Author results

2WCA
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BTGH84 IN COMPLEX WITH N-BUTYL PUGNAC
Descriptor:O-GLCNACASE BT_4395, [[(3R,4R,5S,6R)-3-(BUTANOYLAMINO)-4,5-DIHYDROXY-6-(HYDROXYMETHYL)OXAN-2-YLIDENE]AMINO] N-PHENYLCARBAMATE, CALCIUM ION
Authors:He, Y., Davies, G.J.
Deposit date:2009-03-10
Release date:2009-06-16
Last modified:2017-03-29
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Insight Into a Strategy for Attenuating Ampc- Mediated Beta-Lactam Resistance: Structural Basis for Selective Inhibition of the Glycoside Hydrolase Nagz.
Protein Sci., 18, 2009
2WHJ
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UNDERSTANDING HOW DIVERSE MANNANASES RECOGNISE HETEROGENEOUS SUBSTRATES
Descriptor:BETA-MANNANASE, GLYCEROL, ACETATE ION, ...
Authors:Tailford, L.E., Ducros, V.M.A., Flint, J.E., Roberts, S.M., Morland, C., Zechel, D.L., Smith, N., Bjornvad, M.E., Borchert, T.V., Wilson, K.S., Davies, G.J., Gilbert, H.J.
Deposit date:2009-05-05
Release date:2009-05-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Understanding How Diverse -Mannanases Recognise Heterogeneous Substrates.
Biochemistry, 48, 2009
2WHK
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STRUCTURE OF BACILLUS SUBTILIS MANNANASE MAN26
Descriptor:MANNAN ENDO-1,4-BETA-MANNOSIDASE, GLYCEROL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ...
Authors:Ducros, V.M.A., Davies, G.J.
Deposit date:2009-05-05
Release date:2009-05-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Understanding How Diverse -Mannanases Recognise Heterogeneous Substrates.
Biochemistry, 48, 2009
2WHL
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UNDERSTANDING HOW DIVERSE MANNANASES RECOGNISE HETEROGENEOUS SUBSTRATES
Descriptor:BETA-MANNANASE, ACETATE ION, ALPHA-D-MANNOSE, ...
Authors:Tailford, L.E., Ducros, V.M.A., Flint, J.E., Roberts, S.M., Morland, C., Zechel, D.L., Smith, N., Bjornvad, M.E., Borchert, T.V., Wilson, K.S., Davies, G.J., Gilbert, H.J.
Deposit date:2009-05-05
Release date:2009-05-26
Last modified:2012-11-28
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Understanding How Diverse -Mannanases Recognise Heterogeneous Substrates.
Biochemistry, 48, 2009
2WHM
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CELLVIBRIO JAPONICUS MAN26A E121A AND E320G DOUBLE MUTANT IN COMPLEX WITH MANNOBIOSE
Descriptor:ENDO-1,4-BETA MANNANASE, MAN26A, ZINC ION, ...
Authors:Durcos, V.M.A., Davies, G.J., Flint, J.E., Gilbert, H.J.
Deposit date:2009-05-05
Release date:2009-05-26
Last modified:2015-03-18
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Understanding How Diverse -Mannanases Recognise Heterogeneous Substrates.
Biochemistry, 48, 2009
2WK2
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CHITINASE A FROM SERRATIA MARCESCENS ATCC990 IN COMPLEX WITH CHITOTRIO-THIAZOLINE DITHIOAMIDE.
Descriptor:CHITINASE A, 2-deoxy-2-(ethanethioylamino)-beta-D-glucopyranose, 3AR,5R,6S,7R,7AR-5-HYDROXYMETHYL-2-METHYL-5,6,7,7A-TETRAHYDRO-3AH-PYRANO[3,2-D]THIAZOLE-6,7-DIOL, ...
Authors:Taylor, E.J., Dennis, R.J., Macdonald, J.M., Tarling, C.A., Knapp, S., Withers, S.G., Davies, G.J.
Deposit date:2009-06-04
Release date:2010-03-16
Last modified:2011-10-12
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Chitinase Inhibition by Chitobiose and Chitotriose Thiazolines.
Angew.Chem.Int.Ed.Engl., 49, 2010
2WLY
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CHITINASE A FROM SERRATIA MARCESCENS ATCC990 IN COMPLEX WITH CHITOTRIO-THIAZOLINE.
Descriptor:Chitinase, 1,4-DIETHYLENE DIOXIDE, DI(HYDROXYETHYL)ETHER, ...
Authors:Taylor, E.J., Dennis, R.J., Macdonald, J.M., Tarling, C.A., Knapp, S., Withers, S.G., Davies, G.J.
Deposit date:2009-06-29
Release date:2010-03-16
Last modified:2018-12-12
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Chitinase inhibition by chitobiose and chitotriose thiazolines.
