1OMY
 
 | | Crystal Structure of a Recombinant alpha-insect Toxin BmKaIT1 from the scorpion Buthus martensii Karsch | | Descriptor: | ACETIC ACID, Alpha-neurotoxin TX12, CHLORIDE ION | | Authors: | Huang, Y, Huang, Q, Chen, H, Tang, Y, Miyake, H, Kusunoki, M. | | Deposit date: | 2003-02-26 | | Release date: | 2003-09-09 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystallization and preliminary crystallographic study of rBmKalphaIT1, a recombinant alpha-insect toxin from the scorpion Buthus martensii Karsch.
Acta Crystallogr.,Sect.D, 59, 2003
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1D2G
 | | CRYSTAL STRUCTURE OF R175K MUTANT GLYCINE N-METHYLTRANSFERASE FROM RAT LIVER | | Descriptor: | GLYCINE N-METHYLTRANSFERASE | | Authors: | Huang, Y, Komoto, J, Takusagawa, F, Konishi, K, Takata, Y. | | Deposit date: | 1999-10-08 | | Release date: | 1999-10-25 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Mechanisms for auto-inhibition and forced product release in glycine N-methyltransferase: crystal structures of wild-type, mutant R175K and S-adenosylhomocysteine-bound R175K enzymes.
J.Mol.Biol., 298, 2000
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1D2H
 | | CRYSTAL STRUCTURE OF R175K MUTANT GLYCINE N-METHYLTRANSFERASE COMPLEXED WITH S-ADENOSYLHOMOCYSTEINE | | Descriptor: | GLYCINE N-METHYLTRANSFERASE, S-ADENOSYL-L-HOMOCYSTEINE | | Authors: | Huang, Y, Komoto, J, Takusagawa, F, Konishi, K, Takata, Y. | | Deposit date: | 1999-10-11 | | Release date: | 1999-10-25 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Mechanisms for auto-inhibition and forced product release in glycine N-methyltransferase: crystal structures of wild-type, mutant R175K and S-adenosylhomocysteine-bound R175K enzymes.
J.Mol.Biol., 298, 2000
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1D2C
 | | METHYLTRANSFERASE | | Descriptor: | PROTEIN (GLYCINE N-METHYLTRANSFERASE) | | Authors: | Huang, Y, Takusagawa, F. | | Deposit date: | 1999-09-23 | | Release date: | 1999-10-06 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Mechanisms for auto-inhibition and forced product release in glycine N-methyltransferase: crystal structures of wild-type, mutant R175K and S-adenosylhomocysteine-bound R175K enzymes.
J.Mol.Biol., 298, 2000
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3HTX
 | | Crystal structure of small RNA methyltransferase HEN1 | | Descriptor: | 5'-R(*GP*AP*UP*UP*UP*CP*UP*CP*UP*CP*UP*GP*CP*AP*AP*GP*CP*GP*AP*AP*AP*G)-3', 5'-R(P*UP*UP*CP*GP*CP*UP*UP*GP*CP*AP*GP*AP*GP*AP*GP*AP*AP*AP*UP*CP*AP*C)-3', HEN1, ... | | Authors: | Huang, Y, Ji, L.-J, Huang, Q.-C, Vassylyev, D.G, Chen, X.-M, Ma, J.-B. | | Deposit date: | 2009-06-12 | | Release date: | 2009-09-29 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Structural insights into mechanisms of the small RNA methyltransferase HEN1.
Nature, 461, 2009
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1I4O
 | | CRYSTAL STRUCTURE OF THE XIAP/CASPASE-7 COMPLEX | | Descriptor: | BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 4, CASPASE-7 | | Authors: | Huang, Y, Park, Y.C, Rich, R.L, Segal, D, Myszka, D.G, Wu, H. | | Deposit date: | 2001-02-22 | | Release date: | 2001-03-21 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structural basis of caspase inhibition by XIAP: differential roles of the linker versus the BIR domain.
Cell(Cambridge,Mass.), 104, 2001
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1PW4
 | | Crystal Structure of the Glycerol-3-Phosphate Transporter from E.Coli | | Descriptor: | Glycerol-3-phosphate transporter | | Authors: | Huang, Y, Lemieux, M.J, Song, J, Auer, M, Wang, D.N. | | Deposit date: | 2003-06-30 | | Release date: | 2003-08-05 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Structure and Mechanism of the Glycerol-3-Phosphate Transporter from Escherichia Coli
Science, 301, 2003
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8GTB
 | | Cryo-EM structure of the marine siphophage vB_DshS-R4C tail tube protein | | Descriptor: | Major tail protein | | Authors: | Huang, Y, Sun, H, Wei, S, Zheng, Q, Li, S, Zhang, R, Xia, N. | | Deposit date: | 2022-09-08 | | Release date: | 2023-07-12 | | Method: | ELECTRON MICROSCOPY (3.43 Å) | | Cite: | Structure and proposed DNA delivery mechanism of a marine roseophage.
Nat Commun, 14, 2023
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8GTD
 | | Cryo-EM model of the marine siphophage vB_DshS-R4C portal-adaptor complex | | Descriptor: | Head-to-tail joining protein, Portal protein | | Authors: | Huang, Y, Sun, H, Wei, S, Zheng, Q, Li, S, Zhang, R, Xia, N. | | Deposit date: | 2022-09-08 | | Release date: | 2023-07-12 | | Method: | ELECTRON MICROSCOPY (4.7 Å) | | Cite: | Structure and proposed DNA delivery mechanism of a marine roseophage.
