Author results

6J0Z
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CRYSTAL STRUCTURE OF ALPK
分子名称:Putative angucycline-like polyketide oxygenase, FLAVIN-ADENINE DINUCLEOTIDE
著者Wang, W., Liu, Y., Liang, H.
登録日2018-12-27
公開日2019-03-06
実験手法X-RAY DIFFRACTION (2.889 Å)
主引用文献Crystal structure of AlpK: An essential monooxygenase involved in the biosynthesis of kinamycin
Biochem. Biophys. Res. Commun., 510, 2019
6MZC
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HUMAN TFIID BC CORE
分子名称:Transcription initiation factor TFIID subunit 2, Transcription initiation factor TFIID subunit 4, Transcription initiation factor TFIID subunit 5, ...
著者Patel, A.B., Louder, R.K., Greber, B.J., Grunberg, S., Luo, J., Fang, J., Liu, Y., Ranish, J., Hahn, S., Nogales, E.
登録日2018-11-05
公開日2018-11-28
最終更新日2019-11-20
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Structure of human TFIID and mechanism of TBP loading onto promoter DNA.
Science, 362, 2018
6MZD
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HUMAN TFIID LOBE A CANONICAL
分子名称:Transcription initiation factor TFIID subunit 1, Transcription initiation factor TFIID subunit 3, Transcription initiation factor TFIID subunit 4, ...
著者Patel, A.B., Louder, R.K., Greber, B.J., Grunberg, S., Luo, J., Fang, J., Liu, Y., Ranish, J., Hahn, S., Nogales, E.
登録日2018-11-05
公開日2018-11-28
最終更新日2019-11-20
実験手法ELECTRON MICROSCOPY (9.8 Å)
主引用文献Structure of human TFIID and mechanism of TBP loading onto promoter DNA.
Science, 362, 2018
6MZL
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HUMAN TFIID CANONICAL STATE
分子名称:Transcription initiation factor TFIID subunit 1, Transcription initiation factor TFIID subunit 2, Transcription initiation factor TFIID subunit 3, ...
著者Patel, A.B., Louder, R.K., Greber, B.J., Grunberg, S., Luo, J., Fang, J., Liu, Y., Ranish, J., Hahn, S., Nogales, E.
登録日2018-11-05
公開日2018-11-28
最終更新日2019-11-20
実験手法ELECTRON MICROSCOPY (23 Å)
主引用文献Structure of human TFIID and mechanism of TBP loading onto promoter DNA.
Science, 362, 2018
6MZM
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HUMAN TFIID BOUND TO PROMOTER DNA AND TFIIA
分子名称:Transcription initiation factor TFIID subunit 1, TAF1, Transcription initiation factor TFIID subunit 2, ...
著者Patel, A.B., Louder, R.K., Greber, B.J., Grunberg, S., Luo, J., Fang, J., Liu, Y., Ranish, J., Hahn, S., Nogales, E.
登録日2018-11-05
公開日2018-11-28
最終更新日2019-11-20
実験手法ELECTRON MICROSCOPY (7.5 Å)
主引用文献Structure of human TFIID and mechanism of TBP loading onto promoter DNA.
Science, 362, 2018
6OJ0
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CRYO-EM RECONSTRUCTION OF SULFOLOBUS POLYHEDRAL VIRUS 1 (SPV1)
分子名称:Structural protein VP4, Uncharacterized protein
著者Wang, F., Liu, Y., Conway, J.F., Krupovic, M., Prangishvili, D., Egelman, E.H.
登録日2019-04-10
公開日2019-10-02
最終更新日2019-11-20
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献A packing for A-form DNA in an icosahedral virus.
Proc.Natl.Acad.Sci.USA, 116, 2019
6R47
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THE STRUCTURE OF PISTOL RIBOZYME BOUND TO MAGNESIUM
分子名称:RNA (50-MER), RNA, MAGNESIUM ION
著者Lilley, D.M.J., Wilson, T.M., Liu, Y.
