1CGM
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1BPR
| NMR STRUCTURE OF THE SUBSTRATE BINDING DOMAIN OF DNAK, MINIMIZED AVERAGE STRUCTURE | Descriptor: | DNAK | Authors: | Wang, H, Kurochkin, A.V, Pang, Y, Hu, W, Flynn, G.C, Zuiderweg, E.R.P. | Deposit date: | 1998-08-11 | Release date: | 1999-03-02 | Last modified: | 2022-02-16 | Method: | SOLUTION NMR | Cite: | NMR solution structure of the 21 kDa chaperone protein DnaK substrate binding domain: a preview of chaperone-protein interaction. Biochemistry, 37, 1998
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4RGW
| Crystal Structure of a TAF1-TAF7 Complex in Human Transcription Factor IID | Descriptor: | GLYCEROL, Transcription initiation factor TFIID subunit 1, Transcription initiation factor TFIID subunit 7 | Authors: | Wang, H, Curran, E.C, Hinds, T.R, Wang, E.H, Zheng, N. | Deposit date: | 2014-09-30 | Release date: | 2014-12-03 | Last modified: | 2014-12-17 | Method: | X-RAY DIFFRACTION (2.301 Å) | Cite: | Crystal structure of a TAF1-TAF7 complex in human transcription factor IID reveals a promoter binding module. Cell Res., 24, 2014
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6TYD
| Structure of human LDB1 in complex with SSBP2 | Descriptor: | LIM domain-binding protein 1, Single-stranded DNA-binding protein 2 | Authors: | Wang, H, Wang, Z, Xu, W. | Deposit date: | 2019-08-08 | Release date: | 2020-01-01 | Last modified: | 2020-01-29 | Method: | X-RAY DIFFRACTION (2.803 Å) | Cite: | Crystal structure of human LDB1 in complex with SSBP2. Proc.Natl.Acad.Sci.USA, 117, 2020
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8BZN
| SARS-CoV-2 non-structural protein 10 (nsp10) variant T102I | Descriptor: | CHLORIDE ION, DIMETHYL SULFOXIDE, Replicase polyprotein 1ab, ... | Authors: | Wang, H, Rizvi, S.R.A, Dong, D, Lou, J, Wang, Q, Sopipong, W, Najar, F, Agarwal, P.K, Kozielski, F, Haider, S. | Deposit date: | 2022-12-15 | Release date: | 2023-12-27 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.19 Å) | Cite: | Emerging variants of SARS-CoV-2 NSP10 highlight strong functional conservation of its binding to two non-structural proteins, NSP14 and NSP16. Elife, 12, 2023
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6T9K
| SAGA Core module | Descriptor: | Protein SPT3, SAGA-associated factor 73, Transcription factor SPT20, ... | Authors: | Wang, H, Cheung, A, Cramer, P. | Deposit date: | 2019-10-28 | Release date: | 2020-01-29 | Last modified: | 2020-02-19 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structure of the transcription coactivator SAGA. Nature, 577, 2020
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6T9J
| SAGA Tra1 module | Descriptor: | Transcription factor SPT20, Transcription initiation factor TFIID subunit 12, Transcription-associated protein 1 | Authors: | Wang, H, Cheung, A, Cramer, P. | Deposit date: | 2019-10-28 | Release date: | 2020-01-29 | Last modified: | 2020-02-19 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structure of the transcription coactivator SAGA. Nature, 577, 2020
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6T9I
| cryo-EM structure of transcription coactivator SAGA | Descriptor: | Protein SPT3, SAGA-associated factor 73, Transcription factor SPT20, ... | Authors: | Wang, H, Cheung, A, Cramer, P. | Deposit date: | 2019-10-28 | Release date: | 2020-01-29 | Last modified: | 2020-02-19 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Structure of the transcription coactivator SAGA. Nature, 577, 2020
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6T9L
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6HBA
| Crystal Structure of the small subunit-like domain 1 of CcmM from Synechococcus elongatus (strain PCC 7942), thiol-oxidized form | Descriptor: | Carbon dioxide concentrating mechanism protein CcmM | Authors: | Wang, H, Yan, X, Aigner, H, Bracher, A, Nguyen, N.D, Hee, W.Y, Long, B.M, Price, G.D, Hartl, F.U, Hayer-Hartl, M. | Deposit date: | 2018-08-10 | Release date: | 2018-12-12 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Rubisco condensate formation by CcmM in beta-carboxysome biogenesis. Nature, 566, 2019
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6HBC
| Structure of the repeat unit in the network formed by CcmM and Rubisco from Synechococcus elongatus | Descriptor: | Carbon dioxide concentrating mechanism protein CcmM, Ribulose 1,5-bisphosphate carboxylase small subunit, Ribulose bisphosphate carboxylase large chain | Authors: | Wang, H, Yan, X, Aigner, H, Bracher, A, Nguyen, N.D, Hee, W.Y, Long, B.M, Price, G.D, Hartl, F.U, Hayer-Hartl, M. | Deposit date: | 2018-08-10 | Release date: | 2018-12-12 | Last modified: | 2019-02-20 | Method: | ELECTRON MICROSCOPY (2.78 Å) | Cite: | Rubisco condensate formation by CcmM in beta-carboxysome biogenesis. Nature, 566, 2019
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8B38
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8B3J
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8B4Z
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8B59
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6S01
