Author results

4GMB
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CRYSTAL STRUCTURE OF HUMAN WD REPEAT DOMAIN 5 WITH COMPOUND MM-402
Descriptor:WD repeat-containing protein 5, MM-402
Authors:Karatas, H., Townsend, E.C., Chen, Y., Bernard, D., Cao, F., Liu, L., Lei, M., Dou, Y., Wang, S.
Deposit date:2012-08-15
Release date:2014-02-19
Last modified:2017-06-28
Method:X-RAY DIFFRACTION (2.781 Å)
Cite:Discovery of a Highly Potent, Cell-Permeable Macrocyclic Peptidomimetic (MM-589) Targeting the WD Repeat Domain 5 Protein (WDR5)-Mixed Lineage Leukemia (MLL) Protein-Protein Interaction.
J. Med. Chem., 2017
4XSQ
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STRUCTURE OF A VARIABLE LYMPHOCYTE RECEPTOR-LIKE PROTEIN BF66946 FROM BRANCHIOSTOMA FLORIDAE
Descriptor:variable lymphocyte receptor-like protein Bf66946, 1,2-ETHANEDIOL, GLYCEROL
Authors:Cao, D.D., Cheng, W., Jiang, Y.L., Wang, W.J., Li, Q., Chen, Y., Zhou, C.Z.
Deposit date:2015-01-22
Release date:2016-03-23
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Structure of a variable lymphocyte receptor-like protein from the amphioxus Branchiostoma floridae.
Sci Rep, 6, 2016
4Y1L
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UBC9 HOMODIMER THE MISSING LINK IN POLY-SUMO CHAIN FORMATION
Descriptor:SUMO-conjugating enzyme UBC9, RWD domain-containing protein 3
Authors:Aileen, Y.A., Ambaye, N.D., Li, Y.J., Vega, R., Bzymek, K., Williams, J.C., Hu, W., Chen, Y.
Deposit date:2015-02-08
Release date:2015-05-06
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:RWD Domain as an E2 (Ubc9)-Interaction Module.
J.Biol.Chem., 290, 2015
5XU0
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STRUCTURE OF THE MEMBRANE FUSION PROTEIN SPR0693 FROM STREPTOCOCCUS PNEUMONIAE R6
Descriptor:Membrane-fusion protein
Authors:Yang, H.B., Jiang, Y.L., Hou, W.T., Chen, M.T., Chen, Y., Zhou, C.Z.
Deposit date:2017-06-22
Release date:2018-01-24
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Structure of a MacAB-like efflux pump from Streptococcus pneumoniae.
Nat Commun, 9, 2018
5XU1
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STRUCTURE OF A NON-CANONICAL ABC TRANSPORTER FROM STREPTOCOCCUS PNEUMONIAE R6
Descriptor:ABC transporter ATP-binding protein, ABC transporter permeae, MAGNESIUM ION
Authors:Yang, H.B., Jiang, Y.L., Hou, W.T., Chen, M.T., Chen, Y., Zhou, C.Z.
Deposit date:2017-06-22
Release date:2018-01-24
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structure of a MacAB-like efflux pump from Streptococcus pneumoniae.
Nat Commun, 9, 2018
5YBX
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CRYSTAL STRUCTURE OF THE N-TERMINAL DOMAIN OF BQT4 IN S.POMBE
Descriptor:Bouquet formation protein 4
Authors:Hu, C., Chen, Y.
Deposit date:2017-09-05
Release date:2018-09-19
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (2.501 Å)
Cite:The Inner Nuclear Membrane Protein Bqt4 in Fission Yeast Contains a DNA-Binding Domain Essential for Telomere Association with the Nuclear Envelope.
Structure, 27, 2019
1EV7
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CRYSTAL STRUCTURE OF DNA RESTRICTION ENDONUCLEASE NAEI
Descriptor:TYPE IIE RESTRICTION ENDONUCLEASE NAEI
Authors:Huai, Q., Colandene, J.D., Chen, Y., Luo, F., Zhao, Y.
Deposit date:2000-04-19
Release date:2000-10-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Crystal structure of NaeI-an evolutionary bridge between DNA endonuclease and topoisomerase.
EMBO J., 19, 2000
1FGL
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CYCLOPHILIN A COMPLEXED WITH A FRAGMENT OF HIV-1 GAG PROTEIN
Descriptor:CYCLOPHILIN A, HIV-1 GAG PROTEIN
Authors:Zhao, Y., Chen, Y., Schutkowski, M., Fischer, G., Ke, H.
Deposit date:1996-11-18
Release date:1997-04-01
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Cyclophilin A complexed with a fragment of HIV-1 gag protein: insights into HIV-1 infectious activity.
