Author results

3SM3
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CRYSTAL STRUCTURE OF SAM-DEPENDENT METHYLTRANSFERASES Q8PUK2_METMA FROM METHANOSARCINA MAZEI. NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET MAR262.
Descriptor:SAM-dependent methyltransferases, CALCIUM ION, DI(HYDROXYETHYL)ETHER
Authors:Vorobiev, S., Neely, H., Seetharaman, J., Snyder, A., Patel, P., Xiao, R., Ciccosanti, C., Everett, J.K., Nair, R., Acton, T.B., Rost, B., Montelione, G.T., Hunt, J.F., Tong, L., Northeast Structural Genomics Consortium (NESG)
Deposit date:2011-06-27
Release date:2011-07-20
Method:X-RAY DIFFRACTION (2.197 Å)
Cite:Crystal Structure of SAM-dependent methyltransferases Q8PUK2_METMA from Methanosarcina mazei.
To be Published, 2009
3SXW
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CRYSTAL STRUCTURE OF ENGINEERED PROTEIN. NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET OR69.
Descriptor:Glucose-6-phosphate isomerase
Authors:Vorobiev, S., Su, M., Nivon, L., Seetharaman, J., Patel, P., Xiao, R., Maglaqui, M., Ciccosanti, C., Baker, D., Everett, J.K., Nair, R., Acton, T.B., Rost, B., Montelione, G.T., Hunt, J.F., Tong, L., Northeast Structural Genomics Consortium (NESG)
Deposit date:2011-07-15
Release date:2011-08-03
Method:X-RAY DIFFRACTION (1.801 Å)
Cite:Crystal Structure of Engineered Protein. Northeast Structural Genomics Consortium Target OR69.
To be Published
3SY1
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CRYSTAL STRUCTURE OF ENGINEERED PROTEIN. NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET OR70
Descriptor:UPF0001 protein yggS, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ACETIC ACID
Authors:Vorobiev, S., Su, M., Nivon, L., Seetharaman, J., Sahdev, S., Xiao, R., Ciccosanti, C., Maglaqui, M., Baker, D., Everett, J.K., Nair, R., Acton, T.B., Rost, B., Montelione, G.T., Hunt, J.F., Tong, L., Northeast Structural Genomics Consortium (NESG)
Deposit date:2011-07-15
Release date:2011-08-03
Method:X-RAY DIFFRACTION (1.465 Å)
Cite:Crystal Structure of Engineered Protein. Northeast Structural Genomics Consortium Target OR70
To be Published
3U02
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CRYSTAL STRUCTURE OF THE TRNA MODIFIER TIAS FROM PYROCOCCUS FURIOSUS, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET PFR225
Descriptor:Putative transcription-associated protein TFIIS, SULFATE ION, CITRIC ACID, ...
Authors:Kuzin, A., Lew, S., Seetharaman, J., Sahdev, S., Xiao, R., Ciccosanti, C., Wang, H., Everett, J.K., Nair, R., Acton, T.B., Rost, B., Montelione, G.T., Tong, L., Hunt, J.F., Northeast Structural Genomics Consortium (NESG)
Deposit date:2011-09-28
Release date:2011-11-02
Method:X-RAY DIFFRACTION (2.399 Å)
Cite:Crystal Structure of the tRNA modifier TiaS from Pyrococcus furiosus, Northeast Structural Genomics Consortium Target PfR225
To be Published
3U07
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CRYSTAL STRUCTURE OF THE VPA0106 PROTEIN FROM VIBRIO PARAHAEMOLYTICUS. NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET VPR106.
Descriptor:uncharacterized protein VPA0106
Authors:Vorobiev, S., Neely, H., Seetharaman, J., Patel, P., Xiao, R., Ciccosanti, C., Wang, H., Everett, J.K., Nair, R., Acton, T.B., Rost, B., Montelione, G.T., Tong, L., Hunt, J.F., Northeast Structural Genomics Consortium (NESG)
Deposit date:2011-09-28
Release date:2011-10-12
Method:X-RAY DIFFRACTION (2.083 Å)
Cite:Crystal Structure of the VPA0106 protein from Vibrio parahaemolyticus.