登録日2019-03-22
公開日2019-07-03
最終更新日2019-08-21
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Comparison of the Structures and Mechanisms of the Pistol and Hammerhead Ribozymes.
J.Am.Chem.Soc., 141, 2019
6FKQ
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THE CRYSTAL STRUCTURE OF A FRAGMENT OF NETRIN-1 IN COMPLEX WITH A FRAGMENT OF DRAXIN
分子名称:Netrin-1, Draxin, N-ACETYL-D-GLUCOSAMINE, ...
著者Bhowmick, T., Meijers, R.
登録日2018-01-24
公開日2018-03-21
最終更新日2018-04-04
実験手法X-RAY DIFFRACTION (3.07 Å)
主引用文献Structural Basis for Draxin-Modulated Axon Guidance and Fasciculation by Netrin-1 through DCC.
Neuron, 97, 2018
6AZR
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CRYSTAL STRUCTURE OF THE T264A HK853CP-BEF3-RR468 COMPLEX
分子名称:Sensor histidine kinase, Chemotaxis regulator-transmits chemoreceptor signals to flagelllar motor components CheY, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
著者Rose, J., Zhou, P.
登録日2017-09-11
公開日2017-12-27
実験手法X-RAY DIFFRACTION (3.628 Å)
主引用文献A pH-gated conformational switch regulates the phosphatase activity of bifunctional HisKA-family histidine kinases.
Nat Commun, 8, 2017
2OD1
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SOLUTION STRUCTURE OF THE MYND DOMAIN FROM HUMAN AML1-ETO
分子名称:Protein CBFA2T1, ZINC ION
著者Liu, Y.Z., Chen, W., Gaudet, J., Cheney, M.D., Roudaia, L., Cierpicki, T., Klet, R.C., Hartman, K., Laue, T.M., Speck, N.A., Bushweller, J.H.
登録日2006-12-21
公開日2007-06-19
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Structural basis for recognition of SMRT/N-CoR by the MYND domain and its contribution to AML1/ETO's activity.
Cancer Cell, 11, 2007
2ODD
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SOLUTION STRUCTURE OF THE MYND DOMAIN FROM AML1-ETO COMPLEXED WITH SMRT, A COREPRESSOR
分子名称:SMRT, Protein CBFA2T1, ZINC ION
著者Liu, Y.Z., Chen, W., Gaudet, J., Cheney, M.D., Roudaia, L., Cierpicki, T., Klet, R.C., Hartman, K., Laue, T.M., Speck, N.A., Bushweller, J.H.
登録日2006-12-22
公開日2007-06-19
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Structural basis for recognition of SMRT/N-CoR by the MYND domain and its contribution to AML1/ETO's activity.
Cancer Cell, 11, 2007
3VFN
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CRYSTAL STRUCTURE OF HLA B*3508LPEP151A, HLA MUTANT ALA151
分子名称:MHC class I antigen, Beta-2-microglobulin, LPEP peptide from EBV, ...
著者Liu, Y., Rossjohn, J., Gras, S.
登録日2012-01-10
公開日2012-03-07
最終更新日2012-04-25
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献The Energetic Basis Underpinning T-cell Receptor Recognition of a Super-bulged Peptide Bound to a Major Histocompatibility Complex Class I Molecule.
J.Biol.Chem., 287, 2012
5CNQ
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CRYSTAL STRUCTURE OF THE HOLLIDAY JUNCTION-RESOLVING ENZYME GEN1 (WT) IN COMPLEX WITH PRODUCT DNA, MG2+ AND MN2+ IONS
分子名称:Nuclease-like protein, R, DNA (5'-D(*TP*GP*AP*GP*CP*GP*GP*TP*GP*GP*TP*TP*GP*GP*T)-3'), ...
著者Liu, Y.J., Freeman, A.D.J., Declais, A.C., Wilson, T.J., Gartner, A., Lilley, D.M.J.
