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7SGZ
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BU of 7sgz by Molmil
Structure of the yeast Rad24-RFC loader bound to DNA and the closed 9-1-1 clamp
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Checkpoint protein RAD24, Crick strand, ...
Authors:Zheng, F, Georgescu, R, Yao, Y.N, O'Donnell, M.E, Li, H.
Deposit date:2021-10-07
Release date:2022-03-23
Last modified:2022-04-27
Method:ELECTRON MICROSCOPY (3.17 Å)
Cite:DNA is loaded through the 9-1-1 DNA checkpoint clamp in the opposite direction of the PCNA clamp.
Nat.Struct.Mol.Biol., 29, 2022
7SH2
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BU of 7sh2 by Molmil
Structure of the yeast Rad24-RFC loader bound to DNA and the open 9-1-1 clamp
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Checkpoint protein RAD24, Crick strand, ...
Authors:Zheng, F, Georgescu, R, Yao, Y.N, O'Donnell, M.E, Li, H.
Deposit date:2021-10-07
Release date:2022-03-23
Last modified:2022-04-27
Method:ELECTRON MICROSCOPY (3.23 Å)
Cite:DNA is loaded through the 9-1-1 DNA checkpoint clamp in the opposite direction of the PCNA clamp.
Nat.Struct.Mol.Biol., 29, 2022
7TFH
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BU of 7tfh by Molmil
Atomic model of the S. cerevisiae clamp-clamp loader complex PCNA-RFC bound to two DNA molecules, one at the 5'-recessed end and the other at the 3'-recessed end
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ...
Authors:Zheng, F, Georgescu, R, Yao, Y.N, O'Donnell, M.E, Li, H.
Deposit date:2022-01-06
Release date:2022-11-16
Method:ELECTRON MICROSCOPY (3.09 Å)
Cite:Cryo-EM structures reveal that RFC recognizes both the 3'- and 5'-DNA ends to load PCNA onto gaps for DNA repair.
Elife, 11, 2022
7TFK
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BU of 7tfk by Molmil
Atomic model of S. cerevisiae clamp loader RFC bound to two DNA molecules, one at the 5'-recessed end and the other at the 3'-recessed end
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ...
Authors:Zheng, F, Georgescu, R, Yao, Y.N, O'Donnell, M.E, Li, H.
Deposit date:2022-01-06
Release date:2022-11-16
Method:ELECTRON MICROSCOPY (3.25 Å)
Cite:Cryo-EM structures reveal that RFC recognizes both the 3'- and 5'-DNA ends to load PCNA onto gaps for DNA repair.
Elife, 11, 2022
7TFL
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BU of 7tfl by Molmil
Atomic model of S. cerevisiae clamp loader RFC bound to DNA
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ...
Authors:Zheng, F, Georgescu, R, Yao, Y.N, O'Donnell, M.E, Li, H.
Deposit date:2022-01-06
Release date:2022-11-16
Method:ELECTRON MICROSCOPY (3.33 Å)
Cite:Cryo-EM structures reveal that RFC recognizes both the 3'- and 5'-DNA ends to load PCNA onto gaps for DNA repair.
Elife, 11, 2022
7TFI
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BU of 7tfi by Molmil
Atomic model of the S. cerevisiae clamp-clamp loader complex PCNA-RFC bound to DNA with an open clamp
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ...
Authors:Zheng, F, Georgescu, R, Yao, Y.N, O'Donnell, M.E, Li, H.
Deposit date:2022-01-06
Release date:2022-11-16
Method:ELECTRON MICROSCOPY (3.41 Å)
Cite:Cryo-EM structures reveal that RFC recognizes both the 3'- and 5'-DNA ends to load PCNA onto gaps for DNA repair.
Elife, 11, 2022
7TFJ
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BU of 7tfj by Molmil
Atomic model of S. cerevisiae clamp-clamp loader complex PCNA-RFC bound to DNA with a closed clamp ring
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ...
Authors:Zheng, F, Georgescu, R, Yao, Y.N, O'Donnell, M.E, Li, H.
Deposit date:2022-01-06
Release date:2022-11-16
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Cryo-EM structures reveal that RFC recognizes both the 3'- and 5'-DNA ends to load PCNA onto gaps for DNA repair.
Elife, 11, 2022
8FS6
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BU of 8fs6 by Molmil
Structure of S. cerevisiae Rad24-RFC loading the 9-1-1 clamp onto a 10-nt gapped DNA in step 4 (partially closed 9-1-1 and stably bound chamber DNA)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Checkpoint protein RAD24, DDC1 isoform 1, ...
Authors:Zheng, F, Georgescu, R, Yao, Y.N, O'Donnell, M.E, Li, H.
Deposit date:2023-01-09
Release date:2023-06-14
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structures of 9-1-1 DNA checkpoint clamp loading at gaps from start to finish and ramification to biology.