To be Published
3U4T
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CRYSTAL STRUCTURE OF THE C-TERMINAL PART OF THE TPR REPEAT-CONTAINING PROTEIN Q11TI6_CYTH3 FROM CYTOPHAGA HUTCHINSONII. NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET CHR11B.
Descriptor:TPR repeat-containing protein
Authors:Vorobiev, S., Neely, H., Chen, Y., Seetharaman, J., Patel, P., Xiao, R., Ciccosanti, C., Maglaqui, M., Everett, J.K., Nair, R., Acton, T.B., Rost, B., Montelione, G.T., Tong, L., Hunt, J.F., Northeast Structural Genomics Consortium (NESG)
Deposit date:2011-10-10
Release date:2011-10-19
Method:X-RAY DIFFRACTION (2.282 Å)
Cite:Crystal Structure of the C-terminal part of the TPR repeat-containing protein Q11TI6_CYTH3 from Cytophaga hutchinsonii.
To be Published
3UAK
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CRYSTAL STRUCTURE OF DE NOVO DESIGNED CYSTEINE ESTERASE ECH14, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET OR54
Descriptor:De Novo designed cysteine esterase ECH14
Authors:Kuzin, A., Su, M., Seetharaman, J., Sahdev, S., Xiao, R., Ciccosanti, C., Richter, F., Everett, J.K., Nair, R., Acton, T.B., Rost, B., Baker, D., Montelione, G.T., Hunt, J.F., Tong, L., Northeast Structural Genomics Consortium (NESG)
Deposit date:2011-10-21
Release date:2011-12-07
Last modified:2013-12-11
Method:X-RAY DIFFRACTION (3.232 Å)
Cite:Computational design of catalytic dyads and oxyanion holes for ester hydrolysis.
J.Am.Chem.Soc., 134, 2012
3UF1
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CRYSTAL STRUCTURE OF VIMENTIN (FRAGMENT 144-251) FROM HOMO SAPIENS, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET HR4796B
Descriptor:Vimentin
Authors:Kuzin, A., Abashidze, M., Vorobiev, S.M., Patel, P., Xiao, R., Ciccosanti, C., Shastry, R., Everett, J.K., Nair, R., Acton, T.B., Rost, B., Montelione, G.T., Tong, L., Hunt, J.F., Northeast Structural Genomics Consortium (NESG)
Deposit date:2011-10-31
Release date:2011-11-30
Last modified:2013-04-24
Method:X-RAY DIFFRACTION (2.81 Å)
Cite:The structure of vimentin linker 1 and rod 1B domains characterized by site-directed spin-labeling electron paramagnetic resonance (SDSL-EPR) and X-ray crystallography.
J.Biol.Chem., 287, 2012
4DLH
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CRYSTAL STRUCTURE OF THE PROTEIN Q9HRE7 FROM HALOBACTERIUM SALINARIUM AT THE RESOLUTION 1.9A, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM (NESG) TARGET HSR50
Descriptor:uncharacterized protein
Authors:Kuzin, A., Chen, Y., Seetharaman, J., Mao, M., Xiao, R., Ciccosanti, C., Zhao, L., Everett, J.K., Nair, R., Acton, T.B., Rost, B., Montelione, G.T., Hunt, J.F., Tong, L., Northeast Structural Genomics Consortium (NESG)
Deposit date:2012-02-06
Release date:2012-02-15
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Northeast Structural Genomics Consortium Target HsR50
To be Published
4F9K
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CRYSTAL STRUCTURE OF HUMAN CAMP-DEPENDENT PROTEIN KINASE TYPE I-BETA REGULATORY SUBUNIT (FRAGMENT 11-73), NORTHEAST STRUCTURAL GENOMICS CONSORTIUM (NESG) TARGET HR8613A
Descriptor:cAMP-dependent protein kinase type I-beta regulatory subunit
Authors:Kuzin, A., Lew, S., Seetharaman, J., Maglaqui, M., Xiao, R., Kohan, E., Shastry, R., Everett, J.K., Acton, T.B., Montelione, G.T., Hunt, J.F., Tong, L., Northeast Structural Genomics Consortium (NESG)
Deposit date:2012-05-18
Release date:2012-06-06
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal Structure of human cAMP-dependent protein kinase type I-beta regulatory subunit (fragment 11-73), Northeast Structural Genomics Consortium (NESG) Target HR8613A
To be Published
4FEK
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CRYSTAL STRUCTURE OF PUTATIVE DIFLAVIN FLAVOPROTEIN A 5 (FRAGMENT 1-254) FROM NOSTOC SP. PCC 7120, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET NSR435A , NORTHEAST STRUCTURAL GENOMICS CONSORTIUM (NESG) TARGET NSR435A
Descriptor:Putative diflavin flavoprotein A 5, DI(HYDROXYETHYL)ETHER, CHLORIDE ION, ...
