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157L
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CONTROL OF ENZYME ACTIVITY BY AN ENGINEERED DISULFIDE BOND
Descriptor:T4 LYSOZYME, CHLORIDE ION, BETA-MERCAPTOETHANOL
Authors:Blaber, M., Matthews, B.W.
Deposit date:1994-06-20
Release date:1994-08-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Alanine scanning mutagenesis of the alpha-helix 115-123 of phage T4 lysozyme: effects on structure, stability and the binding of solvent.
J.Mol.Biol., 246, 1995
158L
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CONTROL OF ENZYME ACTIVITY BY AN ENGINEERED DISULFIDE BOND
Descriptor:T4 LYSOZYME, CHLORIDE ION, BETA-MERCAPTOETHANOL
Authors:Blaber, M., Matthews, B.W.
Deposit date:1994-06-20
Release date:1994-08-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Alanine scanning mutagenesis of the alpha-helix 115-123 of phage T4 lysozyme: effects on structure, stability and the binding of solvent.
J.Mol.Biol., 246, 1995
159L
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CONTROL OF ENZYME ACTIVITY BY AN ENGINEERED DISULFIDE BOND
Descriptor:T4 LYSOZYME, CHLORIDE ION, BETA-MERCAPTOETHANOL
Authors:Blaber, M., Matthews, B.W.
Deposit date:1994-06-20
Release date:1994-08-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Alanine scanning mutagenesis of the alpha-helix 115-123 of phage T4 lysozyme: effects on structure, stability and the binding of solvent.
J.Mol.Biol., 246, 1995
160L
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CONTROL OF ENZYME ACTIVITY BY AN ENGINEERED DISULFIDE BOND
Descriptor:T4 LYSOZYME, CHLORIDE ION, BETA-MERCAPTOETHANOL
Authors:Blaber, M., Matthews, B.W.
Deposit date:1994-06-20
Release date:1994-08-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Alanine scanning mutagenesis of the alpha-helix 115-123 of phage T4 lysozyme: effects on structure, stability and the binding of solvent.
J.Mol.Biol., 246, 1995
161L
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CONTROL OF ENZYME ACTIVITY BY AN ENGINEERED DISULFIDE BOND
Descriptor:T4 LYSOZYME, CHLORIDE ION, BETA-MERCAPTOETHANOL
Authors:Blaber, M., Matthews, B.W.
Deposit date:1994-06-20
Release date:1994-08-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Alanine scanning mutagenesis of the alpha-helix 115-123 of phage T4 lysozyme: effects on structure, stability and the binding of solvent.
J.Mol.Biol., 246, 1995
162L
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CONTROL OF ENZYME ACTIVITY BY AN ENGINEERED DISULFIDE BOND
Descriptor:T4 LYSOZYME, CHLORIDE ION, BETA-MERCAPTOETHANOL
Authors:Blaber, M., Matthews, B.W.
Deposit date:1994-06-20
Release date:1994-08-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Alanine scanning mutagenesis of the alpha-helix 115-123 of phage T4 lysozyme: effects on structure, stability and the binding of solvent.
J.Mol.Biol., 246, 1995
163L
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CONTROL OF ENZYME ACTIVITY BY AN ENGINEERED DISULFIDE BOND
Descriptor:T4 LYSOZYME, CHLORIDE ION, BETA-MERCAPTOETHANOL
Authors:Blaber, M., Matthews, B.W.
Deposit date:1994-06-20
Release date:1994-08-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Alanine scanning mutagenesis of the alpha-helix 115-123 of phage T4 lysozyme: effects on structure, stability and the binding of solvent.
J.Mol.Biol., 246, 1995
164L
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CONTROL OF ENZYME ACTIVITY BY AN ENGINEERED DISULFIDE BOND
Descriptor:T4 LYSOZYME, CHLORIDE ION, BETA-MERCAPTOETHANOL
Authors:Blaber, M., Matthews, B.W.
Deposit date:1994-06-20
Release date:1994-08-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Alanine scanning mutagenesis of the alpha-helix 115-123 of phage T4 lysozyme: effects on structure, stability and the binding of solvent.
