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5K0U
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CRYOEM STRUCTURE OF THE FULL VIRION OF A HUMAN RHINOVIRUS C
分子名称:Capsid protein VP1, Capsid protein VP3, Capsid protein VP2, ...
著者Liu, Y., Hill, M.G., Klose, T., Chen, Z., Watters, K.E., Jiang, W., Palmenberg, A.C., Rossmann, M.G.
登録日2016-05-17
公開日2016-07-13
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (2.79 Å)
主引用文献Atomic structure of a rhinovirus C, a virus species linked to severe childhood asthma.
Proc.Natl.Acad.Sci.USA, 113, 2016
5JZC
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HELICAL FILAMENT
分子名称:DNA repair protein RAD51 homolog 1
著者Short, J., Liu, Y.
登録日2016-05-16
公開日2016-09-21
最終更新日2018-10-17
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献High-resolution structure of the presynaptic RAD51 filament on single-stranded DNA by electron cryo-microscopy.
Nucleic Acids Res., 44, 2016
5JZG
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CRYOEM STRUCTURE OF THE NATIVE EMPTY PARTICLE OF A HUMAN RHINOVIRUS C
分子名称:Capsid protein VP1, Capsid protein VP3, Capsid protein VP0
著者Liu, Y., Hill, M.G., Klose, T., Chen, Z., Watters, K.E., Jiang, W., Palmenberg, A.C., Rossmann, M.G.
登録日2016-05-16
公開日2016-07-13
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (3.16 Å)
主引用文献Atomic structure of a rhinovirus C, a virus species linked to severe childhood asthma.
Proc.Natl.Acad.Sci.USA, 113, 2016
5JNR
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CRYSTAL STRUCTURE OF HUMAN LOW MOLECULAR WEIGHT PROTEIN TYROSINE PHOSPHATASE (LMPTP) TYPE A
分子名称:Low molecular weight phosphotyrosine protein phosphatase
著者Stanford, S.M., Aleshin, A.E., Liddington, R.C., Bankston, L., Cadwell, G., Bottini, N.
登録日2016-04-30
公開日2017-03-29
最終更新日2017-09-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Diabetes reversal by inhibition of the low-molecular-weight tyrosine phosphatase.
Nat. Chem. Biol., 13, 2017
5JNS
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CRYSTAL STRUCTURE OF HUMAN LOW MOLECULAR WEIGHT PROTEIN TYROSINE PHOSPHATASE (LMPTP) TYPE A COMPLEXED WITH PHOSPHATE
分子名称:Low molecular weight phosphotyrosine protein phosphatase, PHOSPHATE ION, DIMETHYL SULFOXIDE
著者Stanford, S.M., Aleshin, A.E., Liddington, R.C., Bankston, L., Cadwell, G., Bottini, N.
登録日2016-04-30
公開日2017-03-29
最終更新日2017-09-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Diabetes reversal by inhibition of the low-molecular-weight tyrosine phosphatase.
Nat. Chem. Biol., 13, 2017
5JNT
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CRYSTAL STRUCTURE OF HUMAN LOW MOLECULAR WEIGHT PROTEIN TYROSINE PHOSPHATASE (LMPTP) TYPE A COMPLEXED WITH MES
分子名称:Low molecular weight phosphotyrosine protein phosphatase, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DIMETHYL SULFOXIDE, ...
著者Stanford, S.M., Aleshin, A.E., Liddington, R.C., Bankston, L., Cadwell, G., Bottini, N.
登録日2016-04-30
公開日2017-03-29
最終更新日2017-09-20
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Diabetes reversal by inhibition of the low-molecular-weight tyrosine phosphatase.
Nat. Chem. Biol., 13, 2017
5JNU
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CRYSTAL STRUCTURE OF MOUSE LOW-MOLECULAR WEIGHT PROTEIN TYROSINE PHOSPHATASE TYPE A (LMPTP-A) COMPLEXED WITH PHOSPHATE
分子名称:Low molecular weight phosphotyrosine protein phosphatase, PHOSPHATE ION
著者Stanford, S.M., Aleshin, A.E., Liddington, R.C., Bankston, L., Cadwell, G., Bottini, N.
登録日2016-04-30
公開日2017-03-29
最終更新日2017-09-20
実験手法X-RAY DIFFRACTION (2.535 Å)
主引用文献Diabetes reversal by inhibition of the low-molecular-weight tyrosine phosphatase.
