Author results

6DCW
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CRYSTAL STRUCTURE OF HUMAN ANTI-TAU ANTIBODY CBTAU-27.1 FAB IN COMPLEX WITH A HUMAN TAU PEPTIDE
Descriptor:Light chain of CBTAU27.1 Fab, Heavy chain of CBTAU27.1 Fab, tau peptide
Authors:Zhu, X., Zhang, H., Wilson, I.A.
Deposit date:2018-05-08
Release date:2018-06-06
Last modified:2018-06-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:A common antigenic motif recognized by naturally occurring human VH5-51/VL4-1 anti-tau antibodies with distinct functionalities.
Acta Neuropathol Commun, 6, 2018
3PYY
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DISCOVERY AND CHARACTERIZATION OF A CELL-PERMEABLE, SMALL-MOLECULE C-ABL KINASE ACTIVATOR THAT BINDS TO THE MYRISTOYL BINDING SITE
Descriptor:V-abl Abelson murine leukemia viral oncogene homolog 1 isoform b variant, SULFATE ION, 4-(4-METHYL-PIPERAZIN-1-YLMETHYL)-N-[4-METHYL-3-(4-PYRIDIN-3-YL-PYRIMIDIN-2-YLAMINO)-PHENYL]-BENZAMIDE, ...
Authors:Yang, J., Campobasso, N., Biju, M.P., Fisher, K., Pan, X.Q., Cottom, J., Galbraith, S., Ho, T., Zhang, H., Hong, X., Ward, P., Hofmann, G., Siegfried, B.
Deposit date:2010-12-13
Release date:2011-03-09
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Discovery and Characterization of a Cell-Permeable, Small-Molecule c-Abl Kinase Activator that Binds to the Myristoyl Binding Site.
Chem.Biol., 18, 2011
4E5K
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THERMOSTABLE PHOSPHITE DEHYDROGENASE IN COMPLEX WITH NAD AND SULFITE
Descriptor:Phosphite dehydrogenase (thermostable variant), NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SULFITE ION
Authors:Zou, Y., Zhang, H., Nair, S.K.
Deposit date:2012-03-14
Release date:2012-05-30
Last modified:2012-06-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal structures of phosphite dehydrogenase provide insights into nicotinamide cofactor regeneration.
Biochemistry, 51, 2012
4E5M
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THERMOSTABLE PHOSPHITE DEHYDROGENASE E175A/A176R IN COMPLEX WITH NADP
Descriptor:Thermostable phosphite dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Zou, Y., Zhang, H., Nair, S.K.
Deposit date:2012-03-14
Release date:2012-05-30
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal structures of phosphite dehydrogenase provide insights into nicotinamide cofactor regeneration.
Biochemistry, 51, 2012
4E5N
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THERMOSTABLE PHOSPHITE DEHYDROGENASE IN COMPLEX WITH NAD
Descriptor:Thermostable phosphite dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Zou, Y., Zhang, H., Nair, S.K.
Deposit date:2012-03-14
Release date:2012-05-30
Last modified:2012-06-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structures of phosphite dehydrogenase provide insights into nicotinamide cofactor regeneration.
Biochemistry, 51, 2012
4E5P
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THERMOSTABLE PHOSPHITE DEHYDROGENASE A176R VARIANT IN COMPLEX WITH NAD
Descriptor:Thermostable phosphite dehydrogenase A176R variant, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Zou, Y., Zhang, H., Nair, S.K.
Deposit date:2012-03-14
Release date:2012-05-30
Last modified:2012-06-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structures of phosphite dehydrogenase provide insights into nicotinamide cofactor regeneration.
Biochemistry, 51, 2012
4EBF
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SEMET THERMOSTABLE PHOSPHITE DEHYDROGENASE GLU175-ALA MUTANT
Descriptor:Thermostable phosphite dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Zou, Y., Zhang, H., Nair, S.K.
Deposit date:2012-03-23
Release date:2012-05-30
Last modified:2012-06-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structures of phosphite dehydrogenase provide insights into nicotinamide cofactor regeneration.
Biochemistry, 51, 2012
4XWT
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CRYSTAL STRUCTURE OF RNASE J COMPLEXED WITH UMP
Descriptor:DR2417, ZINC ION, MANGANESE (II) ION, ...
Authors:Lu, M., Zhang, H., Xu, Q., Hua, Y., Zhao, Y.
Deposit date:2015-01-29
Release date:2015-12-16
Method:X-RAY DIFFRACTION (2.003 Å)
Cite:Structural insights into catalysis and dimerization enhanced exonuclease activity of RNase J
Nucleic Acids Res., 43, 2015
4XWW
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CRYSTAL STRUCTURE OF RNASE J COMPLEXED WITH RNA
Descriptor:DR2417, RNA (5'-D(UP*UP*UP*UP*UP*UP*U)-3'), ZINC ION, ...
