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1AQI
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BU of 1aqi by Molmil
STRUCTURE OF ADENINE-N6-DNA-METHYLTRANSFERASE TAQI
Descriptor: ADENINE-N6-DNA-METHYLTRANSFERASE TAQI, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Schluckebier, G, Saenger, W.
Deposit date:1996-07-25
Release date:1997-02-12
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Differential binding of S-adenosylmethionine S-adenosylhomocysteine and Sinefungin to the adenine-specific DNA methyltransferase M.TaqI.
J.Mol.Biol., 265, 1997
1AQJ
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BU of 1aqj by Molmil
STRUCTURE OF ADENINE-N6-DNA-METHYLTRANSFERASE TAQI
Descriptor: ADENINE-N6-DNA-METHYLTRANSFERASE TAQI, SINEFUNGIN
Authors:Schluckebier, G, Saenger, W.
Deposit date:1996-07-25
Release date:1997-02-12
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Differential binding of S-adenosylmethionine S-adenosylhomocysteine and Sinefungin to the adenine-specific DNA methyltransferase M.TaqI.
J.Mol.Biol., 265, 1997
2ADM
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BU of 2adm by Molmil
ADENINE-N6-DNA-METHYLTRANSFERASE TAQI
Descriptor: ADENINE-N6-DNA-METHYLTRANSFERASE TAQI, S-ADENOSYLMETHIONINE
Authors:Schluckebier, G, Saenger, W.
Deposit date:1996-07-15
Release date:1997-01-27
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Differential binding of S-adenosylmethionine S-adenosylhomocysteine and Sinefungin to the adenine-specific DNA methyltransferase M.TaqI.
J.Mol.Biol., 265, 1997
1QAN
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BU of 1qan by Molmil
THE STRUCTURE OF THE RRNA METHYLTRANSFERASE ERMC': IMPLICATIONS FOR THE REACTION MECHANISM
Descriptor: ACETATE ION, ERMC' METHYLTRANSFERASE, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Schluckebier, G, Zhong, P, Stewart, K.D, Kavanaugh, T.J, Abad-Zapatero, C.
Deposit date:1999-03-26
Release date:2000-03-29
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The 2.2 A structure of the rRNA methyltransferase ErmC' and its complexes with cofactor and cofactor analogs: implications for the reaction mechanism.
J.Mol.Biol., 289, 1999
1QAO
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BU of 1qao by Molmil
THE STRUCTURE OF THE RRNA METHYLTRANSFERASE ERMC': IMPLICATIONS FOR THE REACTION MECHANISM
Descriptor: ERMC' METHYLTRANSFERASE, S-ADENOSYLMETHIONINE
Authors:Schluckebier, G, Zhong, P, Stewart, K.D, Kavanaugh, T.J, Abad-Zapatero, C.
Deposit date:1999-03-26
Release date:2000-03-29
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The 2.2 A structure of the rRNA methyltransferase ErmC' and its complexes with cofactor and cofactor analogs: implications for the reaction mechanism.
J.Mol.Biol., 289, 1999
1QAM
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BU of 1qam by Molmil
THE STRUCTURE OF THE RRNA METHYLTRANSFERASE ERMC': IMPLICATIONS FOR THE REACTION MECHANISM
Descriptor: ACETATE ION, ERMC' METHYLTRANSFERASE
Authors:Schluckebier, G, Zhong, P, Stewart, K.D, Kavanaugh, T.J, Abad-Zapatero, C.
Deposit date:1999-03-25
Release date:2000-03-29
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The 2.2 A structure of the rRNA methyltransferase ErmC' and its complexes with cofactor and cofactor analogs: implications for the reaction mechanism.
J.Mol.Biol., 289, 1999
1QAQ
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BU of 1qaq by Molmil
THE STRUCTURE OF THE RRNA METHYLTRANSFERASE ERMC': IMPLICATIONS FOR THE REACTION MECHANISM
Descriptor: ERMC' RRNA METHYLTRANSFERASE, SINEFUNGIN
Authors:Schluckebier, G, Zhong, P, Stewart, K.D, Kavanaugh, T.J, Abad-Zapatero, C.
Deposit date:1999-03-28
Release date:2000-03-29
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The 2.2 A structure of the rRNA methyltransferase ErmC' and its complexes with cofactor and cofactor analogs: implications for the reaction mechanism.
J.Mol.Biol., 289, 1999
3ZU1
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BU of 3zu1 by Molmil
Structure of LysB29(Nepsilon omega-carboxyheptadecanoyl) des(B30) Human Insulin
Descriptor: CHLORIDE ION, INSULIN A CHAIN, INSULIN B CHAIN, ...
Authors:Schluckebier, G, Whittingham, J.
Deposit date:2011-07-13
Release date:2011-08-03
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure of Lysb29(Nepsilon Omega-Carboxyheptadecanoyl) Des(B30) Human Insulin
To be Published
8CN9
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BU of 8cn9 by Molmil
Factor VII binding Fab of the bispecific antibody HMB-001 in complex with Factor VII
Descriptor: CALCIUM ION, CESIUM ION, Coagulation factor VII, ...