Nat. Chem. Biol., 13, 2017
5JNV
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CRYSTAL STRUCTURE OF BOVINE LOW MOLECULAR WEIGHT PROTEIN TYROSINE PHOSPHATASE (LMPTP) MUTANT (W49Y N50E) COMPLEXED WITH HEPES
分子名称:Low molecular weight phosphotyrosine protein phosphatase, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DIMETHYL SULFOXIDE
著者Stanford, S.M., Aleshin, A.E., Liddington, R.C., Bankston, L., Cadwell, G., Bottini, N.
登録日2016-04-30
公開日2017-03-29
最終更新日2017-09-20
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Diabetes reversal by inhibition of the low-molecular-weight tyrosine phosphatase.
Nat. Chem. Biol., 13, 2017
5JNW
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CRYSTAL STRUCTURE OF BOVINE LOW MOLECULAR WEIGHT PROTEIN TYROSINE PHOSPHATASE (LMPTP) MUTANT (W49Y N50E) COMPLEXED WITH VANADATE AND UNCOMPETITIVE INHIBITOR
分子名称:Low molecular weight phosphotyrosine protein phosphatase, VANADATE ION, 2-(4-{[3-(piperidin-1-yl)propyl]amino}quinolin-2-yl)benzonitrile
著者Stanford, S.M., Aleshin, A.E., Liddington, R.C., Bankston, L., Cadwell, G., Bottini, N.
登録日2016-04-30
公開日2017-03-29
最終更新日2017-09-20
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Diabetes reversal by inhibition of the low-molecular-weight tyrosine phosphatase.
Nat. Chem. Biol., 13, 2017
5J5N
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CRYSTAL STRUCTURE OF THE R39W MUTANT OF POPULUS TRICHOCARPA GLUTATHIONE TRANSFERASE PTGSTU30 IN COMPLEX WITH GLUTATHIONE
分子名称:Glutathione transferase family protein, GLUTATHIONE
著者Yang, Q., Gu, J., Yang, M., Zeng, Q.
登録日2016-04-03
公開日2017-04-12
実験手法X-RAY DIFFRACTION (2.629 Å)
主引用文献Functional and Structural Profiles of GST Gene Family from Three Populus Species Revealed the Sequence-function Decoupling of Orthologous Genes
To Be Published
5J4U
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CRYSTAL STRUCTURE OF A GLUTATHIONE S-TRANSFERASE PTGSTU30 FROM POPULUS TRICHOCARPA IN COMPLEX WITH GSH
分子名称:Glutathione transferase family protein, GLUTATHIONE
著者Yang, Q., Gu, J., Yang, M., Zeng, Q.
登録日2016-04-01
公開日2017-04-12
実験手法X-RAY DIFFRACTION (1.249 Å)
主引用文献Functional and Structural Profiles of GST Gene Family from Three Populus Species Revealed the Sequence-function Decoupling of Orthologous Genes
To Be Published
5J41
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GLUTATHIONE S-TRANSFERASE BOUND WITH HYDROLYZED PIPERLONGUMINE
分子名称:Glutathione S-transferase P, 3-(3,4,5-trimethoxyphenyl)propanoic acid, GLUTATHIONE, ...
著者Harshbarger, W., Gondi, S., Ficarro, S., Hunter, J., Udayakumar, D., Gurbani, D., Marto, J., Westover, K.
登録日2016-03-31
公開日2016-11-30
最終更新日2017-01-18
実験手法X-RAY DIFFRACTION (1.190354 Å)
主引用文献Structural and Biochemical Analyses Reveal the Mechanism of Glutathione S-Transferase Pi 1 Inhibition by the Anti-cancer Compound Piperlongumine.
J. Biol. Chem., 292, 2017
5IZ0
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RORGAMMA IN COMPLEX WITH AGONIST BIO592 AND COACTIVATOR EBI96
分子名称:Nuclear receptor ROR-gamma, GLU-PHE-PRO-TYR-LEU-LEU-SER-LEU-LEU-GLY-GLU-VAL-SER-PRO-GLN, N-(4-ethyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-7-yl)-3,4-dimethyl-N-(2,2,2-trifluoroethyl)benzene-1-sulfonamide, ...
