Author results

1FWL
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CRYSTAL STRUCTURE OF HOMOSERINE KINASE
Descriptor:HOMOSERINE KINASE
Authors:Zhou, T., Daugherty, M., Grishin, N.V., Osterman, A.L., Zhang, H.
Deposit date:2000-09-22
Release date:2000-12-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structure and mechanism of homoserine kinase: prototype for the GHMP kinase superfamily.
Structure Fold.Des., 8, 2000
1G5J
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COMPLEX OF BCL-XL WITH PEPTIDE FROM BAD
Descriptor:APOPTOSIS REGULATOR BCL-X, BAD PROTEIN
Authors:Petros, A.M., Nettesheim, D.G., Wang, Y., Olejniczak, E.T., Meadows, R.P., Mack, J., Swift, K., Matayoshi, E.D., Zhang, H., Thompson, C.B., Fesik, S.W.
Deposit date:2000-11-01
Release date:2001-02-07
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Rationale for Bcl-xL/Bad peptide complex formation from structure, mutagenesis, and biophysical studies.
Protein Sci., 9, 2000
1GKH
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MUTANT K69H OF GENE V PROTEIN (SINGLE-STRANDED DNA BINDING PROTEIN)
Descriptor:GENE V PROTEIN
Authors:Su, S., Gao, Y.-G., Zhang, H., Terwilliger, T.C., Wang, A.H.-J.
Deposit date:1997-03-04
Release date:1997-09-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Analyses of the stability and function of three surface mutants (R82C, K69H, and L32R) of the gene V protein from Ff phage by X-ray crystallography.
Protein Sci., 6, 1997
1GQ2
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MALIC ENZYME FROM PIGEON LIVER
Descriptor:MALIC ENZYME, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, OXALATE ION, ...
Authors:Yang, Z., Zhang, H., Liang, T.
Deposit date:2001-11-19
Release date:2002-05-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Studies of the Pigeon Cytosolic Nadp+ -Dependent Malic Enzyme
Protein Sci., 11, 2002
1GVP
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GENE V PROTEIN (SINGLE-STRANDED DNA BINDING PROTEIN)
Descriptor:GENE V PROTEIN
Authors:Su, S., Gao, Y.-G., Zhang, H., Terwilliger, T.C., Wang, A.H.-J.
Deposit date:1997-02-26
Release date:1997-09-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Analyses of the stability and function of three surface mutants (R82C, K69H, and L32R) of the gene V protein from Ff phage by X-ray crystallography.
Protein Sci., 6, 1997
1IM8
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CRYSTAL STRUCTURE OF YECO FROM HAEMOPHILUS INFLUENZAE (HI0319), A METHYLTRANSFERASE WITH A BOUND S-ADENOSYLHOMOCYSTEINE
Descriptor:YecO, CHLORIDE ION, S-ADENOSYL-L-HOMOSELENOCYSTEINE
Authors:Lim, K., Zhang, H., Tempczyk, A., Bonander, N., Toedt, J., Howard, A., Eisenstein, E., Herzberg, O., Structure 2 Function Project (S2F)
Deposit date:2001-05-10
Release date:2001-11-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of YecO from Haemophilus influenzae (HI0319) reveals a methyltransferase fold and a bound S-adenosylhomocysteine.
Proteins, 45, 2001
1J85
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STRUCTURE OF YIBK FROM HAEMOPHILUS INFLUENZAE (HI0766), A TRUNCATED SEQUENCE HOMOLOG OF TRNA (GUANOSINE-2'-O-) METHYLTRANSFERASE (SPOU)
Descriptor:YibK
Authors:Lim, K., Zhang, H., Toedt, J., Tempcyzk, A., Krajewski, W., Howard, A., Eisenstein, E., Herzberg, O., Structure 2 Function Project (S2F)
Deposit date:2001-05-20
Release date:2003-02-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of the YibK methyltransferase from Haemophilus influenzae (HI0766): A cofactor bound at a site formed by a knot
Proteins, 51, 2003
1KQN
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CRYSTAL STRUCTURE OF NMN/NAMN ADENYLYLTRANSFERASE COMPLEXED WITH NAD
Descriptor:NICOTINAMIDE MONONUCLEOTIDE ADENYLYL TRANSFERASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, XENON
Authors:Zhou, T., Kurnasov, O., Tomchick, D.R., Binns, D.D., Grishin, N.V., Marquez, V.E., Osterman, A.L., Zhang, H.
