Author results

2JEP
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NATIVE FAMILY 5 XYLOGLUCANASE FROM PAENIBACILLUS PABULI
Descriptor:XYLOGLUCANASE, 1,2-ETHANEDIOL, CALCIUM ION
Authors:Gloster, T.M., Ibatullin, F.M., Macauley, K., Eklof, J.M., Roberts, S., Turkenburg, J.P., Bjornvad, M.E., Jorgensen, P.L., Danielsen, S., Johansen, K., Borchert, T.V., Wilson, K.S., Brumer, H., Davies, G.J.
Deposit date:2007-01-18
Release date:2007-03-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Characterization and Three-Dimensional Structures of Two Distinct Bacterial Xyloglucanases from Families Gh5 and Gh12.
J.Biol.Chem., 282, 2007
2JEQ
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FAMILY 5 XYLOGLUCANASE FROM PAENIBACILLUS PABULI IN COMPLEX WITH LIGAND
Descriptor:XYLOGLUCANASE, BETA-D-GLUCOSE, XYLOPYRANOSE, ...
Authors:Gloster, T.M., Ibatullin, F.M., Macauley, K., Eklof, J.M., Roberts, S., Turkenburg, J.P., Bjornvad, M.E., Jorgensen, P.L., Danielsen, S., Johansen, K., Borchert, T.V., Wilson, K.S., Brumer, H., Davies, G.J.
Deposit date:2007-01-18
Release date:2007-03-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Characterization and Three-Dimensional Structures of Two Distinct Bacterial Xyloglucanases from Families Gh5 and Gh12.
J.Biol.Chem., 282, 2007
2JF4
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FAMILY 37 TREHALASE FROM ESCHERICHIA COLI IN COMPLEX WITH VALIDOXYLAMINE
Descriptor:PERIPLASMIC TREHALASE, (1S,2S,3R,6S)-4-(HYDROXYMETHYL)-6-{[(1S,2S,3S,4R,5R)-2,3,4-TRIHYDROXY-5-(HYDROXYMETHYL)CYCLOHEXYL]AMINO}CYCLOHEX-4-ENE-1,2,3-TRIOL
Authors:Gibson, R.P., Gloster, T.M., Roberts, S., Warren, R.A.J., Storch De Gracia, I., Garcia, A., Chiara, J.L., Davies, G.J.
Deposit date:2007-01-25
Release date:2007-02-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Molecular Basis for Trehalase Inhibition Revealed by the Structure of Trehalase in Complex with Potent Inhibitors.
Angew.Chem.Int.Ed.Engl., 46, 2007
2JG0
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FAMILY 37 TREHALASE FROM ESCHERICHIA COLI IN COMPLEX WITH 1- THIATREHAZOLIN
Descriptor:PERIPLASMIC TREHALASE, N-[(3AS,4R,5S,6S,6AS)-4,5,6-TRIHYDROXY-4-(HYDROXYMETHYL)-4,5,6,6A-TETRAHYDRO-3AH-CYCLOPENTA[D][1,3]THIAZOL-2-YL]-ALPHA-D-GLUCOPYRANOSYLAMINE
Authors:Gibson, R.P., Gloster, T.M., Roberts, S., Warren, R.A.J., Storch De Gracia, I., Garcia, A., Chiara, J.L., Davies, G.J.
Deposit date:2007-02-07
Release date:2007-02-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Molecular Basis for Trehalase Inhibition Revealed by the Structure of Trehalase in Complex with Potent Inhibitors.
Angew.Chem.Int.Ed.Engl., 46, 2007
2JJB
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FAMILY 37 TREHALASE FROM ESCHERICHIA COLI IN COMPLEX WITH CASUARINE-6- O-ALPHA-GLUCOPYRANOSE
Descriptor:PERIPLASMIC TREHALASE, CASUARINE, ALPHA-D-GLUCOSE, ...
Authors:Gloster, T.M., Roberts, S., Davies, G.J., Cardona, F., Parmeggiani, C., Bonaccini, C., Gratteri, P., Sim, L., Rose, D.R., Goti, A.
