Author results

6C9H
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NON-PHOSPHORYLATED AMP-ACTIVATED PROTEIN KINASE BOUND TO PHARMACOLOGICAL ACTIVATOR R734
Descriptor:5'-AMP-activated protein kinase catalytic subunit alpha-1, 5'-AMP-activated protein kinase subunit beta-1, 5'-AMP-activated protein kinase subunit gamma-1, ...
Authors:Yan, Y., Zhou, X.E., Novick, S., Shaw, S.J., Li, Y., Hitoshi, Y., Brunzelle, J.S., Griffin, P.R., Xu, H.E., Melcher, K.
Deposit date:2018-01-26
Release date:2018-11-28
Last modified:2019-01-30
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structures of AMP-activated protein kinase bound to novel pharmacological activators in phosphorylated, non-phosphorylated, and nucleotide-free states.
J. Biol. Chem., 294, 2019
6C9J
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AMP-ACTIVATED PROTEIN KINASE BOUND TO PHARMACOLOGICAL ACTIVATOR R734
Descriptor:5'-AMP-activated protein kinase catalytic subunit alpha-1, 5'-AMP-activated protein kinase subunit beta-1, 5'-AMP-activated protein kinase subunit gamma-1, ...
Authors:Yan, Y., Zhou, X.E., Novick, S., Shaw, S.J., Li, Y., Brunzelle, J.S., Hitoshi, Y., Griffin, P.R., Xu, H.E., Melcher, K.
Deposit date:2018-01-26
Release date:2018-11-28
Last modified:2019-01-30
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Structures of AMP-activated protein kinase bound to novel pharmacological activators in phosphorylated, non-phosphorylated, and nucleotide-free states.
J. Biol. Chem., 294, 2019
1APH
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CONFORMATIONAL CHANGES IN CUBIC INSULIN CRYSTALS IN THE PH RANGE 7-11
Descriptor:INSULIN A CHAIN (PH 7), INSULIN B CHAIN (PH 7), 1,2-DICHLOROETHANE
Authors:Gursky, O., Badger, J., Li, Y., Caspar, D.L.D.
Deposit date:1992-10-30
Release date:1993-01-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Conformational changes in cubic insulin crystals in the pH range 7-11.
Biophys.J., 63, 1992
1BPH
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CONFORMATIONAL CHANGES IN CUBIC INSULIN CRYSTALS IN THE PH RANGE 7-11
Descriptor:INSULIN A CHAIN (PH 9), INSULIN B CHAIN (PH 9), SODIUM ION, ...
Authors:Gursky, O., Badger, J., Li, Y., Caspar, D.L.D.
Deposit date:1992-10-30
Release date:1993-01-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Conformational changes in cubic insulin crystals in the pH range 7-11.
Biophys.J., 63, 1992
1C6V
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SIV INTEGRASE (CATALYTIC DOMAIN + DNA BIDING DOMAIN COMPRISING RESIDUES 50-293) MUTANT WITH PHE 185 REPLACED BY HIS (F185H)
Descriptor:PROTEIN (SIV INTEGRASE), PROTEIN (SIU89134)
Authors:Chen, Z., Yan, Y., Munshi, S., Li, Y., Zruygay-Murphy, J., Xu, B., Witmer, M., Felock, P., Wolfe, A., Sardana, V., Emini, E.A., Hazuda, D., Kuo, L.C.
Deposit date:1999-12-21
Release date:2000-12-27
Last modified:2018-03-14
Method:X-RAY DIFFRACTION (3 Å)
Cite:X-ray structure of simian immunodeficiency virus integrase containing the core and C-terminal domain (residues 50-293)--an initial glance of the viral DNA binding platform.
J.Mol.Biol., 296, 2000
1CPH
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CONFORMATIONAL CHANGES IN CUBIC INSULIN CRYSTALS IN THE PH RANGE 7-11
Descriptor:INSULIN (PH 10), SODIUM ION, 1,2-DICHLOROETHANE
Authors:Gursky, O., Badger, J., Li, Y., Caspar, D.L.D.