Deposit date:2002-01-07
Release date:2003-01-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of Human Nicotinamide/Nicotonic Acid Mononucleotide Adenylyltransferase. Basis for the dual substrate specificity and activation of the oncolytic agent tiazofurin.
J.Biol.Chem., 277, 2003
1KQO
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CRYSTAL STRUCTURE OF NMN/NAMN ADENYLYLTRANSFERASE COMPLEXED WITH DEAMIDO-NAD
Descriptor:NICOTINAMIDE MONONUCLEOTIDE ADENYLYL TRANSFERASE, NICOTINIC ACID ADENINE DINUCLEOTIDE
Authors:Zhou, T., Kurnasov, O., Tomchick, D.R., Binns, D.D., Grishin, N.V., Marquez, V.E., Osterman, A.L., Zhang, H.
Deposit date:2002-01-07
Release date:2003-01-07
Last modified:2014-10-22
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of Hhuman of Nicotinamide/Nicotinic Acid Mononucleotide Adenylyltransferase. Basis for the dual substrate specificity and activation of the oncolytic agent tiazofurin.
J.Biol.Chem., 277, 2002
1KR2
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CRYSTAL STRUCTURE OF HUMAN NMN/NAMN ADENYLYL TRANSFERASE COMPLEXED WITH TIAZOFURIN ADENINE DINUCLEOTIDE (TAD)
Descriptor:NICOTINAMIDE MONONUCLEOTIDE ADENYLYL TRANSFERASE, BETA-METHYLENE-THIAZOLE-4-CARBOXYAMIDE-ADENINE DINUCLEOTIDE
Authors:Zhou, T., Kurnasov, O., Tomchick, D.R., Binns, D.D., Grishin, N.V., Marquez, V.E., Osterman, A.L., Zhang, H.
Deposit date:2002-01-08
Release date:2003-01-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of Hhuman of Nicotinamide/Nicotinic Acid Mononucleotide Adenylyltransferase. Basis for the dual substrate specificity and activation of the oncolytic agent tiazofurin.
J.Biol.Chem., 277, 2002
1M32
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CRYSTAL STRUCTURE OF 2-AMINOETHYLPHOSPHONATE TRANSAMINASE
Descriptor:2-aminoethylphosphonate-pyruvate aminotransferase, PYRIDOXAL-5'-PHOSPHATE, PHOSPHONOACETALDEHYDE, ...
Authors:Chen, C.C.H., Zhang, H., Kim, A.D., Howard, A., Sheldrick, G.M., Mariano-Dunnaway, D., Herzberg, O.
Deposit date:2002-06-26
Release date:2002-11-20
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Degradation Pathway of the Phosphonate Ciliatine: Crystal Structure of 2-Aminoethylphosphonate Transaminase
Biochemistry, 41, 2002
1M4M
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MOUSE SURVIVIN
Descriptor:BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 5, ZINC ION
Authors:Muchmore, S.W., Chen, J., Jakob, C., Zakula, D., Matayoshi, E.D., Wu, W., Zhang, H., Li, F., Ng, S.C., Altieri, D.C.
Deposit date:2002-07-03
Release date:2002-09-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:CRYSTAL STRUCTURE AND MUTAGENIC ANALYSIS OF THE INHIBITOR-OF-APOPTOSIS PROTEIN SURVIVIN
MOL.CELL, 6, 2000
1MXI
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STRUCTURE OF YIBK FROM HAEMOPHILUS INFLUENZAE (HI0766): A METHYLTRANSFERASE WITH A COFACTOR BOUND AT A SITE FORMED BY A KNOT
Descriptor:Hypothetical tRNA/rRNA methyltransferase HI0766, IODIDE ION, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Lim, K., Zhang, H., Tempczyk, A., Bonander, N., Toedt, J., Howard, A., Eisenstein, E., Herzberg, O., Structure 2 Function Project (S2F)
Deposit date:2002-10-02
Release date:2003-02-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure of the YibK methyltransferase from Haemophilus influenzae (HI0766): a Cofactor Bound at a Site Formed by a Knot
Proteins, 51, 2003
1NB0
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CRYSTAL STRUCTURE OF HUMAN RIBOFLAVIN KINASE
Descriptor:hypothetical protein FLJ11149, MAGNESIUM ION, ADENOSINE-5'-DIPHOSPHATE
Authors:Karthikeyan, S., Zhou, Q., Mseeh, F., Grishin, N.V., Osterman, A.L., Zhang, H.
