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3IEW
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CRYSTAL STRUCTURE OF 2C-METHYL-D-ERYTHRITOL 2,4-CYCLODIPHOSPHATE SYNTHASE FROM BURKHOLDERIA PSEUDOMALLEI WITH BOUND CTP AND CDP
Descriptor:2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, ZINC ION, CYTIDINE-5'-DIPHOSPHATE, ...
Authors:Staker, B.L., Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2009-07-23
Release date:2009-08-18
Last modified:2013-10-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Leveraging structure determination with fragment screening for infectious disease drug targets: MECP synthase from Burkholderia pseudomallei.
J Struct Funct Genomics, 12, 2011
3IKE
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CRYSTAL STRUCTURE OF 2C-METHYL-D-ERYTHRITOL 2,4-CYCLODIPHOSPHATE SYNTHASE FROM BURKHOLDERIA PSEUDOMALLEI WITH CYTOSINE
Descriptor:2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, ZINC ION, 6-AMINOPYRIMIDIN-2(1H)-ONE, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2009-08-05
Release date:2009-08-18
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Leveraging structure determination with fragment screening for infectious disease drug targets: MECP synthase from Burkholderia pseudomallei.
J Struct Funct Genomics, 12, 2011
3IKF
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CRYSTAL STRUCTURE OF 2C-METHYL-D-ERYTHRITOL 2,4-CYCLODIPHOSPHATE SYNTHASE FROM BURKHOLDERIA PSEUDOMALLEI WITH FOL FRAGMENT 717, IMIDAZO[2,,1-B][1,3]THIAZOL-6-YLMETHANOL
Descriptor:2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, ZINC ION, imidazo[2,1-b][1,3]thiazol-6-ylmethanol, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2009-08-05
Release date:2009-08-18
Last modified:2013-12-11
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Leveraging structure determination with fragment screening for infectious disease drug targets: MECP synthase from Burkholderia pseudomallei.
J Struct Funct Genomics, 12, 2011
3JVH
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CRYSTAL STRUCTURE OF 2C-METHYL-D-ERYTHRITOL-2,4-CYCLODIPHOSPHATE SYNTHASE FROM BURKHOLDERIA PSEUDOMALLEI WITH FOL FRAGMENT 8395
Descriptor:2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, ZINC ION, 5-[(pyridin-3-ylmethyl)amino]-1H-pyrazole-4-carboxamide, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2009-09-16
Release date:2009-09-29
Last modified:2013-12-11
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Leveraging structure determination with fragment screening for infectious disease drug targets: MECP synthase from Burkholderia pseudomallei.
J Struct Funct Genomics, 12, 2011
3K14
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CO-CRYSTAL STRUCTURE OF 2C-METHYL-D-ERYTHRITOL 2,4-CYCLODIPHOSPHATE SYNTHASE FROM BURKHOLDERIA PSEUDOMALLEI WITH FOL FRAGMENT 535, ETHYL 3-METHYL-5,6-DIHYDROIMIDAZO[2,1-B][1,3]THIAZOLE-2-CARBOXYLATE
Descriptor:2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, ZINC ION, ethyl 3-methyl-5,6-dihydroimidazo[2,1-b][1,3]thiazole-2-carboxylate, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2009-09-25
Release date:2009-10-06
Last modified:2013-10-30
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Leveraging structure determination with fragment screening for infectious disease drug targets: MECP synthase from Burkholderia pseudomallei.
J Struct Funct Genomics, 12, 2011
3K2X
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CRYSTAL STRUCTURE OF 2C-METHYL-D-ERYTHRITOL 2,4-CYCLODIPHOSPHATE SYNTHASE FROM BURKHOLDERIA PSEUDOMALLEI IN COMPLEX WITH 5'-IODO-CYTOSINE
Descriptor:2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, ZINC ION, 5'-deoxy-5'-iodocytidine, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2009-09-30
Release date:2009-10-13
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Leveraging structure determination with fragment screening for infectious disease drug targets: MECP synthase from Burkholderia pseudomallei.
J Struct Funct Genomics, 12, 2011
3K9W
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CRYSTAL STRUCTURE OF PHOSPHOPANTETHEINE ADENYLYLTRANSFERASE FROM BURKHOLDERIA PSEUDOMALLEI WITH HYDROLYZED 3'-DEPHOSPHO COENZYME A
Descriptor:Phosphopantetheine adenylyltransferase, 4'-diphospho pantetheine, ADENINE, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2009-10-16
Release date:2009-11-03
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structures of phosphopantetheine adenylyltransferase from Burkholderia pseudomallei.
