Author results

3U9G
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CRYSTAL STRUCTURE OF THE ZINC FINGER ANTIVIRAL PROTEIN
分子名称:Zinc finger CCCH-type antiviral protein 1, ZINC ION
著者Chen, S., Xu, Y., Zhang, K., Wang, X., Sun, J., Gao, G., Liu, Y.
登録日2011-10-18
公開日2012-03-14
最終更新日2013-07-17
実験手法X-RAY DIFFRACTION (1.801 Å)
主引用文献Structure of N-terminal domain of ZAP indicates how a zinc-finger protein recognizes complex RNA.
Nat.Struct.Mol.Biol., 19, 2012
4G1T
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CRYSTAL STRUCTURE OF INTERFERON-STIMULATED GENE 54
分子名称:Interferon-induced protein with tetratricopeptide repeats 2
著者Yang, Z., Liang, H., Zhou, Q., Li, Y., Chen, H., Ye, W., Chen, D., Fleming, J., Shu, H., Liu, Y.
登録日2012-07-11
公開日2012-08-15
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of ISG54 reveals a novel RNA binding structure and potential functional mechanisms.
Cell Res., 2012
4GJH
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CRYSTAL STRUCTURE OF THE TRAF DOMAIN OF TRAF5
分子名称:TNF receptor-associated factor 5
著者Zhang, P., Reichardt, A., Liang, H., Wang, Y., Cheng, D., Aliyari, R., Cheng, G., Liu, Y.
登録日2012-08-09
公開日2012-11-28
実験手法X-RAY DIFFRACTION (2.805 Å)
主引用文献Single Amino Acid Substitutions Confer the Antiviral Activity of the TRAF3 Adaptor Protein onto TRAF5
Sci.Signal., 5, 2012
4ITH
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CRYSTAL STRUCTURE OF RIP1 KINASE IN COMPLEX WITH NECROSTATIN-1 ANALOG
分子名称:Receptor-interacting serine/threonine-protein kinase 1, IODIDE ION, SODIUM ION, ...
著者Xie, T., Peng, W., Liu, Y., Yan, C., Shi, Y.
登録日2013-01-18
公開日2013-03-13
最終更新日2013-03-27
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structural Basis of RIP1 Inhibition by Necrostatins.
Structure, 21, 2013
4ITI
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CRYSTAL STRUCTURE OF RIP1 KINASE IN COMPLEX WITH NECROSTATIN-3 ANALOG
分子名称:Receptor-interacting serine/threonine-protein kinase 1, 1-{(3S,3aS)-3-[3-fluoro-4-(trifluoromethoxy)phenyl]-8-methoxy-3,3a,4,5-tetrahydro-2H-benzo[g]indazol-2-yl}-2-hydroxyethanone
著者Xie, T., Peng, W., Liu, Y., Yan, C., Shi, Y.
登録日2013-01-18
公開日2013-03-13
最終更新日2013-03-27
実験手法X-RAY DIFFRACTION (2.86 Å)
主引用文献Structural Basis of RIP1 Inhibition by Necrostatins.
Structure, 21, 2013
4ITJ
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CRYSTAL STRUCTURE OF RIP1 KINASE IN COMPLEX WITH NECROSTATIN-4
分子名称:Receptor-interacting serine/threonine-protein kinase 1, N-[(1S)-1-(2-chloro-6-fluorophenyl)ethyl]-5-cyano-1-methyl-1H-pyrrole-2-carboxamide, IODIDE ION
著者Xie, T., Peng, W., Liu, Y., Yan, C., Shi, Y.
登録日2013-01-18
公開日2013-03-13
最終更新日2013-03-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural Basis of RIP1 Inhibition by Necrostatins.
Structure, 21, 2013
4M7C
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CRYSTAL STRUCTURE OF THE TRF2-BINDING MOTIF OF SLX4 IN COMPLEX WITH THE TRFH DOMAIN OF TRF2
分子名称:Telomeric repeat-binding factor 2, Peptide from Structure-specific endonuclease subunit SLX4
著者Wan, B., Chen, Y., Wu, J., Liu, Y., Lei, M.
登録日2013-08-12
公開日2013-09-25
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献SLX4 Assembles a Telomere Maintenance Toolkit by Bridging Multiple Endonucleases with Telomeres
Cell Rep, 4, 2013
4QN3
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CRYSTAL STRUCTURE OF NEURAMINIDASE N7
分子名称:Neuraminidase, CALCIUM ION, N-ACETYL-D-GLUCOSAMINE, ...
著者Sun, X., Li, Q., Wu, Y., Liu, Y., Qi, J., Vavricka, C.J., Gao, G.F.
登録日2014-06-17
公開日2014-07-30
実験手法X-RAY DIFFRACTION (2.092 Å)
主引用文献Structure of influenza virus N7: the last piece of the neuraminidase "jigsaw" puzzle
J.Virol., 2014
4QN4
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CRYSTAL STRUCTURE OF NEURAMINIDASE N6
分子名称:Neuraminidase, CALCIUM ION, N-ACETYL-D-GLUCOSAMINE, ...
