Author results

1WNC
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CRYSTAL STRUCTURE OF THE SARS-COV SPIKE PROTEIN FUSION CORE
分子名称:E2 glycoprotein
著者Xu, Y., Lou, Z., Liu, Y., Pang, H., Tien, P., Gao, G.F., Rao, Z.
登録日2004-07-29
公開日2004-09-07
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of severe acute respiratory syndrome coronavirus spike protein fusion core
J.Biol.Chem., 279, 2004
1WP7
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CRYSTAL STRUCTURE OF NIPAH VIRUS FUSION CORE
分子名称:fusion protein
著者Xu, Y., Liu, Y., Lou, Z., Su, N., Bai, Z., Gao, G.F., Rao, Z.
登録日2004-08-31
公開日2005-11-15
最終更新日2017-08-16
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of Nipah Virus fusion core
To be Published
1YO5
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ANALYSIS OF THE 2.0A CRYSTAL STRUCTURE OF THE PROTEIN-DNA COMPLEX OF HUMAN PDEF ETS DOMAIN BOUND TO THE PROSTATE SPECIFIC ANTIGEN REGULATORY SITE
分子名称:Enhancer site of Prostate Specific Antigen Promoter Region, SAM pointed domain containing ets transcription factor
著者Wang, Y., Feng, L., Said, M., Balderman, S., Fayazi, Z., Liu, Y., Ghosh, D., Gulick, A.M.
登録日2005-01-26
公開日2005-05-17
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Analysis of the 2.0 A Crystal Structure of the Protein-DNA Complex of the Human PDEF Ets Domain Bound to the Prostate Specific Antigen Regulatory Site
Biochemistry, 44, 2005
1ZKL
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MULTIPLE DETERMINANTS FOR INHIBITOR SELECTIVITY OF CYCLIC NUCLEOTIDE PHOSPHODIESTERASES
分子名称:High-affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A, ZINC ION, MAGNESIUM ION, ...
著者Wang, H., Liu, Y., Chen, Y., Robinson, H., Ke, H.
登録日2005-05-03
公開日2005-07-05
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.67 Å)
主引用文献Multiple elements jointly determine inhibitor selectivity of cyclic nucleotide phosphodiesterases 4 and 7
J.Biol.Chem., 280, 2005
2OTP
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CRYSTAL STRUCTURE OF IMMUNOGLOBULIN-LIKE TRANSCRIPT 1 (ILT1/LIR7/LILRA2)
分子名称:Leukocyte immunoglobulin-like receptor subfamily A member 2
著者Gao, F., Peng, H., Chen, Y., Liu, Y., Gao, G.F.
登録日2007-02-08
公開日2008-02-19
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal Structure of 3D Domain Swapped Dimer of Immunoglobulin-Like Transcript 1 (ILT1/LIR7/LILRA2), Molecular Insight into Group 1 Activating Receptor Forming Unique MW Interaction Pattern
To be Published
2Q3A
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CRYSTAL STRUCTURE OF RHESUS MACAQUE CD8 ALPHA-ALPHA HOMODIMER
分子名称:CD8
著者Peng, H., Chen, Y., Zong, L., Gao, F., Liu, Y., Gao, G.F.
登録日2007-05-30
公開日2008-06-17
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal Structure of Rhesus Macaque CD8 Homodimer Sheds the Lights on the Molecular Basis of Rhesus Macaque MHC class I with CD8 Complex
To be Published
2VGP
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CRYSTAL STRUCTURE OF AURORA B KINASE IN COMPLEX WITH A AMINOTHIAZOLE INHIBITOR
分子名称:SERINE/THREONINE-PROTEIN KINASE 12-A, INNER CENTROMERE PROTEIN A, 4-[(5-bromo-1,3-thiazol-2-yl)amino]-N-methylbenzamide
著者Andersen, C.B., Wan, Y., Chang, J.W., Lee, C., Liu, Y., Sessa, F., Villa, F., Nallan, L., Musacchio, A., Gray, N.S.
