Author results

2Y7J
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STRUCTURE OF HUMAN PHOSPHORYLASE KINASE, GAMMA 2
Descriptor:PHOSPHORYLASE B KINASE GAMMA CATALYTIC CHAIN, TESTIS/LIVER ISOFORM, N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide
Authors:Muniz, J.R.C., Shrestha, A., Savitsky, P., Wang, J., Rellos, P., Fedorov, O., Burgess-Brown, N., Brenner, B., Berridge, G., Elkins, J.M., Krojer, T., Vollmar, M., Che, K.H., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Weigelt, J., Bountra, C., Knapp, S.
Deposit date:2011-01-31
Release date:2011-02-09
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of Human Phosphorylase Kinase, Gamma 2
To be Published
2YBX
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CRYSTAL STRUCTURE OF HUMAN PHOSPHATIDYLINOSITOL-5-PHOSPHATE 4-KINASE TYPE-2 ALPHA
Descriptor:PHOSPHATIDYLINOSITOL-5-PHOSPHATE 4-KINASE TYPE-2 ALPHA, PHOSPHATE ION
Authors:Tresaugues, L., Moche, M., Arrowsmith, C.H., Berglund, H., Bountra, C., Collins, R., Edwards, A.M., Ekblad, T., Flodin, S., Graslund, S., Karlberg, T., Kotenyova, T., Kouznetsova, E., Nyman, T., Persson, C., Schuler, H., Siponen, M.I., Thorsell, A.G., Wahlberg, E., Weigelt, J., Nordlund, P.
Deposit date:2011-03-30
Release date:2012-01-25
Method:X-RAY DIFFRACTION (2.56 Å)
Cite:Crystal Structure of Human Phosphatidylinositol-5-Phosphate 4-Kinase Type-2 Alpha
To be Published
2YF0
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HUMAN MYOTUBULARIN RELATED PROTEIN 6 (MTMR6)
Descriptor:MYOTUBULARIN-RELATED PROTEIN 6, SULFATE ION
Authors:Moche, M., Tresaugues, L., Arrowsmith, C.H., Berglund, H., Bountra, C., Collins, R., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Johansson, I., Karlberg, T., Kotenyova, T., Kouznetsova, E., Nyman, T., Persson, C., Schuler, H., Schutz, P., Siponen, M.I., Thorsell, A.G., VanDenBerg, S., Wahlberg, E., Weigelt, J., Welin, M., Nordlund, P.
Deposit date:2011-03-31
Release date:2011-04-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Crystal Structure of Human Mtmr6
To be Published
2YL2
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CRYSTAL STRUCTURE OF HUMAN ACETYL-COA CARBOXYLASE 1, BIOTIN CARBOXYLASE (BC) DOMAIN
Descriptor:ACETYL-COA CARBOXYLASE 1
Authors:Muniz, J.R.C., Froese, D.S., Krysztofinska, E., Vollmar, M., Beltrami, A., Krojer, T., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Weigelt, J., Bountra, C., Yue, W.W., Oppermann, U.
Deposit date:2011-05-31
Release date:2011-06-15
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Structure of Human Acetyl-Coa Carboxylase 1, Biotin Carboxylase (Bc) Domain
To be Published
2YPS
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CRYSTAL STRUCTURE OF THE PX DOMAIN OF HUMAN SORTING NEXIN 3
Descriptor:SORTING NEXIN-3
Authors:Canning, P., Kiyani, W., Froese, D.S., Krojer, T., Strain-Damerell, C., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Yue, W.W.
Deposit date:2012-10-31
Release date:2013-03-20
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal Structure of the Px Domain of Human Sorting Nexin 3
To be Published
3B4U
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CRYSTAL STRUCTURE OF DIHYDRODIPICOLINATE SYNTHASE FROM AGROBACTERIUM TUMEFACIENS STR. C58
Descriptor:Dihydrodipicolinate synthase, MAGNESIUM ION
Authors:Zhang, R., Xu, L., Gu, J., Savchenko, A., Edwards, A.M., Joachimiak, A., Midwest Center for Structural Genomics (MCSG)
Deposit date:2007-10-24
Release date:2007-12-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:The crystal structure of the dihydrodipicolinate synthase from Agrobacterium tumefaciens.