Structure, 5, 1997
1IAX
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CRYSTAL STRUCTURE OF ACC SYNTHASE COMPLEXED WITH PLP
Descriptor:1-AMINOCYCLOPROPANE-1-CARBOXYLATE SYNTHASE 2, SULFATE ION, PYRIDOXAL-5'-PHOSPHATE
Authors:Huai, Q., Xia, Y., Chen, Y., Callahan, B., Li, N., Ke, H.
Deposit date:2001-03-24
Release date:2001-04-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structures of 1-aminocyclopropane-1-carboxylate (ACC) synthase in complex with aminoethoxyvinylglycine and pyridoxal-5'-phosphate provide new insight into catalytic mechanisms
J.Biol.Chem., 276, 2001
1IAY
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CRYSTAL STRUCTURE OF ACC SYNTHASE COMPLEXED WITH COFACTOR PLP AND INHIBITOR AVG
Descriptor:1-AMINOCYCLOPROPANE-1-CARBOXYLATE SYNTHASE 2, PYRIDOXAL-5'-PHOSPHATE, 2-AMINO-4-(2-AMINO-ETHOXY)-BUTYRIC ACID
Authors:Huai, Q., Xia, Y., Chen, Y., Callahan, B., Li, N., Ke, H.
Deposit date:2001-03-24
Release date:2001-04-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structures of 1-aminocyclopropane-1-carboxylate (ACC) synthase in complex with aminoethoxyvinylglycine and pyridoxal-5'-phosphate provide new insight into catalytic mechanisms
J.Biol.Chem., 276, 2001
1MVO
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CRYSTAL STRUCTURE OF THE PHOP RECEIVER DOMAIN FROM BACILLUS SUBTILIS
Descriptor:PhoP response regulator, MANGANESE (II) ION, SODIUM ION
Authors:Birck, C., Chen, Y., Hulett, F.M., Samama, J.P., Structural Proteomics in Europe (SPINE)
Deposit date:2002-09-26
Release date:2002-10-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The Crystal Structure of the Phosphorylation Domain in PhoP Reveals a Functional Tandem Association Mediated by an Asymmetric Interface
J.BACTERIOL., 185, 2003
1VBT
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STRUCTURE OF CYCLOPHILIN COMPLEXED WITH SULFUR-SUBSTITUTED TETRAPEPTIDE AAPF
Descriptor:CYCLOPHILIN A, SULFUR-SUBSTITUTED TETRAPEPTIDE
Authors:Zhao, Y., Chen, Y., Schutkowski, M., Fischer, G., Ke, H.
Deposit date:1998-06-16
Release date:1999-01-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Insight Into Conversion of Substrate to Inhibitor
To be Published
1XKL
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CRYSTAL STRUCTURE OF SALICYLIC ACID-BINDING PROTEIN 2 (SABP2) FROM NICOTIANA TABACUM, NESG TARGET AR2241
Descriptor:salicylic acid-binding protein 2, 2-AMINO-4H-1,3-BENZOXATHIIN-4-OL
Authors:Forouhar, F., Chen, Y., Chiang, Y., Acton, T.B., Montelione, G.T., Hunt, J.F., Tong, L., Northeast Structural Genomics Consortium (NESG)
Deposit date:2004-09-29
Release date:2004-11-30
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural and biochemical studies identify tobacco SABP2 as a methyl salicylate esterase and implicate it in plant innate immunity
Proc.Natl.Acad.Sci.USA, 102, 2005
1ZKL
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MULTIPLE DETERMINANTS FOR INHIBITOR SELECTIVITY OF CYCLIC NUCLEOTIDE PHOSPHODIESTERASES
Descriptor:High-affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A, ZINC ION, MAGNESIUM ION, ...
Authors:Wang, H., Liu, Y., Chen, Y., Robinson, H., Ke, H.
Deposit date:2005-05-03
Release date:2005-07-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:Multiple elements jointly determine inhibitor selectivity of cyclic nucleotide phosphodiesterases 4 and 7
J.Biol.Chem., 280, 2005
2B34
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STRUCTURE OF MAR1 RIBONUCLEASE FROM CAENORHABDITIS ELEGANS
Descriptor:MAR1 Ribonuclease
Authors:Schormann, N., Karpova, E., Li, S., Symersky, J., Zhang, Y., Lu, S., Zhou, Q., Lin, G., Cao, Z., Luo, M., Qiu, S., Luan, C.-H., Luo, D., Huang, W., Shang, Q., McKinstry, A., An, J., Tsao, J., Carson, M., Stinnett, M., Chen, Y., Johnson, D., Gary, R., Arabshahi, A., Bunzel, R., Bray, T., DeLucas, L., Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2005-09-19
Release date:2005-09-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.141 Å)
Cite:Structure of MAR1 Ribonuclease from Caenorhabditis elegans
To be Published
2FS1
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SOLUTION STRUCTURE OF PSD-1
Descriptor:PSD-1
Authors:He, Y., Rozak, D.A., Sari, N., Chen, Y., Bryan, P., Orban, J.
