Author results

5EJO
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CRYSTAL STRUCTURE OF THE WINGED HELIX DOMAIN IN CHROMATIN ASSEMBLY FACTOR 1 SUBUNIT P90
分子名称:Chromatin assembly factor 1 subunit p90
著者Zhang, K., Gao, Y., Li, J., Burgess, R., Han, J., Liang, H., Zhang, Z., Liu, Y.
登録日2015-11-02
公開日2016-03-16
最終更新日2016-07-06
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献A DNA binding winged helix domain in CAF-1 functions with PCNA to stabilize CAF-1 at replication forks
Nucleic Acids Res., 44, 2016
5F2E
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CRYSTAL STRUCTURE OF SMALL MOLECULE ARS-853 COVALENTLY BOUND TO K-RAS G12C
分子名称:GTPase KRas, MAGNESIUM ION, GLYCEROL, ...
著者Patricelli, M.P., Janes, M.R., Li, L.-S., Hansen, R., Peters, U., Kessler, L.V., Chen, Y., Kucharski, J.M., Feng, J., Ely, T., Chen, J.H., Firdaus, S.J., Babbar, A., Ren, P., Liu, Y.
登録日2015-12-01
公開日2016-01-13
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Selective Inhibition of Oncogenic KRAS Output with Small Molecules Targeting the Inactive State.
Cancer Discov, 6, 2016
5XF7
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CRYSTAL STRUCTURE OF HUMAN PROTEIN DISULFIDE ISOMERASE-LIKE PROTEIN OF THE TESTIS
分子名称:Protein disulfide-isomerase-like protein of the testis
著者Li, H., Li, J., Liu, Y., Liang, H.
登録日2017-04-08
公開日2017-12-13
最終更新日2018-02-07
実験手法X-RAY DIFFRACTION (2.381 Å)
主引用文献Crystal and solution structures of human protein-disulfide isomerase-like protein of the testis (PDILT) provide insight into its chaperone activity
J. Biol. Chem., 293, 2018
5ZUE
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GTP-BOUND, DOUBLE-STRANDED, CURVED FTSZ PROTOFILAMENT STRUCTURE
分子名称:Cell division protein FtsZ, GUANOSINE-5'-TRIPHOSPHATE
著者Guan, F., Yu, J., Yu, J., Liu, Y., Li, Y., Feng, X.H., Huang, K.C., Chang, Z., Ye, S.
登録日2018-05-07
公開日2018-07-04
最終更新日2018-07-25
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Lateral interactions between protofilaments of the bacterial tubulin homolog FtsZ are essential for cell division
Elife, 7, 2018
6B0V
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CRYSTAL STRUCTURE OF SMALL MOLECULE ARS-107 COVALENTLY BOUND TO K-RAS G12C
分子名称:GTPase KRas, CALCIUM ION, 1-[3-(4-{[(4,5-dichloro-2-hydroxyphenyl)amino]acetyl}piperazin-1-yl)azetidin-1-yl]propan-1-one, ...
著者Hansen, R., Peters, U., Babbar, A., Chen, Y., Feng, J., Janes, M.R., Li, L.-S., Ren, P., Liu, Y., Zarrinkar, P.P.
登録日2017-09-15
公開日2018-05-16
最終更新日2018-11-07
実験手法X-RAY DIFFRACTION (1.29 Å)
主引用文献The reactivity-driven biochemical mechanism of covalent KRASG12Cinhibitors.
Nat. Struct. Mol. Biol., 25, 2018
6B0Y
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CRYSTAL STRUCTURE OF SMALL MOLECULE ARS-917 COVALENTLY BOUND TO K-RAS G12C
分子名称:GTPase KRas, CALCIUM ION, 1-{4-[6-chloro-7-(2-fluorophenyl)quinazolin-4-yl]piperazin-1-yl}propan-1-one, ...
著者Hansen, R., Peters, U., Babbar, A., Chen, Y., Feng, J., Janes, M.R., Li, L.-S., Ren, P., Liu, Y., Zarrinkar, P.P.
登録日2017-09-15
公開日2018-05-16
最終更新日2018-11-07
実験手法X-RAY DIFFRACTION (1.43 Å)
主引用文献The reactivity-driven biochemical mechanism of covalent KRASG12Cinhibitors.
Nat. Struct. Mol. Biol., 25, 2018
6D2V
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APO STRUCTURE OF TERB, AN NADP DEPENDENT OXIDOREDUCTASE IN THE TERFESTATIN BIOSYNTHESIS PATHWAY
分子名称:TerB Oxidoreductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, THIOCYANATE ION, ...
著者Clinger, J.A., Elshahawi, S.I., Zhang, Y., Hall, R.P., Liu, Y., Thorson, J.S., Phillips Jr., G.N.