Deposit date:2008-03-28
Release date:2009-01-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Total Syntheses of Casuarine and its 6-O-Alpha-Glucoside: Complementary Inhibition Towards Glycoside Hydrolases of the Gh31 and Gh37 Families.
Chemistry, 15, 2009
2JJM
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CRYSTAL STRUCTURE OF A FAMILY GT4 GLYCOSYLTRANSFERASE FROM BACILLUS ANTHRACIS ORF BA1558.
Descriptor:GLYCOSYL TRANSFERASE, GROUP 1 FAMILY PROTEIN
Authors:Ruane, K.M., Davies, G.J., Martinez-Fleites, C.
Deposit date:2008-04-15
Release date:2008-08-05
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Crystal Structure of a Family Gt4 Glycosyltransferase from Bacillus Anthracis Orf Ba1558.
Proteins, 73, 2008
2JKA
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NATIVE STRUCTURE OF A FAMILY 97 ALPHA-GLUCOSIDASE FROM BACTEROIDES THETAIOTAOMICRON
Descriptor:ALPHA-GLUCOSIDASE (ALPHA-GLUCOSIDASE SUSB), CALCIUM ION, 1,2-ETHANEDIOL
Authors:Gloster, T.M., Turkenburg, J.P., Potts, J.R., Henrissat, B., Davies, G.J.
Deposit date:2008-08-23
Release date:2008-09-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Divergence of Catalytic Mechanism within a Glycosidase Family Provides Insight Into Evolution of Carbohydrate Metabolism by Human Gut Flora.
Chem.Biol., 15, 2008
2JKE
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STRUCTURE OF A FAMILY 97 ALPHA-GLUCOSIDASE FROM BACTEROIDES THETAIOTAOMICRON IN COMPLEX WITH DEOXYNOJIRIMYCIN
Descriptor:ALPHA-GLUCOSIDASE (ALPHA-GLUCOSIDASE SUSB), 1-DEOXYNOJIRIMYCIN, CALCIUM ION, ...
Authors:Gloster, T.M., Turkenburg, J.P., Potts, J.R., Henrissat, B., Davies, G.J.
Deposit date:2008-08-28
Release date:2008-09-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Divergence of Catalytic Mechanism within a Glycosidase Family Provides Insight Into Evolution of Carbohydrate Metabolism by Human Gut Flora.
Chem.Biol., 15, 2008
2JKP
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STRUCTURE OF A FAMILY 97 ALPHA-GLUCOSIDASE FROM BACTEROIDES THETAIOTAOMICRON IN COMPLEX WITH CASTANOSPERMINE
Descriptor:ALPHA-GLUCOSIDASE (ALPHA-GLUCOSIDASE SUSB), CASTANOSPERMINE, CALCIUM ION, ...
Authors:Gloster, T.M., Turkenburg, J.P., Potts, J.R., Henrissat, B., Davies, G.J.
Deposit date:2008-08-29
Release date:2008-09-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Divergence of Catalytic Mechanism within a Glycosidase Family Provides Insight Into Evolution of Carbohydrate Metabolism by Human Gut Flora.
Chem.Biol., 15, 2008
2V38
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FAMILY 5 ENDOGLUCANASE CEL5A FROM BACILLUS AGARADHAERENS IN COMPLEX WITH CELLOBIO-DERIVED NOEUROMYCIN
Descriptor:ENDOGLUCANASE 5A, GLYCEROL, SULFATE ION, ...
Authors:Gloster, T.M., Meloncelli, P.J., Money, V.A., Tarling, C.A., Davies, G.J., Withers, S.G., Stick, R.V.
Deposit date:2007-06-13
Release date:2007-06-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:D-Glucosylated Derivatives of Isofagomine and Noeuromycin and Their Potential as Inhibitors of Beta-Glycoside Hydrolases
To be Published
2V3G
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STRUCTURE OF A FAMILY 26 LICHENASE IN COMPLEX WITH NOEUROMYCIN
Descriptor:ENDOGLUCANASE H, BETA-D-GLUCOSE, (2R,3S,4R,5R)-5-(HYDROXYMETHYL)PIPERIDINE-2,3,4-TRIOL
Authors:Meloncelli, P.J., Gloster, T.M., Money, V.A., Tarling, C.A., Davies, G.J., Withers, S.G., Stick, R.V.