著者Sun, X., Li, Q., Wu, Y., Liu, Y., Qi, J., Vavricka, C.J., Gao, G.F.
登録日2014-06-17
公開日2014-07-30
最終更新日2014-08-06
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure of influenza virus N7: the last piece of the neuraminidase "jigsaw" puzzle
J.Virol., 2014
4QN5
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NEURAMINIDASE N5 BINDS LSTA AT THE SECOND SIA BINDING SITE
分子名称:Neuraminidase, CALCIUM ION, N-ACETYL-D-GLUCOSAMINE, ...
著者Sun, X., Li, Q., Wu, Y., Liu, Y., Qi, J., Vavricka, C.J., Gao, G.F.
登録日2014-06-17
公開日2014-07-30
最終更新日2014-08-06
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structure of influenza virus N7: the last piece of the neuraminidase "jigsaw" puzzle
J.Virol., 2014
4QN6
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CRYSTAL STRUCTURE OF NEURAMINIDASE N6 COMPLEXED WITH LANINAMIVIR
分子名称:Neuraminidase, CALCIUM ION, N-ACETYL-D-GLUCOSAMINE, ...
著者Sun, X., Li, Q., Wu, Y., Liu, Y., Qi, J., Vavricka, C.J., Gao, G.F.
登録日2014-06-17
公開日2014-07-30
最終更新日2014-08-06
実験手法X-RAY DIFFRACTION (1.945 Å)
主引用文献Structure of influenza virus N7: the last piece of the neuraminidase "jigsaw" puzzle
J.Virol., 2014
4QN7
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CRYSTAL STRUCTURE OF NEURAMNIDASE N7 COMPLEXED WITH OSELTAMIVIR
分子名称:Neuraminidase, CALCIUM ION, N-ACETYL-D-GLUCOSAMINE, ...
著者Sun, X., Li, Q., Wu, Y., Liu, Y., Qi, J., Vavricka, C.J., Gao, G.F.
登録日2014-06-17
公開日2014-07-30
最終更新日2014-08-06
実験手法X-RAY DIFFRACTION (2.302 Å)
主引用文献Structure of influenza virus N7: the last piece of the neuraminidase "jigsaw" puzzle
J.Virol., 2014
4W98
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ACINETOBACTER BAUMANNII SDF NDK
分子名称:Nucleoside diphosphate kinase
著者Hu, Y., Feng, F., Liang, H., Liu, Y.
登録日2014-08-27
公開日2015-06-17
実験手法X-RAY DIFFRACTION (1.43 Å)
主引用文献Structural and Functional Characterization of Acinetobacter baumannii Nucleoside Diphosphate Kinase
Prog.Biochem.Biophys., 42, 2015
4WBF
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ACINETOBACTER BAUMANNII SDF NDK
分子名称:Nucleoside diphosphate kinase
著者Hu, Y., Liu, Y.
登録日2014-09-03
公開日2015-06-17
実験手法X-RAY DIFFRACTION (2.64 Å)
主引用文献Structural and Functional Characterization of Acinetobacter baumannii Nucleoside Diphosphate Kinase
Prog.Biochem.Biophys., 42, 2015
4ZOU
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CRYSTAL STRUCTURE OF THE BTB DOMAIN OF SLX4
分子名称:Structure-specific endonuclease subunit SLX4
著者Wan, B., Chen, Y., Wu, J., Liu, Y., Lei, M.
登録日2015-05-07
公開日2016-05-04
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献The BTB domain is both a structural and functional pivot of the SLX4-nuclease complex
to be published
4ZUZ
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SIDC 1-871
分子名称:SidC
著者Luo, X., Wasilko, D.J., Liu, Y., Sun, J., Wu, X., Luo, Z.-Q., Mao, Y.
登録日2015-05-18
公開日2015-07-29
最終更新日2019-12-25
実験手法X-RAY DIFFRACTION (2.86 Å)
主引用文献Structure of the Legionella Virulence Factor, SidC Reveals a Unique PI(4)P-Specific Binding Domain Essential for Its Targeting to the Bacterial Phagosome.
Plos Pathog., 11, 2015
5C6H
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MCL-1 COMPLEXED WITH MULE
分子名称:Induced myeloid leukemia cell differentiation protein Mcl-1, Mule BH3 peptide from E3 ubiquitin-protein ligase HUWE1
著者Song, T., Wang, Z., Ji, F., Chai, G., Liu, Y., Li, X., Li, Z., Fan, Y., Zhang, Z.
登録日2015-06-23
公開日2016-08-03
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Structure of Mcl-1 complexed with Mule at 2.05 Angstroms resolution
To Be Published
5EJO
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CRYSTAL STRUCTURE OF THE WINGED HELIX DOMAIN IN CHROMATIN ASSEMBLY FACTOR 1 SUBUNIT P90
分子名称:Chromatin assembly factor 1 subunit p90
著者Zhang, K., Gao, Y., Li, J., Burgess, R., Han, J., Liang, H., Zhang, Z., Liu, Y.