登録日2018-04-14
公開日2018-06-13
実験手法X-RAY DIFFRACTION (1.901 Å)
主引用文献Structure and Function of Terfestatin Biosynthesis Enzymes TerB and TerC
To Be Published
6D34
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APO CRYSTAL STRUCTURE OF TERC, A TERFESTATIN BIOSYNTHESIS ENZYME
分子名称:TerC, ISOPROPYL ALCOHOL
著者Clinger, J.A., Elshahawi, S.I., Zhang, Y., Hall, R.P., Liu, Y., Thorson, J.S., Phillips Jr., G.N.
登録日2018-04-14
公開日2018-06-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure and Function of Terfestatin Biosynthesis Enzymes TerB and TerC
To Be Published
6NN3
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STRUCTURE OF PARVOVIRUS B19 DECORATED WITH FAB MOLECULES FROM A HUMAN ANTIBODY
分子名称:VP2 of B19 parvovirus, Fab monoclonal antibody 860-55D, heavy chain, ...
著者Rossmann, M.G., Sun, Y., Klose, T., Liu, Y.
登録日2019-01-14
公開日2019-02-13
最終更新日2019-05-01
実験手法ELECTRON MICROSCOPY (3.22 Å)
主引用文献Structure of Parvovirus B19 Decorated by Fabs from a Human Antibody.
J. Virol., 93, 2019
1P5J
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CRYSTAL STRUCTURE ANALYSIS OF HUMAN SERINE DEHYDRATASE
分子名称:L-serine dehydratase, PYRIDOXAL-5'-PHOSPHATE
著者Sun, L., Liu, Y., Rao, Z.
登録日2003-04-27
公開日2004-06-01
最終更新日2018-07-04
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystallization and preliminary crystallographic analysis of human serine dehydratase.
Acta Crystallogr.,Sect.D, 59, 2003
1P5T
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CRYSTAL STRUCTURE OF DOK1 PTB DOMAIN
分子名称:Docking protein 1
著者Shi, N., Ye, S., Liu, Y., Zhou, W., Ding, Y., Lou, Z., Qiang, B., Yuan, J., Rao, Z.
登録日2003-04-28
公開日2004-02-17
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structural Basis for the Specific Recognition of RET by the Dok1 Phosphotyrosine Binding Domain
J.BIOL.CHEM., 279, 2004
1UEF
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CRYSTAL STRUCTURE OF DOK1 PTB DOMAIN COMPLEX
分子名称:Docking protein 1, 13-mer peptide from Proto-oncogene tyrosine-protein kinase receptor ret
著者Shi, N., Ye, S., Liu, Y., Zhou, W., Ding, Y., Lou, Z., Qiang, B., Yan, J., Rao, Z.
登録日2003-05-14
公開日2004-05-25
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural Basis for the Specific Recognition of RET by the Dok1 Phosphotyrosine Binding Domain
J.Biol.Chem., 279, 2004
2GNC
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CRYSTAL STRUCTURE OF SRGAP1 SH3 DOMAIN IN THE SLIT-ROBO SIGNALING PATHWAY
分子名称:SLIT-ROBO Rho GTPase-activating protein 1
著者Li, X., Liu, Y., Gao, F., Bartlam, M., Wu, J.Y., Rao, Z.
登録日2006-04-10
公開日2006-07-18
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural Basis of Robo Proline-rich Motif Recognition by the srGAP1 Src Homology 3 Domain in the Slit-Robo Signaling Pathway
J.Biol.Chem., 281, 2006
3FVM
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CRYSTAL STRUCTURE OF STEPTOCOCCUS SUIS MANNONATE DEHYDRATASE WITH METAL MN++
分子名称:Mannonate dehydratase, MANGANESE (II) ION
著者Peng, H., Zhang, Q.J., Gao, F., Liu, Y., Gao, F.G.
登録日2009-01-16
公開日2009-09-01
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal structures of Streptococcus suis mannonate dehydratase (ManD) and its complex with substrate: genetic and biochemical evidence for a catalytic mechanism
J.Bacteriol., 191, 2009
4NRM
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CRYSTAL STRUCTURE OF HUMAN ALKBH5 IN COMPLEX WITH CITRATE AND ACETATE
分子名称:RNA demethylase ALKBH5, CITRATE ANION, ACETATE ION
著者Feng, C., Chen, Z., Liu, Y.
登録日2013-11-27
公開日2014-03-19
最終更新日2015-10-21
実験手法X-RAY DIFFRACTION (2.17 Å)
主引用文献Crystal structures of the human RNA demethylase Alkbh5 reveal basis for substrate recognition
J.Biol.Chem., 289, 2014
4NRO
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CRYSTAL STRUCTURE OF HUMAN ALKBH5 IN COMPLEX WITH ALPHA-KETOGLUTARATE
分子名称:RNA demethylase ALKBH5, MANGANESE (II) ION, 2-OXOGLUTARIC ACID
著者Feng, C., Chen, Z., Liu, Y.
登録日2013-11-27
公開日2014-03-19
最終更新日2015-10-21
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structures of the human RNA demethylase Alkbh5 reveal basis for substrate recognition
J.Biol.Chem., 289, 2014
4NRP
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CRYSTAL STRUCTURE OF HUMAN ALKBH5 IN COMPLEX WITH N-OXALYLGLYCINE
分子名称:RNA demethylase ALKBH5, MANGANESE (II) ION, N-OXALYLGLYCINE
著者Feng, C., Chen, Z., Liu, Y.
