Author results

4N0F
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HUMAN FCRN COMPLEXED WITH HUMAN SERUM ALBUMIN
分子名称:IgG receptor FcRn large subunit p51, Beta-2-microglobulin, Serum albumin
著者Oganesyan, V., Wu, H., Dall'Acqua, W.F.
登録日2013-10-01
公開日2014-02-05
最終更新日2014-04-09
実験手法X-RAY DIFFRACTION (3.02 Å)
主引用文献Structural Insights into Neonatal Fc Receptor-based Recycling Mechanisms.
J.Biol.Chem., 289, 2014
4N0U
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TERNARY COMPLEX BETWEEN NEONATAL FC RECEPTOR, SERUM ALBUMIN AND FC
分子名称:IgG receptor FcRn large subunit p51, Beta-2-microglobulin, Serum albumin, ...
著者Oganesyan, V., Wu, H., Dall'Acqua, W.F.
登録日2013-10-02
公開日2014-02-05
最終更新日2014-04-02
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Structural Insights into Neonatal Fc Receptor-based Recycling Mechanisms.
J.Biol.Chem., 289, 2014
4NFW
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STRUCTURE AND ATYPICAL HYDROLYSIS MECHANISM OF THE NUDIX HYDROLASE ORF153 (YMFB) FROM ESCHERICHIA COLI
分子名称:Putative Nudix hydrolase ymfB, MANGANESE (II) ION, SULFATE ION
著者Hong, M.K., Kim, J.K., Kang, L.W.
登録日2013-11-01
公開日2014-05-14
最終更新日2015-03-11
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Divalent metal ion-based catalytic mechanism of the Nudix hydrolase Orf153 (YmfB) from Escherichia coli
Acta Crystallogr.,Sect.D, 70, 2014
4NFX
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STRUCTURE AND ATYPICAL HYDROLYSIS MECHANISM OF THE NUDIX HYDROLASE ORF153 (YMFB) FROM ESCHERICHIA COLI
分子名称:Putative Nudix hydrolase ymfB
著者Hong, M.K., Kim, J.K., Kang, L.W.
登録日2013-11-01
公開日2014-05-14
最終更新日2015-03-11
実験手法X-RAY DIFFRACTION (2.69 Å)
主引用文献Divalent metal ion-based catalytic mechanism of the Nudix hydrolase Orf153 (YmfB) from Escherichia coli
Acta Crystallogr.,Sect.D, 70, 2014
4NSP
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CRYSTAL STRUCTURE OF HUMAN ENDOV
分子名称:Endonuclease V
著者Xie, W., Zhang, Z., Hao, Z.
登録日2013-11-28
公開日2014-09-10
最終更新日2014-09-24
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of human endonuclease V as an inosine-specific ribonuclease.
Acta Crystallogr.,Sect.D, 70, 2014
4RSC
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CRYSTAL STRUCTURE OF RPE65 IN COMPLEX WITH EMIXUSTAT AND PALMITATE
分子名称:Retinoid isomerohydrolase, FE (II) ION, PALMITIC ACID, ...
著者Kiser, P.D., Shi, W., Palczewski, K.
登録日2014-11-07
公開日2015-04-15
最終更新日2015-06-03
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Catalytic mechanism of a retinoid isomerase essential for vertebrate vision.
Nat.Chem.Biol., 11, 2015
4RSE
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CRYSTAL STRUCTURE OF RPE65 IN COMPLEX WITH MB-001 AND PALMITATE
分子名称:Retinoid isomerohydrolase, FE (II) ION, PALMITIC ACID, ...
著者Kiser, P.D., Shi, W., Palczewski, K.
登録日2014-11-07
公開日2015-04-15
最終更新日2015-06-03
実験手法X-RAY DIFFRACTION (2.39 Å)
主引用文献Catalytic mechanism of a retinoid isomerase essential for vertebrate vision.
Nat.Chem.Biol., 11, 2015
4U3A
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CRYSTAL STRUCTURE OF CTCEL5E
分子名称:Endoglucanase H
著者Yuan, S.F., Liang, P.H., Ho, M.C.
登録日2014-07-19
公開日2015-01-14
最終更新日2017-10-04
実験手法X-RAY DIFFRACTION (2.42 Å)
主引用文献Biochemical Characterization and Structural Analysis of a Bifunctional Cellulase/Xylanase from Clostridium thermocellum
J.Biol.Chem., 290, 2015
4U5I
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COMPLEX STRUCTURE OF MUTANT CTCEL5E (E314A) WITH XYLOBIOSE
分子名称:Endoglucanase H, 4-O-beta-D-xylopyranosyl-beta-D-xylopyranose
著者Guo, R.T., Huang, C.H., Wu, T.H.
登録日2014-07-25
公開日2015-01-14
最終更新日2015-03-11
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Biochemical Characterization and Structural Analysis of a Bifunctional Cellulase/Xylanase from Clostridium thermocellum
J.Biol.Chem., 290, 2015
4U5K
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COMPLEX STRUCTURE OF MUTANT CTCEL5E (E314A) WITH CELLOBIOSE
分子名称:Endoglucanase H, CELLOBIOSE
著者Guo, R.T., Huang, C.H., Wu, T.H.
