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4GK6
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X-RAY CRYSTAL STRUCTURE OF A HYPOTHETICAL DEOXYURIDINE 5-TRIPHOSPHATE NUCLEOTIDOHYDROLASE FROM MYCOBACTERIUM ABSCESSUS
Descriptor:Deoxyuridine 5'-triphosphate nucleotidohydrolase, CHLORIDE ION
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2012-08-10
Release date:2012-12-19
Last modified:2015-04-22
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95, 2015
4H3Y
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CRYSTAL STRUCTURE OF AN ASYMMETRIC DIMER OF A TRNA (GUANINE-(N(1)-)-METHYLTRANSFERASE FROM BURKHOLDERIA PHYMATUM BOUND TO S-ADENOSYL HOMOCYSTEIN IN ONE HALF-SITE
Descriptor:tRNA (guanine-N(1)-)-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, CHLORIDE ION
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2012-09-14
Release date:2012-10-03
Last modified:2013-10-30
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Combining functional and structural genomics to sample the essential Burkholderia structome.
Plos One, 8, 2013
4H3Z
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CRYSTAL STRUCTURE OF A SYMMETRIC DIMER OF A TRNA (GUANINE-(N(1)-)-METHYLTRANSFERASE FROM BURKHOLDERIA PHYMATUM BOUND TO S-ADENOSYL HOMOCYSTEIN IN BOTH HALF-SITES
Descriptor:tRNA (guanine-N(1)-)-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, CHLORIDE ION
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2012-09-14
Release date:2012-10-03
Last modified:2013-10-30
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Combining functional and structural genomics to sample the essential Burkholderia structome.
Plos One, 8, 2013
4H4G
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CRYSTAL STRUCTURE OF (3R)-HYDROXYMYRISTOYL-[ACYL-CARRIER-PROTEIN] DEHYDRATASE FROM BURKHOLDERIA THAILANDENSIS E264
Descriptor:(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase
Authors:Craig, T.K., Edwards, T.E., Staker, B., Stewart, L., Lorimer, D., Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2012-09-17
Release date:2012-10-03
Last modified:2013-10-30
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Combining functional and structural genomics to sample the essential Burkholderia structome.
Plos One, 8, 2013
4HDT
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CRYSTAL STRUCTURE OF A CARNITINYL-COA DEHYDRATASE FROM MYCOBACTERIUM THERMORESISTIBILE
Descriptor:3-hydroxyisobutyryl-CoA hydrolase, ZINC ION, CHLORIDE ION, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2012-10-02
Release date:2012-10-10
Last modified:2015-04-15
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95, 2015
4HR3
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STRUCTURE OF A PUTATIVE ACYL-COA DEHYDROGENASE FROM MYCOBACTERIUM ABSCESSUS
Descriptor:Putative acyl-CoA dehydrogenase, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2012-10-26
Release date:2012-11-14
Last modified:2015-04-22
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95, 2015
4I1Y
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THE STRUCTURE OF CYSTEINE SYNTHASE FROM MYCOBACTERIUM ULCERANS AGY99
Descriptor:Cysteine synthase, CHLORIDE ION, SULFATE ION
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2012-11-21
Release date:2012-12-26
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95, 2015
4IJN
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CRYSTAL STRUCTURE OF AN ACETATE KINASE FROM MYCOBACTERIUM SMEGMATIS BOUND TO AMP AND SULFATE
Descriptor:Acetate kinase, SULFATE ION, ADENOSINE MONOPHOSPHATE, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2012-12-21
Release date:2013-01-16
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95, 2015
4IV6
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X-RAY CRYSTAL STRUCTURE OF AN ISOVALERYL-COA DEHYDROGENASE FROM MYCOBACTERIUM SMEGMATIS
Descriptor:Acyl-CoA dehydrogenase FadE3, DIHYDROFLAVINE-ADENINE DINUCLEOTIDE
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2013-01-22
Release date:2013-03-20