To be Published
3B6E
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CRYSTAL STRUCTURE OF HUMAN DECH-BOX RNA HELICASE MDA5 (MELANOMA DIFFERENTIATION-ASSOCIATED PROTEIN 5), DECH-DOMAIN
Descriptor:Interferon-induced helicase C domain-containing protein 1, SODIUM ION
Authors:Karlberg, T., Welin, M., Arrowsmith, C.H., Berglund, H., Busam, R.D., Collins, R., Dahlgren, L.G., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Johansson, I., Kallas, A., Kotenyova, T., Lehtio, L., Moche, M., Nilsson, M.E., Nordlund, P., Nyman, T., Persson, C., Sagemark, J., Svensson, L., Thorsell, A.G., Tresaugues, L., Van Den Berg, S., Weigelt, J., Holmberg-Schiavone, L., Structural Genomics Consortium (SGC)
Deposit date:2007-10-29
Release date:2007-11-13
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Human DECH-box RNA Helicase MDA5 (Melanoma differentiation-associated protein 5), DECH-domain.
To be Published
3B6N
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CRYSTAL STRUCTURE OF 2C-METHYL-D-ERYTHRITOL 2,4-CYCLODIPHOSPHATE SYNTHASE PV003920 FROM PLASMODIUM VIVAX
Descriptor:2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, ZINC ION
Authors:Wernimont, A.K., Lew, J., Kozieradzki, I., Lin, Y.H., Sun, X., Khuu, C., Zhao, Y., Schapira, M., Arrowsmith, C.H., Edwards, A.M., Weigelt, J., Bochkarev, A., Hui, R., Artz, J.D., Xiao, T., Structural Genomics Consortium (SGC)
Deposit date:2007-10-29
Release date:2007-11-20
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Crystal structure of 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase PV003920 from Plasmodium vivax.
To be Published
3B6U
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CRYSTAL STRUCTURE OF THE MOTOR DOMAIN OF HUMAN KINESIN FAMILY MEMBER 3B IN COMPLEX WITH ADP
Descriptor:Kinesin-like protein KIF3B, MAGNESIUM ION, ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Zhu, H., Shen, Y., Tempel, W., Landry, R., Arrowsmith, C.H., Edwards, A.M., Sundstrom, M., Weigelt, J., Bochkarev, A., Park, H., Structural Genomics Consortium (SGC)
Deposit date:2007-10-29
Release date:2007-11-13
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Motor domain of human kinesin family member 3B in complex with ADP.
To be Published
3B6V
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CRYSTAL STRUCTURE OF THE MOTOR DOMAIN OF HUMAN KINESIN FAMILY MEMBER 3C IN COMPLEX WITH ADP
Descriptor:Kinesin-like protein KIF3C, MAGNESIUM ION, ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Zhu, H., Tempel, W., Shen, Y., Landry, R., Arrowsmith, C.H., Edwards, A.M., Sundstrom, M., Weigelt, J., Bochkarev, A., Park, H., Structural Genomics Consortium (SGC)
Deposit date:2007-10-29
Release date:2007-11-13
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Motor domain of human kinesin family member 3C in complex with ADP.
To be Published
3B76
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CRYSTAL STRUCTURE OF THE THIRD PDZ DOMAIN OF HUMAN LIGAND-OF-NUMB PROTEIN-X (LNX1) IN COMPLEX WITH THE C-TERMINAL PEPTIDE FROM THE COXSACKIEVIRUS AND ADENOVIRUS RECEPTOR
Descriptor:E3 ubiquitin-protein ligase LNX, SODIUM ION, 1,2-ETHANEDIOL
Authors:Ugochukwu, E., Burgess-Brown, N., Berridge, G., Elkins, J., Bunkoczi, G., Pike, A.C.W., Sundstrom, M., Arrowsmith, C.H., Weigelt, J., Edwards, A.M., Gileadi, O., von Delft, F., Doyle, D., Structural Genomics Consortium (SGC)
Deposit date:2007-10-30
Release date:2007-11-13
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal structure of the third PDZ domain of human ligand-of-numb protein-X (LNX1) in complex with the C-terminal peptide from the coxsackievirus and adenovirus receptor.
To be Published
3B7K
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HUMAN ACYL-COENZYME A THIOESTERASE 12
Descriptor:Acyl-coenzyme A thioesterase 12, COENZYME A
Authors:Lehtio, L., Busam, R.D., Arrowsmith, C.H., Collins, R., Dahlgren, L.G., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Hallberg, B.M., Herman, M.D., Johansson, A., Johansson, I., Kallas, A., Karlberg, T., Kotenyova, T., Moche, M., Nilsson, M.E., Nordlund, P., Nyman, T., Persson, C., Sagemark, J., Sundstrom, M., Svensson, L., Thorsell, A.G., Tresaugues, L., Van Den Berg, S., Weigelt, J., Welin, M., Berglund, H., Structural Genomics Consortium (SGC)
Deposit date:2007-10-31
Release date:2007-11-13
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Human Acyl-coenzyme A thioesterase 12.