Nat Commun, 14, 2023
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8GTC
 | | Cryo-EM model of the marine siphophage vB_DshS-R4C baseplate-tail complex | | Descriptor: | Distal tail protein, Hub protein, Major tail protein, ... | | Authors: | Huang, Y, Sun, H, Wei, S, Zheng, Q, Li, S, Zhang, R, Xia, N. | | Deposit date: | 2022-09-08 | | Release date: | 2023-07-12 | | Method: | ELECTRON MICROSCOPY (4.5 Å) | | Cite: | Structure and proposed DNA delivery mechanism of a marine roseophage.
Nat Commun, 14, 2023
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8GTF
 | | Cryo-EM model of the marine siphophage vB_DshS-R4C stopper-terminator complex | | Descriptor: | Head-to-tail joining protein, Major tail protein, Terminator protein | | Authors: | Huang, Y, Sun, H, Wei, S, Zheng, Q, Li, S, Zhang, R, Xia, N. | | Deposit date: | 2022-09-08 | | Release date: | 2023-07-12 | | Method: | ELECTRON MICROSCOPY (6.6 Å) | | Cite: | Structure and proposed DNA delivery mechanism of a marine roseophage.
Nat Commun, 14, 2023
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3MJ0
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3FIP
 | | Crystal structure of Usher PapC translocation pore | | Descriptor: | Outer membrane usher protein papC | | Authors: | Huang, Y, Deisenhofer, J. | | Deposit date: | 2008-12-12 | | Release date: | 2009-09-08 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (3.154 Å) | | Cite: | Insights into pilus assembly and secretion from the structure and functional characterization of usher PapC.
Proc.Natl.Acad.Sci.USA, 106, 2009
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2GF7
 | | Double tudor domain structure | | Descriptor: | Jumonji domain-containing protein 2A, SULFATE ION | | Authors: | Huang, Y, Fang, J, Bedford, M.T, Zhang, Y, Xu, R.M. | | Deposit date: | 2006-03-21 | | Release date: | 2006-05-02 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Recognition of histone H3 lysine-4 methylation by the double tudor domain of JMJD2A
Science, 312, 2006
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2GFA
 | | double tudor domain complex structure | | Descriptor: | Jumonji domain-containing protein 2A, peptide | | Authors: | Huang, Y, Fang, J, Bedford, M.T, Zhang, Y, Xu, R.M. | | Deposit date: | 2006-03-21 | | Release date: | 2006-05-02 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Recognition of histone H3 lysine-4 methylation by the double tudor domain of JMJD2A
Science, 312, 2006
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5WQA
 | | Crystal structure of PDE4D catalytic domain complexed with Selaginpulvilins K | | Descriptor: | 1-[2-(4-hydroxyphenyl)ethynyl]-9,9-bis(4-methoxyphenyl)-7-oxidanyl-fluorene-2-carbaldehyde, MAGNESIUM ION, ZINC ION, ... | | Authors: | Huang, Y, Zhang, T, Zheng, X, Yin, S, Luo, H.B. | | Deposit date: | 2016-11-24 | | Release date: | 2017-02-22 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | The discovery, complex crystal structure, and recognition mechanism of a novel natural PDE4 inhibitor from Selaginella pulvinata
Biochem. Pharmacol., 130, 2017
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7CFH
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7CFI
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7CFG
 | | Structure of the transmembrane domain of the bacterial CNNM/CorC family Mg2+ transporter in complex with Mg2+ | | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Hemolysin, MAGNESIUM ION, ... | | Authors: | Huang, Y, Jin, F, Hattori, M. | | Deposit date: | 2020-06-25 | | Release date: | 2021-02-24 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Structural basis for the Mg 2+ recognition and regulation of the CorC Mg 2+ transporter.
Sci Adv, 7, 2021
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7CFF
 | | Structure of the thermostabilized transmembrane domain of the bacterial CNNM/CorC family Mg2+ transporter in complex with Mg2+ | | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Hemolysin, ... | | Authors: | Huang, Y, Jin, F, Hattori, M. | | Deposit date: | 2020-06-25 | | Release date: | 2021-02-24 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural basis for the Mg 2+ recognition and regulation of the CorC Mg 2+ transporter.
Sci Adv, 7, 2021
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8HPI
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2FMM
 | | Crystal Structure of EMSY-HP1 complex | | Descriptor: | Chromobox protein homolog 1, Protein EMSY, SULFATE ION | | Authors: | Huang, Y. | | Deposit date: | 2006-01-09 | | Release date: | 2006-05-23 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Crystal structure of the HP1-EMSY complex reveals an unusual mode of HP1 binding.
Structure, 14, 2006
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7CFK
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7YL2
 | | Crystal Structure of the first bromodomain of human BRD4 in complex with the inhibitor Y07004 | | Descriptor: | Bromodomain-containing protein 4, GLYCEROL, N-(1-ethyl-2-oxidanylidene-3H-indol-5-yl)cyclohexanesulfonamide, ... | | Authors: | Huang, Y, Wei, A, Dong, R, Xu, H, Zhang, C, Chen, Z, Li, J, Wu, X, Zhang, Y, Xu, Y. | | Deposit date: | 2022-07-25 | | Release date: | 2023-07-26 | | Method: | X-RAY DIFFRACTION (1.62 Å) | | Cite: | Crystal Structure of the first bromodomain of human BRD4 in complex with the inhibitor Y07004
To Be Published
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2IJG
 | | Crystal Structure of cryptochrome 3 from Arabidopsis thaliana | | Descriptor: | 5,10-METHENYL-6,7,8-TRIHYDROFOLIC ACID, Cryptochrome DASH, chloroplast/mitochondrial, ... | | Authors: | Huang, Y, Deisenhofer, J. | | Deposit date: | 2006-09-29 | | Release date: | 2006-11-28 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Crystal structure of cryptochrome 3 from Arabidopsis thaliana and its implications for photolyase activity
Proc.Natl.Acad.Sci.Usa, 103, 2006
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