Acta Crystallogr.,Sect.F, 67, 2011
3MBM
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CRYSTAL STRUCTURE OF 2C-METHYL-D-ERYTHRITOL 2,4-CYCLODIPHOSPHATE SYNTHASE FROM BURKHOLDERIA PSEUDOMALLEI WITH CYTOSINE AND FOL FRAGMENT 717, IMIDAZO[2,1-B][1,3]THIAZOL-6-YLMETHANOL
Descriptor:2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, ZINC ION, 6-AMINOPYRIMIDIN-2(1H)-ONE, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2010-03-25
Release date:2010-04-07
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Leveraging structure determination with fragment screening for infectious disease drug targets: MECP synthase from Burkholderia pseudomallei.
J Struct Funct Genomics, 12, 2011
3MD0
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CRYSTAL STRUCTURE OF ARGININE/ORNITHINE TRANSPORT SYSTEM ATPASE FROM MYCOBACTERIUM TUBERCULOSIS BOUND TO GDP (A RAS-LIKE GTPASE SUPERFAMILY PROTEIN)
Descriptor:Arginine/ornithine transport system ATPase, GUANOSINE-5'-DIPHOSPHATE, UNKNOWN ATOM OR ION
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2010-03-29
Release date:2010-04-21
Last modified:2015-06-03
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Crystal structures of Mycobacterial MeaB and MMAA-like GTPases.
J.Struct.Funct.Genom., 16, 2015
3NFW
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CRYSTAL STRUCTURE OF NITRILOTRIACETATE MONOOXYGENASE COMPONENT B (A0R521 HOMOLOG) FROM MYCOBACTERIUM THERMORESISTIBILE
Descriptor:Flavin reductase-like, FMN-binding protein, GLYCEROL
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2010-06-10
Release date:2010-06-23
Last modified:2015-04-22
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure of nitrilotriacetate monooxygenase component B from Mycobacterium thermoresistibile.
Acta Crystallogr.,Sect.F, 67, 2011
3NXS
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CRYSTAL STRUCTURE OF LAO/AO TRANSPORT SYSTEM FROM MYCOBACTERIUM SMEGMATIS BOUND TO GDP
Descriptor:LAO/AO transport system ATPase, GUANOSINE-5'-DIPHOSPHATE, CHLORIDE ION
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2010-07-14
Release date:2010-07-28
Last modified:2015-06-03
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structures of Mycobacterial MeaB and MMAA-like GTPases
J.Struct.Funct.Genom., 16, 2015
3P0Z
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CRYSTAL STRUCTURE OF 2-C-METHYL-D-ERYTHRITOL 2,4-CYCLODIPHOSPHATE SYNTHASE FROM BURKHOLDERIA PSEUDOMALLEI WITH CYTIDINE AND FOL955, 4-(1H-IMIDAZOL)-1-YL)PHENOL
Descriptor:2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, CHLORIDE ION, ZINC ION, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2010-09-29
Release date:2010-10-20
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Leveraging structure determination with fragment screening for infectious disease drug targets: MECP synthase from Burkholderia pseudomallei.
J Struct Funct Genomics, 12, 2011
3P10
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CRYSTAL STRUCTURE OF 2-C-METHYL-D-ERYTHRITOL 2,4-CYCLODIPHOSPHATE SYNTHASE FROM BURKHOLDERIA PSEUDOMALLEI WITH CYTIDINE AND FOL694, 2-(THIOPHEN-2-YL)PHENYL METHANOL
Descriptor:2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, CHLORIDE ION, ZINC ION, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2010-09-29
Release date:2010-11-10
Last modified:2013-10-30
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Leveraging structure determination with fragment screening for infectious disease drug targets: MECP synthase from Burkholderia pseudomallei.
J Struct Funct Genomics, 12, 2011
3P3A
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CRYSTAL STRUCTURE OF A PUTATIVE THIOSULFATE SULFURTRANSFERASE FROM MYCOBACTERIUM THERMORESISTIBLE
Descriptor:Thiosulfate sulfurtransferase
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2010-10-04
Release date:2010-10-13
Last modified:2015-04-22
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Mycobacterium thermoresistibile as a source of thermostable orthologs of Mycobacterium tuberculosis proteins.
Protein Sci., 21, 2012
3PXU
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CRYSTAL STRUCTURE OF PHOSPHOPANTETHEINE ADENYLYLTRANSFERASE FROM BURKHOLDERIA PSEUDOMALLEI BOUND TO DEPHOSPHO-COENZYME A
Descriptor:Phosphopantetheine adenylyltransferase, DEPHOSPHO COENZYME A, GLYCEROL, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2010-12-10
Release date:2010-12-22
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structures of phosphopantetheine adenylyltransferase from Burkholderia pseudomallei.
Acta Crystallogr.,Sect.F, 67, 2011
3Q8H
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CRYSTAL STRUCTURE OF 2C-METHYL-D-ERYTHRITOL 2,4-CYCLODIPHOSPHATE SYNTHASE FROM BURKHOLDERIA PSEUDOMALLEI IN COMPLEX WITH CYTIDINE DERIVATIVE EBSI01028
Descriptor:2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, ZINC ION, 5'-deoxy-5'-[(imidazo[2,1-b][1,3]thiazol-5-ylcarbonyl)amino]cytidine, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2011-01-06
Release date:2011-01-19
Last modified:2013-12-11
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Cytidine derivatives as IspF inhibitors of Burkolderia pseudomallei.
