4PWX
 
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1A32
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2AX4
 | | Crystal structure of the kinase domain of human 3'-phosphoadenosine 5'-phosphosulphate synthetase 2 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthetase 2 | | Authors: | Rabeh, W.M, Nedyalkova, L, Ismail, S, Park, H, Arrowsmith, C, Edwards, A, Sundstrom, M, Weigelt, J, Bochkarev, A, Structural Genomics Consortium (SGC) | | Deposit date: | 2005-09-02 | | Release date: | 2005-09-20 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal structure of the kinase domain of PAPSS 2
To be Published
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5NRF
 | | Crystal structure of human chitotriosidase-1 (hCHIT) catalytic domain in complex with compound 7i | | Descriptor: | 1-(3-azanyl-1~{H}-1,2,4-triazol-5-yl)-~{N}-[2-(4-chlorophenyl)ethyl]-~{N}-(phenylmethyl)piperidin-4-amine, Chitotriosidase-1, GLYCEROL | | Authors: | Mazur, M, Olczak, J, Olejniczak, S, Koralewski, R, Czestkowski, W, Jedrzejczak, A, Golab, J, Dzwonek, K, Dymek, B, Sklepkiewicz, P, Zagozdzon, A, Noonan, T, Mahboubi, K, Conway, B, Sheeler, R, Beckett, P, Hungerford, W.M, Podjarny, A, Mitschler, A, Cousido-Siah, A, Fadel, F, Golebiowski, A. | | Deposit date: | 2017-04-22 | | Release date: | 2018-03-28 | | Method: | X-RAY DIFFRACTION (1.447 Å) | | Cite: | Targeting Acidic Mammalian chitinase Is Effective in Animal Model of Asthma.
J. Med. Chem., 61, 2018
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1B3B
 | | THERMOTOGA MARITIMA GLUTAMATE DEHYDROGENASE MUTANT N97D, G376K | | Descriptor: | PROTEIN (GLUTAMATE DEHYDROGENASE) | | Authors: | Knapp, S, Lebbink, J.H.G, Van Der Oost, J, Devos, W.M, Rice, D, Ladenstein, R. | | Deposit date: | 1998-12-07 | | Release date: | 1999-12-08 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Engineering activity and stability of Thermotoga maritima glutamate dehydrogenase. I. Introduction of a six-residue ion-pair network in the hinge region.
J.Mol.Biol., 280, 1998
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1B26
 | | GLUTAMATE DEHYDROGENASE | | Descriptor: | GLUTAMATE DEHYDROGENASE | | Authors: | Knapp, S, Devos, W.M, Rice, D, Ladenstein, R. | | Deposit date: | 1998-12-04 | | Release date: | 1999-12-03 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Crystal structure of glutamate dehydrogenase from the hyperthermophilic eubacterium Thermotoga maritima at 3.0 A resolution.
J.Mol.Biol., 267, 1997
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1BRV
 | | SOLUTION NMR STRUCTURE OF THE IMMUNODOMINANT REGION OF PROTEIN G OF BOVINE RESPIRATORY SYNCYTIAL VIRUS, 48 STRUCTURES | | Descriptor: | PROTEIN G | | Authors: | Doreleijers, J.F, Langedijk, J.P.M, Hard, K, Rullmann, J.A.C, Boelens, R, Schaaper, W.M, Van Oirschot, J.T, Kaptein, R. | | Deposit date: | 1996-03-29 | | Release date: | 1997-06-05 | | Last modified: | 2017-11-29 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the immunodominant region of protein G of bovine respiratory syncytial virus.
