Author results

1FT4
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PHOTOCHEMICALLY-ENHANCED BINDING OF SMALL MOLECULES TO THE TUMOR NECROSIS FACTOR RECEPTOR-1
分子名称:SOLUBLE TUMOR NECROSIS FACTOR RECEPTOR 1, 5-(3-MORPHOLIN-4-YL-PROPYL)-2-(3-NITRO-PHENYL)-4-THIOXO-4,5-DIHYDRO-1-THIA-3B,5-DIAZA-CYCLOPENTA[A]PENTALEN-6-ONE
著者Muckelbauer, J.K., Chang, C.-H.
登録日2000-09-11
公開日2001-10-12
最終更新日2017-10-04
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Photochemically enhanced binding of small molecules to the tumor necrosis factor receptor-1 inhibits the binding of TNF-alpha.
Proc.Natl.Acad.Sci.USA, 98, 2001
1NW3
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STRUCTURE OF THE CATALYTIC DOMAIN OF HUMAN DOT1L, A NON-SET DOMAIN NUCLEOSOMAL HISTONE METHYLTRANSFERASE
分子名称:histone methyltransferase DOT1L, ACETATE ION, SULFATE ION, ...
著者Min, J.R., Feng, Q., Li, Z.H., Zhang, Y., Xu, R.M.
登録日2003-02-05
公開日2003-03-25
最終更新日2014-04-16
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure of the Catalytic domain of human DOT1L, a non-SET domain nucleosomal histone methyltransferase
Cell(Cambridge,Mass.), 112, 2003
2HV6
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CRYSTAL STRUCTURE OF THE PHOSPHOTYROSYL PHOSPHATASE ACTIVATOR
分子名称:Protein phosphatase 2A, regulatory subunit B, MAGNESIUM ION
著者Chao, Y., Jeffrey, P.D., Shi, Y.
登録日2006-07-27
公開日2006-08-22
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure and mechanism of the phosphotyrosyl phosphatase activator.
Mol.Cell, 23, 2006
2HV7
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CRYSTAL STRUCTURE OF PHOSPHOTYROSYL PHOSPHATASE ACTIVATOR BOUND TO ATPGAMMAS
分子名称:Protein phosphatase 2A, regulatory subunit B, ADENOSINE-5'-DIPHOSPHATE
著者Chao, Y., Jeffrey, J.D., Shi, Y.
登録日2006-07-27
公開日2006-08-22
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure and mechanism of the phosphotyrosyl phosphatase activator.
Mol.Cell, 23, 2006
2IE3
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STRUCTURE OF THE PROTEIN PHOSPHATASE 2A CORE ENZYME BOUND TO TUMOR-INDUCING TOXINS
分子名称:Protein Phosphatase 2, regulatory subunit A (PR 65), alpha isoform, ...
著者Xing, Y., Xu, Y., Chen, Y., Jeffrey, P.D., Chao, Y., Shi, Y.
登録日2006-09-17
公開日2006-11-07
最終更新日2013-02-27
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of Protein Phosphatase 2A Core Enzyme Bound to Tumor-Inducing Toxins
Cell(Cambridge,Mass.), 127, 2006
2IE4
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STRUCTURE OF THE PROTEIN PHOSPHATASE 2A CORE ENZYME BOUND TO OKADAIC ACID
分子名称:Protein Phosphatase 2, regulatory subunit A (PR 65), alpha isoform, ...
著者Xing, Y., Xu, Y., Chen, Y., Jeffrey, P.D., Chao, Y., Shi, Y.
登録日2006-09-17
公開日2006-11-07
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure of Protein Phosphatase 2A Core Enzyme Bound to Tumor-Inducing Toxins
Cell(Cambridge,Mass.), 127, 2006
2PKG
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STRUCTURE OF A COMPLEX BETWEEN THE A SUBUNIT OF PROTEIN PHOSPHATASE 2A AND THE SMALL T ANTIGEN OF SV40
分子名称:Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform, Small T antigen, ZINC ION
著者Jeffrey, P.D., Shi, Y.
登録日2007-04-17
公開日2007-05-15
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structural and biochemical insights into the regulation of protein phosphatase 2A by small t antigen of SV40.
Nat.Struct.Mol.Biol., 14, 2007
2Q06
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CRYSTAL STRUCTURE OF INFLUENZA A VIRUS H5N1 NUCLEOPROTEIN
分子名称:Nucleoprotein
著者Ng, A.K.L., Zhang, H., Tan, K., Wang, J., Shaw, P.C.
登録日2007-05-21
公開日2008-05-27
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structure of the influenza virus A H5N1 nucleoprotein: implications for RNA binding, oligomerization, and vaccine design.
