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4O7X
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CRYSTAL STRUCTURE OF HUMAN ALKBH5 IN COMPLEX WITH MN2+
分子名称:RNA demethylase ALKBH5, MANGANESE (II) ION
著者Feng, C., Chen, Z., Liu, Y.
登録日2013-12-26
公開日2014-03-19
最終更新日2015-10-21
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Crystal structures of the human RNA demethylase Alkbh5 reveal basis for substrate recognition
J.Biol.Chem., 289, 2014
4RZF
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CRYSTAL STRUCTURE ANALYSIS OF THE NUR77 LIGAND BINDING DOMAIN, S441W MUTANT
分子名称:Nuclear receptor subfamily 4 group A member 1, GLYCEROL
著者Li, F., Tian, X., Li, A., Li, L., Liu, Y., Chen, H., Wu, Q., Lin, T.
登録日2014-12-21
公開日2015-03-18
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Impeding the interaction between Nur77 and p38 reduces LPS-induced inflammation.
Nat.Chem.Biol., 11, 2015
4RZG
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CRYSTAL STRUCTURE ANALYSIS OF THE DNPA-BOUNDED NUR77 LIGAND BINDING DOMAIN
分子名称:Nuclear receptor subfamily 4 group A member 1, GLYCEROL, pentyl (3,5-dihydroxy-2-nonanoylphenyl)acetate
著者Li, F., Tian, X., Li, A., Li, L., Liu, Y., Chen, H., Wu, Q., Lin, T.
登録日2014-12-21
公開日2015-03-18
最終更新日2015-05-06
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Impeding the interaction between Nur77 and p38 reduces LPS-induced inflammation.
Nat.Chem.Biol., 11, 2015
5GT5
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STRUCTURAL BASIS OF THE SPECIFIC ACTIVITY AND THERMOSTABILITY OF PECTATE LYASE (PELN) FROM PAENIBACILLUS SP. 0602
分子名称:Pectate lyase
著者Zhou, Z.P., Liu, Y., Song, J.N.
登録日2016-08-18
公開日2017-10-25
実験手法X-RAY DIFFRACTION (1.449 Å)
主引用文献Structure-based engineering of a pectate lyase with improved specific activity for ramie degumming.
Appl. Microbiol. Biotechnol., 101, 2017
5YLC
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CRYSTAL STRUCTURE OF MCR-1 CATALYTIC DOMAIN
分子名称:Probable phosphatidylethanolamine transferase Mcr-1, ZINC ION
著者Wei, P.C., Song, G.J., Shi, M.Y., Zhou, Y.F., Liu, Y., Lei, J., Chen, P., Yin, L.
登録日2017-10-17
公開日2017-11-08
最終更新日2018-03-07
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Substrate analog interaction with MCR-1 offers insight into the rising threat of the plasmid-mediated transferable colistin resistance.
FASEB J., 32, 2018
5YLE
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MCR-1 COMPLEX WITH ETHANOLAMINE (ETA)
分子名称:Probable phosphatidylethanolamine transferase Mcr-1, ETHANOLAMINE, ZINC ION
著者Wei, P.C., Song, G.J., Shi, M.Y., Zhou, Y.F., Liu, Y., Lei, J., Chen, P., Yin, L.
登録日2017-10-17
公開日2017-11-08
最終更新日2018-03-07
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Substrate analog interaction with MCR-1 offers insight into the rising threat of the plasmid-mediated transferable colistin resistance.
FASEB J., 32, 2018
5YLF
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MCR-1 COMPLEX WITH D-GLUCOSE
分子名称:Probable phosphatidylethanolamine transferase Mcr-1, BETA-D-GLUCOSE, ZINC ION
著者Wei, P.C., Song, G.J., Shi, M.Y., Zhou, Y.F., Liu, Y., Lei, J., Chen, P., Yin, L.
登録日2017-10-17
公開日2017-11-08
最終更新日2018-03-07
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Substrate analog interaction with MCR-1 offers insight into the rising threat of the plasmid-mediated transferable colistin resistance.
FASEB J., 32, 2018
1BM8
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DNA-BINDING DOMAIN OF MBP1
分子名称:TRANSCRIPTION FACTOR MBP1
著者Xu, R.-M., Koch, C., Liu, Y., Horton, J.R., Knapp, D., Nasmyth, K., Cheng, X.
登録日1998-07-29
公開日1999-03-02
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.71 Å)
主引用文献Crystal structure of the DNA-binding domain of Mbp1, a transcription factor important in cell-cycle control of DNA synthesis.
Structure, 5, 1997
1FU5
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NMR STRUCTURE OF THE N-SH2 DOMAIN OF THE P85 SUBUNIT OF PI3-KINASE COMPLEXED TO A DOUBLY PHOSPHORYLATED PEPTIDE DERIVED FROM POLYOMAVIRUS MIDDLE T ANTIGEN
分子名称:PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY ALPHA SUBUNIT, DOUBLY PHOSPHORYLATED MIDDLE T ANTIGEN
著者Weber, T., Schaffhausen, B., Liu, Y., Guenther, U.L.