Authors:Lu, M., Zhang, H., Xu, Q., Hua, Y., Zhao, Y.
Deposit date:2015-01-29
Release date:2015-12-16
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural insights into catalysis and dimerization enhanced exonuclease activity of RNase J
Nucleic Acids Res., 43, 2015
5HEK
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CRYSTAL STRUCTURE OF M1.HPYAVI
Descriptor:Adenine specific DNA methyltransferase (DpnA)
Authors:Ma, B., Zhang, H., Liu, W.
Deposit date:2016-01-06
Release date:2016-11-16
Last modified:2016-11-30
Method:X-RAY DIFFRACTION (3 Å)
Cite:Biochemical and structural characterization of a DNA N6-adenine methyltransferase from Helicobacter pylori
Oncotarget, 7, 2016
5HFJ
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CRYSTAL STRUCTURE OF M1.HPYAVI-SAM COMPLEX
Descriptor:Adenine specific DNA methyltransferase (DpnA), S-ADENOSYLMETHIONINE
Authors:Ma, B., Liu, W., Zhang, H.
Deposit date:2016-01-07
Release date:2016-11-16
Last modified:2016-11-30
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Biochemical and structural characterization of a DNA N6-adenine methyltransferase from Helicobacter pylori
Oncotarget, 7, 2016
5V7R
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CYRSTAL STRUCTURE OF ANTI-TAU ANTIBODY CBTAU-7.1 FAB
Descriptor:CBTAU-7.1 Fab light chain, CBTAU-7.1 Fab heavy chain
Authors:Zhu, X., Zhang, H., Wilson, I.A.
Deposit date:2017-03-20
Release date:2017-04-12
Last modified:2017-04-26
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Immunological memory to hyperphosphorylated tau in asymptomatic individuals.
Acta Neuropathol., 133, 2017
5V7U
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CYRSTAL STRUCTURE OF ANTI-TAU ANTIBODY CBTAU-22.1 FAB
Descriptor:CBTAU-22.1 Fab light chain, CBTAU-22.1 Fab heavy chain, SULFATE ION
Authors:Zhu, X., Zhang, H., Wilson, I.A.
Deposit date:2017-03-20
Release date:2017-04-12
Last modified:2017-04-26
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:Immunological memory to hyperphosphorylated tau in asymptomatic individuals.
Acta Neuropathol., 133, 2017
1IJL
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CRYSTAL STRUCTURE OF ACIDIC PHOSPHOLIPASE A2 FROM DEINAGKISTRODON ACUTUS
Descriptor:PHOSPHOLIPASE A2, ZINC ION, CALCIUM ION
Authors:Gu, L., Zhang, H., Song, S., Zhou, Y., Lin, Z.
Deposit date:2001-04-27
Release date:2001-12-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of an acidic phospholipase A2 from the venom of Deinagkistrodon acutus.
Acta Crystallogr.,Sect.D, 58, 2002
1AE2
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MUTANT L32R OF GENE V PROTEIN (SINGLE-STRANDED DNA BINDING PROTEIN)
Descriptor:GENE V PROTEIN
Authors:Su, S., Gao, Y.-G., Zhang, H., Terwilliger, T.C., Wang, A.H.-J.
Deposit date:1997-03-04
Release date:1997-09-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Analyses of the stability and function of three surface mutants (R82C, K69H, and L32R) of the gene V protein from Ff phage by X-ray crystallography.
Protein Sci., 6, 1997
1AE3
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MUTANT R82C OF GENE V PROTEIN (SINGLE-STRANDED DNA BINDING PROTEIN)
Descriptor:GENE V PROTEIN
Authors:Su, S., Gao, Y.-G., Zhang, H., Terwilliger, T.C., Wang, A.H.-J.
Deposit date:1997-03-04
Release date:1997-09-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Analyses of the stability and function of three surface mutants (R82C, K69H, and L32R) of the gene V protein from Ff phage by X-ray crystallography.
Protein Sci., 6, 1997
1EET
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HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH THE INHIBITOR MSC204
Descriptor:HIV-1 REVERSE TRANSCRIPTASE, 1-(5-BROMO-PYRIDIN-2-YL)-3-[2-(6-FLUORO-2-HYDROXY-3-PROPIONYL-PHENYL)-CYCLOPROPYL]-UREA
Authors:Hogberg, M., Sahlberg, C., Engelhardt, P., Noreen, R., Kangasmetsa, J., Johansson, N.G., Oberg, B., Vrang, L., Zhang, H., Sahlberg, B.L., Unge, T., Lovgren, S., Fridborg, K., Backbro, K.