Authors:Kuzin, A., Abashidze, M., Seetharaman, J., Janjua, J., Xiao, R., Foote, E.L., Ciccosanti, C., Wang, H., Everett, J.K., Nair, R., Acton, T.B., Rost, B., Montelione, G.T., Hunt, J.F., Tong, L., Northeast Structural Genomics Consortium (NESG)
Deposit date:2012-05-30
Release date:2012-07-11
Method:X-RAY DIFFRACTION (2 Å)
Cite:Northeast Structural Genomics Consortium Target NsR435A
To be Published
4FLE
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CRYSTAL STRUCTURE OF THE ESTERASE YQIA (YE3661) FROM YERSINIA ENTEROCOLITICA, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET YER85
Descriptor:esterase
Authors:Forouhar, F., Lew, S., Seetharaman, J., Shastry, R., Kohan, E., Maglaqui, M., Mao, L., Xiao, R., Acton, T.B., Everett, J.K., Montelione, G.T., Tong, L., Hunt, J.F., Northeast Structural Genomics Consortium, Northeast Structural Genomics Consortium (NESG)
Deposit date:2012-06-14
Release date:2012-08-08
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of the esterase YqiA (YE3661) from Yersinia enterocolitica, Northeast Structural Genomics Consortium Target YeR85 (CASP Target)
To be Published
4HHU
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CRYSTAL STRUCTURE OF ENGINEERED PROTEIN. NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET OR280.
Descriptor:OR280, 3,6,9,12,15-PENTAOXAHEPTADECAN-1-OL, TETRAETHYLENE GLYCOL
Authors:Vorobiev, S., Lew, S., Lin, Y.-R., Seetharaman, J., Castelllanos, J., Maglaqui, M., Xiao, R., Lee, D., Koga, N., Koga, R., Everett, J.K., Acton, T.B., Baker, D., Montelione, G.T., Tong, L., Hunt, J.F., Northeast Structural Genomics Consortium (NESG)
Deposit date:2012-10-10
Release date:2012-10-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of Engineered Protein OR280.
To be Published
4J29
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CRYSTAL STRUCTURE OF ENGINEERED PROTEIN. NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET OR258.
Descriptor:Engineered Protein OR258
Authors:Vorobiev, S., Su, M., Koga, R., Seetharaman, J., Koga, N., Mao, L., Xiao, R., Kohan, E., Castelllanos, J., Everett, J.K., Acton, T.B., Baker, D., Montelione, G.T., Tong, L., Hunt, J.F., Northeast Structural Genomics Consortium (NESG)
Deposit date:2013-02-04
Release date:2013-03-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structure of Engineered Protein OR258.
To be Published
4L1J
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THREE DIMENSIONAL STRUCTURE OF MUTANT D143A OF HUMAN HD DOMAIN-CONTAINING PROTEIN 2, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM (NESG) TARGET HR6723
Descriptor:HD domain-containing protein 2, HD domain-containing protein 2 (Phosphorylate), DI(HYDROXYETHYL)ETHER, ...
