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5TS4
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CRYSTAL STRUCTURE OF A DE NOVO DESIGNED PROTEIN WITH CURVED BETA-SHEET
Descriptor:denovo NTF2, DI(HYDROXYETHYL)ETHER
Authors:Basanta, B., Oberdorfer, G., Chidyausiku, T.M., Marcos, E., Pereira, J.H., Sankaran, B., Zwart, P.H., Baker, D.
Deposit date:2016-10-27
Release date:2017-01-25
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (3.005 Å)
Cite:Principles for designing proteins with cavities formed by curved beta sheets.
Science, 355, 2017
5TX8
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SOLUTION STRUCTURE OF THE DE NOVO MINI PROTEIN GHH_44
Descriptor:HH2
Authors:Buchko, G.W., Bahl, C.D., Baker, D.
Deposit date:2016-11-15
Release date:2017-09-27
Last modified:2018-10-31
Method:SOLUTION NMR
Cite:Cytosolic expression, solution structures, and molecular dynamics simulation of genetically encodable disulfide-rich de novo designed peptides.
Protein Sci., 27, 2018
5U35
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CRYSTAL STRUCTURE OF A DE NOVO DESIGNED PROTEIN WITH CURVED BETA-SHEET
Descriptor:De novo NTF2 with large cavity, 2-METHOXYETHANOL, CHLORIDE ION, ...
Authors:Oberdorfer, G., Marcos, E., Basanta, B., Chidyausiku, T.M., Sankaran, B., Zwart, P.H., Baker, D.
Deposit date:2016-12-01
Release date:2017-01-25
Last modified:2017-02-01
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Principles for designing proteins with cavities formed by curved beta sheets.
Science, 355, 2017
5UOI
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SOLUTION STRUCTURE OF THE DE NOVO MINI PROTEIN HHH_RD1_0142
Descriptor:HHH_rd1_0142
Authors:Houliston, S., Rocklin, G.J., Lemak, A., Carter, L., Chidyausiku, T.M., Baker, D., Arrowsmith, C.H.
Deposit date:2017-01-31
Release date:2017-07-26
Method:SOLUTION NMR
Cite:Global analysis of protein folding using massively parallel design, synthesis, and testing.
Science, 357, 2017
5UP1
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SOLUTION STRUCTURE OF THE DE NOVO MINI PROTEIN EEHEE_RD3_1049
Descriptor:EEHEE_rd3_1049
Authors:Houliston, S., Rocklin, G.J., Lemak, A., Carter, L., Chidyausiku, T.M., Baker, D., Arrowsmith, C.H.
Deposit date:2017-02-01
Release date:2017-07-26
Method:SOLUTION NMR
Cite:Global analysis of protein folding using massively parallel design, synthesis, and testing.
Science, 357, 2017
5UP5
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SOLUTION STRUCTURE OF THE DE NOVO MINI PROTEIN EHEE_RD1_0284
Descriptor:EHEE_rd1_0284
Authors:Houliston, S., Rocklin, G.J., Lemak, A., Carter, L., Chidyausiku, T.M., Baker, D., Arrowsmith, C.H.
Deposit date:2017-02-01
Release date:2017-07-26
Method:SOLUTION NMR
Cite:Global analysis of protein folding using massively parallel design, synthesis, and testing.
Science, 357, 2017
5UYO
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SOLUTION NMR STRUCTURE OF THE DE NOVO MINI PROTEIN HEEH_RD4_0097
Descriptor:HEEH_rd4_0097
Authors:Lemak, A., Rocklin, G.J., Houliston, S., Carter, L., Chidyausiku, T.M., Baker, D., Arrowsmith, C.H.
Deposit date:2017-02-24
Release date:2017-07-26
Last modified:2018-11-07
Method:SOLUTION NMR
Cite:Global analysis of protein folding using massively parallel design, synthesis, and testing.
Science, 357, 2017
5W9F
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SOLUTION STRUCTURE OF THE DE NOVO MINI PROTEIN GHEEE_02
Descriptor:De novo mini protein gHEEE_02
Authors:Pulavarti, S.V.S.R.K., Shaw, E.A., Bahl, C.D., Garry, B.W., Baker, D., Szyperski, T.
Deposit date:2017-06-23
Release date:2018-07-11
Last modified:2018-10-31
Method:SOLUTION NMR
Cite:Cytosolic expression, solution structures, and molecular dynamics simulation of genetically encodable disulfide-rich de novo designed peptides.