| Structure of LEDGF PWWP domain bound H3K36 methylated nucleosome | Descriptor: | Histone H2A, Histone H2B 1.1, Histone H3, ... | Authors: | Wang, H, Farnung, L, Dienemann, C, Cramer, P. | Deposit date: | 2019-06-13 | Release date: | 2019-12-18 | Last modified: | 2020-01-22 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structure of H3K36-methylated nucleosome-PWWP complex reveals multivalent cross-gyre binding. Nat.Struct.Mol.Biol., 27, 2020
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7OS7
| Circular permutant of ribosomal protein S6, swap helix 2, L75A, A92K mutant | Descriptor: | 30S ribosomal protein S6,30S ribosomal protein S6 | Authors: | Wang, H, Logan, D.T, Oliveberg, M. | Deposit date: | 2021-06-08 | Release date: | 2022-06-22 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Circular permutant of ribosomal protein S6, swap helix 2, L75A, A92K mutant To Be Published
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6VCD
| Cryo-EM structure of IRP2-FBXL5-SKP1 complex | Descriptor: | F-box/LRR-repeat protein 5, FE2/S2 (INORGANIC) CLUSTER, Iron-responsive element binding protein 2, ... | Authors: | Wang, H, Shi, H, Zheng, N. | Deposit date: | 2019-12-20 | Release date: | 2020-08-05 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | FBXL5 Regulates IRP2 Stability in Iron Homeostasis via an Oxygen-Responsive [2Fe2S] Cluster. Mol.Cell, 78, 2020
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1FBN
| CRYSTAL STRUCTURE OF A FIBRILLARIN HOMOLOGUE FROM METHANOCOCCUS JANNASCHII, A HYPERTHERMOPHILE, AT 1.6 A | Descriptor: | MJ FIBRILLARIN HOMOLOGUE | Authors: | Wang, H, Boisvert, D, Kim, K.K, Kim, R, Kim, S.H, Berkeley Structural Genomics Center (BSGC) | Deposit date: | 1999-04-25 | Release date: | 2000-04-26 | Last modified: | 2014-11-26 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Crystal structure of a fibrillarin homologue from Methanococcus jannaschii, a hyperthermophile, at 1.6 A resolution. EMBO J., 19, 2000
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1ZKL
| Multiple Determinants for Inhibitor Selectivity of Cyclic Nucleotide Phosphodiesterases | Descriptor: | 3-ISOBUTYL-1-METHYLXANTHINE, High-affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A, MAGNESIUM ION, ... | Authors: | Wang, H, Liu, Y, Chen, Y, Robinson, H, Ke, H. | Deposit date: | 2005-05-03 | Release date: | 2005-07-05 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.67 Å) | Cite: | Multiple elements jointly determine inhibitor selectivity of cyclic nucleotide phosphodiesterases 4 and 7 J.Biol.Chem., 280, 2005
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5IZ5
| Human GIVD cytosolic phospholipase A2 | Descriptor: | Cytosolic phospholipase A2 delta, SULFATE ION | Authors: | Wang, H, Klein, M.G. | Deposit date: | 2016-03-24 | Release date: | 2016-06-08 | Last modified: | 2016-06-22 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure of Human GIVD Cytosolic Phospholipase A2 Reveals Insights into Substrate Recognition. J.Mol.Biol., 428, 2016
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5IZR
| Human GIVD cytosolic phospholipase A2 in complex with Methyl gamma-Linolenyl Fluorophosphonate inhibitor and Terbium Chloride | Descriptor: | Cytosolic phospholipase A2 delta, TERBIUM(III) ION, methyl (R)-(6Z,9Z,12Z)-octadeca-6,9,12-trien-1-ylphosphonofluoridate | Authors: | Wang, H, Klein, M.G. | Deposit date: | 2016-03-25 | Release date: | 2016-06-08 | Last modified: | 2016-06-22 | Method: | X-RAY DIFFRACTION (3.25 Å) | Cite: | Structure of Human GIVD Cytosolic Phospholipase A2 Reveals Insights into Substrate Recognition. J.Mol.Biol., 428, 2016
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5IXC
| Human GIVD cytosolic phospholipase A2 in complex with Methyl gamma-Linolenyl Fluorophosphonate | Descriptor: | BARIUM ION, Cytosolic phospholipase A2 delta, methyl (R)-(6Z,9Z,12Z)-octadeca-6,9,12-trien-1-ylphosphonofluoridate | Authors: | Wang, H, Klein, M.G. | Deposit date: | 2016-03-23 | Release date: | 2016-06-08 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Structure of Human GIVD Cytosolic Phospholipase A2 Reveals Insights into Substrate Recognition. J.Mol.Biol., 428, 2016
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1WWI
| Crystal structure of ttk003001566 from Thermus Thermophilus HB8 | Descriptor: | hypothetical protein TTHA1479 | Authors: | Wang, H, Murayama, K, Terada, T, Chen, L, Liu, Z.J, Wang, B.C, Shirouzu, M, Kuramitsu, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2005-01-05 | Release date: | 2005-07-05 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.58 Å) | Cite: | Crystal structure of ttk003001566 from Thermus Thermophilus HB8 TO BE PUBLISHED
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3ECN
| Crystal structure of PDE8A catalytic domain in complex with IBMX | Descriptor: | 3-ISOBUTYL-1-METHYLXANTHINE, High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A, MAGNESIUM ION, ... | Authors: | Wang, H, Yan, Z, Yang, S, Cai, J, Robinson, H, Ke, H. | Deposit date: | 2008-09-01 | Release date: | 2008-11-25 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Kinetic and structural studies of phosphodiesterase-8A and implication on the inhibitor selectivity Biochemistry, 47, 2008
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