Angew. Chem. Int. Ed. Engl., 49, 2010
2WLZ
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CHITINASE A FROM SERRATIA MARCESCENS ATCC990 IN COMPLEX WITH CHITOBIO- THIAZOLINE.
Descriptor:CHITINASE A, 1,4-DIETHYLENE DIOXIDE, DI(HYDROXYETHYL)ETHER, ...
Authors:Taylor, E.J., Dennis, R.J., Macdonald, J.M., Tarling, C.A., Knapp, S., Withers, S.G., Davies, G.J.
Deposit date:2009-06-29
Release date:2010-03-16
Last modified:2011-10-12
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:Chitinase Inhibition by Chitobiose and Chitotriose Thiazolines.
Angew.Chem.Int.Ed.Engl., 49, 2010
2WM0
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CHITINASE A FROM SERRATIA MARCESCENS ATCC990 IN COMPLEX WITH CHITOBIO- THIAZOLINE THIOAMIDE.
Descriptor:CHITINASE A, N-ACETYL-D-GLUCOSAMINE, 3AR,5R,6S,7R,7AR-5-HYDROXYMETHYL-2-METHYL-5,6,7,7A-TETRAHYDRO-3AH-PYRANO[3,2-D]THIAZOLE-6,7-DIOL, ...
Authors:Taylor, E.J., Dennis, R.J., Macdonald, J.M., Tarling, C.A., Knapp, S., Withers, S.G., Davies, G.J.
Deposit date:2009-06-29
Release date:2010-03-16
Last modified:2011-10-12
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Chitinase Inhibition by Chitobiose and Chitotriose Thiazolines.
Angew.Chem.Int.Ed.Engl., 49, 2010
2WTX
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INSIGHT INTO THE MECHANISM OF ENZYMATIC GLYCOSYLTRANSFER WITH RETENTION THROUGH THE SYNTHESIS AND ANALYSIS OF BISUBSTRATE GLYCOMIMETICS OF TREHALOSE-6-PHOSPHATE SYNTHASE
Descriptor:ALPHA, ALPHA-TREHALOSE-PHOSPHATE SYNTHASE [UDP-FORMING], 1,2-ETHANEDIOL, ...
Authors:Errey, J.C., Lee, S.S., Gibson, R.P., Martinez-Fleites, C., Barry, C.S., Jung, P.M.J., OSullivan, A., Davis, B.G., Davies, G.J.
Deposit date:2009-09-25
Release date:2010-02-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Mechanistic Insight Into Enzymatic Glycosyl Transfer with Retention of Configuration Through Analysis of Glycomimetic Inhibitors.
Angew.Chem.Int.Ed.Engl., 49, 2010
2WVS
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CRYSTAL STRUCTURE OF AN ALPHA-L-FUCOSIDASE GH29 TRAPPED COVALENT INTERMEDIATE FROM BACTEROIDES THETAIOTAOMICRON IN COMPLEX WITH 2- FLUORO-FUCOSYL FLUORIDE USING AN E288Q MUTANT
Descriptor:ALPHA-L-FUCOSIDASE, 2-DEOXY-2-FLUORO-BETA-L-FUCOPYRANOSE, SULFATE ION
Authors:Lammerts van Bueren, A., Ardevol, A., Fayers-Kerr, J., Luo, B., Zhang, Y., Sollogoub, M., Bleriot, Y., Rovira, C., Davies, G.J.
Deposit date:2009-10-20
Release date:2010-02-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:Analysis of the Reaction Coordinate of Alpha-L-Fucosidases: A Combined Structural and Quantum Mechanical Approach
J.Am.Chem.Soc., 132, 2010
2WVT
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CRYSTAL STRUCTURE OF AN ALPHA-L-FUCOSIDASE GH29 FROM BACTEROIDES THETAIOTAOMICRON IN COMPLEX WITH A NOVEL IMINOSUGAR FUCOSIDASE INHIBITOR
Descriptor:ALPHA-L-FUCOSIDASE, (2S,3R,5R,6S)-3,4,5-TRIHYDROXY-2,6-BIS(HYDROXYMETHYL)PIPERIDINIUM, GLYCEROL, ...
Authors:Lammerts van Bueren, A., Ardevol, A., Fayers-Kerr, J., Luo, B., Zhang, Y., Sollogoub, M., Bleriot, Y., Rovira, C., Davies, G.J.
Deposit date:2009-10-20
Release date:2010-02-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Analysis of the Reaction Coordinate of Alpha-L-Fucosidases: A Combined Structural and Quantum Mechanical Approach.