登録日2007-11-15
公開日2008-02-26
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Discovery of Selective Aminothiazole Aurora Kinase Inhibitors
Acs Chem.Biol., 3, 2008
2XCF
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CRYSTAL STRUCTURE OF HCV NS3 PROTEASE WITH A BORONATE INHIBITOR
分子名称:NS3 PROTEASE, NS4A, ZINC ION, ...
著者Li, X., Zhang, Y.-K., Liu, Y., Ding, C.Z., Li, Q., Zhou, Y., Plattner, J.J., Baker, S.J., Qian, X., Fan, D., Liao, L., Ni, Z.-J., White, G.V., Mordaunt, J.E., Lazarides, L.X., Slater, M.J., Jarvest, R.L., Thommes, P., Ellis, M., Edge, C.M., Hubbard, J.A., Nassau, P., McDowell, B., Skarzynski, T.J., Rowland, P., Somers, D.O., Kazmierski, W.M., Grimes, R.M., Wright, L.L., Smith, G.K., Zou, W., Wright, J., Pennicott, L.E.
登録日2010-04-22
公開日2010-06-02
最終更新日2019-02-06
実験手法X-RAY DIFFRACTION (2.48 Å)
主引用文献Synthesis and Evaluation of Novel Alpha-Amino Cyclic Boronates as Inhibitors of Hcv Ns3 Protease.
Bioorg.Med.Chem.Lett., 20, 2010
2XCN
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CRYSTAL STRUCTURE OF HCV NS3 PROTEASE WITH A BORONATE INHIBITOR
分子名称:NS3 PROTEASE, NS4A, N-[(CYCLOPENTYLOXY)CARBONYL]-3-METHYL-L-VALYL-(4R)-N-{(1R)-3-HYDROXY-1-[HYDROXY(OXIDO)BORANYL]PROPYL}-4-(ISOQUINOLIN-1-YLOXY)-L-PROLINAMIDE, ...
著者Li, X., Zhang, Y.-K., Liu, Y., Ding, C.Z., Li, Q., Zhou, Y., Plattner, J.J., Baker, S.J., Qian, X., Fan, D., Liao, L., Ni, Z.-J., White, G.V., Mordaunt, J.E., Lazarides, L.X., Slater, M.J., Jarvest, R.L., Thommes, P., Ellis, M., Edge, C.M., Hubbard, J.A., Nassau, P., McDowell, B., Skarzynski, T.J., Rowland, P., Somers, D.O., Kazmierski, W.M., Grimes, R.M., Wright, L.L., Smith, G.K., Zou, W., Wright, J., Pennicott, L.E.
登録日2010-04-23
公開日2010-06-02
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.02 Å)
主引用文献Synthesis and Evaluation of Novel Alpha-Amino Cyclic Boronates as Inhibitors of Hcv Ns3 Protease.
Bioorg.Med.Chem.Lett., 20, 2010
3OF7
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THE CRYSTAL STRUCTURE OF PRP20P FROM SACCHAROMYCES CEREVISIAE AND ITS BINDING PROPERTIES TO GSP1P AND HISTONES
分子名称:Regulator of chromosome condensation
著者Wu, F., Liu, Y., Zhu, Z., Huang, H., Ding, B., Wu, J., Shi, Y.
登録日2010-08-14
公開日2011-03-23
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The 1.9A crystal structure of Prp20p from Saccharomyces cerevisiae and its binding properties to Gsp1p and histones.
J.Struct.Biol., 174, 2011
3R7W
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CRYSTAL STRUCTURE OF GTR1P-GTR2P COMPLEX
分子名称:GTP-binding protein GTR1, GTP-binding protein GTR2, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
著者Gong, R., Li, L., Liu, Y., Wang, P., Yang, H., Wang, L., Cheng, J., Guan, K.L., Xu, Y.
登録日2011-03-23
公開日2011-08-24
最終更新日2013-06-19
実験手法X-RAY DIFFRACTION (2.773 Å)
主引用文献Crystal structure of the Gtr1p-Gtr2p complex reveals new insights into the amino acid-induced TORC1 activation
Genes Dev., 25, 2011
3SAL
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CRYSTAL STRUCTURE OF INFLUENZA A VIRUS NEURAMINIDASE N5
分子名称:Neuraminidase, CALCIUM ION, N-ACETYL-D-GLUCOSAMINE, ...