登録日2015-07-17
公開日2015-12-30
最終更新日2016-01-13
実験手法X-RAY DIFFRACTION (2.602 Å)
主引用文献Crystal Structure of a Eukaryotic GEN1 Resolving Enzyme Bound to DNA.
Cell Rep, 13, 2015
5CO8
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CRYSTAL STRUCTURE OF THE HOLLIDAY JUNCTION-RESOLVING ENZYME GEN1 (WT) IN COMPLEX WITH PRODUCT DNA AND MG2+ ION
分子名称:DNA (31-MER), Nuclease-like protein, DNA (5'-D(*AP*GP*AP*CP*TP*GP*CP*AP*GP*TP*TP*GP*AP*GP*TP*C)-3'), ...
著者Liu, Y.J., Freeman, A.D.J., Declais, A.C., Wilson, T.J., Gartner, A., Lilley, D.M.J.
登録日2015-07-20
公開日2016-01-13
最終更新日2018-11-21
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal Structure of a Eukaryotic GEN1 Resolving Enzyme Bound to DNA.
Cell Rep, 13, 2015
5EB9
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CRYSTAL STRUCTURE OF CHICKEN CD8AA HOMODIMER
分子名称:CD8 alpha chain
著者Liu, Y.J., Qi, J.X., Xia, C.
登録日2015-10-18
公開日2016-09-14
実験手法X-RAY DIFFRACTION (2.006 Å)
主引用文献The structural basis of chicken, swine and bovine CD8 alpha alpha dimers provides insight into the co-evolution with MHC I in endotherm species.
Sci Rep, 6, 2016
5EDX
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CRYSTAL STRUCTURE OF SWINE CD8AA HOMODIMER
分子名称:CD8 alpha antigen
著者Liu, Y.J., Qi, J.X., Zhang, N.Z., Xia, C.
登録日2015-10-22
公開日2016-09-14
実験手法X-RAY DIFFRACTION (1.801 Å)
主引用文献The structural basis of chicken, swine and bovine CD8 alpha alpha dimers provides insight into the co-evolution with MHC I in endotherm species.
Sci Rep, 6, 2016
5NS3
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CRYSTAL STRUCTURES OF CY5 CYANINE FLUOROPHORES STACKED ONTO THE END OF DOUBLE-STRANDED RNA
分子名称:50S ribosomal protein L5, double-stranded RNA
著者Liu, Y.J., Lilley, D.M.J.
登録日2017-04-25
公開日2017-12-20
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal Structures of Cyanine Fluorophores Stacked onto the End of Double-Stranded RNA.
Biophys. J., 113, 2017
5NS4
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CRYSTAL STRUCTURES OF CY3 CYANINE FLUOROPHORES STACKED ONTO THE END OF DOUBLE-STRANDED RNA
分子名称:50S ribosomal protein L5, RNA (34-MER), MAGNESIUM ION, ...
著者Liu, Y.J., Lilley, D.M.J.
登録日2017-04-25
公開日2017-12-20
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal Structures of Cyanine Fluorophores Stacked onto the End of Double-Stranded RNA.
Biophys. J., 113, 2017
5UXZ
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X-RAY CRYSTAL STRUCTURE OF HALOTAG BOUND TO THE P9 BENZOTHIADIAZOLE FLUOROGENIC LIGAND
分子名称:Haloalkane dehalogenase, N~2~-{[7-(dimethylamino)-2,1,3-benzothiadiazol-4-yl]sulfonyl}-N-hexyl-N~2~-methylglycinamide, CHLORIDE ION, ...
著者Dunham, N.P., Boal, A.K.
登録日2017-02-23
公開日2017-03-08
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献The Cation-pi Interaction Enables a Halo-Tag Fluorogenic Probe for Fast No-Wash Live Cell Imaging and Gel-Free Protein Quantification.