Faseb J., 22, 2008
3GAK
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STRUCTURE OF GIARDIA FRUCTOSE-1,6-BIPHOSPHATE ALDOLASE
分子名称:Fructose-bisphosphate aldolase, ZINC ION, SULFATE ION
著者Galkin, A., Herzberg, O.
登録日2009-02-17
公開日2009-03-31
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural insights into the substrate binding and stereoselectivity of giardia fructose-1,6-bisphosphate aldolase.
Biochemistry, 48, 2009
3GAY
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STRUCTURE OF GIARDIA FRUCTOSE-1,6-BIPHOSPHATE ALDOLASE IN COMPLEX WITH TAGATOSE-1,6-BIPHOSPHATE
分子名称:Fructose-bisphosphate aldolase, ZINC ION, 1,6-di-O-phosphono-D-tagatose
著者Galkin, A., Herzberg, O.
登録日2009-02-18
公開日2009-03-31
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural insights into the substrate binding and stereoselectivity of giardia fructose-1,6-bisphosphate aldolase.
Biochemistry, 48, 2009
3GB6
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STRUCTURE OF GIARDIA FRUCTOSE-1,6-BIPHOSPHATE ALDOLASE D83A MUTANT IN COMPLEX WITH FRUCTOSE-1,6-BISPHOSPHATE
分子名称:Fructose-bisphosphate aldolase, ZINC ION, 1,6-di-O-phosphono-D-fructose
著者Galkin, A., Herzberg, O.
登録日2009-02-18
公開日2009-03-31
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural insights into the substrate binding and stereoselectivity of giardia fructose-1,6-bisphosphate aldolase.
Biochemistry, 48, 2009
3IEI
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CRYSTAL STRUCTURE OF HUMAN LEUCINE CARBOXYLMETHYLTRANSFERASE-1 IN COMPLEX WITH S-ADENOSYL HOMOCYSTEINE
分子名称:Leucine carboxyl methyltransferase 1, S-ADENOSYL-L-HOMOCYSTEINE, GLYCEROL, ...
著者Xing, Y., Jeffry, P.D.
登録日2009-07-22
公開日2010-08-11
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural Insights into Novel Functions of a pro-survival PP2A-specific Methyltransferase
To be Published
3JCT
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CRYO-EM STRUCTURE OF EUKARYOTIC PRE-60S RIBOSOMAL SUBUNITS
分子名称:60S ribosomal protein L2-A, 60S ribosomal protein L3, 60S ribosomal protein L4-A, ...
著者Wu, S., Kumcuoglu, B., Yan, K.G., Brown, H., Zhang, Y.X., Tan, D., Gamalinda, M., Yuan, Y., Li, Z.F., Jakovljevic, J., Ma, C.Y., Lei, J.L., Dong, M.Q., Woolford Jr., J.L., Gao, N.
登録日2016-03-09
公開日2016-06-01
最終更新日2017-02-01
実験手法ELECTRON MICROSCOPY (3.08 Å)
主引用文献Diverse roles of assembly factors revealed by structures of late nuclear pre-60S ribosomes
Nature, 534, 2016
3JZO
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HUMAN MDMX LIGANDED WITH A 12MER PEPTIDE (PDI)
分子名称:Protein Mdm4, pDI peptide (12mer), POTASSIUM ION
著者Schonbrunn, E., Phan, J.
登録日2009-09-23
公開日2009-11-10
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure-based design of high affinity peptides inhibiting the interaction of p53 with MDM2 and MDMX.
J.Biol.Chem., 285, 2010
3JZP
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HUMAN MDMX LIGANDED WITH A 12MER PEPTIDE INHIBITOR (PDI6W)
分子名称:Protein Mdm4, pDI6W peptide (12mer), POTASSIUM ION
著者Schonbrunn, E., Phan, J.
登録日2009-09-24
公開日2009-11-10
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献Structure-based design of high affinity peptides inhibiting the interaction of p53 with MDM2 and MDMX.
J.Biol.Chem., 285, 2010
3JZQ
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HUMAN MDMX LIGANDED WITH A 12MER PEPTIDE INHIBITOR (PDIQ)
分子名称:Protein Mdm4, pDIQ peptide (12mer), SULFATE ION
著者Schonbrunn, E., Phan, J.
登録日2009-09-24
公開日2009-11-10
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure-based design of high affinity peptides inhibiting the interaction of p53 with MDM2 and MDMX.