J.Mol.Biol., 246, 1995
165L
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CONTROL OF ENZYME ACTIVITY BY AN ENGINEERED DISULFIDE BOND
Descriptor:T4 LYSOZYME, CHLORIDE ION, BETA-MERCAPTOETHANOL
Authors:Blaber, M., Matthews, B.W.
Deposit date:1994-06-20
Release date:1994-08-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Alanine scanning mutagenesis of the alpha-helix 115-123 of phage T4 lysozyme: effects on structure, stability and the binding of solvent.
J.Mol.Biol., 246, 1995
166L
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CONTROL OF ENZYME ACTIVITY BY AN ENGINEERED DISULFIDE BOND
Descriptor:T4 LYSOZYME, CHLORIDE ION, BETA-MERCAPTOETHANOL
Authors:Blaber, M., Matthews, B.W.
Deposit date:1994-06-20
Release date:1994-08-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Alanine scanning mutagenesis of the alpha-helix 115-123 of phage T4 lysozyme: effects on structure, stability and the binding of solvent.
J.Mol.Biol., 246, 1995
206L
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PHAGE T4 LYSOZYME
Descriptor:LYSOZYME, CHLORIDE ION, BETA-MERCAPTOETHANOL
Authors:Blaber, M., Matthews, B.W.
Deposit date:1996-03-19
Release date:1996-08-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Energetic cost and structural consequences of burying a hydroxyl group within the core of a protein determined from Ala-->Ser and Val-->Thr substitutions in T4 lysozyme.
Biochemistry, 32, 1993
2AFG
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2.0 ANGSTROM X-RAY STRUCTURE OF HUMAN ACIDIC FIBROBLAST GROWTH FACTOR
Descriptor:ACIDIC FIBROBLAST GROWTH FACTOR, SULFATE ION
Authors:Blaber, M., Disalvo, J., Thomas, K.A.
Deposit date:1995-07-21
Release date:1995-10-15
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:X-ray crystal structure of human acidic fibroblast growth factor.
Biochemistry, 35, 1996
3L64
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T4 LYSOZYME S44E/WT*
Descriptor:Lysozyme, BETA-MERCAPTOETHANOL
Authors:Blaber, M., Zhang, X.-J., Lindstrom, J.D., Pepiot, S.D., Baase, W.A., Matthews, B.W.
Deposit date:2009-12-23
Release date:2010-01-19
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Determination of alpha-helix propensity within the context of a folded protein. Sites 44 and 131 in bacteriophage T4 lysozyme.
J.Mol.Biol., 235, 1994
3P6I
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CRYSTAL STRUCTURE OF SYMFOIL-4T PERMUTATION #2: DE NOVO DESIGNED BETA-TREFOIL ARCHITECTURE WITH SYMMETRIC PRIMARY STRUCTURE
Descriptor:de novo designed beta-trefoil architecture with symmetric primary structure, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, SULFATE ION
Authors:Blaber, M., Lee, J.
Deposit date:2010-10-11
Release date:2011-10-12
Method:X-RAY DIFFRACTION (1.32 Å)
Cite:Permutations study of de novo designed symmetric beta-trefoil architecture
To be Published
3P6J
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CRYSTAL STRUCTURE OF SYMFOIL-4T PERMUTATION #3: DE NOVO DESIGNED BETA-TREFOIL ARCHITECTURE WITH SYMMETRIC PRIMARY STRUCTURE
Descriptor:de novo designed beta-trefoil architecture with symmetric primary structure
Authors:Blaber, M., Lee, J.
Deposit date:2010-10-11
Release date:2011-10-12
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Permutations study of de novo designed symmetric beta-trefoil architecture
To be Published
4F34
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SYMFOIL-4V SYNTHETIC PROTEIN WITH T30E/T72E/T116E MUTATIONS, AND DELTA HIS TAG
Descriptor:de novo protein Symfoil-4V
Authors:Blaber, M., Xia, X.
Deposit date:2012-05-08
Release date:2013-05-08
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Symfoil-4V synthetic protein with T30E/T72E/T116E mutations, and delta His tag
TO BE PUBLISHED
4QO3
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CRYSTAL STRUCTURE OF C16S/N18S/K12V/C117V/P134V MUTANT OF HUMAN ACIDIC FIBROBLAST GROWTH FACTOR
Descriptor:Fibroblast growth factor 1, CITRATE ANION, IMIDAZOLE
Authors:Blaber, M., Xia, X.