Deposit date:2007-06-18
Release date:2007-09-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:D-Glucosylated Derivatives of Isofagomine and Noeuromycin and Their Potential as Inhibitors of Beta-Glycoside Hydrolases
To be Published
2VCE
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CHARACTERIZATION AND ENGINEERING OF THE BIFUNCTIONAL N- AND O- GLUCOSYLTRANSFERASE INVOLVED IN XENOBIOTIC METABOLISM IN PLANTS
Descriptor:HYDROQUINONE GLUCOSYLTRANSFERASE, URIDINE-5'-DIPHOSPHATE-2-DEOXY-2-FLUORO-ALPHA-D-GLUCOSE, 2,4,5-trichlorophenol, ...
Authors:Brazier-Hicks, M., Offen, W.A., Gershater, M.C., Revett, T.J., Lim, E.K., Bowles, D.J., Davies, G.J., Edwards, R.
Deposit date:2007-09-20
Release date:2007-10-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Characterization and Engineering of the Bifunctional N- and O-Glucosyltransferase Involved in Xenobiotic Metabolism in Plants.
Proc.Natl.Acad.Sci.USA, 104, 2007
2VCH
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CHARACTERIZATION AND ENGINEERING OF THE BIFUNCTIONAL N- AND O- GLUCOSYLTRANSFERASE INVOLVED IN XENOBIOTIC METABOLISM IN PLANTS
Descriptor:HYDROQUINONE GLUCOSYLTRANSFERASE, URIDINE-5'-DIPHOSPHATE, 1,2-ETHANEDIOL
Authors:Brazier-Hicks, M., Offen, W.A., Gershater, M.C., Revett, T.J., Lim, E.K., Bowles, D.J., Davies, G.J., Edwards, R.
Deposit date:2007-09-24
Release date:2007-10-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Characterization and Engineering of the Bifunctional N- and O-Glucosyltransferase Involved in Xenobiotic Metabolism in Plants.
Proc.Natl.Acad.Sci.USA, 104, 2007
2VG8
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CHARACTERIZATION AND ENGINEERING OF THE BIFUNCTIONAL N- AND O- GLUCOSYLTRANSFERASE INVOLVED IN XENOBIOTIC METABOLISM IN PLANTS
Descriptor:HYDROQUINONE GLUCOSYLTRANSFERASE, URIDINE-5'-DIPHOSPHATE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ...
Authors:Brazier-Hicks, M., Offen, W.A., Gershater, M.C., Revett, T.J., Lim, E.K., Bowles, D.J., Davies, G.J., Edwards, R.
Deposit date:2007-11-09
Release date:2007-12-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Characterization and Engineering of the Bifunctional N- and O-Glucosyltransferase Involved in Xenobiotic Metabolism in Plants.
Proc.Natl.Acad.Sci.USA, 104, 2007
2VHL
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THE THREE-DIMENSIONAL STRUCTURE OF THE N-ACETYLGLUCOSAMINE-6- PHOSPHATE DEACETYLASE FROM BACILLUS SUBTILIS
Descriptor:N-ACETYLGLUCOSAMINE-6-PHOSPHATE DEACETYLASE, GLUCOSAMINE 6-PHOSPHATE, TRIETHYLENE GLYCOL, ...
Authors:Vincent, F., Yates, D., Garman, E., Davies, G.J.
Deposit date:2007-11-22
Release date:2007-12-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:The Three-Dimensional Structure of the N-Acetylglucosamine-6-Phosphate Deacetylase from Bacillus Subtilis
J.Biol.Chem., 279, 2004
2VJX
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STRUCTURAL AND BIOCHEMICAL EVIDENCE FOR A BOAT-LIKE TRANSITION STATE IN BETA-MANNOSIDASES
Descriptor:BETA-MANNOSIDASE, (3S,4R,5R)-3,4-DIHYDROXY-5-(HYDROXYMETHYL)PIPERIDIN-2-ONE, 1,2-ETHANEDIOL, ...