Protein Sci., 27, 2018
6BE7
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SOLUTION STRUCTURE OF DE NOVO MACROCYCLE DESIGN8.1
Descriptor:DDPT(DPR)(DAR)Q(DGN)
Authors:Shortridge, M.D., Hosseinzadeh, P., Pardo-Avila, F., Varani, G., Baker, D.
Deposit date:2017-10-24
Release date:2018-01-03
Last modified:2018-01-17
Method:SOLUTION NMR
Cite:Comprehensive computational design of ordered peptide macrocycles.
Science, 358, 2017
6BEO
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SOLUTION STRUCTURE OF DE NOVO MACROCYCLE DESIGN9.1
Descriptor:(DPR)PY(DHI)PKDL(DGN)
Authors:Shortridge, M.D., Hosseinzadeh, P., Pardo-Avila, F., Varani, G., Baker, D.
Deposit date:2017-10-25
Release date:2017-12-27
Method:SOLUTION NMR
Cite:Comprehensive computational design of ordered peptide macrocycles.
Science, 358, 2017
6BEQ
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SOLUTION STRUCTURE OF DE NOVO MACROCYCLE DESIGN10.1
Descriptor:AAR(DVA)(DPR)R(DLE)(DTH)PE
Authors:Shortridge, M.D., Hosseinzadeh, P., Pardo-Avila, F., Varani, G., Baker, D.
Deposit date:2017-10-25
Release date:2018-01-10
Method:SOLUTION NMR
Cite:Comprehensive computational design of ordered peptide macrocycles.
Science, 358, 2017
6BER
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SOLUTION STRUCTURE OF DE NOVO MACROCYCLE DESIGN10.2
Descriptor:E(DVA)DP(DGL)(DHI)(DPR)N(DAL)(DPR)
Authors:Shortridge, M.D., Hosseinzadeh, P., Pardo-Avila, F., Varani, G., Baker, D.
Deposit date:2017-10-25
Release date:2017-12-27
Method:SOLUTION NMR
Cite:Comprehensive computational design of ordered peptide macrocycles.
Science, 358, 2017
6BES
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SOLUTION STRUCTURE OF DE NOVO MACROCYCLE DESIGN11_SS
Descriptor:(DAL)Q(DPR)(DCY)(DLY)DS(DTY)(DCY)P(DSN)
Authors:Shortridge, M.D., Hosseinzadeh, P., Pardo-Avila, F., Varani, G., Baker, D.
Deposit date:2017-10-25
Release date:2017-12-27
Method:SOLUTION NMR
Cite:Comprehensive computational design of ordered peptide macrocycles.
Science, 358, 2017
6BET
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SOLUTION STRUCTURE OF DE NOVO MACROCYCLE DESIGN12_SS
Descriptor:H(DPR)(DVA)CIP(DPR)E(DLY)VC(DGL)
Authors:Shortridge, M.D., Hosseinzadeh, P., Pardo-Avila, F., Varani, G., Baker, D.
Deposit date:2017-10-25
Release date:2017-12-27
Method:SOLUTION NMR
Cite:Comprehensive computational design of ordered peptide macrocycles.
Science, 358, 2017
6BEU
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SOLUTION STRUCTURE OF DE NOVO MACROCYCLE DESIGN14_SS
Descriptor:(DCY)N(DVA)(DPR)DVYC(DPR)(DSG)KY(DVA)(DPR)
Authors:Shortridge, M.D., Hosseinzadeh, P., Pardo-Avila, F., Varani, G., Baker, D.
Deposit date:2017-10-25
Release date:2017-12-27
Method:SOLUTION NMR
Cite:Comprehensive computational design of ordered peptide macrocycles.
Science, 358, 2017
6BEW
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SOLUTION STRUCTURE OF DE NOVO MACROCYCLE DESIGN7.2
Descriptor:(DHI)P(DAS)(DGN)(DSN)(DGL)P
Authors:Shortridge, M.D., Hosseinzadeh, P., Pardo-Avila, F., Varani, G., Baker, D.
Deposit date:2017-10-25
Release date:2017-12-27
Method:SOLUTION NMR
Cite:Comprehensive computational design of ordered peptide macrocycles.
Science, 358, 2017
6BF3
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SOLUTION STRUCTURE OF DE NOVO MACROCYCLE DESIGN7.3A
Descriptor:QDP(DPR)K(2TL)(DAS)
Authors:Shortridge, M.D., Hosseinzadeh, P., Pardo-Avila, F., Varani, G., Baker, D.