Deposit date:1992-10-30
Release date:1993-01-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Conformational changes in cubic insulin crystals in the pH range 7-11.
Biophys.J., 63, 1992
1DPH
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CONFORMATIONAL CHANGES IN CUBIC INSULIN CRYSTALS IN THE PH RANGE 7-11
Descriptor:INSULIN A CHAIN (PH 11), INSULIN B CHAIN (PH 11), SODIUM ION, ...
Authors:Gursky, O., Badger, J., Li, Y., Caspar, D.L.D.
Deposit date:1992-10-30
Release date:1993-01-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Conformational changes in cubic insulin crystals in the pH range 7-11.
Biophys.J., 63, 1992
1EOJ
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DESIGN OF P1' AND P3' RESIDUES OF TRIVALENT THROMBIN INHIBITORS AND THEIR CRYSTAL STRUCTURES
Descriptor:ALPHA THROMBIN, THROMBIN INHIBITOR P798
Authors:Slon-Usakiewicz, J.J., Sivaraman, J., Li, Y., Cygler, M., Konishi, Y.
Deposit date:2000-03-23
Release date:2000-05-03
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Design of P1' and P3' residues of trivalent thrombin inhibitors and their crystal structures.
Biochemistry, 39, 2000
1EOL
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DESIGN OF P1' AND P3' RESIDUES OF TRIVALENT THROMBIN INHIBITORS AND THEIR CRYSTAL STRUCTURES
Descriptor:ALPHA THROMBIN, THROMBIN INHIBITOR P628
Authors:Slon-Usakiewicz, J.J., Sivaraman, J., Li, Y., Cygler, M., Konishi, Y.
Deposit date:2000-03-23
Release date:2000-05-03
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Design of P1' and P3' residues of trivalent thrombin inhibitors and their crystal structures.
Biochemistry, 39, 2000
1EPT
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REFINED 1.8 ANGSTROMS RESOLUTION CRYSTAL STRUCTURE OF PORCINE EPSILON-TRYPSIN
Descriptor:PORCINE E-TRYPSIN, CALCIUM ION
Authors:Huang, Q., Wang, Z., Li, Y., Liu, S., Tang, Y.
Deposit date:1994-06-07
Release date:1995-02-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Refined 1.8 A resolution crystal structure of the porcine epsilon-trypsin.
Biochim.Biophys.Acta, 1209, 1994
1F2E
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STRUCTURE OF SPHINGOMONAD, GLUTATHIONE S-TRANSFERASE COMPLEXED WITH GLUTATHIONE
Descriptor:GLUTATHIONE S-TRANSFERASE, GLUTATHIONE
Authors:Nishio, T., Watanabe, T., Patel, A., Wang, Y., Lau, P.C.K., Grochulski, P., Li, Y., Cygler, M.
Deposit date:2000-05-24
Release date:2000-06-21
Last modified:2011-12-21
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Properties of a Sphingomonad and Marine Bacterium Beta-Class Glutathione S-Transferases and Crystal Structure of the Former Complex with Glutathione
To be published
1KXG
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THE 2.0 ANG RESOLUTION STRUCTURE OF BLYS, B LYMPHOCYTE STIMULATOR.
Descriptor:B lymphocyte stimulator, MAGNESIUM ION, CITRIC ACID, ...
Authors:Oren, D.A., Li, Y., Volovik, Y., Morris, T.S., Dharia, C., Das, K., Galperina, O., Gentz, R., Arnold, E.
Deposit date:2002-01-31
Release date:2002-03-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis of BLyS receptor recognition.
Nat.Struct.Biol., 9, 2002
1Q57
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THE CRYSTAL STRUCTURE OF THE BIFUNCTIONAL PRIMASE-HELICASE OF BACTERIOPHAGE T7
Descriptor:DNA primase/helicase
Authors:Toth, E.A., Li, Y., Sawaya, M.R., Cheng, Y., Ellenberger, T.