Last modified:2015-04-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95, 2015
4IZ9
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CRYSTAL STRUCTURE OF AN ACETATE KINASE FROM MYCOBACTERIUM AVIUM BOUND TO AN UNKNOWN ACID-APCPP CONJUGATE AND MANGANESE
Descriptor:Acetate kinase, MANGANESE (II) ION, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2013-01-29
Release date:2013-02-20
Last modified:2015-04-22
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95, 2015
4J5I
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CRYSTAL STRUCTURE OF AN ALPHA-KETOGLUTARATE-DEPENDENT TAURINE DIOXYGENASE FROM MYCOBACTERIUM SMEGMATIS
Descriptor:Alpha-ketoglutarate-dependent taurine dioxygenase, FE (III) ION, 1,2-ETHANEDIOL, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2013-02-08
Release date:2013-02-20
Last modified:2015-04-22
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95, 2015
4KAM
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X-RAY CRYSTAL STRUCTURE OF O-ACETYLHOMOSERINE SULFHYDRYLASE METC FROM MYCOBACTERIUM MARINUM ATCC BAA-535 / M
Descriptor:O-acetylhomoserine sulfhydrylase MetC, SULFATE ION
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2013-04-22
Release date:2013-05-01
Last modified:2015-04-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95, 2015
4LGV
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X-RAY CRYSTAL STRUCTURE OF GLUCOSE-6-PHOSPHATE 1-DEHYDROGENASE FROM MYCOBACTERIUM AVIUM
Descriptor:Glucose-6-phosphate 1-dehydrogenase, GLYCEROL, CHLORIDE ION, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2013-06-28
Release date:2013-07-24
Last modified:2015-04-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95, 2015
4O2D
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CRYSTAL STRUCTURE OF ASPARTYL-TRNA SYNTHETASE FROM MYCOBACTERIUM SMEGMATIS WITH BOUND ASPARTIC ACID
Descriptor:Aspartate--tRNA ligase, ASPARTIC ACID, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2013-12-17
Release date:2014-01-22
Last modified:2015-04-22
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95, 2015
4RGB
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CRYSTAL STRUCTURE OF A PUTATIVE CARVEOL DEHYDROGENASE FROM MYCOBACTERIUM AVIUM BOUND TO NAD
Descriptor:Carveol dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2014-09-29
Release date:2014-10-15
Last modified:2017-02-08
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Mycofactocin-associated mycobacterial dehydrogenases with non-exchangeable NAD cofactors.
Sci Rep, 7, 2017
3DMS
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1.65A CRYSTAL STRUCTURE OF ISOCITRATE DEHYDROGENASE FROM BURKHOLDERIA PSEUDOMALLEI
Descriptor:Isocitrate dehydrogenase [NADP]
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2008-07-01
Release date:2008-07-15
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structural basis of the substrate specificity of bifunctional isocitrate dehydrogenase kinase/phosphatase.
Biochemistry, 50, 2011
3EIY
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CRYSTAL STRUCTURE OF INORGANIC PYROPHOSPHATASE FROM BURKHOLDERIA PSEUDOMALLEI WITH BOUND PYROPHOSPHATE
Descriptor:Inorganic pyrophosphatase, POTASSIUM ION, SODIUM ION, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2008-09-17
Release date:2008-09-30
Last modified:2013-10-23
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The role of medical structural genomics in discovering new drugs for infectious diseases.
PLoS Comput Biol, 5, 2009
3EJ0
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CRYSTAL STRUCTURE OF INORGANIC PYROPHOSPHATASE FROM BURKHOLDERIA PSEUDOMALLEI WITH BOUND N-(PYRIDIN-3-YLMETHYL) ANILINE, H32 CRYSTAL FORM
Descriptor:Inorganic pyrophosphatase, N-(pyridin-3-ylmethyl)aniline
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2008-09-17
Release date:2008-09-30
Last modified:2013-10-23
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:The role of medical structural genomics in discovering new drugs for infectious diseases.