Deposit date:2014-06-19
Release date:2015-05-06
Method:X-RAY DIFFRACTION (2.047 Å)
Cite:Thermodynamics of Cysteine Substitution Suggest Unique Structural Role for Cysteine in Proteins
To be Published
3HAL
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CRYSTAL STRUCTURE OF RABBIT ACIDIC FIBROBLAST GROWTH FACTOR
Descriptor:Fibroblast growth factor 1 isoform 1, SULFATE ION, CHLORIDE ION
Authors:Blaber, M., Lee, J.
Deposit date:2009-05-01
Release date:2009-12-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:X-ray structure and biophysical properties of rabbit fibroblast growth factor 1.
Acta Crystallogr.,Sect.F, 65, 2009
3B9U
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CRYSTAL STRUCTURE OF L26N/D28N/H93G MUTANT OF HUMAN ACIDIC FIBROBLAST GROWTH FACTOR
Descriptor:Heparin-binding growth factor 1, SULFATE ION
Authors:Blaber, M., Lee, J.
Deposit date:2007-11-06
Release date:2008-04-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:A logical OR redundancy within the Asx-Pro-Asx-Gly type I beta-turn motif.
J.Mol.Biol., 377, 2008
3BA4
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CRYSTAL STRUCTURE OF L26D MUTANT OF HUMAN ACIDIC FIBROBLAST GROWTH FACTOR
Descriptor:Heparin-binding growth factor 1, SULFATE ION, FORMIC ACID
Authors:Blaber, M., Lee, J.
Deposit date:2007-11-07
Release date:2008-04-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A logical OR redundancy within the Asx-Pro-Asx-Gly type I beta-turn motif.
J.Mol.Biol., 377, 2008
3BA5
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CRYSTAL STRUCTURE OF D28A MUTANT OF HUMAN ACIDIC FIBROBLAST GROWTH FACTOR
Descriptor:Heparin-binding growth factor 1, SULFATE ION, FORMIC ACID
Authors:Blaber, M., Lee, J.
Deposit date:2007-11-07
Release date:2008-04-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:A logical OR redundancy within the Asx-Pro-Asx-Gly type I beta-turn motif.
J.Mol.Biol., 377, 2008
3BA7
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CRYSTAL STRUCTURE OF L26N/D28A MUTANT OF HUMAN ACIDIC FIBROBLAST GROWTH FACTOR
Descriptor:Heparin-binding growth factor 1, SULFATE ION, FORMIC ACID
Authors:Blaber, M., Lee, J.
Deposit date:2007-11-07
Release date:2008-04-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:A logical OR redundancy within the Asx-Pro-Asx-Gly type I beta-turn motif.
J.Mol.Biol., 377, 2008
3BAD
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CRYSTAL STRUCTURE OF D70A/H93G MUTANT OF HUMAN ACIDIC FIBROBLAST GROWTH FACTOR
Descriptor:Heparin-binding growth factor 1, SULFATE ION
Authors:Blaber, M., Lee, J.
Deposit date:2007-11-07
Release date:2008-04-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:A logical OR redundancy within the Asx-Pro-Asx-Gly type I beta-turn motif.
J.Mol.Biol., 377, 2008
3FGM
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CRYSTAL STRUCTURE OF L44F/C83T/C117V/F132W MUTANT OF HUMAN ACIDIC FIBROBLAST GROWTH FACTOR
Descriptor:Heparin-binding growth factor 1, SULFATE ION, FORMIC ACID
Authors:Blaber, M., Lee, J.
Deposit date:2008-12-06
Release date:2009-10-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:The interaction between thermodynamic stability and buried free cysteines in regulating the functional half-life of fibroblast growth factor-1.
J.Mol.Biol., 393, 2009
3FJ8
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CRYSTAL STRUCTURE OF C117I MUTANT OF HUMAN ACIDIC FIBROBLAST GROWTH FACTOR
Descriptor:Heparin-binding growth factor 1, SULFATE ION
Authors:Blaber, M., Lee, J.
Deposit date:2008-12-14
Release date:2009-10-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:The interaction between thermodynamic stability and buried free cysteines in regulating the functional half-life of fibroblast growth factor-1.
J.Mol.Biol., 393, 2009