Authors:Kuzin, A., Su, M., Yakunin, A., Beloglazova, O., Seetharaman, J., Maglaqui, M., Xiao, R., Lee, D., Brown, G., Flick, R., Everett, J.K., Acton, T.B., Montelione, G.T., Hunt, J.F., Tong, L., Northeast Structural Genomics Consortium (NESG)
Deposit date:2013-06-03
Release date:2013-06-19
Last modified:2013-12-25
Method:X-RAY DIFFRACTION (1.824 Å)
Cite:Three dimensional structure of mutant D143A of human HD domain-containing protein 2, Northeast Structural Genomics Consortium (NESG) Target HR6723
To be Published
4L7E
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THREE DIMENSIONAL STRUCTURE OF MUTANT D78A OF HUMAN HD DOMAIN-CONTAINING PROTEIN 2, GENOMICS CONSORTIUM (NESG) TARGET HR6723
Descriptor:HD domain-containing protein 2, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Kuzin, A., Su, M., Yakunin, A., Beloglazova, N., Seetharaman, J., Maglaqui, M., Xiao, R., Lee, D., Brown, G., Flick, R., Everett, J.K., Acton, T.B., Montelione, G.T., Hunt, J.F., Tong, L., Northeast Structural Genomics Consortium (NESG)
Deposit date:2013-06-13
Release date:2013-07-24
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.229 Å)
Cite:Northeast Structural Genomics Consortium Target HR6723
To be Published
4L7W
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CRYSTAL STRUCTURE MUTANT H77A OF HUMAN HD DOMAIN-CONTAINING PROTEIN 2, GENOMICS CONSORTIUM (NESG) TARGET HR6723
Descriptor:HD domain-containing protein 2, MAGNESIUM ION
Authors:Kuzin, A., Su, M., Yakunin, A., Beloglazova, N., Seetharaman, J., Maglaqui, M., Xiao, R., Lee, D., Brown, G., Flick, R., Everett, J.K., Acton, T.B., Montelione, G.T., Hunt, J.F., Tong, L., Northeast Structural Genomics Consortium (NESG)
Deposit date:2013-06-14
Release date:2013-07-03
Method:X-RAY DIFFRACTION (2.305 Å)
Cite:Northeast Structural Genomics Consortium Target HR6723
To be Published
4NE7
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CRYSTAL STRUCTURE OF ENGINEERED KUMAMOLISIN-AS FROM ALICYCLOBACILLUS SENDAIENSIS, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM (NESG) TARGET OR367
Descriptor:Kumamolisin-As, ZINC ION
Authors:Guan, R., Pultz, I.S., Siegel, J.B., Seetharaman, J., Kornhaber, G., Maglaqui, M., Mao, L., Xiao, R., Everett, J.K., Baker, D., Montelione, G.T., Northeast Structural Genomics Consortium (NESG)
Deposit date:2013-10-28
Release date:2013-11-20
Method:X-RAY DIFFRACTION (2.497 Å)
Cite:Northeast Structural Genomics Consortium Target OR367
To be Published
4NZG
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CRYSTAL STRUCTURE OF THE N-TERMINAL DOMAIN OF MOLONEY MURINE LEUKEMIA VIRUS INTEGRASE, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET OR3
Descriptor:Integrase p46, ZINC ION, ACETATE ION, ...
Authors:Guan, R., Jiang, M., Janjua, H., Maglaqui, M., Zhao, L., Xiao, R., Acton, T.B., Everett, J.K., Roth, M., Montelione, G.T., Northeast Structural Genomics Consortium (NESG)
Deposit date:2013-12-12
Release date:2014-02-05
Last modified:2017-02-22
Method:X-RAY DIFFRACTION (2.152 Å)
Cite:X-ray crystal structure of the N-terminal region of Moloney murine leukemia virus integrase and its implications for viral DNA recognition.