Deposit date:2006-01-20
Release date:2006-12-05
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure, dynamics, and stability variation in bacterial albumin binding modules: implications for species specificity.
Biochemistry, 45, 2006
2JWS
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SOLUTION NMR STRUCTURES OF TWO DESIGNED PROTEINS WITH 88% SEQUENCE IDENTITY BUT DIFFERENT FOLD AND FUNCTION
Descriptor:Ga88
Authors:He, Y., Chen, Y., Alexander, P., Bryan, P., Orban, J.
Deposit date:2007-10-24
Release date:2008-09-09
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:NMR structures of two designed proteins with high sequence identity but different fold and function
Proc.Natl.Acad.Sci.Usa, 105, 2008
2JWU
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SOLUTION NMR STRUCTURES OF TWO DESIGNED PROTEINS WITH 88% SEQUENCE IDENTITY BUT DIFFERENT FOLD AND FUNCTION
Descriptor:Gb88
Authors:He, Y., Chen, Y., Alexander, P., Bryan, P., Orban, J.
Deposit date:2007-10-25
Release date:2008-09-09
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:NMR structures of two designed proteins with high sequence identity but different fold and function
Proc.Natl.Acad.Sci.Usa, 105, 2008
2KDL
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NMR STRUCTURES OF GA95 AND GB95, TWO DESIGNED PROTEINS WITH 95% SEQUENCE IDENTITY BUT DIFFERENT FOLDS AND FUNCTIONS
Descriptor:designed protein
Authors:He, Y., Alexander, P., Chen, Y., Bryan, P., Orban, J.
Deposit date:2009-01-12
Release date:2009-12-29
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:A minimal sequence code for switching protein structure and function.
Proc.Natl.Acad.Sci.USA, 106, 2009
2KDM
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NMR STRUCTURES OF GA95 AND GB95, TWO DESIGNED PROTEINS WITH 95% SEQUENCE IDENTITY BUT DIFFERENT FOLDS AND FUNCTIONS
Descriptor:DESIGNED PROTEIN
Authors:He, Y., Alexander, P., Chen, Y., Bryan, P., Orban, J.
Deposit date:2009-01-12
Release date:2009-12-29
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:From the Cover: A minimal sequence code for switching protein structure and function.
Proc.Natl.Acad.Sci.USA, 106, 2009
2LHC
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GA98 SOLUTION STRUCTURE
Descriptor:Ga98
Authors:He, Y., Chen, Y., Alexander, P., Bryan, P., Orban, J.
Deposit date:2011-08-08
Release date:2012-02-29
Method:SOLUTION NMR
Cite:Mutational tipping points for switching protein folds and functions.
Structure, 20, 2012
2LHD
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GB98 SOLUTION STRUCTURE
Descriptor:GB98
Authors:He, Y., Chen, Y., Alexander, P., Bryan, P., Orban, J.
Deposit date:2011-08-08
Release date:2012-02-29
Method:SOLUTION NMR
Cite:Mutational tipping points for switching protein folds and functions.
Structure, 20, 2012
2LHE
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GB98-T25I,L20A
Descriptor:Gb98
Authors:He, Y., Chen, Y., Alexander, P., Bryan, P., Orban, J.
Deposit date:2011-08-08
Release date:2012-02-29
Method:SOLUTION NMR
Cite:Mutational tipping points for switching protein folds and functions.
Structure, 20, 2012
2LHG
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GB98-T25I SOLUTION STRUCTURE
Descriptor:GB98
Authors:He, Y., Chen, Y., Alexander, P., Bryan, P., Orban, J.
Deposit date:2011-08-08
Release date:2012-02-29
Method:SOLUTION NMR
Cite:Mutational tipping points for switching protein folds and functions.
Structure, 20, 2012
2LU1
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PFSUB2 SOLUTION NMR STRUCTURE
Descriptor:Subtilase
Authors:He, Y., Chen, Y., Ruan, B., O'Brochta, D., Bryan, P., Orban, J.
Deposit date:2012-06-06
Release date:2012-10-03
Last modified:2012-11-14
Method:SOLUTION NMR
Cite:Solution NMR structure of a sheddase inhibitor prodomain from the malarial parasite Plasmodium falciparum.
Proteins, 80, 2012