Biorxiv, 2023
8FS4
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BU of 8fs4 by Molmil
Structure of S. cerevisiae Rad24-RFC loading the 9-1-1 clamp onto a 10-nt gapped DNA in step 2 (open 9-1-1 ring and flexibly bound chamber DNA)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Checkpoint protein RAD24, DDC1 isoform 1, ...
Authors:Zheng, F, Georgescu, R, Yao, Y.N, O'Donnell, M.E, Li, H.
Deposit date:2023-01-09
Release date:2023-06-14
Method:ELECTRON MICROSCOPY (2.94 Å)
Cite:Structures of 9-1-1 DNA checkpoint clamp loading at gaps from start to finish and ramification to biology.
Biorxiv, 2023
8FS7
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BU of 8fs7 by Molmil
Structure of S. cerevisiae Rad24-RFC loading the 9-1-1 clamp onto a 10-nt gapped DNA in step 5 (closed 9-1-1 and stably bound chamber DNA)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Checkpoint protein RAD24, DDC1 isoform 1, ...
Authors:Zheng, F, Georgescu, R, Yao, Y.N, O'Donnell, M.E, Li, H.
Deposit date:2023-01-09
Release date:2023-06-14
Method:ELECTRON MICROSCOPY (2.85 Å)
Cite:Structures of 9-1-1 DNA checkpoint clamp loading at gaps from start to finish and ramification to biology.
Biorxiv, 2023
8FS8
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BU of 8fs8 by Molmil
Structure of S. cerevisiae Rad24-RFC loading the 9-1-1 clamp onto a 5-nt gapped DNA (9-1-1 encircling fully bound DNA)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Checkpoint protein RAD24, DDC1 isoform 1, ...
Authors:Zheng, F, Georgescu, R, Yao, Y.N, O'Donnell, M.E, Li, H.
Deposit date:2023-01-09
Release date:2023-06-14
Method:ELECTRON MICROSCOPY (3.04 Å)
Cite:Structures of 9-1-1 DNA checkpoint clamp loading at gaps from start to finish and ramification to biology.
Biorxiv, 2023
8FS5
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BU of 8fs5 by Molmil
Structure of S. cerevisiae Rad24-RFC loading the 9-1-1 clamp onto a 10-nt gapped DNA in step 3 (open 9-1-1 and stably bound chamber DNA)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Checkpoint protein RAD24, DDC1 isoform 1, ...
Authors:Zheng, F, Georgescu, R, Yao, Y.N, O'Donnell, M.E, Li, H.
Deposit date:2023-01-09
Release date:2023-06-14
Method:ELECTRON MICROSCOPY (2.76 Å)
Cite:Structures of 9-1-1 DNA checkpoint clamp loading at gaps from start to finish and ramification to biology.
Biorxiv, 2023
8FS3
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BU of 8fs3 by Molmil
Structure of S. cerevisiae Rad24-RFC loading the 9-1-1 clamp onto a 10-nt gapped DNA in step 1 (open 9-1-1 and shoulder bound DNA only)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Checkpoint protein RAD24, DDC1 isoform 1, ...
Authors:Zheng, F, Georgescu, R, Yao, Y.N, O'Donnell, M.E, Li, H.
Deposit date:2023-01-09
Release date:2023-06-14
Method:ELECTRON MICROSCOPY (2.93 Å)
Cite:Structures of 9-1-1 DNA checkpoint clamp loading at gaps from start to finish and ramification to biology.
Biorxiv, 2023
5WX1
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BU of 5wx1 by Molmil
The closed-conformation crystal structure of the full-length pestivirus NS3 with its NS4A protease cofactor segment
Descriptor: Serine protease NS3
Authors:Zheng, F, Lu, G, Gong, P.
Deposit date:2017-01-06
Release date:2017-08-23
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Uncoupling of Protease trans-Cleavage and Helicase Activities in Pestivirus NS3.
J. Virol., 91, 2017
7KC0
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BU of 7kc0 by Molmil
Structure of the Saccharomyces cerevisiae replicative polymerase delta in complex with a primer/template and the PCNA clamp
Descriptor: 2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE, DNA (25-MER), DNA (5'-D(P*AP*TP*GP*AP*CP*CP*AP*TP*GP*AP*TP*TP*AP*CP*GP*AP*AP*TP*TP*GP*C)-3'), ...
Authors:Zheng, F, Georgescu, R, Li, H, O'Donnell, M.E.
Deposit date:2020-10-04
Release date:2020-12-02
Last modified:2020-12-16
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structure of eukaryotic DNA polymerase delta bound to the PCNA clamp while encircling DNA.
Proc.Natl.Acad.Sci.USA, 117, 2020
4KRD
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BU of 4krd by Molmil
Crystal Structure of Pho85-Pcl10 Complex
Descriptor: Cyclin-dependent protein kinase PHO85, PHO85 cyclin-10
Authors:Quiocho, F.A, Zheng, F.