著者Marcotte, D.J.
登録日2016-03-24
公開日2016-06-15
実験手法X-RAY DIFFRACTION (2.635 Å)
主引用文献Structural determinant for inducing RORgamma specific inverse agonism triggered by a synthetic benzoxazinone ligand.
Bmc Struct.Biol., 16, 2016
5IXK
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RORGAMMA IN COMPLEX WITH INVERSE AGONIST BIO399.
分子名称:Nuclear receptor ROR-gamma, N-(5-ethyl-3,3-dimethyl-4-oxo-2,3,4,5-tetrahydro-1,5-benzoxazepin-8-yl)-3,4-dimethyl-N-(2,2,2-trifluoroethyl)benzene-1-sulfonamide
著者Marcotte, D.J.
登録日2016-03-23
公開日2016-06-15
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structural determinant for inducing RORgamma specific inverse agonism triggered by a synthetic benzoxazinone ligand.
Bmc Struct.Biol., 16, 2016
5IXS
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LACTATE DEHYDROGENASE IN COMPLEX WITH HYDROXYLACTAM INHIBITOR COMPOUND 9: (6R)-3-[(2-CHLOROPHENYL)SULFANYL]-4-HYDROXY-6-(3-HYDROXYPHENYL)-6-(THIOPHEN-3-YL)-5,6-DIHYDROPYRIDIN-2(1H)-ONE
分子名称:L-lactate dehydrogenase A chain, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 1,4,5,6-TETRAHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ...
著者Ultsch, M., Eigenbrot, C.
登録日2016-03-23
公開日2016-09-14
最終更新日2016-11-09
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Cell Active Hydroxylactam Inhibitors of Human Lactate Dehydrogenase with Oral Bioavailability in Mice.
Acs Med.Chem.Lett., 7, 2016
5IXY
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LACTATE DEHYDROGENASE IN COMPLEX WITH HYDROXYLACTAM INHIBITOR COMPOUND 31: (2~{S})-5-(2-CHLOROPHENYL)SULFANYL-2-(4-MORPHOLIN-4-YLPHENYL)-4-OXIDANYL-2-THIOPHEN-3-YL-1,3-DIHYDROPYRIDIN-6-ONE
分子名称:L-lactate dehydrogenase A chain, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SULFATE ION, ...
著者Chen, Z., Eigenbrot, C.
登録日2016-03-23
公開日2016-09-14
最終更新日2016-11-09
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Cell Active Hydroxylactam Inhibitors of Human Lactate Dehydrogenase with Oral Bioavailability in Mice.
Acs Med.Chem.Lett., 7, 2016
5G06
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CRYO-EM STRUCTURE OF YEAST CYTOPLASMIC EXOSOME
分子名称:EXOSOME COMPLEX COMPONENT RRP45, EXOSOME COMPLEX COMPONENT SKI6, EXOSOME COMPLEX COMPONENT RRP43, ...
著者Liu, J.J., Niu, C.Y., Wu, Y., Tan, D., Wang, Y., Ye, M.D., Liu, Y., Zhao, W.W., Zhou, K., Liu, Q.S., Dai, J.B., Yang, X.R., Dong, M.Q., Huang, N., Wang, H.W.
登録日2016-03-17
公開日2016-06-15
最終更新日2017-08-02
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Cryoem Structure of Yeast Cytoplasmic Exosome Complex.
Cell Res., 26, 2016
5ISY
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CRYSTAL STRUCTURE OF NUDIX FAMILY PROTEIN WITH NAD
分子名称:NADH pyrophosphatase, ZINC ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Zhang, D., Guan, Z., Zou, T., Yin, P.
登録日2016-03-15
公開日2016-09-14
実験手法X-RAY DIFFRACTION (2.354 Å)
主引用文献Structural basis of prokaryotic NAD-RNA decapping by NudC
Cell Res., 26, 2016
5IN1
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CRYSTAL STRUCTURE OF THE MRG701 CHROMODOMAIN
分子名称:MRG701, SULFATE ION, 1,2-ETHANEDIOL
著者Huang, Y., Liu, Y.