J.Am.Chem.Soc., 132, 2010
2WVU
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CRYSTAL STRUCTURE OF A MICHAELIS COMPLEX OF ALPHA-L-FUCOSIDASE GH29 FROM BACTEROIDES THETAIOTAOMICRON WITH THE SYNTHETIC SUBSTRATE 4- NITROPHENYL-ALPHA-L-FUCOSE
Descriptor:ALPHA-L-FUCOSIDASE, SULFATE ION, 4-nitrophenyl-alpha-L-fucose
Authors:Lammerts van Bueren, A., Ardevol, A., Fayers-Kerr, J., Luo, B., Zhang, Y., Sollogoub, M., Bleriot, Y., Rovira, C., Davies, G.J.
Deposit date:2009-10-20
Release date:2010-02-02
Last modified:2019-02-27
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Analysis of the Reaction Coordinate of Alpha-L-Fucosidases: A Combined Structural and Quantum Mechanical Approach
J.Am.Chem.Soc., 132, 2010
2WVV
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CRYSTAL STRUCTURE OF AN ALPHA-L-FUCOSIDASE GH29 FROM BACTEROIDES THETAIOTAOMICRON
Descriptor:ALPHA-L-FUCOSIDASE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, SULFATE ION, ...
Authors:Lammerts van Bueren, A., Ardevol, A., Fayers-Kerr, J., Luo, B., Zhang, Y., Sollogoub, M., Bleriot, Y., Rovira, C., Davies, G.J.
Deposit date:2009-10-20
Release date:2010-02-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Analysis of the Reaction Coordinate of Alpha-L-Fucosidases: A Combined Structural and Quantum Mechanical Approach
J.Am.Chem.Soc., 132, 2010
2WVX
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STRUCTURE OF THE FAMILY GH92 INVERTING MANNOSIDASE BT3990 FROM BACTEROIDES THETAIOTAOMICRON VPI-5482
Descriptor:PUTATIVE ALPHA-1,2-MANNOSIDASE, CALCIUM ION, GLYCEROL
Authors:Suits, M.D.L., Zhu, Y., Thompson, A., Gilbert, H.J., Davies, G.J.
Deposit date:2009-10-21
Release date:2009-11-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Mechanistic Insights Into a Ca2+-Dependent Family of A-Mannosidases in a Human Gut Symbiont.
Nat.Chem.Biol., 6, 2010
2WVY
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STRUCTURE OF THE FAMILY GH92 INVERTING MANNOSIDASE BT2199 FROM BACTEROIDES THETAIOTAOMICRON VPI-5482
Descriptor:ALPHA-1,2-MANNOSIDASE
Authors:Suits, M.D.L., Zhu, Y., Thompson, A., Gilbert, H.J., Davies, G.J.
Deposit date:2009-10-21
Release date:2009-11-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Mechanistic Insights Into a Ca2+-Dependent Family of A-Mannosidases in a Human Gut Symbiont.
Nat.Chem.Biol., 6, 2010
2WVZ
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STRUCTURE OF THE FAMILY GH92 INVERTING MANNOSIDASE BT3990 FROM BACTEROIDES THETAIOTAOMICRON VPI-5482
Descriptor:PUTATIVE ALPHA-1,2-MANNOSIDASE, CALCIUM ION, KIFUNENSINE, ...
Authors:Suits, M.D.L., Zhu, Y., Thompson, A., Gilbert, H.J., Davies, G.J.
Deposit date:2009-10-21
Release date:2009-12-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Mechanistic Insights Into a Ca2+-Dependent Family of A-Mannosidases in a Human Gut Symbiont.
Nat.Chem.Biol., 6, 2010
2WW0
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STRUCTURE OF THE FAMILY GH92 INVERTING MANNOSIDASE BT3990 FROM BACTEROIDES THETAIOTAOMICRON VPI-5482
Descriptor:PUTATIVE ALPHA-1,2-MANNOSIDASE, CALCIUM ION, 1S-8AB-OCTAHYDRO-INDOLIZIDINE-1A,2A,8B-TRIOL, ...
Authors:Suits, M.D.L., Thompson, A., Zhu, Y., Gilbert, H.J., Davies, G.J.
Deposit date:2009-10-21
Release date:2009-12-29
Last modified:2013-05-22
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Mechanistic Insights Into a Ca2+-Dependent Family of A-Mannosidases in a Human Gut Symbiont.
Nat.Chem.Biol., 6, 2010
2WW1
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STRUCTURE OF THE FAMILY GH92 INVERTING MANNOSIDASE BT3990 FROM BACTEROIDES THETAIOTAOMICRON VPI-5482 IN COMPLEX WITH THIOMANNOBIOSIDE
Descriptor:PUTATIVE ALPHA-1,2-MANNOSIDASE, METHYL-2-S-(ALPHA-D-MANNOPYRANOSYL)-2-THIO-ALPHA-D-MANNOPYRANOSIDE
Authors:Suits, M.D.L., Zhu, Y., Thompson, A., Gilbert, H.J., Davies, G.J.