登録日2014-07-25
公開日2015-01-14
最終更新日2015-03-11
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Biochemical Characterization and Structural Analysis of a Bifunctional Cellulase/Xylanase from Clostridium thermocellum
J.Biol.Chem., 290, 2015
4UXL
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STRUCTURE OF HUMAN ROS1 KINASE DOMAIN IN COMPLEX WITH PF-06463922
分子名称:PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ROS, (10R)-7-amino-12-fluoro-2,10,16-trimethyl-15-oxo-10,15,16,17-tetrahydro-2H-8,4-(metheno)pyrazolo[4,3-h][2,5,11]benzoxadiazacyclotetradecine-3-carbonitrile
著者McTigue, M., Deng, Y., Liu, W., Brooun, A., Stewart, A.
登録日2014-08-25
公開日2015-03-11
最終更新日2019-05-08
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Pf-06463922 is a Potent and Selective Next-Generation Ros1/Alk Inhibitor Capable of Blocking Crizotinib-Resistant Ros1 Mutations.
Proc.Natl.Acad.Sci.USA, 112, 2015
5GLX
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CRYSTAL STRUCTURE OF A GLYCOSIDE HYDROLASE FROM THIELAVIA TERRESTRIS NRRL 8126
分子名称:Glycoside hydrolase family 45 protein
著者Gao, J., Liu, W.D., Zheng, Y.Y., Chen, C.C., Guo, R.T.
登録日2016-07-12
公開日2017-04-19
実験手法X-RAY DIFFRACTION (1.42 Å)
主引用文献Characterization and crystal structure of a thermostable glycoside hydrolase family 45 1,4-beta-endoglucanase from Thielavia terrestris
Enzyme Microb. Technol., 99, 2017
5GLY
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CRYSTAL STRUCTURE OF A GLYCOSIDE HYDROLASE IN COMPLEX WITH CELLOTETROSE FROM THIELAVIA TERRESTRIS NRRL 8126
分子名称:Glycoside hydrolase family 45 protein, beta-D-glucopyranosyl-(1->4)-beta-D-glucopyranosyl-(1->4)-beta-D-glucopyranosyl-(1->4)-beta-D-glucopyranose, CELLOTRIOSE
著者Gao, J., Liu, W.D., Zheng, Y.Y., Chen, C.C., Guo, R.T.
登録日2016-07-12
公開日2017-04-19
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献Characterization and crystal structure of a thermostable glycoside hydrolase family 45 1,4-beta-endoglucanase from Thielavia terrestris
Enzyme Microb. Technol., 99, 2017
5GM3
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CRYSTAL STRUCTURE OF FI-CMCASE FROM ASPERGILLUS ACULEATUS F-50
分子名称:Endoglucanase-1, ZINC ION, CACODYLATE ION
著者Huang, J.W., Liu, W.D., Zheng, Y.Y., Chen, C.C., Guo, R.T.
登録日2016-07-12
公開日2017-05-17
実験手法X-RAY DIFFRACTION (1.59 Å)
主引用文献Crystal structure and genetic modifications of FI-CMCase from Aspergillus aculeatus F-50
Biochem. Biophys. Res. Commun., 478, 2016
5GM4
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CRYSTAL STRUCTURE OF FI-CMCASE FROM ASPERGILLUS ACULEATUS F-50 IN COMPLEX WITH CELLOTETROSE
分子名称:Endoglucanase-1, SULFATE ION, beta-D-glucopyranosyl-(1->4)-beta-D-glucopyranosyl-(1->4)-beta-D-glucopyranosyl-(1->4)-beta-D-glucopyranose
著者Huang, J.W., Liu, W.D., Zheng, Y.Y., Chen, C.C., Guo, R.T.
登録日2016-07-12
公開日2017-05-17
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Crystal structure and genetic modifications of FI-CMCase from Aspergillus aculeatus F-50
Biochem. Biophys. Res. Commun., 478, 2016
5GM5
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CRYSTAL STRUCTURE OF FI-CMCASE FROM ASPERGILLUS ACULEATUS F-50 IN COMPLEX WITH CELLOBIOSE
分子名称:Endoglucanase-1, CELLOBIOSE, SULFATE ION, ...
著者Huang, J.W., Liu, W.D., Zheng, Y.Y., Chen, C.C., Guo, R.T.
登録日2016-07-12
公開日2017-05-17
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献Crystal structure and genetic modifications of FI-CMCase from Aspergillus aculeatus F-50
Biochem. Biophys. Res. Commun., 478, 2016
5GM9
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CRYSTAL STRUCTURE OF A GLYCOSIDE HYDROLASE IN COMPLEX WITH CELLOBIOSE
分子名称:Glycoside hydrolase family 45 protein, 4-O-beta-D-glucopyranosyl-alpha-D-glucopyranose, CELLOBIOSE
著者Gao, J., Liu, W.D., Zheng, Y.Y., Chen, C.C., Guo, R.T.