Deposit date:2002-12-01
Release date:2003-03-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal Structure of Human Riboflavin Kinase Reveals a Beta Barrel Fold and a Novel Active Site Arch
Structure, 11, 2003
1NB9
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CRYSTAL STRUCTURE OF RIBOFLAVIN KINASE
Descriptor:hypothetical protein FLJ11149, MAGNESIUM ION, ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Karthikeyan, S., Zhou, Q., Mseeh, F., Grishin, N.V., Osterman, A.L., Zhang, H.
Deposit date:2002-12-02
Release date:2003-03-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal Structure of Human Riboflavin Kinase Reveals a Beta Barrel Fold and a Novel Active Site Arch
Structure, 11, 2003
1NI1
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IMIDAZOLE AND CYANOPHENYL FARNESYL TRANSFERASE INHIBITORS
Descriptor:Protein farnesyltransferase alpha subunit, Protein farnesyltransferase beta subunit, ZINC ION, ...
Authors:Tong, Y., Lin, N.H., Wang, L., Hasvold, L., Wang, W., Leonard, N., Li, T., Li, Q., Cohen, J., Gu, W.Z., Zhang, H., Stoll, V., Bauch, J., Marsh, K., Rosenberg, S.H., Sham, H.L.
Deposit date:2002-12-20
Release date:2004-04-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Discovery of potent imidazole and cyanophenyl containing farnesyltransferase inhibitors with improved oral bioavailability.
Bioorg.Med.Chem.Lett., 13, 2003
1P4M
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CRYSTAL STRUCTURE OF RIBOFLAVIN KINASE
Descriptor:RIBOFLAVIN KINASE, MAGNESIUM ION, ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Karthikeyan, S., Zhou, Q., Mseeh, F., Grishin, N.V., Osterman, A.L., Zhang, H.
Deposit date:2003-04-23
Release date:2003-05-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structure of Human Riboflavin Kinase Reveals a Beta Barrel Fold and a Novel Active Site Arch
Structure, 11, 2003
1Q9S
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CRYSTAL STRUCTURE OF RIBOFLAVIN KINASE WITH TERNARY PRODUCT COMPLEX
Descriptor:hypothetical protein FLJ11149, MAGNESIUM ION, ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Karthikeyan, S., Zhou, Q., Osterman, A.L., Zhang, H.
Deposit date:2003-08-25
Release date:2003-12-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.42 Å)
Cite:Ligand binding-induced conformational changes in riboflavin kinase: structural basis for the ordered mechanism.
Biochemistry, 42, 2003
1QKK
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CRYSTAL STRUCTURE OF THE RECEIVER DOMAIN AND LINKER REGION OF DCTD FROM SINORHIZOBIUM MELILOTI
Descriptor:C4-DICARBOXYLATE TRANSPORT TRANSCRIPTIONAL REGULATORY PROTEIN
Authors:Meyer, M.G., Park, S., Zeringue, L., Staley, M., Mckinstry, M., Kaufman, R.I., Zhang, H., Yan, D., Yennawar, N., Farber, G.K., Nixon, B.T.
Deposit date:1999-07-23
Release date:2000-07-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:A Dimeric Two-Component Receiver Domain Inhibits the Sigma54-Dependent ATPase in Dctd
Faseb J., 15, 2001
1RQX
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CRYSTAL STRUCTURE OF ACC DEAMINASE COMPLEXED WITH INHIBITOR
Descriptor:1-aminocyclopropane-1-carboxylate deaminase, PYRIDOXAL-5'-PHOSPHATE, 1-AMINOCYCLOPROPYLPHOSPHONATE
Authors:Karthikeyan, S., Zhao, Z., Kao, C.L., Zhou, Q., Tao, Z., Zhang, H., Liu, H.W.
Deposit date:2003-12-07
Release date:2004-08-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural analysis of 1-aminocyclopropane-1-carboxylate deaminase: observation of an aminyl intermediate and identification of Tyr 294 as the active-site nucleophile.
Angew.Chem.Int.Ed.Engl., 43, 2004
1W5V
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HIV-1 PROTEASE IN COMPLEX WITH FLUORO SUBSTITUTED DIOL-BASED C2- SYMMETRIC INHIBITOR
Descriptor:HIV-1 PROTEASE, N,N-[2,5-O-DI-3-FLUORO-BENZYL-GLUCARYL]-DI-[1-AMINO-INDAN-2-OL]
Authors:Lindberg, J., Pyring, D., Loewgren, S., Rosenquist, A., Zuccarello, G., Kvarnstroem, I., Zhang, H., Vrang, L., Claesson, B., Hallberg, A., Samuelsson, B., Unge, T.