PLoS Comput Biol, 5, 2009
3F0D
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HIGH RESOLUTION CRYSTAL STRUCTURE OF 2C-METHYL-D-ERYTHRITOL 2,4-CYCLODIPHOSPHATASE SYNTHASE FROM BURKHOLDERIA PSEUDOMALLEI
Descriptor:2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, ZINC ION
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2008-10-24
Release date:2008-11-04
Last modified:2013-10-30
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Leveraging structure determination with fragment screening for infectious disease drug targets: MECP synthase from Burkholderia pseudomallei.
J Struct Funct Genomics, 12, 2011
3F0E
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CRYSTAL STRUCTURE OF 2C-METHYL-D-ERYTHRITOL 2,4-CYCLODIPHOSPHATE SYNTHASE FROM BURKHOLDERIA PSEUDOMALLEI
Descriptor:2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MAGNESIUM ION, ZINC ION
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2008-10-24
Release date:2008-11-04
Last modified:2013-10-30
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Leveraging structure determination with fragment screening for infectious disease drug targets: MECP synthase from Burkholderia pseudomallei.
J Struct Funct Genomics, 12, 2011
3F0G
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CO-CRYSTAL STRUCTURE OF 2C-METHYL-D-ERYTHRITOL 2,4-CYCLODIPHOSPHATE SYNTHASE WITH CMP
Descriptor:2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, ZINC ION, CYTIDINE-5'-MONOPHOSPHATE
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2008-10-24
Release date:2008-11-04
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:Leveraging structure determination with fragment screening for infectious disease drug targets: MECP synthase from Burkholderia pseudomallei.
J Struct Funct Genomics, 12, 2011
3GMT
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CRYSTAL STRUCTURE OF ADENYLATE KINASE FROM BURKHOLDERIA PSEUDOMALLEI
Descriptor:Adenylate kinase, SULFATE ION
Authors:Abendroth, J., Staker, B.L., Robinson, H., Buchko, G.W., Hewitt, S.N., Napuli, A.J., Van Voorhis, W., Stacy, R., Myler, P.J., Stewart, L., Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2009-03-15
Release date:2009-06-02
Last modified:2013-10-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural characterization of Burkholderia pseudomallei adenylate kinase (Adk): profound asymmetry in the crystal structure of the 'open' state.
Biochem.Biophys.Res.Commun., 394, 2010
3HGB
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CRYSTAL STRUCTURE OF GLYCINE CLEAVAGE SYSTEM PROTEIN H FROM MYCOBACTERIUM TUBERCULOSIS
Descriptor:Glycine cleavage system H protein
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2009-05-13
Release date:2009-05-26
Last modified:2015-04-22
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:X-ray structure determination of the glycine cleavage system protein H of Mycobacterium tuberculosis using an inverse Compton synchrotron X-ray source.
J.Struct.Funct.Genom., 11, 2010
3HZU
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CRYSTAL STRUCTURE OF PROBABLE THIOSULFATE SULFURTRANSFERASE SSEA (RHODANESE) FROM MYCOBACTERIUM TUBERCULOSIS
Descriptor:Thiosulfate sulfurtransferase sseA, GLYCEROL, SULFATE ION
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2009-06-24
Release date:2009-07-07
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Mycobacterium thermoresistibile as a source of thermostable orthologs of Mycobacterium tuberculosis proteins.
Protein Sci., 21, 2012
3IEQ
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CRYSTAL STRUCTURE OF 2C-METHYL-D-ERYTHRITOL 2,4-CYCLODIPHOSPHATE SYNTHASE FROM BURKHOLDERIA PSEUDOMALLEI WITH CYTIDINE
Descriptor:2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, CYTIDINE-5'-MONOPHOSPHATE, ZINC ION, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2009-07-23
Release date:2009-08-04
Last modified:2013-10-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Leveraging structure determination with fragment screening for infectious disease drug targets: MECP synthase from Burkholderia pseudomallei.
J Struct Funct Genomics, 12, 2011