Deposit date:2009-10-21
Release date:2009-12-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Mechanistic Insights Into a Ca2+-Dependent Family of A-Mannosidases in a Human Gut Symbiont.
Nat.Chem.Biol., 6, 2010
2WW2
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STRUCTURE OF THE FAMILY GH92 INVERTING MANNOSIDASE BT2199 FROM BACTEROIDES THETAIOTAOMICRON VPI-5482
Descriptor:ALPHA-1,2-MANNOSIDASE, (4S)-2-METHYL-2,4-PENTANEDIOL, SODIUM ION, ...
Authors:Suits, M.D.L., Zhu, Y., Thompson, A., Gilbert, H.J., Davies, G.J.
Deposit date:2009-10-21
Release date:2009-12-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Mechanistic Insights Into a Ca2+-Dependent Family of A-Mannosidases in a Human Gut Symbiont.
Nat.Chem.Biol., 6, 2010
2WW3
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STRUCTURE OF THE FAMILY GH92 INVERTING MANNOSIDASE BT3990 FROM BACTEROIDES THETAIOTAOMICRON VPI-5482 IN COMPLEX WITH THIOMANNOBIOSIDE
Descriptor:PUTATIVE ALPHA-1,2-MANNOSIDASE, CALCIUM ION, METHYL-2-S-(ALPHA-D-MANNOPYRANOSYL)-2-THIO-ALPHA-D-MANNOPYRANOSIDE, ...
Authors:Suits, M.D.L., Zhu, Y., Thompson, A.J., Gilbert, H.J., Davies, G.J.
Deposit date:2009-10-21
Release date:2010-01-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Mechanistic Insights Into a Ca(2+)-Dependent Family of Alpha-Mannosidases in a Human Gut Symbiont.
Nat.Chem.Biol., 6, 2010
2WYH
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STRUCTURE OF THE STREPTOCOCCUS PYOGENES FAMILY GH38 ALPHA-MANNOSIDASE
Descriptor:ALPHA-MANNOSIDASE, ZINC ION, GLYCEROL, ...
Authors:Suits, M.D.L., Zhu, Y., Taylor, E.J., Zechel, D.L., Gilbert, H.J., Davies, G.J.
Deposit date:2009-11-16
Release date:2010-02-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure and Kinetic Investigation of Streptococcus Pyogenes Family Gh38 Alpha-Mannosidase
Plos One, 5, 2010
2WYI
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STRUCTURE OF THE STREPTOCOCCUS PYOGENES FAMILY GH38 ALPHA-MANNOSIDASE COMPLEXED WITH SWAINSONINE
Descriptor:ALPHA-MANNOSIDASE, 2-(2-METHOXYETHOXY)ETHANOL, ZINC ION, ...
Authors:Suits, M.D.L., Zhu, Y., Taylor, E.J., Zechel, D.L., Gilbert, H.J., Davies, G.J.
Deposit date:2009-11-16
Release date:2010-02-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure and Kinetic Investigation of Streptococcus Pyogenes Family Gh38 Alpha-Mannosidase
Plos One, 5, 2010
2WYN
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STRUCTURE OF FAMILY 37 TREHALASE FROM ESCHERICHIA COLI IN COMPLEX WITH A CASUARINE-6-O-A-D-GLUCOSIDE ANALOGUE
Descriptor:PERIPLASMIC TREHALASE, (1R,2R,3R,6R,7R,7AR)-3,7-BIS(HYDROXYMETHYL)HEXAHYDRO-1H-PYRROLIZINE-1,2,6-TRIOL, ALPHA-D-GLUCOSE, ...
Authors:Gloster, T.M., Roberts, S.M., Davies, G.J., Cardona, F., Goti, A., Parmeggiani, C., Parenti, P., Fusi, P., Forcella, M., Cipolla, L.
Deposit date:2009-11-17
Release date:2010-09-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Casuarine-6-O-Alpha-D-Glucoside and its Analogues are Tight Binding Inhibitors of Insect and Bacterial Trehalases.
Chem.Commun.(Camb.), 46, 2010
2WZ8
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FAMILY 35 CARBOHYDRATE BINDING MODULE FROM CLOSTRIDIUM THERMOCELLUM
Descriptor:CELLULOSOME PROTEIN DOCKERIN TYPE I, CALCIUM ION, MAGNESIUM ION
Authors:Gloster, T.M., Davies, G.J., Fontes, C.M., Gilbert, H.J.
Deposit date:2009-11-25
Release date:2010-07-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Signature Active Site Architectures Illuminate the Molecular Basis for Ligand Specificity in Family 35 Carbohydrate Binding Module .
Biochemistry, 49, 2010