J.Biol.Chem., 285, 2010
3JZR
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HUMAN MDM2 LIGANDED WITH A 12MER PEPTIDE INHIBITOR (PDI6W)
分子名称:E3 ubiquitin-protein ligase Mdm2, pDI6W peptide (12mer)
著者Schonbrunn, E., Phan, J.
登録日2009-09-24
公開日2009-11-10
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure-based design of high affinity peptides inhibiting the interaction of p53 with MDM2 and MDMX.
J.Biol.Chem., 285, 2010
3JZS
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HUMAN MDM2 LIGANDED WITH A 12MER PEPTIDE INHIBITOR (PDIQ)
分子名称:E3 ubiquitin-protein ligase Mdm2, pDIQ peptide (12mer), 1,2-ETHANEDIOL
著者Schonbrunn, E., Phan, J.
登録日2009-09-24
公開日2009-11-10
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Structure-based design of high affinity peptides inhibiting the interaction of p53 with MDM2 and MDMX.
J.Biol.Chem., 285, 2010
3OW8
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CRYSTAL STRUCTURE OF THE WD REPEAT-CONTAINING PROTEIN 61
分子名称:WD repeat-containing protein 61, UNKNOWN ATOM OR ION
著者Tempel, W., Li, Z., Chao, X., Lam, R., Wernimont, A.K., He, H., Seitova, A., Pan, P.W., Li, Y., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Min, J., Structural Genomics Consortium (SGC)
登録日2010-09-17
公開日2010-09-29
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure and function of WD40 domain proteins.
Protein Cell, 2, 2011
3P71
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CRYSTAL STRUCTURE OF THE COMPLEX OF LCMT-1 AND PP2A
分子名称:Leucine carboxyl methyltransferase 1, Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform, DI(HYDROXYETHYL)ETHER, ...
著者Xing, Y., Stanevich, V., Satyshur, K.A., Jiang, L.
登録日2010-10-11
公開日2011-02-16
最終更新日2014-10-15
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The Structural Basis for Tight Control of PP2A Methylation and Function by LCMT-1.
Mol.Cell, 41, 2011
3RWL
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STRUCTURE OF P450PYR HYDROXYLASE
分子名称:Cytochrome P450 alkane hydroxylase 1 CYP153A7, PROTOPORPHYRIN IX CONTAINING FE
著者Pompidor, G.
登録日2011-05-09
公開日2012-04-18
最終更新日2012-04-25
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Evolving P450pyr hydroxylase for highly enantioselective hydroxylation at non-activated carbon atom.
Chem.Commun.(Camb.), 48, 2012
4HJW
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CRYSTAL STRUCTURE OF METARHIZIUM ANISOPLIAE IDCASE IN APO FORM
分子名称:Uracil-5-carboxylate decarboxylase, ZINC ION
著者Xu, S., Zhu, J., Ding, J.
登録日2012-10-14
公開日2013-09-11
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structures of isoorotate decarboxylases reveal a novel catalytic mechanism of 5-carboxyl-uracil decarboxylation and shed light on the search for DNA decarboxylase.
Cell Res., 23, 2013
4HK5
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CRYSTAL STRUCTURE OF CORDYCEPS MILITARIS IDCASE IN APO FORM
分子名称:Uracil-5-carboxylate decarboxylase, ZINC ION
著者Xu, S., Zhu, J., Ding, J.
登録日2012-10-15
公開日2013-09-11
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structures of isoorotate decarboxylases reveal a novel catalytic mechanism of 5-carboxyl-uracil decarboxylation and shed light on the search for DNA decarboxylase.
Cell Res., 23, 2013
4HK6
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CRYSTAL STRUCTURE OF CORDYCEPS MILITARIS IDCASE IN COMPLEX WITH 5-NITRO-URACIL
分子名称:Uracil-5-carboxylate decarboxylase, ZINC ION, 5-nitrouracil
著者Xu, S., Zhu, J., Ding, J.
登録日2012-10-15
公開日2013-09-11
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structures of isoorotate decarboxylases reveal a novel catalytic mechanism of 5-carboxyl-uracil decarboxylation and shed light on the search for DNA decarboxylase.
Cell Res., 23, 2013
4HK7
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CRYSTAL STRUCTURE OF CORDYCEPS MILITARIS IDCASE IN COMPLEX WITH URACIL
分子名称:Uracil-5-carboxylate decarboxylase, ZINC ION, URACIL
著者Xu, S., Zhu, J., Ding, J.
登録日2012-10-15
公開日2013-09-11
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.189 Å)
主引用文献Crystal structures of isoorotate decarboxylases reveal a novel catalytic mechanism of 5-carboxyl-uracil decarboxylation and shed light on the search for DNA decarboxylase.
Cell Res., 23, 2013