登録日2016-07-13
公開日2017-04-19
実験手法X-RAY DIFFRACTION (1.36 Å)
主引用文献Characterization and crystal structure of a thermostable glycoside hydrolase family 45 1,4-beta-endoglucanase from Thielavia terrestris
Enzyme Microb. Technol., 99, 2017
5H31
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STRUCTURAL BASIS FOR DIMERIZATION OF THE DEATH EFFECTOR DOMAINS OF CASPASE-8
分子名称:Caspase-8
著者Shen, C., Pei, J., Guo, X., Quan, J.
登録日2016-10-19
公開日2017-10-25
実験手法X-RAY DIFFRACTION (3.169535 Å)
主引用文献Structural basis for dimerization of the death effector domains of Caspase-8
To Be Published
5H33
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STRUCTURAL BASIS FOR DIMERIZATION OF THE DEATH EFFECTOR DOMAINS OF CASPASE-8
分子名称:Caspase-8
著者Shen, C., Pei, J., Guo, X., Quan, J.
登録日2016-10-20
公開日2017-10-25
実験手法X-RAY DIFFRACTION (3.600138 Å)
主引用文献Structural basis for dimerization of the death effector domains of Caspase-8
To Be Published
5TWL
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STRUCTURE OF MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE
分子名称:Maternal embryonic leucine zipper kinase, 9-(3,5-dichloro-4-hydroxyphenyl)-1-{trans-4-[(dimethylamino)methyl]cyclohexyl}-3,4-dihydropyrimido[5,4-c]quinolin-2(1H)-one
著者Seo, H.-S., Huang, H.-T., Gray, N.S., Dhe-Paganon, S.
登録日2016-11-14
公開日2017-11-22
最終更新日2018-12-19
実験手法X-RAY DIFFRACTION (2.42 Å)
主引用文献MELK is not necessary for the proliferation of basal-like breast cancer cells.
Elife, 6, 2017
5TWY
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STRUCTURE OF MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE
分子名称:Maternal embryonic leucine zipper kinase, 2-(benzyloxy)-4-(1H-pyrazol-4-yl)-N-(2,3,4,5-tetrahydro-1H-3-benzazepin-7-yl)benzamide
著者Seo, H.-S., Dhe-Paganon, S.
登録日2016-11-15
公開日2017-11-22
最終更新日2019-06-05
実験手法X-RAY DIFFRACTION (2.91 Å)
主引用文献MELK is not necessary for the proliferation of basal-like breast cancer cells.
Elife, 6, 2017
5TWZ
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STRUCTURE OF MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE
分子名称:Maternal embryonic leucine zipper kinase, 7-{[2-methoxy-4-(1H-pyrazol-4-yl)benzoyl]amino}-2,3,4,5-tetrahydro-1H-3-benzazepinium
著者Seo, H.-Y., Dhe-Paganon, S.
登録日2016-11-15
公開日2017-11-22
最終更新日2019-06-05
実験手法X-RAY DIFFRACTION (2.631 Å)
主引用文献MELK is not necessary for the proliferation of basal-like breast cancer cells.
Elife, 6, 2017
5UUT
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N-MYRISTOYLTRANSFERASE 1 (NMT) BOUND TO MYRISTOYL-COA
分子名称:Glycylpeptide N-tetradecanoyltransferase 1, TETRADECANOYL-COA, CITRIC ACID
著者Goodwin, O., Pegan, S.
登録日2017-02-17
公開日2018-01-17
最終更新日2019-01-30
実験手法X-RAY DIFFRACTION (2.252 Å)
主引用文献Blocking Myristoylation of Src Inhibits Its Kinase Activity and Suppresses Prostate Cancer Progression.
Cancer Res., 77, 2017
6EG9
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IRAK4 IN COMPLEX WITH PONATINIB
分子名称:Interleukin-1 receptor-associated kinase 4, 3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzamide, SULFATE ION, ...
著者Wang, L., Wu, H.
登録日2018-08-19
公開日2019-02-20
最終更新日2019-09-04
実験手法X-RAY DIFFRACTION (2.414 Å)
主引用文献Conformational flexibility and inhibitor binding to unphosphorylated interleukin-1 receptor-associated kinase 4 (IRAK4).
J.Biol.Chem., 294, 2019
6EGA
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IRAK4 IN COMPLEX WITH A TYPE II INHIBITOR
分子名称:Interleukin-1 receptor-associated kinase 4, 3-{2-[(cyclopropanecarbonyl)amino][1,3]thiazolo[5,4-b]pyridin-5-yl}-N-{4-[(piperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzamide, SULFATE ION, ...
著者Wang, L., Wu, H.
登録日2018-08-19
公開日2019-02-20
最終更新日2019-09-04
実験手法X-RAY DIFFRACTION (2.512 Å)
主引用文献Conformational flexibility and inhibitor binding to unphosphorylated interleukin-1 receptor-associated kinase 4 (IRAK4).
J.Biol.Chem., 294, 2019