登録日2016-03-07
公開日2017-03-01
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structural studies on MRG701 chromodomain reveal a novel dimerization interface of MRG proteins in green plants
Protein Cell, 7, 2016
5IM4
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CRYSTAL STRUCTURE OF DESIGNED TWO-COMPONENT SELF-ASSEMBLING ICOSAHEDRAL CAGE I52-32
分子名称:6,7-dimethyl-8-ribityllumazine synthase, Phosphotransferase system, mannose/fructose-specific component IIA
著者Liu, Y.A., Cascio, D., Sawaya, M.R., Bale, J.B., Collazo, M.J., Thomas, C., Sheffler, W., King, N.P., Baker, D., Yeates, T.O.
登録日2016-03-05
公開日2016-07-27
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Accurate design of megadalton-scale two-component icosahedral protein complexes.
Science, 353, 2016
5IM5
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CRYSTAL STRUCTURE OF DESIGNED TWO-COMPONENT SELF-ASSEMBLING ICOSAHEDRAL CAGE I53-40
分子名称:Designed Riboflavin synthase, Designed Keto-hydroxyglutarate-aldolase/keto-deoxy-phosphogluconate aldolase
著者Liu, Y.A., Cascio, D., Sawaya, M.R., Bale, J.B., Collazo, M.J., Thomas, C., Sheffler, W., King, N.P., Baker, D., Yeates, T.O.
登録日2016-03-05
公開日2016-07-27
最終更新日2016-08-10
実験手法X-RAY DIFFRACTION (3.699 Å)
主引用文献Accurate design of megadalton-scale two-component icosahedral protein complexes.
Science, 353, 2016
5IM6
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CRYSTAL STRUCTURE OF DESIGNED TWO-COMPONENT SELF-ASSEMBLING ICOSAHEDRAL CAGE I32-28
分子名称:Designed self-assembling icosahedral cage I32-28 trimeric subunit, Designed self-assembling icosahedral cage I32-28 dimeric subunit
著者Liu, Y.A., Cascio, D., Sawaya, M.R., Bale, J.B., Collazo, M.J., Thomas, C., Sheffler, W., King, N.P., Baker, D., Yeates, T.O.
登録日2016-03-05
公開日2016-07-27
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (5.588 Å)
主引用文献Accurate design of megadalton-scale two-component icosahedral protein complexes.
Science, 353, 2016
5I9D
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CRYSTAL STRUCTURE OF DESIGNED PENTATRICOPEPTIDE REPEAT PROTEIN DPPR-U8A2 IN COMPLEX WITH ITS TARGET RNA U8A2
分子名称:pentatricopeptide repeat protein dPPR-U8A2, RNA (5'-R(*GP*GP*GP*G*UP*UP*UP*UP*AP*AP*UP*UP*UP*UP*CP*CP*CP*C)-3')
著者Shen, C., Zhang, D., Guan, Z., Zou, T., Yin, P.
登録日2016-02-20
公開日2016-04-27
実験手法X-RAY DIFFRACTION (2.596 Å)
主引用文献Structure of RNA binding protein with target RNA
Nat Commun, 2016
5I9F
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CRYSTAL STRUCTURE OF DESIGNED PENTATRICOPEPTIDE REPEAT PROTEIN DPPR-U10 IN COMPLEX WITH ITS TARGET RNA U10
分子名称:pentatricopeptide repeat protein dPPR-U10, RNA (5'-R(*GP*GP*GP*GP*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*CP*CP*CP*C)-3')
著者Shen, C., Zhang, D., Guan, Z., Zou, T., Yin, Y.
登録日2016-02-20
公開日2016-04-27
実験手法X-RAY DIFFRACTION (2.194 Å)
主引用文献Structure of RNA binding protein with target RNA
Nat Commun, 2016
5I9G
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CRYSTAL STRUCTURE OF DESIGNED PENTATRICOPEPTIDE REPEAT PROTEIN DPPR-U8C2 IN COMPLEX WITH ITS TARGET RNA U8C2
分子名称:pentatricopeptide repeat protein dPPR-U8C2, RNA (5'-R(*GP*GP*G*GP*UP*UP*UP*UP*CP*CP*UP*UP*UP*UP*CP*CP*CP*C)-3')
著者Shen, C., Zhang, D., Guan, Z., Zou, T., Yin, P.
登録日2016-02-20
公開日2016-04-27
最終更新日2017-10-04
実験手法X-RAY DIFFRACTION (2.288 Å)
主引用文献Structure of RNA binding protein with target RNA
Nat Commun, 2016