Biochemistry, 56, 2017
5UY1
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X-RAY CRYSTAL STRUCTURE OF APO HALOTAG
分子名称:Haloalkane dehalogenase, 1,2-ETHANEDIOL, CHLORIDE ION
著者Dunham, N.P., Boal, A.K.
登録日2017-02-23
公開日2017-03-08
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献The Cation-pi Interaction Enables a Halo-Tag Fluorogenic Probe for Fast No-Wash Live Cell Imaging and Gel-Free Protein Quantification.
Biochemistry, 56, 2017
5XZ3
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THE X-RAY STRUCTURE OF APIS MELLIFERA PGRP-SA
分子名称:Peptidoglycan-recognition protein, SULFATE ION
著者Liu, Y.J., Huang, J.X., Zhao, X.M., An, J.D.
登録日2017-07-11
公開日2018-07-18
最終更新日2019-01-30
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Crystal structure of peptidoglycan recognition protein SA in Apis mellifera (Hymenoptera: Apidae).
Protein Sci., 27, 2018
3WKR
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CRYSTAL STRUCTURE OF THE SEPCYSS-SEPCYSE COMPLEX FROM METHANOCALDOCOCCUS JANNASCHII
分子名称:O-phospho-L-seryl-tRNA:Cys-tRNA synthase, Uncharacterized protein MJ1481
著者Nakazawa, Y., Asano, N., Nakamura, A., Yao, M.
登録日2013-10-30
公開日2014-07-16
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (2.803 Å)
主引用文献Ancient translation factor is essential for tRNA-dependent cysteine biosynthesis in methanogenic archaea
Proc.Natl.Acad.Sci.USA, 2014
3WKS
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CRYSTAL STRUCTURE OF THE SEPCYSS-SEPCYSE N-TERMINAL DOMAIN COMPLEX FROM
分子名称:O-phospho-L-seryl-tRNA:Cys-tRNA synthase, Uncharacterized protein MJ1481
著者Nakazawa, Y., Asano, N., Nakamura, A., Yao, M.
登録日2013-10-30
公開日2014-07-30
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (3.029 Å)
主引用文献Ancient translation factor is essential for tRNA-dependent cysteine biosynthesis in methanogenic archaea
Proc.Natl.Acad.Sci.USA, 2014
4FGX
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CRYSTAL STRUCTURE OF BACE1 WITH NOVEL INHIBITOR
分子名称:Beta-secretase 1, Inhibitor (2R,5S,8S,12S,13S,16S,19S,22S)-16-(3-amino-3-oxopropyl)-2,13-dibenzyl-12,22-dihydroxy-8-isobutyl-19-isopropyl-3,5,17-trimethyl-4,7,10,15,18,21-hexaoxo-3,6,9,14,17,20-hexaazatricosan-1-oic acid, SULFATE ION, ...
著者Chen, T.T., Chen, W.Y., Li, L., Xu, Y.C.
登録日2012-06-05
公開日2013-01-16
実験手法X-RAY DIFFRACTION (1.59 Å)
主引用文献Cyanobacterial Peptides as a Prototype for the Design of Potent beta-Secretase Inhibitors and the Development of Selective Chemical Probes for Other Aspartic Proteases
J.Med.Chem., 55, 2012
4OU1
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CRYSTAL STRUCTURE OF A COMPUTATIONALLY DESIGNED RETRO-ALDOLASE COVALENTLY BOUND TO FOLDING PROBE 1 [(6-METHOXYNAPHTHALEN-2-YL)(OXIRAN-2-YL)METHANOL]
分子名称:Retro-aldolase, design RA114, (1S,2S)-1-(6-methoxynaphthalen-2-yl)propane-1,2-diol, ...
著者Bhabha, G., Zhang, X., Ekiert, D.C.
登録日2014-02-14
公開日2014-03-05
最終更新日2014-04-23
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Small molecule probes to quantify the functional fraction of a specific protein in a cell with minimal folding equilibrium shifts.
Proc.Natl.Acad.Sci.USA, 111, 2014