登録日2000-09-14
公開日2001-02-21
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献NMR structure of the N-SH2 of the p85 subunit of phosphoinositide 3-kinase complexed to a doubly phosphorylated peptide reveals a second phosphotyrosine binding site.
Biochemistry, 39, 2000
1FU6
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NMR STRUCTURE OF THE N-SH2 DOMAIN OF THE P85 SUBUNIT OF PI3-KINASE
分子名称:PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY ALPHA SUBUNIT
著者Weber, T., Schaffhausen, B., Liu, Y., Guenther, U.L.
登録日2000-09-14
公開日2001-02-21
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献NMR structure of the N-SH2 of the p85 subunit of phosphoinositide 3-kinase complexed to a doubly phosphorylated peptide reveals a second phosphotyrosine binding site.
Biochemistry, 39, 2000
1H2I
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HUMAN RAD52 PROTEIN, N-TERMINAL DOMAIN
分子名称:DNA REPAIR PROTEIN RAD52 HOMOLOG
著者Singleton, M.R., Wentzell, L.M., Liu, Y., West, S.C., Wigley, D.B.
登録日2002-08-09
公開日2002-10-10
最終更新日2017-07-05
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure of the Single-Strand Annealing Domain of Human Rad52 Protein
Proc.Natl.Acad.Sci.USA, 99, 2002
1HCN
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STRUCTURE OF HUMAN CHORIONIC GONADOTROPIN AT 2.6 ANGSTROMS RESOLUTION FROM MAD ANALYSIS OF THE SELENOMETHIONYL PROTEIN
分子名称:HUMAN CHORIONIC GONADOTROPIN, N-ACETYL-D-GLUCOSAMINE
著者Wu, H., Lustbader, J.W., Liu, Y., Canfield, R.E., Hendrickson, W.A.
登録日1994-07-01
公開日1994-09-30
最終更新日2019-08-14
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure of human chorionic gonadotropin at 2.6 A resolution from MAD analysis of the selenomethionyl protein.
Structure, 2, 1994
1KSW
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STRUCTURE OF HUMAN C-SRC TYROSINE KINASE (THR338GLY MUTANT) IN COMPLEX WITH N6-BENZYL ADP
分子名称:PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC, N6-BENZYL ADENOSINE-5'-DIPHOSPHATE
著者Witucki, L.A., Huang, X., Shah, K., Liu, Y., Kyin, S., Eck, M.J., Shokat, K.M.
登録日2002-01-14
公開日2002-02-27
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Mutant tyrosine kinases with unnatural nucleotide specificity retain the structure and phospho-acceptor specificity of the wild-type enzyme.
Chem.Biol., 9, 2002
1NH9
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CRYSTAL STRUCTURE OF A DNA BINDING PROTEIN MJA10B FROM THE HYPERTHERMOPHILE METHANOCOCCUS JANNASCHII
分子名称:DNA-binding protein Alba
著者Wang, G., Bartlam, M., Guo, R., Yang, H., Xue, H., Liu, Y., Huang, L., Rao, Z.
登録日2002-12-19
公開日2003-12-23
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of a DNA binding protein from the hyperthermophilic euryarchaeon Methanococcus jannaschii
Protein Sci., 12, 2003
1NXK
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CRYSTAL STRUCTURE OF STAUROSPORINE BOUND TO MAP KAP KINASE 2
分子名称:MAP kinase-activated protein kinase 2, STAUROSPORINE, SULFATE ION
著者Underwood, K.W., Parris, K.D., Federico, E., Mosyak, L., Czerwinski, R.M., Shane, T., Taylor, M., Svenson, K., Liu, Y., Hsiao, C.L., Wolfrom, S., Malakian, K., Telliez, J.B., Lin, L.L., Kriz, R.W., Seehra, J., Somers, W.S., Stahl, M.L.
登録日2003-02-10
公開日2003-10-14
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Catalytically active MAP KAP kinase 2 structures in complex with staurosporine and ADP reveal differences with the autoinhibited enzyme
Structure, 11, 2003
1NY3
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CRYSTAL STRUCTURE OF ADP BOUND TO MAP KAP KINASE 2
分子名称:MAP kinase-activated protein kinase 2, ADENOSINE-5'-DIPHOSPHATE
著者Underwood, K.W., Parris, K.D., Federico, E., Mosyak, L., Shane, T., Taylor, M., Svenson, K., Liu, Y., Hsiao, C.L., Wolfrom, S., Maguire, M., Malakian, K., Telliez, J.B., Lin, L.L., Kriz, R.W., Seehra, J., Somers, W.S., Stahl, M.L.