Bioorg.Med.Chem.Lett., 23, 2013
3QH4
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CRYSTAL STRUCTURE OF ESTERASE LIPW FROM MYCOBACTERIUM MARINUM
Descriptor:Esterase LipW
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2011-01-25
Release date:2011-02-09
Last modified:2016-12-21
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural Basis for the Strict Substrate Selectivity of the Mycobacterial Hydrolase LipW.
Biochemistry, 95, 2016
3QHD
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CRYSTAL STRUCTURE OF 2-C-METHYL-D-ERYTHRITOL 2,4-CYCLODIPHOSPHATE SYNTHASE FROM BURKHOLDERIA PSEUDOMALLEI BOUND TO CYTIDINE, FOL795 AND FOL955
Descriptor:2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, ZINC ION, CHLORIDE ION, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2011-01-25
Release date:2011-02-09
Last modified:2013-10-30
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Leveraging structure determination with fragment screening for infectious disease drug targets: MECP synthase from Burkholderia pseudomallei.
J Struct Funct Genomics, 12, 2011
3QHX
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CRYSTAL STRUCTURE OF CYSTATHIONINE GAMMA-SYNTHASE METB (CGS) FROM MYCOBACTERIUM ULCERANS AGY99 BOUND TO HEPES
Descriptor:Cystathionine gamma-synthase MetB (Cgs), SULFATE ION, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2011-01-26
Release date:2011-03-02
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structure of the cystathionine [gamma]-synthase MetB from Mycobacterium ulcerans
Acta Crystallogr.,Sect.F, 67, 2011
3QI6
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CRYSTAL STRUCTURE OF CYSTATHIONINE GAMMA-SYNTHASE METB (CGS) FROM MYCOBACTERIUM ULCERANS AGY99
Descriptor:Cystathionine gamma-synthase MetB (Cgs), SULFATE ION, SODIUM ION, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2011-01-26
Release date:2011-03-02
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Structure of the cystathionine [gamma]-synthase MetB from Mycobacterium ulcerans
Acta Crystallogr.,Sect.F, 67, 2011
3TK1
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CRYSTAL STRUCTURE OF A MEAB AND RV1496 ORTHOLOG FROM MYCOBACTERIUM THERMORESISTIBLE BOUND TO GDP
Descriptor:Membrane ATPase/protein kinase, GUANOSINE-5'-DIPHOSPHATE, CHLORIDE ION
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2011-08-25
Release date:2011-10-05
Last modified:2015-06-03
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structures of Mycobacterial MeaB and MMAA-like GTPases.
J.Struct.Funct.Genom., 16, 2015
4E51
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CRYSTAL STRUCTURE OF A HISTIDYL-TRNA SYNTHETASE HISRS FROM BURKHOLDERIA THAILANDENSIS BOUND TO HISTIDINE
Descriptor:Histidine--tRNA ligase, HISTIDINE
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2012-03-13
Release date:2012-03-28
Last modified:2017-03-29
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Ligand co-crystallization of aminoacyl-tRNA synthetases from infectious disease organisms.
Sci Rep, 7, 2017
5IS2
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CRYSTAL STRUCTURE OF MYCOBACTERIUM AVIUM SERB2 AT PH 6.6
Descriptor:Phosphoserine phosphatase, MAGNESIUM ION
Authors:Shree, S., Ramachandran, R.
Deposit date:2016-03-15
Release date:2016-04-27
Method:X-RAY DIFFRACTION (1.881 Å)
Cite:Crystal Structure of Mycobacterium avium SerB2 (MAV_3907) at pH 6.6
To be published
5IT0
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CRYSTAL STRUCTURE OF MYCOBACTERIUM AVIUM SERB2 MUTANT D343N/D347N
Descriptor:Phosphoserine phosphatase, MAGNESIUM ION
Authors:Shree, S., Ramachandran, R.
Deposit date:2016-03-16
Release date:2016-04-27
Method:X-RAY DIFFRACTION (1.968 Å)
Cite:Crystal Structure of Mycobacterium avium SerB2 (MAV_3907) active site mutant D343N/D347N
To be published
5IT4
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CRYSTAL STRUCTURE OF MYCOBACTERIUM AVIUM SERB2 MUTANT D343N
Descriptor:Phosphoserine phosphatase, MAGNESIUM ION
Authors:Shree, S., Ramachandran, R.
Deposit date:2016-03-16
Release date:2016-04-27
Method:X-RAY DIFFRACTION (2.102 Å)
Cite:Crystal Structure of Mycobacterium avium SerB2 mutant D343N (MAV_3907) at pH 6.6
To be published