To be Published
3B7L
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HUMAN FARNESYL DIPHOSPHATE SYNTHASE COMPLEXED WITH MG AND MINODRONATE
Descriptor:Farnesyl pyrophosphate synthetase, MAGNESIUM ION, (1-HYDROXY-2-IMIDAZO[1,2-A]PYRIDIN-3-YLETHANE-1,1-DIYL)BIS(PHOSPHONIC ACID)
Authors:Pilka, E.S., Dunford, J.E., Guo, K., Pike, A.C.W., Kavanagh, K.L., von Delft, F., Ebetino, F.H., Arrowsmith, C.H., Edwards, A.M., Russell, R.G.G., Oppermann, U., Structural Genomics Consortium (SGC)
Deposit date:2007-10-31
Release date:2007-11-13
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Human farnesyl diphosphate synthase complexed with MG and minodronate.
TO BE PUBLISHED
3B7P
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CRYSTAL STRUCTURE OF SPERMIDINE SYNTHASE FROM PLASMODIUM FALCIPARUM IN COMPLEX WITH SPERMINE
Descriptor:Spermidine synthase, SPERMINE, 5'-DEOXY-5'-METHYLTHIOADENOSINE
Authors:Qiu, W., Dong, A., Ren, H., Wu, H., Zhao, Y., Schapira, M., Wasney, G., Vedadi, M., Lew, J., Kozieradzki, I., Edwards, A.M., Arrowsmith, C.H., Weigelt, J., Sundstrom, M., Plotnikov, A.N., Bochkarev, A., Hui, R., Structural Genomics Consortium (SGC)
Deposit date:2007-10-31
Release date:2007-11-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of spermidine synthase from Plasmodium falciparum in complex with spermine.
To be Published
3B7X
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CRYSTAL STRUCTURE OF HUMAN FK506-BINDING PROTEIN 6
Descriptor:FK506-binding protein 6
Authors:Walker, J.R., Davis, T., Butler-Cole, C., Paramanathan, R., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Dhe-Paganon, S., Structural Genomics Consortium (SGC)
Deposit date:2007-10-31
Release date:2007-11-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Human FK506-Binding Protein 6.
To be Published
3B7Y
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CRYSTAL STRUCTURE OF THE C2 DOMAIN OF THE E3 UBIQUITIN-PROTEIN LIGASE NEDD4
Descriptor:E3 ubiquitin-protein ligase NEDD4, CALCIUM ION
Authors:Walker, J.R., Ruzanov, M., Butler-Cole, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Dhe-Paganon, S., Structural Genomics Consortium (SGC)
Deposit date:2007-10-31
Release date:2007-11-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:C2 Domain of the Human E3 Ubiquitin-Protein Ligase NEDD4.
To be Published
3B84
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CRYSTAL STRUCTURE OF THE HUMAN BTB DOMAIN OF THE KRUEPPEL RELATED ZINC FINGER PROTEIN 3 (HKR3)
Descriptor:Zinc finger and BTB domain-containing protein 48, UNKNOWN, 1,2-ETHANEDIOL
Authors:Filippakopoulos, P., Bullock, A., Cooper, C., Keates, T., Salah, E., Pilka, E., Pike, A.C.W., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Weigelt, J., Knapp, S., Structural Genomics Consortium (SGC)
Deposit date:2007-10-31
Release date:2007-11-20
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Crystal Structure of the Human BTB domain of the Krueppel related Zinc Finger Protein 3 (HKR3).
To be Published
3BE4
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CRYSTAL STRUCTURE OF CRYPTOSPORIDIUM PARVUM ADENYLATE KINASE CGD5_3360
Descriptor:Adenylate kinase, MAGNESIUM ION, BIS(ADENOSINE)-5'-PENTAPHOSPHATE, ...
Authors:Wernimont, A.K., Lew, J., Kozieradzki, I., Lin, Y.H., Sun, X., Khuu, C., Zhao, Y., Schapira, M., Arrowsmith, C.H., Edwards, A.M., Weigelt, J., Bochkarev, A., Hui, R., Artz, J.D., Amani, M., Structural Genomics Consortium (SGC)
Deposit date:2007-11-16
Release date:2007-12-18
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structure of Cryptosporidium parvum adenylate kinase cgd5_3360.
To be Published
3BFK
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CRYSTAL STRUCTURE OF PLASMODIUM FALCIPARUM RAB11A IN COMPLEX WITH GDP
Descriptor:Small GTPase Rab11, GUANOSINE-5'-DIPHOSPHATE, GLYCEROL
Authors:Pizarro, J.C., Sukumar, D., Hassanali, A., Lin, L., Wernimont, A.K., Lew, J., Kozieradzki, I., Edwards, A.M., Arrowsmith, C.H., Weigelt, J., Sundstrom, M., Bochkarev, A., Hui, R., Structural Genomics Consortium (SGC)
Deposit date:2007-11-21
Release date:2007-12-04
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of Plasmodium falciparum Rab11a in complex with GDP.