Deposit date:2003-08-06
Release date:2003-11-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.45 Å)
Cite:The Crystal Structure of the Bifunctional Primase-Helicase of Bacteriophage T7
Mol.Cell, 12, 2003
1T0F
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CRYSTAL STRUCTURE OF THE TNSA/TNSC(504-555) COMPLEX
Descriptor:Transposon Tn7 transposition protein tnsA, Transposon Tn7 transposition protein tnsC, MAGNESIUM ION, ...
Authors:Ronning, D.R., Li, Y., Perez, Z.N., Ross, P.D., Hickman, A.B., Craig, N.L., Dyda, F.
Deposit date:2004-04-08
Release date:2004-11-09
Last modified:2017-12-20
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:The carboxy-terminal portion of TnsC activates the Tn7 transposase through a specific interaction with TnsA.
Embo J., 23, 2004
2AYD
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CRYSTAL STRUCTURE OF THE C-TERMINAL WRKY DOMAINOF ATWRKY1, AN SA-INDUCED AND PARTIALLY NPR1-DEPENDENT TRANSCRIPTION FACTOR
Descriptor:WRKY transcription factor 1, ZINC ION, SUCCINIC ACID
Authors:Duan, M.R., Nan, J., Li, Y., Su, X.D.
Deposit date:2005-09-07
Release date:2006-10-31
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:DNA binding mechanism revealed by high resolution crystal structure of Arabidopsis thaliana WRKY1 protein.
Nucleic Acids Res., 35, 2007
2FMX
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AN OPEN CONFORMATION OF SWITCH I REVEALED BY SAR1-GDP CRYSTAL STRUCTURE AT LOW MG(2+)
Descriptor:GTP-binding protein SAR1b, SULFATE ION, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Rao, Y., Bian, C., Yuan, C., Li, Y., Huang, M.
Deposit date:2006-01-10
Release date:2006-09-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:An open conformation of switch I revealed by Sar1-GDP crystal structure at low Mg(2+)
Biochem.Biophys.Res.Commun., 348, 2006
2G1J
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CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS SHIKIMATE KINASE AT 2.0 ANGSTROM RESOLUTION
Descriptor:Shikimate kinase, SULFATE ION
Authors:Gan, J., Gu, Y., Li, Y., Yan, H., Ji, X.
Deposit date:2006-02-14
Release date:2006-07-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of Mycobacterium tuberculosis Shikimate Kinase in Complex with Shikimic Acid and an ATP Analogue.
Biochemistry, 45, 2006
2G1K
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CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS SHIKIMATE KINASE IN COMPLEX WITH SHIKIMATE AT 1.75 ANGSTROM RESOLUTION
Descriptor:Shikimate kinase, SULFATE ION, CHLORIDE ION, ...
Authors:Gan, J., Gu, Y., Li, Y., Yan, H., Ji, X.
Deposit date:2006-02-14
Release date:2006-07-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal Structure of Mycobacterium tuberculosis Shikimate Kinase in Complex with Shikimic Acid and an ATP Analogue.
Biochemistry, 45, 2006
2HK7
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CRYSTAL STRUCTURE OF SHIKIMATE DEHYDROGENASE FROM AQUIFEX AEOLICUS IN COMPLEX WITH MERCURY AT 2.5 ANGSTROM RESOLUTION
Descriptor:Shikimate dehydrogenase, MERCURY (II) ION
Authors:Gan, J.H., Prabakaran, P., Gu, Y.J., Andrykovitch, M., Li, Y., Liu, H.H., Yan, H., Ji, X.
Deposit date:2006-07-03
Release date:2007-06-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural and biochemical analyses of shikimate dehydrogenase AroE from Aquifex aeolicus: implications for the catalytic mechanism.
Biochemistry, 46, 2007
2HK8
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CRYSTAL STRUCTURE OF SHIKIMATE DEHYDROGENASE FROM AQUIFEX AEOLICUS AT 2.35 ANGSTROM RESOLUTION
Descriptor:Shikimate dehydrogenase
Authors:Gan, J.H., Prabakaran, P., Gu, Y.J., Andrykovitch, M., Li, Y., Liu, H.H., Yan, H., Ji, X.