Authors:Schluckebier, G, Johansson, E.
Deposit date:2023-02-22
Release date:2023-12-27
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:A bispecific antibody approach for the potential prophylactic treatment of inherited bleeding disorders
Nat Cardiovasc Res, 2023
1TRP
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BU of 1trp by Molmil
X-RAY CRYSTALLOGRAPHIC AND CALORIMERIC STUDIES OF THE EFFECTS OF THE MUTATION TRP 59 TYR IN RIBONUCLEASE T1
Descriptor: CALCIUM ION, GUANOSINE-2'-MONOPHOSPHATE, RIBONUCLEASE T1 ISOZYME
Authors:Schluckebier, G, Saenger, W.
Deposit date:1993-07-06
Release date:1994-04-30
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:X-ray crystallographic and calorimetric studies of the effects of the mutation Trp59-->Tyr in ribonuclease T1.
Eur.J.Biochem., 220, 1994
8PJC
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BU of 8pjc by Molmil
Crystal structure of human insulin desB30 precursor with an Alanine-Alanine-Lysine C-peptide in dimer (T2) conformation
Descriptor: Insulin
Authors:Schluckebier, G, Johansson, E.
Deposit date:2023-06-23
Release date:2023-11-08
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Molecular engineering of insulin for recombinant expression in yeast.
Trends Biotechnol, 2023
8PJH
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BU of 8pjh by Molmil
Crystal structure of human insulin desB30 precursor with an Aspartate-Glycine-Lysine C-peptide in dimer (T2) conformation
Descriptor: Insulin
Authors:Schluckebier, G, Johansson, E.
Deposit date:2023-06-23
Release date:2023-11-08
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Molecular engineering of insulin for recombinant expression in yeast.
Trends Biotechnol, 2023
6GNQ
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BU of 6gnq by Molmil
Monoclinic crystalline form of human insulin, complexed with meta-cresol
Descriptor: 1,2-ETHANEDIOL, Insulin, M-CRESOL, ...
Authors:Margiolaki, I, Karavassili, F, Valmas, A, Dimarogona, M, Giannopoulou, A.E, Fili, S, Schluckebier, G, Norrman, M, Beckers, D, Fitch, A.N.
Deposit date:2018-05-31
Release date:2019-06-12
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Monoclinic crystalline form of human insulin, complexed with meta-cresol
To Be Published
4IDW
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BU of 4idw by Molmil
Polycrystalline T6 Bovine Insulin: Anisotropic Lattice Evolution and Novel Structure Refinement Strategy
Descriptor: Insulin A chain, Insulin B chain, ZINC ION
Authors:Margiolaki, I, Giannopoulou, A.E, Wright, J.P, Knight, L, Norrman, M, Schluckebier, G, Fitch, A, Von Dreele, R.B.
Deposit date:2012-12-13
Release date:2013-06-05
Method:POWDER DIFFRACTION
Cite:High-resolution powder X-ray data reveal the T6 hexameric form of bovine insulin
Acta Crystallogr.,Sect.D, 69, 2013
5E94
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BU of 5e94 by Molmil
Antibody-bound Glucagon-like Peptide-1 receptor extracellular domain
Descriptor: Antibody Fab fragment heavy chain, Antibody Fab fragment light chain, Glucagon-like peptide 1 receptor
Authors:Soroka, V, Schluckebier, G, Reedtz-Runge, S.
Deposit date:2015-10-14
Release date:2016-08-24
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural insight into antibody-mediated antagonism of the Glucagon-like peptide-1 Receptor.
Sci Rep, 6, 2016
2ERC
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BU of 2erc by Molmil
CRYSTAL STRUCTURE OF ERMC' A RRNA-METHYL TRANSFERASE
Descriptor: RRNA METHYL TRANSFERASE
Authors:Bussiere, D.E, Muchmore, S.W, Dealwis, C.G, Schluckebier, G, Abad-Zapatero, C.
Deposit date:1998-03-13
Release date:1999-03-23
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3.03 Å)
Cite:Crystal structure of ErmC', an rRNA methyltransferase which mediates antibiotic resistance in bacteria.
Biochemistry, 37, 1998
8CHE
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BU of 8che by Molmil
TLT-1 binding Fab of the bispecific antibody HMB-001 in complex with the TLT-1 stalk peptide
Descriptor: Fab heavy chain, Fab light chain, Trem-like transcript 1 protein
Authors:Johansson, E, Schluckebier, G.
Deposit date:2023-02-07
Release date:2023-12-27
Method:X-RAY DIFFRACTION (1.49 Å)
Cite:HMB-001: A Novel Bispecific Antibody Accumulating and Targeting Endogenous FVIIa to Activated Platelets for Subcutaneous Prophylaxis in Multiple Bleeding Disorders Including Glanzmann Thrombasthenia.