Authors:Tailford, L.E., Offen, W.A., Smith, N.L., Dumon, C., Moreland, C., Gratien, J., Heck, M.P., Stick, R.V., Bleriot, Y., Vasella, A., Gilbert, H.J., Davies, G.J.
Deposit date:2007-12-14
Release date:2008-04-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural and Biochemical Evidence for a Boat-Like Transition State in Beta-Mannosidases.
Nat.Chem.Biol., 4, 2008
2VL4
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STRUCTURAL AND BIOCHEMICAL EVIDENCE FOR A BOAT-LIKE TRANSITION STATE IN BETA-MANNOSIDASES
Descriptor:BETA-MANNOSIDASE, (2S,3S,4R,5R)-2,3,4-TRIHYDROXY-5-HYDROXYMETHYL-PIPERIDINE, 1,2-ETHANEDIOL, ...
Authors:Tailford, L.E., Offen, W.A., Smith, N.L., Dumon, C., Moreland, C., Gratien, J., Heck, M.P., Stick, R.V., Bleriot, Y., Vasella, A., Gilbert, H.J., Davies, G.J.
Deposit date:2008-01-08
Release date:2008-04-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural and Biochemical Evidence for a Boat-Like Transition State in Beta-Mannosidases.
Nat.Chem.Biol., 4, 2008
2VMF
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STRUCTURAL AND BIOCHEMICAL EVIDENCE FOR A BOAT-LIKE TRANSITION STATE IN BETA-MANNOSIDASES
Descriptor:BETA-MANNOSIDASE, (5R,6R,7S,8R)-5-(HYDROXYMETHYL)-5,6,7,8-TETRAHYDROIMIDAZO[1,2-A]PYRIDINE-6,7,8-TRIOL, 1,2-ETHANEDIOL, ...
Authors:Tailford, L.E., Offen, W.A., Smith, N.L., Dumon, C., Moreland, C., Gratien, J., Heck, M.P., Stick, R.V., Bleriot, Y., Vasella, A., Gilbert, H.J., Davies, G.J.
Deposit date:2008-01-25
Release date:2008-04-01
Last modified:2018-11-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural and Biochemical Evidence for a Boat-Like Transition State in Beta-Mannosidases.
Nat.Chem.Biol., 4, 2008
2VN5
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THE CLOSTRIDIUM CELLULOLYTICUM DOCKERIN DISPLAYS A DUAL BINDING MODE FOR ITS COHESIN PARTNER
Descriptor:SCAFFOLDING PROTEIN, ENDOGLUCANASE A, CALCIUM ION
Authors:Pinheiro, B.A., Prates, J.A.M., Proctor, M.R., Gilbert, H.J., Davies, G.J., Money, V.A., Martinez-Fleites, C., Bayer, E.A., Fontes, C.M.G.A., Fierobe, H.P.
Deposit date:2008-01-31
Release date:2008-05-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The Clostridium Cellulolyticum Dockerin Displays a Dual Binding Mode for its Cohesin Partner.
J.Biol.Chem., 283, 2008
2VN6
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THE CLOSTRIDIUM CELLULOLYTICUM DOCKERIN DISPLAYS A DUAL BINDING MODE FOR ITS COHESIN PARTNER
Descriptor:SCAFFOLDING PROTEIN, ENDOGLUCANASE A, CALCIUM ION
Authors:Pinheiro, B.A., Prates, J.A.M., Proctor, M.R., Gilbert, H.J., Davies, G.J., Money, V.A., Martinez-Fleites, C., Bayer, E.A., Fontes, C.M.G.A., Fierobe, H.P.
Deposit date:2008-01-31
Release date:2008-05-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.49 Å)
Cite:The Clostridium Cellulolyticum Dockerin Displays a Dual Binding Mode for its Cohesin Partner.
J.Biol.Chem., 283, 2008
2VO5
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STRUCTURAL AND BIOCHEMICAL EVIDENCE FOR A BOAT-LIKE TRANSITION STATE IN BETA-MANNOSIDASES
Descriptor:BETA-MANNOSIDASE, (1R,4R,5R,7R,8R)-2-Benzyl-5-hydroxymethyl-2-aza-bicyclo[2.2.2]octane-4,7,8-triol, 1,2-ETHANEDIOL, ...