Biochemistry, 35, 1996
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5NRA
 | | Crystal structure of human chitotriosidase-1 (hCHIT) catalytic domain in complex with compound 7g | | Descriptor: | 1-(5-azanyl-4~{H}-1,2,4-triazol-3-yl)-~{N}-[2-(4-bromophenyl)ethyl]-~{N}-(2-methylpropyl)piperidin-4-amine, Chitotriosidase-1, GLYCEROL | | Authors: | Mazur, M, Olczak, J, Olejniczak, S, Koralewski, R, Czestkowski, W, Jedrzejczak, A, Golab, J, Dzwonek, K, Dymek, B, Sklepkiewicz, P, Zagozdzon, A, Noonan, T, Mahboubi, K, Conway, B, Sheeler, R, Beckett, P, Hungerford, W.M, Podjarny, A, Mitschler, A, Cousido-Siah, A, Fadel, F, Golebiowski, A. | | Deposit date: | 2017-04-22 | | Release date: | 2018-03-28 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.267 Å) | | Cite: | Targeting Acidic Mammalian chitinase Is Effective in Animal Model of Asthma.
J. Med. Chem., 61, 2018
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5OOB
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5OO6
 | | Complex of human nuclear cap-binding complex with ARS2 C-terminal peptide | | Descriptor: | 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, Nuclear cap-binding protein subunit 1, Nuclear cap-binding protein subunit 2, ... | | Authors: | Cusack, S, Schulze, W.M. | | Deposit date: | 2017-08-06 | | Release date: | 2017-11-15 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structural basis for mutually exclusive co-transcriptional nuclear cap-binding complexes with either NELF-E or ARS2.
Nat Commun, 8, 2017
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1FJG
 | | STRUCTURE OF THE THERMUS THERMOPHILUS 30S RIBOSOMAL SUBUNIT IN COMPLEX WITH THE ANTIBIOTICS STREPTOMYCIN, SPECTINOMYCIN, AND PAROMOMYCIN | | Descriptor: | 16S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ... | | Authors: | Carter, A.P, Clemons Jr, W.M, Brodersen, D.E, Wimberly, B.T, Morgan-Warren, R.J, Ramakrishnan, V. | | Deposit date: | 2000-08-08 | | Release date: | 2000-09-25 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Functional insights from the structure of the 30S ribosomal subunit and its interactions with antibiotics
Nature, 407, 2000
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7UMB
 | | NanoBRET tracer Tram-bo bound to a KSR2-MEK1 complex | | Descriptor: | Dual specificity mitogen-activated protein kinase kinase 1, Kinase suppressor of Ras 2, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | | Authors: | Marsiglia, W.M, Khan, K.M, Dar, A.C. | | Deposit date: | 2022-04-06 | | Release date: | 2023-09-27 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (3.231 Å) | | Cite: | Live-cell target engagement of allosteric MEKi on MEK-RAF/KSR-14-3-3 complexes.
Nat.Chem.Biol., 20, 2024
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8HW5
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8IRK
 | | Carbon Sulfoxide lyase | | Descriptor: | PYRIDOXAL-5'-PHOSPHATE, PYRUVIC ACID, Probable hercynylcysteine sulfoxide lyase | | Authors: | Gong, W.M, Wei, L.L, Liu, L. | | Deposit date: | 2023-03-18 | | Release date: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Structure of Mycobacterial ergothioneine-biosynthesis C-S lyase EgtE
To Be Published
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8K00
 | | RPA70N-MRE11 fusion | | Descriptor: | Double-strand break repair protein MRE11, Replication protein A 70 kDa DNA-binding subunit | | Authors: | Fu, W.M, Wu, Y.Y, Zhou, C. | | Deposit date: | 2023-07-07 | | Release date: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Structural characterization of human RPA70N association with DNA damage response proteins.
Elife, 12, 2023
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8JZY
 | | RPA70N-RAD9 fusion | | Descriptor: | Cell cycle checkpoint control protein RAD9A, Replication protein A 70 kDa DNA-binding subunit | | Authors: | Fu, W.M, Wu, Y.Y, Zhou, C. | | Deposit date: | 2023-07-06 | | Release date: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Structural characterization of human RPA70N association with DNA damage response proteins.