Deposit date:2000-02-03
Release date:2001-02-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.73 Å)
Cite:Urea-PETT compounds as a new class of HIV-1 reverse transcriptase inhibitors. 3. Synthesis and further structure-activity relationship studies of PETT analogues.
J.Med.Chem., 42, 1999
1FWK
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CRYSTAL STRUCTURE OF HOMOSERINE KINASE COMPLEXED WITH ADP
Descriptor:HOMOSERINE KINASE, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
Authors:Zhou, T., Daugherty, M., Grishin, N.V., Osterman, A.L., Zhang, H.
Deposit date:2000-09-22
Release date:2000-12-20
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure and mechanism of homoserine kinase: prototype for the GHMP kinase superfamily.
Structure Fold.Des., 8, 2000
1FWL
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CRYSTAL STRUCTURE OF HOMOSERINE KINASE
Descriptor:HOMOSERINE KINASE
Authors:Zhou, T., Daugherty, M., Grishin, N.V., Osterman, A.L., Zhang, H.
Deposit date:2000-09-22
Release date:2000-12-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structure and mechanism of homoserine kinase: prototype for the GHMP kinase superfamily.
Structure Fold.Des., 8, 2000
1G5J
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COMPLEX OF BCL-XL WITH PEPTIDE FROM BAD
Descriptor:APOPTOSIS REGULATOR BCL-X, BAD PROTEIN
Authors:Petros, A.M., Nettesheim, D.G., Wang, Y., Olejniczak, E.T., Meadows, R.P., Mack, J., Swift, K., Matayoshi, E.D., Zhang, H., Thompson, C.B., Fesik, S.W.
Deposit date:2000-11-01
Release date:2001-02-07
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Rationale for Bcl-xL/Bad peptide complex formation from structure, mutagenesis, and biophysical studies.
Protein Sci., 9, 2000
1GKH
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MUTANT K69H OF GENE V PROTEIN (SINGLE-STRANDED DNA BINDING PROTEIN)
Descriptor:GENE V PROTEIN
Authors:Su, S., Gao, Y.-G., Zhang, H., Terwilliger, T.C., Wang, A.H.-J.
Deposit date:1997-03-04
Release date:1997-09-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Analyses of the stability and function of three surface mutants (R82C, K69H, and L32R) of the gene V protein from Ff phage by X-ray crystallography.
Protein Sci., 6, 1997
1GQ2
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MALIC ENZYME FROM PIGEON LIVER
Descriptor:MALIC ENZYME, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, OXALATE ION, ...
Authors:Yang, Z., Zhang, H., Liang, T.
Deposit date:2001-11-19
Release date:2002-05-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Studies of the Pigeon Cytosolic Nadp+ -Dependent Malic Enzyme
Protein Sci., 11, 2002
1GVP
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GENE V PROTEIN (SINGLE-STRANDED DNA BINDING PROTEIN)
Descriptor:GENE V PROTEIN
Authors:Su, S., Gao, Y.-G., Zhang, H., Terwilliger, T.C., Wang, A.H.-J.
Deposit date:1997-02-26
Release date:1997-09-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Analyses of the stability and function of three surface mutants (R82C, K69H, and L32R) of the gene V protein from Ff phage by X-ray crystallography.
Protein Sci., 6, 1997
1IM8
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CRYSTAL STRUCTURE OF YECO FROM HAEMOPHILUS INFLUENZAE (HI0319), A METHYLTRANSFERASE WITH A BOUND S-ADENOSYLHOMOCYSTEINE
Descriptor:YecO, CHLORIDE ION, S-ADENOSYL-L-HOMOSELENOCYSTEINE
Authors:Lim, K., Zhang, H., Tempczyk, A., Bonander, N., Toedt, J., Howard, A., Eisenstein, E., Herzberg, O., Structure 2 Function Project (S2F)
Deposit date:2001-05-10
Release date:2001-11-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of YecO from Haemophilus influenzae (HI0319) reveals a methyltransferase fold and a bound S-adenosylhomocysteine.
Proteins, 45, 2001
1J85
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STRUCTURE OF YIBK FROM HAEMOPHILUS INFLUENZAE (HI0766), A TRUNCATED SEQUENCE HOMOLOG OF TRNA (GUANOSINE-2'-O-) METHYLTRANSFERASE (SPOU)
Descriptor:YibK
Authors:Lim, K., Zhang, H., Toedt, J., Tempcyzk, A., Krajewski, W., Howard, A., Eisenstein, E., Herzberg, O., Structure 2 Function Project (S2F)
Deposit date:2001-05-20
Release date:2003-02-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of the YibK methyltransferase from Haemophilus influenzae (HI0766): A cofactor bound at a site formed by a knot
Proteins, 51, 2003