Deposit date:2013-05-16
Release date:2013-09-18
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.952 Å)
Cite:New Structural Insights into Phosphorylation-free Mechanism for Full Cyclin-dependent Kinase (CDK)-Cyclin Activity and Substrate Recognition.
J.Biol.Chem., 288, 2013
4KRC
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BU of 4krc by Molmil
Crystal Structure of Pho85-Pcl10-ATP-gamma-S Complex
Descriptor: Cyclin-dependent protein kinase PHO85, MAGNESIUM ION, PHO85 cyclin-10, ...
Authors:Quiocho, F.A, Zheng, F.
Deposit date:2013-05-16
Release date:2013-09-18
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.597 Å)
Cite:New Structural Insights into Phosphorylation-free Mechanism for Full Cyclin-dependent Kinase (CDK)-Cyclin Activity and Substrate Recognition.
J.Biol.Chem., 288, 2013
7EGT
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BU of 7egt by Molmil
The crystal structure of the C-terminal domain of T. thermophilus UvrD complexed with the N-terminal domain of UvrB
Descriptor: DNA helicase UvrD, UvrABC system protein B
Authors:Zheng, F, Shen, L, Li, L, Zhang, Y.
Deposit date:2021-03-26
Release date:2022-04-06
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.581 Å)
Cite:Crucial role and mechanism of transcription-coupled DNA repair in bacteria.
Nature, 604, 2022
7EGS
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BU of 7egs by Molmil
The crystal structure of lobe domain of E. coli RNA polymerase complexed with the C-terminal domain of UvrD
Descriptor: DNA helicase II, DNA-directed RNA polymerase subunit beta, GLYCEROL
Authors:Zheng, F, Shen, L, Li, L, Zhang, Y.
Deposit date:2021-03-26
Release date:2022-04-06
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crucial role and mechanism of transcription-coupled DNA repair in bacteria.
Nature, 604, 2022
1EIZ
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BU of 1eiz by Molmil
FTSJ RNA METHYLTRANSFERASE COMPLEXED WITH S-ADENOSYLMETHIONINE
Descriptor: FTSJ, S-ADENOSYLMETHIONINE
Authors:Bugl, H, Fauman, E.B, Staker, B.L, Zheng, F, Kushner, S.R, Saper, M.A, Bardwell, J.C.A, Jakob, U.
Deposit date:2000-02-29
Release date:2000-08-30
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:RNA methylation under heat shock control.
Mol.Cell, 6, 2000
1EJ0
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BU of 1ej0 by Molmil
FTSJ RNA METHYLTRANSFERASE COMPLEXED WITH S-ADENOSYLMETHIONINE, MERCURY DERIVATIVE
Descriptor: FTSJ, MERCURY (II) ION, S-ADENOSYLMETHIONINE
Authors:Bugl, H, Fauman, E.B, Staker, B.L, Zheng, F, Kushner, S.R, Saper, M.A, Bardwell, J.C.A, Jakob, U.
Deposit date:2000-02-29
Release date:2000-08-30
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:RNA methylation under heat shock control.
Mol.Cell, 6, 2000
5IMO
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BU of 5imo by Molmil
Nanobody targeting mouse Vsig4 in Spacegroup P3221
Descriptor: Nanobody, Protein Vsig4
Authors:Wen, Y, Zheng, F.
Deposit date:2016-03-06
Release date:2017-01-11
Last modified:2017-07-05
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural evaluation of a nanobody targeting complement receptor Vsig4 and its cross reactivity
Immunobiology, 222, 2017
5IMM
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BU of 5imm by Molmil
Nanobody targeting mouse Vsig4 in Spacegroup P212121
Descriptor: Nanobody, Protein Vsig4
Authors:Wen, Y, Zheng, F.
Deposit date:2016-03-06
Release date:2017-01-11
Last modified:2017-07-05
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Structural evaluation of a nanobody targeting complement receptor Vsig4 and its cross reactivity
Immunobiology, 222, 2017
3TJM
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BU of 3tjm by Molmil
Crystal Structure of the Human Fatty Acid Synthase Thioesterase Domain with an Activate Site-Specific Polyunsaturated Fatty Acyl Adduct
Descriptor: Fatty acid synthase, methyl (R)-(6Z,9Z,12Z)-octadeca-6,9,12-trien-1-ylphosphonofluoridate
Authors:Zhang, W, Zheng, F, Florante, A.Q.
Deposit date:2011-08-24
Release date:2011-09-28
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Crystal structure of FAS thioesterase domain with polyunsaturated fatty acyl adduct and inhibition by dihomo-gamma-linolenic acid.
Proc.Natl.Acad.Sci.USA, 108, 2011
7DJX
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BU of 7djx by Molmil
Clec4f Nanobody 246
Descriptor: Clec4f Nanobody 246
Authors:Wen, Y, Zheng, F.
Deposit date:2020-11-22
Release date:2021-11-24
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Clec4f Nanobody 246
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PDB entries from 2024-03-27

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