Proteins, 2017
4PY9
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CRYSTAL STRUCTURE OF AN EXOPOLYPHOSPHATASE-RELATED PROTEIN FROM BACTEROIDES FRAGILIS. NORTHEAST STRUCTURAL GENOMICS TARGET BFR192
Descriptor:Putative exopolyphosphatase-related protein, PHOSPHATE ION, SODIUM ION
Authors:Seetharaman, J., Abashidze, M., Wang, H., Janjua, H., Foote, E.L., Xiao, R., Nair, R., Everett, J.K., Acton, T.B., Rost, B., Montelione, G.T., Tong, L., Hunt, J.F., Northeast Structural Genomics Consortium (NESG)
Deposit date:2014-03-26
Release date:2014-06-25
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Crystal structure of an exopolyphosphatase-related protein from Bacteroides Fragilis. Northeast Structural Genomics target BFR192
To be Published
4R80
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CRYSTAL STRUCTURE OF A DE NOVO DESIGNED BETA SHEET PROTEIN, CYSTATIN FOLD, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM (NESG) TARGET OR486
Descriptor:OR486
Authors:Guan, R., Marcos, E., O'Connell, P., Seetharaman, J., Janjua, H., Xiao, R., Maglaqui, M., Acton, T.B., Everett, J.K., Baker, D., Montelione, G.T., Northeast Structural Genomics Consortium (NESG)
Deposit date:2014-08-29
Release date:2014-09-24
Method:X-RAY DIFFRACTION (2.445 Å)
Cite:Crystal Structure of an engineered protein with denovo beta sheet design, Northeast Structural Genomics Consortium (NESG) Target OR486
To be Published
4ZEQ
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CRYSTAL STRUCTURE OF HUMAN BFL-1 IN COMPLEX WITH TBID BH3 PEPTIDE, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET HX9247
Descriptor:Bcl-2-related protein A1, BH3-interacting domain death agonist
Authors:Guan, R., Xiao, R., Mao, L., Montelione, G.T., Northeast Structural Genomics Consortium (NESG)
Deposit date:2015-04-20
Release date:2015-05-06
Last modified:2016-07-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structure of human BFL-1 in complex with tBid BH3 peptide
To Be Published
6E12
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CRYSTAL STRUCTURE OF THE ALR8543 PROTEIN IN COMPLEX WITH OLEIC ACID AND MAGNESIUM ION FROM NOSTOC SP. PCC 7120, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET NSR141
Descriptor:Alr8543 protein, OLEIC ACID, MAGNESIUM ION, ...
Authors:Forouhar, F., Neely, H., Seetharaman, J., Xiao, R., Ciccosanti, C., Patel, D., Belote, R.L., Everett, J.K., Nair, R., Acton, T.B., Rost, B., Montelione, G.T., Tong, L., Hunt, J.F., Northeast Structural Genomics Consortium (NESG)
Deposit date:2018-07-09
Release date:2018-07-25
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Structure of the Alr8543 protein in complex with Oleic Acid and magnesium ion from Nostoc sp. PCC 7120, Northeast Structural Genomics Consortium Target NsR141
To Be Published
1MZG
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X-RAY STRUCTURE OF SUFE FROM E.COLI NORTHEAST STRUCTURAL GENOMICS (NESG) CONSORTIUM TARGET ER30
Descriptor:SufE Protein
Authors:Kuzin, A., Edstrom, W.C., Xiao, R., Acton, T.B., Rost, B., Tong, L., Montelione, G.T., Hunt, J.F., Northeast Structural Genomics Consortium (NESG)
Deposit date:2002-10-07
Release date:2003-01-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:The SufE sulfur-acceptor protein contains a conserved core structure that mediates interdomain interactions in a variety of redox protein complexes
J.Mol.Biol., 344, 2004
1NXU
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CRYSTAL STRUCTURE OF E. COLI HYPOTHETICAL OXIDOREDUCTASE YIAK NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET ER82.
Descriptor:Hypothetical oxidoreductase yiaK, SULFATE ION
Authors:Forouhar, F., Lee, I., Benach, J., Kulkarni, K., Xiao, R., Acton, T.B., Shastry, R., Rost, B., Montelione, G.T., Tong, L., Northeast Structural Genomics Consortium (NESG)
Deposit date:2003-02-11
Release date:2003-03-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A Novel NAD-binding Protein Revealed by the Crystal Structure of 2,3-Diketo-L-gulonate Reductase (YiaK).
J.Biol.Chem., 279, 2004