著者Wang, M.Y., Qi, J.X., Liu, Y., Vavricka, C.J., Wu, Y., Li, Q., Gao, G.F.
登録日2011-06-03
公開日2011-08-10
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Influenza a virus n5 neuraminidase has an extended 150-cavity
J.Virol., 85, 2011
3SAN
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CRYSTAL STRUCTURE OF INFLUENZA A VIRUS NEURAMINIDASE N5 COMPLEXED WITH ZANAMIVIR
分子名称:Neuraminidase, CALCIUM ION, N-ACETYL-D-GLUCOSAMINE, ...
著者Wang, M.Y., Qi, J.X., Liu, Y., Vavricka, C.J., Wu, Y., Li, Q., Gao, G.F.
登録日2011-06-03
公開日2011-08-10
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Influenza a virus n5 neuraminidase has an extended 150-cavity
J.Virol., 85, 2011
3U9G
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CRYSTAL STRUCTURE OF THE ZINC FINGER ANTIVIRAL PROTEIN
分子名称:Zinc finger CCCH-type antiviral protein 1, ZINC ION
著者Chen, S., Xu, Y., Zhang, K., Wang, X., Sun, J., Gao, G., Liu, Y.
登録日2011-10-18
公開日2012-03-14
最終更新日2013-07-17
実験手法X-RAY DIFFRACTION (1.801 Å)
主引用文献Structure of N-terminal domain of ZAP indicates how a zinc-finger protein recognizes complex RNA.
Nat.Struct.Mol.Biol., 19, 2012
4G1T
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CRYSTAL STRUCTURE OF INTERFERON-STIMULATED GENE 54
分子名称:Interferon-induced protein with tetratricopeptide repeats 2
著者Yang, Z., Liang, H., Zhou, Q., Li, Y., Chen, H., Ye, W., Chen, D., Fleming, J., Shu, H., Liu, Y.
登録日2012-07-11
公開日2012-08-15
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of ISG54 reveals a novel RNA binding structure and potential functional mechanisms.
Cell Res., 2012
4GJH
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CRYSTAL STRUCTURE OF THE TRAF DOMAIN OF TRAF5
分子名称:TNF receptor-associated factor 5
著者Zhang, P., Reichardt, A., Liang, H., Wang, Y., Cheng, D., Aliyari, R., Cheng, G., Liu, Y.
登録日2012-08-09
公開日2012-11-28
実験手法X-RAY DIFFRACTION (2.805 Å)
主引用文献Single Amino Acid Substitutions Confer the Antiviral Activity of the TRAF3 Adaptor Protein onto TRAF5
Sci.Signal., 5, 2012
4ITH
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CRYSTAL STRUCTURE OF RIP1 KINASE IN COMPLEX WITH NECROSTATIN-1 ANALOG
分子名称:Receptor-interacting serine/threonine-protein kinase 1, IODIDE ION, SODIUM ION, ...
著者Xie, T., Peng, W., Liu, Y., Yan, C., Shi, Y.
登録日2013-01-18
公開日2013-03-13
最終更新日2013-03-27
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structural Basis of RIP1 Inhibition by Necrostatins.
Structure, 21, 2013
4ITI
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CRYSTAL STRUCTURE OF RIP1 KINASE IN COMPLEX WITH NECROSTATIN-3 ANALOG
分子名称:Receptor-interacting serine/threonine-protein kinase 1, 1-{(3S,3aS)-3-[3-fluoro-4-(trifluoromethoxy)phenyl]-8-methoxy-3,3a,4,5-tetrahydro-2H-benzo[g]indazol-2-yl}-2-hydroxyethanone
著者Xie, T., Peng, W., Liu, Y., Yan, C., Shi, Y.
登録日2013-01-18
公開日2013-03-13
最終更新日2013-03-27
実験手法X-RAY DIFFRACTION (2.86 Å)
主引用文献Structural Basis of RIP1 Inhibition by Necrostatins.