Deposit date:2017-10-25
Release date:2018-01-10
Method:SOLUTION NMR
Cite:Comprehensive computational design of ordered peptide macrocycles.
Science, 358, 2017
6BF5
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SOLUTION STRUCTURE OF DE NOVO MACROCYCLE DESIGN7.3A
Descriptor:QDP(DPR)K(DTH)(DAS)
Authors:Shortridge, M.D., Hosseinzadeh, P., Pardo-Avila, F., Varani, G., Baker, D.
Deposit date:2017-10-25
Release date:2018-01-10
Method:SOLUTION NMR
Cite:Comprehensive computational design of ordered peptide macrocycles.
Science, 358, 2017
6D0T
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DE NOVO DESIGN OF A FLUORESCENCE-ACTIVATING BETA BARREL - BB1
Descriptor:BB1
Authors:Dou, J., Vorobieva, A.A., Sheffler, W., Doyle, L.A., Park, H., Bick, M.J., Mao, B., Foight, G.W., Lee, M., Carter, L., Sankaran, B., Ovchinnikov, S., Marcos, E., Huang, P., Vaughan, J.C., Stoddard, B.L., Baker, D.
Deposit date:2018-04-10
Release date:2018-09-19
Last modified:2018-10-17
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:De novo design of a fluorescence-activating beta-barrel.
Nature, 561, 2018
6DG5
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STRUCTURE OF A DE NOVO DESIGNED INTERLEUKIN-2/INTERLEUKIN-15 MIMETIC COMPLEX WITH IL-2RB AND IL-2RG
Descriptor:Neoleukin-2/15, Interleukin-2 receptor subunit beta, Cytokine receptor common subunit gamma, ...
Authors:Jude, K.M., Silva, D.-A., Yu, S., Baker, D., Garcia, K.C.
Deposit date:2018-05-16
Release date:2019-01-16
Last modified:2019-01-23
Method:X-RAY DIFFRACTION (2.516 Å)
Cite:De novo design of potent and selective mimics of IL-2 and IL-15.
Nature, 565, 2019
6DG6
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STRUCTURE OF A DE NOVO DESIGNED INTERLEUKIN-2/INTERLEUKIN-15 MIMETIC
Descriptor:Neoleukin-2/15
Authors:Jude, K.M., Silva, D.-A., Yu, S., Baker, D., Garcia, K.C.
Deposit date:2018-05-16
Release date:2019-01-16
Last modified:2019-01-23
Method:X-RAY DIFFRACTION (1.999 Å)
Cite:De novo design of potent and selective mimics of IL-2 and IL-15.
Nature, 565, 2019
6E5C
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SOLUTION NMR STRUCTURE OF A DE NOVO DESIGNED DOUBLE-STRANDED BETA-HELIX
Descriptor:De novo beta protein
Authors:Marcos, E., Chidyausiku, T.M., McShan, A., Evangelidis, T., Nerli, S., Sgourakis, N., Tripsianes, K., Baker, D.
Deposit date:2018-07-19
Release date:2018-11-07
Last modified:2018-11-14
Method:SOLUTION NMR
Cite:De novo design of a non-local beta-sheet protein with high stability and accuracy.
Nat. Struct. Mol. Biol., 25, 2018
6E9R
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DHF46 FILAMENT
Descriptor:DHF46 filament
Authors:Lynch, E.M., Shen, H., Fallas, J.A., Kollman, J.M., Baker, D.
Deposit date:2018-08-01
Release date:2018-11-21
Method:ELECTRON MICROSCOPY (5.9 Å)
Cite:De novo design of self-assembling helical protein filaments.
Science, 362, 2018
6E9T
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DHF58 FILAMENT
Descriptor:DHF58 filament
Authors:Lynch, E.M., Shen, H., Fallas, J.A., Kollman, J.M., Baker, D.
Deposit date:2018-08-01
Release date:2018-11-21
Method:ELECTRON MICROSCOPY (5.4 Å)
Cite:De novo design of self-assembling helical protein filaments.
Science, 362, 2018
6E9V
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DHF79 FILAMENT
Descriptor:DHF79 filament
Authors:Lynch, E.M., Shen, H., Fallas, J.A., Kollman, J.M., Baker, D.
Deposit date:2018-08-01
Release date:2018-11-21
Method:ELECTRON MICROSCOPY (6.9 Å)
Cite:De novo design of self-assembling helical protein filaments.
Science, 362, 2018