登録日2013-11-27
公開日2014-03-19
最終更新日2015-10-21
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structures of the human RNA demethylase Alkbh5 reveal basis for substrate recognition
J.Biol.Chem., 289, 2014
4NRQ
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CRYSTAL STRUCTURE OF HUMAN ALKBH5 IN COMPLEX WITH PYRIDINE-2,4-DICARBOXYLATE
分子名称:RNA demethylase ALKBH5, PYRIDINE-2,4-DICARBOXYLIC ACID, MANGANESE (II) ION
著者Feng, C., Chen, Z., Liu, Y.
登録日2013-11-27
公開日2014-03-19
最終更新日2015-10-21
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structures of the human RNA demethylase Alkbh5 reveal basis for substrate recognition
J.Biol.Chem., 289, 2014
4O7X
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CRYSTAL STRUCTURE OF HUMAN ALKBH5 IN COMPLEX WITH MN2+
分子名称:RNA demethylase ALKBH5, MANGANESE (II) ION
著者Feng, C., Chen, Z., Liu, Y.
登録日2013-12-26
公開日2014-03-19
最終更新日2015-10-21
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Crystal structures of the human RNA demethylase Alkbh5 reveal basis for substrate recognition
J.Biol.Chem., 289, 2014
4RZF
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CRYSTAL STRUCTURE ANALYSIS OF THE NUR77 LIGAND BINDING DOMAIN, S441W MUTANT
分子名称:Nuclear receptor subfamily 4 group A member 1, GLYCEROL
著者Li, F., Tian, X., Li, A., Li, L., Liu, Y., Chen, H., Wu, Q., Lin, T.
登録日2014-12-21
公開日2015-03-18
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Impeding the interaction between Nur77 and p38 reduces LPS-induced inflammation.
Nat.Chem.Biol., 11, 2015
4RZG
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CRYSTAL STRUCTURE ANALYSIS OF THE DNPA-BOUNDED NUR77 LIGAND BINDING DOMAIN
分子名称:Nuclear receptor subfamily 4 group A member 1, GLYCEROL, pentyl (3,5-dihydroxy-2-nonanoylphenyl)acetate
著者Li, F., Tian, X., Li, A., Li, L., Liu, Y., Chen, H., Wu, Q., Lin, T.
登録日2014-12-21
公開日2015-03-18
最終更新日2015-05-06
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Impeding the interaction between Nur77 and p38 reduces LPS-induced inflammation.
Nat.Chem.Biol., 11, 2015
5GT5
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STRUCTURAL BASIS OF THE SPECIFIC ACTIVITY AND THERMOSTABILITY OF PECTATE LYASE (PELN) FROM PAENIBACILLUS SP. 0602
分子名称:Pectate lyase
著者Zhou, Z.P., Liu, Y., Song, J.N.
登録日2016-08-18
公開日2017-10-25
実験手法X-RAY DIFFRACTION (1.449 Å)
主引用文献Structure-based engineering of a pectate lyase with improved specific activity for ramie degumming.
Appl. Microbiol. Biotechnol., 101, 2017
5YLC
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CRYSTAL STRUCTURE OF MCR-1 CATALYTIC DOMAIN
分子名称:Probable phosphatidylethanolamine transferase Mcr-1, ZINC ION
著者Wei, P.C., Song, G.J., Shi, M.Y., Zhou, Y.F., Liu, Y., Lei, J., Chen, P., Yin, L.
登録日2017-10-17
公開日2017-11-08
最終更新日2018-03-07
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Substrate analog interaction with MCR-1 offers insight into the rising threat of the plasmid-mediated transferable colistin resistance.
FASEB J., 32, 2018
5YLE
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MCR-1 COMPLEX WITH ETHANOLAMINE (ETA)
分子名称:Probable phosphatidylethanolamine transferase Mcr-1, ETHANOLAMINE, ZINC ION
著者Wei, P.C., Song, G.J., Shi, M.Y., Zhou, Y.F., Liu, Y., Lei, J., Chen, P., Yin, L.
登録日2017-10-17
公開日2017-11-08
最終更新日2018-03-07
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Substrate analog interaction with MCR-1 offers insight into the rising threat of the plasmid-mediated transferable colistin resistance.
FASEB J., 32, 2018
5YLF
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MCR-1 COMPLEX WITH D-GLUCOSE
分子名称:Probable phosphatidylethanolamine transferase Mcr-1, BETA-D-GLUCOSE, ZINC ION
著者Wei, P.C., Song, G.J., Shi, M.Y., Zhou, Y.F., Liu, Y., Lei, J., Chen, P., Yin, L.
登録日2017-10-17
公開日2017-11-08
最終更新日2018-03-07
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Substrate analog interaction with MCR-1 offers insight into the rising threat of the plasmid-mediated transferable colistin resistance.
FASEB J., 32, 2018