登録日2003-02-11
公開日2003-10-14
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Catalytically active MAP KAP kinase 2 structures in complex with staurosporine and ADP reveal differences with the autoinhibited enzyme
Structure, 11, 2003
1Q67
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CRYSTAL STRUCTURE OF DCP1P
分子名称:Decapping protein involved in mRNA degradation-Dcp1p
著者She, M., Decker, C.J., Liu, Y., Chen, N., Parker, R., Song, H.
登録日2003-08-12
公開日2004-03-02
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of Dcp1p and its functional implications in mRNA decapping
Nat.Struct.Mol.Biol., 11, 2004
1RKP
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CRYSTAL STRUCTURE OF PDE5A1-IBMX
分子名称:cGMP-specific 3',5'-cyclic phosphodiesterase, ZINC ION, MAGNESIUM ION, ...
著者Huai, Q., Liu, Y., Francis, S.H., Corbin, J.D., Ke, H.
登録日2003-11-22
公開日2004-03-30
最終更新日2018-01-31
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Crystal structures of phosphodiesterases 4 and 5 in complex with inhibitor IBMX suggest a conformation determinant of inhibitor selectivity
J.Biol.Chem., 279, 2004
1T1J
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CRYSTAL STRUCTURE OF GENOMICS APC5043
分子名称:hypothetical protein
著者Dong, A., Xu, X., Liu, Y., Zhang, R., Savchenko, A., Edwards, A., Midwest Center for Structural Genomics (MCSG)
登録日2004-04-16
公開日2004-08-03
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal Structure of Conserved Hypothetical Protein PA1492 from Pseudomonas aeruginosa
TO BE PUBLISHED
1Y4E
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NMR STRUCTURE OF TRANSMEMBRANE SEGMENT IV OF THE NHE1 ISOFORM OF THE NA+/H+ EXCHANGER
分子名称:Sodium/hydrogen exchanger 1
著者Slepkov, E.R., Rainey, J.K., Li, X., Liu, Y., Lindhout, D.A., Sykes, B.D., Fliegel, L.
登録日2004-11-30
公開日2005-02-01
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Structural and functional characterization of transmembrane segment IV of the NHE1 isoform of the Na+/H+ exchanger.
J.Biol.Chem., 280, 2005
1Y4S
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CONFORMATION REARRANGEMENT OF HEAT SHOCK PROTEIN 90 UPON ADP BINDING
分子名称:Chaperone protein htpG, MAGNESIUM ION, ADENOSINE-5'-DIPHOSPHATE
著者Huai, Q., Wang, H., Liu, Y., Kim, H., Toft, D., Ke, H.
登録日2004-12-01
公開日2005-04-19
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structures of the N-terminal and middle domains of E. coli Hsp90 and conformation changes upon ADP binding.
Structure, 13, 2005
1Y4U
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CONFORMATION REARRANGEMENT OF HEAT SHOCK PROTEIN 90 UPON ADP BINDING
分子名称:Chaperone protein htpG
著者Huai, Q., Wang, H., Liu, Y., Kim, H., Toft, D., Ke, H.
登録日2004-12-01
公開日2005-04-19
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structures of the N-terminal and middle domains of E. coli Hsp90 and conformation changes upon ADP binding.
Structure, 13, 2005
1YP1
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CRYSTAL STRUCTURE OF A NON-HEMORRHAGIC FIBRIN(OGEN)OLYTIC METALLOPROTEINASE FROM VENOM OF AGKISTRODON ACUTUS
分子名称:FII, KNL, ZINC ION
著者Lou, Z., Hou, J., Chen, J., Liang, X., Qiu, P., Liu, Y., Li, M., Rao, Z.
登録日2005-01-28
公開日2006-01-17
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of a non-hemorrhagic fibrin(ogen)olytic metalloproteinase complexed with a novel natural tri-peptide inhibitor from venom of Agkistrodon acutus
J.Struct.Biol., 152, 2005
1ZKN
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STRUCTURE OF PDE4D2-IBMX
分子名称:cAMP-specific 3',5'-cyclic phosphodiesterase 4D, ZINC ION, MAGNESIUM ION, ...
著者Huai, Q., Liu, Y., Francis, S.H., Corbin, J.D., Ke, H.
登録日2005-05-03
公開日2005-05-17
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal Structures of Phosphodiesterases 4 and 5 in Complex with Inhibitor 3-Isobutyl-1-Methylxanthine Suggest a Conformation Determinant of Inhibitor Selectivity
J.Biol.Chem., 279, 2004
2APQ
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CRYSTAL STRUCTURE OF AN ACTIVE SITE MUTANT OF BOVINE PANCREATIC RIBONUCLEASE A (H119A-RNASE A) WITH A 10-GLUTAMINE EXPANSION IN THE C-TERMINAL HINGE-LOOP.
分子名称:Ribonuclease, PHOSPHATE ION
著者Sambashivan, S., Liu, Y., Sawaya, M.R., Gingery, M., Eisenberg, D.
登録日2005-08-16
公開日2005-09-13
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Amyloid-like fibrils of ribonuclease A with three-dimensional domain-swapped and native-like structure.
Nature, 437, 2005