To Be Published
6FF3
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BU of 6ff3 by Molmil
Crystal structure of Drosophila neural ectodermal development factor Imp-L1 with Human IGF-I
Descriptor: Insulin-like growth factor I, Neural/ectodermal development factor IMP-L2
Authors:Brzozowski, A.M, Kulahin, N, Kristensen, O, Schluckebier, G, Meyts, P.D, Viola, C.M.
Deposit date:2018-01-03
Release date:2018-09-26
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.57 Å)
Cite:Structures of insect Imp-L2 suggest an alternative strategy for regulating the bioavailability of insulin-like hormones.
Nat Commun, 9, 2018
6FEY
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BU of 6fey by Molmil
Crystal structure of Drosophila neural ectodermal development factor Imp-L2 with Drosophila DILP5 insulin
Descriptor: Neural/ectodermal development factor IMP-L2, Probable insulin-like peptide 5
Authors:Brzozowski, A.M, Kulahin, N, Kristensen, O, Schluckebier, G, Meyts, P.D.
Deposit date:2018-01-03
Release date:2018-09-26
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.48 Å)
Cite:Structures of insect Imp-L2 suggest an alternative strategy for regulating the bioavailability of insulin-like hormones.
Nat Commun, 9, 2018
8PI5
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BU of 8pi5 by Molmil
Crystal structure of human insulin desB30 precursor with an Alanine-Methionine-Lysine C-peptide in hexamer (T3R3) conformation
Descriptor: CHLORIDE ION, Insulin B chain,Insulin A chain, RESORCINOL, ...
Authors:Johansson, E, Schluckebier, G.
Deposit date:2023-06-21
Release date:2023-11-08
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:Molecular engineering of insulin for recombinant expression in yeast.
Trends Biotechnol, 2023
8PI6
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BU of 8pi6 by Molmil
Crystal structure of the monomeric zinc free human insulin A22K, B3E, B26E, B29R, desB30 precursor with a Ser-Glu-Asp-Trp-Trp-Arg C-peptide and a Glu-Glu-Gly-Glu-Pro-Arg N-terminal extension
Descriptor: Insulin B chain,Insulin A chain
Authors:Johansson, E, Schluckebier, G.
Deposit date:2023-06-21
Release date:2023-11-08
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Molecular engineering of insulin for recombinant expression in yeast.
Trends Biotechnol, 2023
8PI4
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BU of 8pi4 by Molmil
Crystal structure of human insulin desB30 precursor with an Alanine-Methionine-Lysine C-peptide in dimer (T2) conformation
Descriptor: Insulin B chain,Insulin A chain
Authors:Johansson, E, Schluckebier, G.
Deposit date:2023-06-21
Release date:2023-11-08
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Molecular engineering of insulin for recombinant expression in yeast.
Trends Biotechnol, 2023
7PG4
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BU of 7pg4 by Molmil
Low resolution Cryo-EM structure of the full-length insulin receptor bound to 2 insulin, conf 3
Descriptor: Insulin, Isoform Short of Insulin receptor
Authors:Nielsen, J.A, Slaaby, R, Boesen, T, Hummelshoj, T, Brandt, J, Schluckebier, G, Nissen, P.
Deposit date:2021-08-12
Release date:2022-02-02
Last modified:2022-02-16
Method:ELECTRON MICROSCOPY (9.1 Å)
Cite:Structural Investigations of Full-Length Insulin Receptor Dynamics and Signalling.
J.Mol.Biol., 434, 2022
7PG0
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BU of 7pg0 by Molmil
Low resolution Cryo-EM structure of full-length insulin receptor bound to 3 insulin with visible ddm micelle, conf 1
Descriptor: Insulin, Isoform Short of Insulin receptor
Authors:Nielsen, J.A, Slaaby, R, Boesen, T, Hummelshoj, T, Brandt, J, Schluckebier, G, Nissen, P.
Deposit date:2021-08-12
Release date:2022-02-02
Last modified:2022-02-16
Method:ELECTRON MICROSCOPY (7.6 Å)
Cite:Structural Investigations of Full-Length Insulin Receptor Dynamics and Signalling.
J.Mol.Biol., 434, 2022
7PG2
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BU of 7pg2 by Molmil
Low resolution Cryo-EM structure of full-length insulin receptor bound to 3 insulin, conf 1
Descriptor: Insulin, Isoform Short of Insulin receptor
Authors:Nielsen, J.A, Slaaby, R, Boesen, T, Hummelshoj, T, Brandt, J, Schluckebier, G, Nissen, P.
Deposit date:2021-08-12
Release date:2022-02-02
Last modified:2022-02-16
Method:ELECTRON MICROSCOPY (6.7 Å)
Cite:Structural Investigations of Full-Length Insulin Receptor Dynamics and Signalling.
J.Mol.Biol., 434, 2022

 

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