Deposit date:2004-08-10
Release date:2004-12-01
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Symmetric Fluoro-Substituted Diol-Based HIV Protease Inhibitors. Ortho-Fluorinated and Meta-Fluorinated P1/P1'-Benzyloxy Side Groups Significantly Improve the Antiviral Activity and Preserve Binding Efficacy
Eur.J.Biochem., 271, 2004
1W5W
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HIV-1 PROTEASE IN COMPLEX WITH FLUORO SUBSTITUTED DIOL-BASED C2- SYMMETRIC INHIBITOR
Descriptor:POL POLYPROTEIN, (2R,3R,4R,5R)-2,5-BIS[(2,4-DIFLUOROBENZYL)OXY]-3,4-DIHYDROXY-N,N'-BIS[(1R,2S)-2-HYDROXY-2,3-DIHYDRO-1H-INDEN-1-YL]HEXANEDIAMIDE
Authors:Lindberg, J., Pyring, D., Loewgren, S., Rosenquist, A., Zuccarello, G., Kvarnstroem, I., Zhang, H., Vrang, L., Claesson, B., Hallberg, A., Samuelsson, B., Unge, T.
Deposit date:2004-08-10
Release date:2004-12-22
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Symmetric Fluoro-Substituted Diol-Based HIV Protease Inhibitors. Ortho-Fluorinated and Meta-Fluorinated P1/P1'-Benzyloxy Side Groups Significantly Improve the Antiviral Activity and Preserve Binding Efficacy
Eur.J.Biochem., 271, 2004
1W5X
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HIV-1 PROTEASE IN COMPLEX WITH FLUORO SUBSTITUTED DIOL-BASED C2- SYMMETRIC INHIBITOR
Descriptor:POL POLYPROTEIN, (2R,3R,4R,5R)-2,5-BIS[(2,3-DIFLUOROBENZYL)OXY]-3,4-DIHYDROXY-N,N'-BIS[(1S,2R)-2-HYDROXY-2,3-DIHYDRO-1H-INDEN-1-YL]HEXANEDIAMIDE
Authors:Lindberg, J., Pyring, D., Loewgren, S., Rosenquist, A., Zuccarello, G., Kvarnstroem, I., Zhang, H., Vrang, L., Claesson, B., Hallberg, A., Samuelsson, B., Unge, T.
Deposit date:2004-08-10
Release date:2004-12-22
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Symmetric Fluoro-Substituted Diol-Based HIV Protease Inhibitors. Ortho-Fluorinated and Meta-Fluorinated P1/P1'-Benzyloxy Side Groups Significantly Improve the Antiviral Activity and Preserve Binding Efficacy
Eur.J.Biochem., 271, 2004
1W5Y
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HIV-1 PROTEASE IN COMPLEX WITH FLUORO SUBSTITUTED DIOL-BASED C2- SYMMETRIC INHIBITOR
Descriptor:POL POLYPROTEIN, (2R,3R,4R,5R)-2,5-BIS[(2,5-DIFLUOROBENZYL)OXY]-3,4-DIHYDROXY-N,N'-BIS[(1S,2R)-2-HYDROXY-2,3-DIHYDRO-1H-INDEN-1-YL]HEXANEDIAMIDE
Authors:Lindberg, J., Pyring, D., Loewgren, S., Rosenquist, A., Zuccarello, G., Kvarnstroem, I., Zhang, H., Vrang, L., Claesson, B., Hallberg, A., Samuelsson, B., Unge, T.
Deposit date:2004-08-10
Release date:2004-10-07
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Symmetric Fluoro-Substituted Diol-Based HIV Protease Inhibitors. Ortho-Fluorinated and Meta-Fluorinated P1/P1'-Benzyloxy Side Groups Significantly Improve the Antiviral Activity and Preserve Binding Efficacy
Eur.J.Biochem., 271, 2004
1Y82
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CONSERVED HYPOTHETICAL PROTEIN PFU-367848-001 FROM PYROCOCCUS FURIOSUS
Descriptor:hypothetical protein, UNKNOWN ATOM OR ION
Authors:Horanyi, P., Tempel, W., Habel, J., Chen, L., Lee, D., Nguyen, D., Chang, S.-H., Florence, Q., Zhou, W., Lin, D., Zhang, H., Praissman, J., Jenney Jr., F.E., Adams, M.W.W., Liu, Z.-J., Rose, J.P., Wang, B.C., Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2004-12-10
Release date:2005-01-25
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Conserved hypothetical protein Pfu-367848-001 from Pyrococcus furiosus
To be published