Structure, 21, 2013
4ITJ
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CRYSTAL STRUCTURE OF RIP1 KINASE IN COMPLEX WITH NECROSTATIN-4
分子名称:Receptor-interacting serine/threonine-protein kinase 1, N-[(1S)-1-(2-chloro-6-fluorophenyl)ethyl]-5-cyano-1-methyl-1H-pyrrole-2-carboxamide, IODIDE ION
著者Xie, T., Peng, W., Liu, Y., Yan, C., Shi, Y.
登録日2013-01-18
公開日2013-03-13
最終更新日2013-03-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural Basis of RIP1 Inhibition by Necrostatins.
Structure, 21, 2013
4M7C
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CRYSTAL STRUCTURE OF THE TRF2-BINDING MOTIF OF SLX4 IN COMPLEX WITH THE TRFH DOMAIN OF TRF2
分子名称:Telomeric repeat-binding factor 2, Peptide from Structure-specific endonuclease subunit SLX4
著者Wan, B., Chen, Y., Wu, J., Liu, Y., Lei, M.
登録日2013-08-12
公開日2013-09-25
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献SLX4 Assembles a Telomere Maintenance Toolkit by Bridging Multiple Endonucleases with Telomeres
Cell Rep, 4, 2013
4QN3
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CRYSTAL STRUCTURE OF NEURAMINIDASE N7
分子名称:Neuraminidase, CALCIUM ION, N-ACETYL-D-GLUCOSAMINE, ...
著者Sun, X., Li, Q., Wu, Y., Liu, Y., Qi, J., Vavricka, C.J., Gao, G.F.
登録日2014-06-17
公開日2014-07-30
実験手法X-RAY DIFFRACTION (2.092 Å)
主引用文献Structure of influenza virus N7: the last piece of the neuraminidase "jigsaw" puzzle
J.Virol., 2014
4QN4
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CRYSTAL STRUCTURE OF NEURAMINIDASE N6
分子名称:Neuraminidase, CALCIUM ION, N-ACETYL-D-GLUCOSAMINE, ...
著者Sun, X., Li, Q., Wu, Y., Liu, Y., Qi, J., Vavricka, C.J., Gao, G.F.
登録日2014-06-17
公開日2014-07-30
最終更新日2014-08-06
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure of influenza virus N7: the last piece of the neuraminidase "jigsaw" puzzle
J.Virol., 2014
4QN5
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NEURAMINIDASE N5 BINDS LSTA AT THE SECOND SIA BINDING SITE
分子名称:Neuraminidase, CALCIUM ION, N-ACETYL-D-GLUCOSAMINE, ...
著者Sun, X., Li, Q., Wu, Y., Liu, Y., Qi, J., Vavricka, C.J., Gao, G.F.
登録日2014-06-17
公開日2014-07-30
最終更新日2014-08-06
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structure of influenza virus N7: the last piece of the neuraminidase "jigsaw" puzzle
J.Virol., 2014
4QN6
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CRYSTAL STRUCTURE OF NEURAMINIDASE N6 COMPLEXED WITH LANINAMIVIR
分子名称:Neuraminidase, CALCIUM ION, N-ACETYL-D-GLUCOSAMINE, ...
著者Sun, X., Li, Q., Wu, Y., Liu, Y., Qi, J., Vavricka, C.J., Gao, G.F.
登録日2014-06-17
公開日2014-07-30
最終更新日2014-08-06
実験手法X-RAY DIFFRACTION (1.945 Å)
主引用文献Structure of influenza virus N7: the last piece of the neuraminidase "jigsaw" puzzle
J.Virol., 2014
4QN7
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CRYSTAL STRUCTURE OF NEURAMNIDASE N7 COMPLEXED WITH OSELTAMIVIR
分子名称:Neuraminidase, CALCIUM ION, N-ACETYL-D-GLUCOSAMINE, ...
著者Sun, X., Li, Q., Wu, Y., Liu, Y., Qi, J., Vavricka, C.J., Gao, G.F.
登録日2014-06-17
公開日2014-07-30
最終更新日2014-08-06
実験手法X-RAY DIFFRACTION (2.302 Å)
主引用文献Structure of influenza virus N7: the last piece of the neuraminidase "jigsaw" puzzle
J.Virol., 2014