Authors:Tailford, L.E., Offen, W.A., Smith, N.L., Dumon, C., Moreland, C., Gratien, J., Heck, M.P., Stick, R.V., Bleriot, Y., Vasella, A., Gilbert, H.J., Davies, G.J.
Deposit date:2008-02-08
Release date:2008-04-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural and Biochemical Evidence for a Boat-Like Transition State in Beta-Mannosidases.
Nat.Chem.Biol., 4, 2008
2VOT
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STRUCTURAL AND BIOCHEMICAL EVIDENCE FOR A BOAT-LIKE TRANSITION STATE IN BETA-MANNOSIDASES
Descriptor:BETA-MANNOSIDASE, (5R,6R,7S,8R)-6,7,8-trihydroxy-5-(hydroxymethyl)-2-[(phenylamino)methyl]-5,6,7,8-tetrahydro-1H-imidazo[1,2-a]pyridin-4-ium, 1,2-ETHANEDIOL, ...
Authors:Tailford, L.N., Offen, W.A., Smith, N., Dumon, C., Moreland, C., Gratien, J., Heck, M.-P., Stick, R.V., Bleriot, Y., Vasella, A., Gilbert, H.J., Davies, G.J.
Deposit date:2008-02-20
Release date:2008-04-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural and Biochemical Evidence for a Boat-Like Transition State in Beta-Mannosidases.
Nat.Chem.Biol., 4, 2008
2VQT
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STRUCTURAL AND BIOCHEMICAL EVIDENCE FOR A BOAT-LIKE TRANSITION STATE IN BETA-MANNOSIDASES
Descriptor:BETA-MANNOSIDASE, (2Z,3R,4S,5R,6R)-2-[(2-aminoethyl)imino]-6-(hydroxymethyl)piperidine-3,4,5-triol, 1,2-ETHANEDIOL, ...
Authors:Tailford, L.E., Offen, W.A., Smith, N.L., Dumon, C., Moreland, C., Gratien, J., Heck, M.P., Stick, R.V., Bleriot, Y., Vasella, A., Gilbert, H.J., Davies, G.J.
Deposit date:2008-03-18
Release date:2008-04-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural and Biochemical Evidence for a Boat-Like Transition State in Beta-Mannosidases.
Nat.Chem.Biol., 4, 2008
2VQU
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STRUCTURAL AND BIOCHEMICAL EVIDENCE FOR A BOAT-LIKE TRANSITION STATE IN BETA-MANNOSIDASES
Descriptor:BETA-MANNOSIDASE, 1,2-ETHANEDIOL, (2R,3S,4R,5R)-5-(HYDROXYMETHYL)PIPERIDINE-2,3,4-TRIOL, ...
Authors:Tailford, L.E., Offen, W.A., Smith, N.L., Dumon, C., Moreland, C., Gratien, J., Heck, M.P., Stick, R.V., Bleriot, Y., Vasella, A., Gilbert, H.J., Davies, G.J.
Deposit date:2008-03-18
Release date:2008-04-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural and Biochemical Evidence for a Boat-Like Transition State in Beta-Mannosidases.
Nat.Chem.Biol., 4, 2008
2VR4
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TRANSITION-STATE MIMICRY IN MANNOSIDE HYDROLYSIS: CHARACTERISATION OF TWENTY SIX INHIBITORS AND INSIGHT INTO BINDING FROM LINEAR FREE ENERGY RELATIONSHIPS AND 3-D STRUCTURE
Descriptor:BETA-MANNOSIDASE, (2Z,3R,4S,5R,6R)-2-[(4-aminobutyl)imino]-6-(hydroxymethyl)piperidine-3,4,5-triol, 1,2-ETHANEDIOL, ...
Authors:Tailford, L.E., Offen, W.A., Smith, N.L., Dumon, C., Moreland, C., Gratien, J., Heck, M.P., Stick, R.V., Bleriot, Y., Vasella, A., Gilbert, H.J., Davies, G.J.
Deposit date:2008-03-25
Release date:2008-04-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural and Biochemical Evidence for a Boat-Like Transition State in Beta-Mannosidases.
Nat.Chem.Biol., 4, 2008