To be Published
3BFO
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CRYSTAL STRUCTURE OF IG-LIKE C2-TYPE 2 DOMAIN OF THE HUMAN MUCOSA-ASSOCIATED LYMPHOID TISSUE LYMPHOMA TRANSLOCATION PROTEIN 1
Descriptor:Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Isoform 2)
Authors:Walker, J.R., Akutsu, M., Littler, D.R., Li, Y., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Dhe-Paganon, S., Structural Genomics Consortium (SGC)
Deposit date:2007-11-22
Release date:2007-12-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:Structure of the Ig-like C2-type 2 domain of the human Mucosa-associated lymphoid tissue lymphoma translocation protein 1.
To be Published
3BGV
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CRYSTAL STRUCTURE OF MRNA CAP GUANINE-N7 METHYLTRANSFERASE IN COMPLEX WITH SAH
Descriptor:mRNA cap guanine-N7 methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Lunin, V.V., Wu, H., Zeng, H., Antoshenko, T., MacKenzie, F., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Min, J., Plotnikov, A.N., Structural Genomics Consortium (SGC)
Deposit date:2007-11-27
Release date:2007-12-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The crystal structure of human RNA (guanine-7-) methyltransferase in complex with SAH.
To be Published
3BHD
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CRYSTAL STRUCTURE OF HUMAN THIAMINE TRIPHOSPHATASE (THTPA)
Descriptor:Thiamine triphosphatase, SULFATE ION, CHLORIDE ION, ...
Authors:Busam, R.D., Lehtio, L., Arrowsmith, C.H., Collins, R., Dahlgren, L.G., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Hallberg, B.M., Herman, M.D., Johansson, A., Johansson, I., Kallas, A., Karlberg, T., Kotenyova, T., Moche, M., Nilsson, M.E., Nordlund, P., Nyman, T., Persson, C., Sagemark, J., Sundstrom, M., Svensson, L., Thorsell, A.G., Tresaugues, L., Van den Berg, S., Weigelt, J., Welin, M., Berglund, H., Structural Genomics Consortium (SGC)
Deposit date:2007-11-28
Release date:2007-12-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal Structure of Human Thiamine Triphosphatase.
To be Published
3BHH
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CRYSTAL STRUCTURE OF HUMAN CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE IIB ISOFORM 1 (CAMK2B)
Descriptor:Calcium/calmodulin-dependent protein kinase type II beta chain, [4-({4-[(5-cyclopropyl-1H-pyrazol-3-yl)amino]-6-(methylamino)pyrimidin-2-yl}amino)phenyl]acetonitrile
Authors:Filippakopoulos, P., Rellos, P., Niesen, F., Burgess, N., Bullock, A., Berridge, G., Pike, A.C.W., Ugochukwu, E., Pilka, E.S., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Weigelt, J., Knapp, S., Structural Genomics Consortium (SGC)
Deposit date:2007-11-28
Release date:2007-12-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Structure of Human Calcium/Calmodulin-Dependent Protein Kinase IIB Isoform 1 (CAMK2B).
To be Published
3BIG
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CRYSTAL STRUCTURE OF THE FRUCTOSE-1,6-BISPHOSPHATASE GLPX FROM E.COLI IN COMPLEX WITH INORGANIC PHOSPHATE
Descriptor:Fructose-1,6-bisphosphatase class II glpX, PHOSPHATE ION, UNKNOWN ATOM OR ION
Authors:Lunin, V.V., Skarina, T., Brown, G., Yakunin, A.F., Edwards, A.M., Savchenko, A.
Deposit date:2007-11-30
Release date:2008-12-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural and Biochemical Characterization of the Type II Fructose-1,6-bisphosphatase GlpX from Escherichia coli.
J.Biol.Chem., 284, 2009
3BIH
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CRYSTAL STRUCTURE OF FRUCTOSE-1,6-BISPHOSPHATASE FROM E.COLI GLPX
Descriptor:Fructose-1,6-bisphosphatase class II glpX, UNKNOWN ATOM OR ION
Authors:Lunin, V.V., Skarina, T., Brown, G., Yakunin, A.F., Edwards, A.M., Savchenko, A.
Deposit date:2007-11-30
Release date:2008-12-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural and Biochemical Characterization of the Type II Fructose-1,6-bisphosphatase GlpX from Escherichia coli.
J.Biol.Chem., 284, 2009