Elife, 12, 2023
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8JZV
 | | RPA70N-ETAA1 fusion | | Descriptor: | Ewing's tumor-associated antigen 1, Replication protein A 70 kDa DNA-binding subunit | | Authors: | Fu, W.M, Wu, Y.Y, Zhou, C. | | Deposit date: | 2023-07-06 | | Release date: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Structural characterization of human RPA70N association with DNA damage response proteins.
Elife, 12, 2023
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3SZ7
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3UG7
 | | Crystal Structure of Get3 from Methanocaldococcus jannaschii | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ZINC ION, ... | | Authors: | Suloway, C.J.M, Rome, M.E, Clemons Jr, W.M. | | Deposit date: | 2011-11-02 | | Release date: | 2011-12-07 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.901 Å) | | Cite: | Tail-anchor targeting by a Get3 tetramer: the structure of an archaeal homologue.
Embo J., 31, 2012
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3UG6
 | | Crystal Structure of Get3 from Methanocaldococcus jannaschii | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ZINC ION, ... | | Authors: | Suloway, C.J.M, Rome, M.E, Clemons Jr, W.M. | | Deposit date: | 2011-11-02 | | Release date: | 2011-12-07 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Tail-anchor targeting by a Get3 tetramer: the structure of an archaeal homologue.
Embo J., 31, 2012
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3VEJ
 | | Crystal structure of the Get5 carboxyl domain from S. cerevisiae | | Descriptor: | PHOSPHATE ION, Ubiquitin-like protein MDY2 | | Authors: | Chartron, J.W, Vandervelde, D.G, Rao, M, Clemons Jr, W.M. | | Deposit date: | 2012-01-08 | | Release date: | 2012-01-25 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.23 Å) | | Cite: | Get5 Carboxyl-terminal Domain Is a Novel Dimerization Motif That Tethers an Extended Get4/Get5 Complex.
J.Biol.Chem., 287, 2012
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3LKU
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1DAV
 | | SOLUTION STRUCTURE OF THE TYPE I DOCKERIN DOMAIN FROM THE CLOSTRIDIUM THERMOCELLUM CELLULOSOME (20 STRUCTURES) | | Descriptor: | CALCIUM ION, ENDOGLUCANASE SS | | Authors: | Lytle, B.L, Volkman, B.F, Westler, W.M, Heckman, M.P, Wu, J.H.D. | | Deposit date: | 1999-10-31 | | Release date: | 2001-04-04 | | Last modified: | 2021-11-03 | | Method: | SOLUTION NMR | | Cite: | Solution structure of a type I dockerin domain, a novel prokaryotic, extracellular calcium-binding domain.
J.Mol.Biol., 307, 2001
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1DAQ
 | | SOLUTION STRUCTURE OF THE TYPE I DOCKERIN DOMAIN FROM THE CLOSTRIDIUM THERMOCELLUM CELLULOSOME (MINIMIZED AVERAGE STRUCTURE) | | Descriptor: | CALCIUM ION, ENDOGLUCANASE SS | | Authors: | Lytle, B.L, Volkman, B.F, Westler, W.M, Heckman, M.P, Wu, J.H.D. | | Deposit date: | 1999-10-31 | | Release date: | 2001-04-04 | | Last modified: | 2021-11-03 | | Method: | SOLUTION NMR | | Cite: | Solution structure of a type I dockerin domain, a novel prokaryotic, extracellular calcium-binding domain.
J.Mol.Biol., 307, 2001
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6XNT
 | | Crystal structure of I91A mutant of human CEACAM1 | | Descriptor: | Carcinoembryonic antigen-related cell adhesion molecule 1, octyl beta-D-glucopyranoside | | Authors: | Gandhi, A.K, Kim, W.M, Sun, Z.-Y, Huang, Y.H, Bonsor, D, Petsko, G.A, Kuchroo, V, Blumberg, R.S. | | Deposit date: | 2020-07-04 | | Release date: | 2021-03-24 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Structural basis of the dynamic human CEACAM1 monomer-dimer equilibrium.
Commun Biol, 4, 2021
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