登録日2015-11-02
公開日2016-03-16
最終更新日2016-07-06
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献A DNA binding winged helix domain in CAF-1 functions with PCNA to stabilize CAF-1 at replication forks
Nucleic Acids Res., 44, 2016
5F2E
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CRYSTAL STRUCTURE OF SMALL MOLECULE ARS-853 COVALENTLY BOUND TO K-RAS G12C
分子名称:GTPase KRas, MAGNESIUM ION, GLYCEROL, ...
著者Patricelli, M.P., Janes, M.R., Li, L.-S., Hansen, R., Peters, U., Kessler, L.V., Chen, Y., Kucharski, J.M., Feng, J., Ely, T., Chen, J.H., Firdaus, S.J., Babbar, A., Ren, P., Liu, Y.
登録日2015-12-01
公開日2016-01-13
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Selective Inhibition of Oncogenic KRAS Output with Small Molecules Targeting the Inactive State.
Cancer Discov, 6, 2016
5XF7
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CRYSTAL STRUCTURE OF HUMAN PROTEIN DISULFIDE ISOMERASE-LIKE PROTEIN OF THE TESTIS
分子名称:Protein disulfide-isomerase-like protein of the testis
著者Li, H., Li, J., Liu, Y., Liang, H.
登録日2017-04-08
公開日2017-12-13
最終更新日2018-02-07
実験手法X-RAY DIFFRACTION (2.381 Å)
主引用文献Crystal and solution structures of human protein-disulfide isomerase-like protein of the testis (PDILT) provide insight into its chaperone activity
J. Biol. Chem., 293, 2018
5ZUE
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GTP-BOUND, DOUBLE-STRANDED, CURVED FTSZ PROTOFILAMENT STRUCTURE
分子名称:Cell division protein FtsZ, GUANOSINE-5'-TRIPHOSPHATE
著者Guan, F., Yu, J., Yu, J., Liu, Y., Li, Y., Feng, X.H., Huang, K.C., Chang, Z., Ye, S.
登録日2018-05-07
公開日2018-07-04
最終更新日2018-07-25
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Lateral interactions between protofilaments of the bacterial tubulin homolog FtsZ are essential for cell division
Elife, 7, 2018
6B0V
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CRYSTAL STRUCTURE OF SMALL MOLECULE ARS-107 COVALENTLY BOUND TO K-RAS G12C
分子名称:GTPase KRas, CALCIUM ION, 1-[3-(4-{[(4,5-dichloro-2-hydroxyphenyl)amino]acetyl}piperazin-1-yl)azetidin-1-yl]propan-1-one, ...
著者Hansen, R., Peters, U., Babbar, A., Chen, Y., Feng, J., Janes, M.R., Li, L.-S., Ren, P., Liu, Y., Zarrinkar, P.P.
登録日2017-09-15
公開日2018-05-16
最終更新日2018-11-07
実験手法X-RAY DIFFRACTION (1.29 Å)
主引用文献The reactivity-driven biochemical mechanism of covalent KRASG12Cinhibitors.
Nat. Struct. Mol. Biol., 25, 2018
6B0Y
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CRYSTAL STRUCTURE OF SMALL MOLECULE ARS-917 COVALENTLY BOUND TO K-RAS G12C
分子名称:GTPase KRas, CALCIUM ION, 1-{4-[6-chloro-7-(2-fluorophenyl)quinazolin-4-yl]piperazin-1-yl}propan-1-one, ...
著者Hansen, R., Peters, U., Babbar, A., Chen, Y., Feng, J., Janes, M.R., Li, L.-S., Ren, P., Liu, Y., Zarrinkar, P.P.
登録日2017-09-15
公開日2018-05-16
最終更新日2018-11-07
実験手法X-RAY DIFFRACTION (1.43 Å)
主引用文献The reactivity-driven biochemical mechanism of covalent KRASG12Cinhibitors.
Nat. Struct. Mol. Biol., 25, 2018
6D2V
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APO STRUCTURE OF TERB, AN NADP DEPENDENT OXIDOREDUCTASE IN THE TERFESTATIN BIOSYNTHESIS PATHWAY
分子名称:TerB Oxidoreductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, THIOCYANATE ION, ...
著者Clinger, J.A., Elshahawi, S.I., Zhang, Y., Hall, R.P., Liu, Y., Thorson, J.S., Phillips Jr., G.N.
登録日2018-04-14
公開日2018-06-13
最終更新日2019-12-04
実験手法X-RAY DIFFRACTION (1.901 Å)
主引用文献Structure and Function of Terfestatin Biosynthesis Enzymes TerB and TerC
To Be Published
6D34
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APO CRYSTAL STRUCTURE OF TERC, A TERFESTATIN BIOSYNTHESIS ENZYME
分子名称:TerC, ISOPROPYL ALCOHOL
著者Clinger, J.A., Elshahawi, S.I., Zhang, Y., Hall, R.P., Liu, Y., Thorson, J.S., Phillips Jr., G.N.
登録日2018-04-14
公開日2018-06-13
最終更新日2019-12-04
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure and Function of Terfestatin Biosynthesis Enzymes TerB and TerC
To Be Published