10
Release date:2017-06-21
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structural Basis of Alcohol Inhibition of the Pentameric Ligand-Gated Ion Channel ELIC.
Structure, 25, 2017
5TV1
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BU of 5tv1 by Molmil
active arrestin-3 with inositol hexakisphosphate
Descriptor: Beta-arrestin-2, GLYCEROL, INOSITOL HEXAKISPHOSPHATE
Authors:Chen, Q, Gilbert, N.C, Perry, N.A, Vishniveteskiy, S, Gurevich, V.V, Iverson, T.M.
Deposit date:2016-11-07
Release date:2017-11-22
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis of arrestin-3 activation and signaling.
Nat Commun, 8, 2017
5WPT
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BU of 5wpt by Molmil
Cryo-EM structure of mammalian endolysosomal TRPML1 channel in nanodiscs in closed II conformation at 3.75 Angstrom resolution
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Mucolipin-1, SODIUM ION
Authors:Chen, Q, She, J, Guo, J, Bai, X, Jiang, Y.
Deposit date:2017-08-07
Release date:2017-10-18
Last modified:2023-04-05
Method:ELECTRON MICROSCOPY (3.75 Å)
Cite:Structure of mammalian endolysosomal TRPML1 channel in nanodiscs.
Nature, 550, 2017

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PDB entries from 2024-03-27

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