Deposit date:2006-07-03
Release date:2007-06-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural and biochemical analyses of shikimate dehydrogenase AroE from Aquifex aeolicus: implications for the catalytic mechanism.
Biochemistry, 46, 2007
2HK9
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CRYSTAL STRUCTURE OF SHIKIMATE DEHYDROGENASE FROM AQUIFEX AEOLICUS IN COMPLEX WITH SHIKIMATE AND NADP+ AT 2.2 ANGSTROM RESOLUTION
Descriptor:Shikimate dehydrogenase, 2'-MONOPHOSPHOADENOSINE-5'-DIPHOSPHATE, (3R,4S,5R)-3,4,5-TRIHYDROXYCYCLOHEX-1-ENE-1-CARBOXYLIC ACID, ...
Authors:Gan, J.H., Prabakaran, P., Gu, Y.J., Andrykovitch, M., Li, Y., Liu, H.H., Yan, H., Ji, X.
Deposit date:2006-07-03
Release date:2007-06-19
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural and biochemical analyses of shikimate dehydrogenase AroE from Aquifex aeolicus: implications for the catalytic mechanism.
Biochemistry, 46, 2007
2PW6
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CRYSTAL STRUCTURE OF UNCHARACTERIZED PROTEIN JW3007 FROM ESCHERICHIA COLI K12
Descriptor:Uncharacterized protein ygiD, ZINC ION
Authors:Newton, M.G., Takagi, Y., Ebihara, A., Shinkai, A., Kuramitsu, S., Yokayama, S., Li, Y., Chen, L., Zhu, J., Ruble, J., Liu, Z.J., Rose, J.P., Wang, B.-C., Southeast Collaboratory for Structural Genomics (SECSG), RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-05-10
Release date:2007-06-12
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Crystal structure of uncharacterized protein JW3007 from Escherichia coli K12.
To be Published
3EBQ
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CRYSTAL STRUCTURE OF HUMAN PPPDE1
Descriptor:MOLECULE: PPPDE1 (PERMUTED PAPAIN FOLD PEPTIDASES OF DSRNA VIRUSES AND EUKARYOTES 1), UPF0326 protein FAM152B, MERCURY (II) ION
Authors:Walker, J.R., Akutsu, M., Qiu, L., Li, Y., Slessarev, Y., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Botchkarev, A., Dhe-Paganon, S., Structural Genomics Consortium (SGC)
Deposit date:2008-08-28
Release date:2008-11-04
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of Human PPPDE1
To be Published
3ECR
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STRUCTURE OF HUMAN PORPHOBILINOGEN DEAMINASE
Descriptor:Porphobilinogen deaminase, 3-[5-{[3-(2-carboxyethyl)-4-(carboxymethyl)-5-methyl-1H-pyrrol-2-yl]methyl}-4-(carboxymethyl)-1H-pyrrol-3-yl]propanoic acid
Authors:Song, G., Li, Y., Cheng, C., Zhao, Y., Gao, A., Zhang, R., Joachimiak, A., Shaw, N., Liu, Z.J.
Deposit date:2008-09-01
Release date:2008-09-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.182 Å)
Cite:Structural insight into acute intermittent porphyria.
Faseb J., 23, 2009
3G5K
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STRUCTURE AND ACTIVITY OF HUMAN MITOCHONDRIAL PEPTIDE DEFORMYLASE, A NOVEL CANCER TARGET
Descriptor:Peptide deformylase, mitochondrial, ACTINONIN, ...
Authors:Escobar-Alvarez, S., Goldgur, Y., Yang, G., Ouerfelli, O., Li, Y., Scheinberg, D.A.
Deposit date:2009-02-05
Release date:2009-04-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure and activity of human mitochondrial peptide deformylase, a novel cancer target
J.Mol.Biol., 387, 2009