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1AJW
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BU of 1ajw by Molmil
STRUCTURE OF RHOGDI: A C-TERMINAL BINDING DOMAIN TARGETS AN N-TERMINAL INHIBITORY PEPTIDE TO GTPASES, NMR, 20 STRUCTURES
Descriptor: RHOGDI
Authors:Rosen, M.K, Gosser, Y.Q.
Deposit date:1997-05-11
Release date:1997-11-19
Last modified:2022-02-16
Method:SOLUTION NMR
Cite:C-terminal binding domain of Rho GDP-dissociation inhibitor directs N-terminal inhibitory peptide to GTPases.
Nature, 387, 1997
1GDF
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BU of 1gdf by Molmil
STRUCTURE OF RHOGDI: A C-TERMINAL BINDING DOMAIN TARGETS AN N-TERMINAL INHIBITORY PEPTIDE TO GTPASES, NMR, MINIMIZED AVERAGE STRUCTURE
Descriptor: RHOGDI
Authors:Rosen, M.K, Gosser, Y.Q.
Deposit date:1997-05-11
Release date:1997-11-19
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:C-terminal binding domain of Rho GDP-dissociation inhibitor directs N-terminal inhibitory peptide to GTPases.
Nature, 387, 1997
3KY9
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BU of 3ky9 by Molmil
Autoinhibited Vav1
Descriptor: Proto-oncogene vav, ZINC ION
Authors:Tomchick, D.R, Rosen, M.K, Machius, M, Yu, B.
Deposit date:2009-12-04
Release date:2010-02-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.731 Å)
Cite:Structural and Energetic Mechanisms of Cooperative Autoinhibition and Activation of Vav1
Cell(Cambridge,Mass.), 140, 2010
1BY1
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BU of 1by1 by Molmil
DBL homology domain from beta-PIX
Descriptor: PROTEIN (PIX)
Authors:Aghazadeh, B, Zhu, K, Kubiseski, T.J, Liu, G.A, Pawson, T, Zheng, Y, Rosen, M.K.
Deposit date:1998-10-22
Release date:1999-10-24
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Structure and Mutagenesis of the Dbl Homology Domain
Nat.Struct.Biol., 5, 1998
1FKT
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BU of 1fkt by Molmil
SOLUTION STRUCTURE OF FKBP, A ROTAMASE ENZYME AND RECEPTOR FOR FK506 AND RAPAMYCIN
Descriptor: FK506 AND RAPAMYCIN-BINDING PROTEIN
Authors:Michnick, S.W, Rosen, M.K, Wandless, T.J, Karplus, M, Schreiber, S.L.
Deposit date:1992-03-05
Release date:1994-01-31
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Solution structure of FKBP, a rotamase enzyme and receptor for FK506 and rapamycin.
Science, 252, 1991
1FKR
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BU of 1fkr by Molmil
SOLUTION STRUCTURE OF FKBP, A ROTAMASE ENZYME AND RECEPTOR FOR FK506 AND RAPAMYCIN
Descriptor: FK506 AND RAPAMYCIN-BINDING PROTEIN
Authors:Michnick, S.W, Rosen, M.K, Wandless, T.J, Karplus, M, Schreiber, S.L.
Deposit date:1992-03-05
Release date:1994-01-31
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Solution structure of FKBP, a rotamase enzyme and receptor for FK506 and rapamycin.
Science, 252, 1991
1FKS
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BU of 1fks by Molmil
SOLUTION STRUCTURE OF FKBP, A ROTAMASE ENZYME AND RECEPTOR FOR FK506 AND RAPAMYCIN
Descriptor: FK506 AND RAPAMYCIN-BINDING PROTEIN
Authors:Michnick, S.W, Rosen, M.K, Wandless, T.J, Karplus, M, Schreiber, S.L.
Deposit date:1992-03-05
Release date:1994-01-31
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Solution structure of FKBP, a rotamase enzyme and receptor for FK506 and rapamycin.
Science, 252, 1991
1SRM
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BU of 1srm by Molmil
1H AND 15N ASSIGNMENTS AND SECONDARY STRUCTURE OF THE SRC SH3 DOMAIN
Descriptor: SRC TYROSINE KINASE SH3 DOMAIN
Authors:Yu, H, Rosen, M.K, Shin, T.B, Seidel-Dugan, C, Brugge, J.S, Schreiber, S.L.
Deposit date:1994-03-07
Release date:1994-05-31
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:1H and 15N assignments and secondary structure of the Src SH3 domain.
FEBS Lett., 324, 1993
1SRL
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BU of 1srl by Molmil
1H AND 15N ASSIGNMENTS AND SECONDARY STRUCTURE OF THE SRC SH3 DOMAIN
Descriptor: SRC TYROSINE KINASE SH3 DOMAIN
Authors:Yu, H, Rosen, M.K, Shin, T.B, Seidel-Dugan, C, Brugge, J.S, Schreiber, S.L.
Deposit date:1994-03-07
Release date:1994-05-31
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:1H and 15N assignments and secondary structure of the Src SH3 domain.
FEBS Lett., 324, 1993
3OBV
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BU of 3obv by Molmil
Autoinhibited Formin mDia1 Structure
Descriptor: Protein diaphanous homolog 1, beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose
Authors:Tomchick, D.R, Rosen, M.K, Otomo, T.
Deposit date:2010-08-09
Release date:2010-11-24
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Crystal structure of the Formin mDia1 in autoinhibited conformation.
Plos One, 5, 2010
3P8C
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BU of 3p8c by Molmil
Structure and Control of the Actin Regulatory WAVE Complex
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Abl interactor 2, CHLORIDE ION, ...
Authors:Chen, Z, Borek, D, Padrick, S.B, Gomez, T.S, Metlagel, Z, Ismail, A.M, Umetani, J, Billadeau, D.D, Otwinowski, Z, Rosen, M.K.
Deposit date:2010-10-13
Release date:2010-12-01
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Structure and control of the actin regulatory WAVE complex.
Nature, 468, 2010
1ZZV
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BU of 1zzv by Molmil
Solution NMR Structure of the Periplasmic Signaling Domain of the Outer Membrane Iron Transporter FecA from Escherichia coli.
Descriptor: Iron(III) dicitrate transport protein fecA
Authors:Ferguson, A.D, Amezcua, C.A, Chelliah, Y, Rosen, M.K, Deisenhofer, J.
Deposit date:2005-06-14
Release date:2006-09-26
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:Signal transduction pathway of TonB-dependent transporters.
Proc.Natl.Acad.Sci.Usa, 2, 2006
2A02
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BU of 2a02 by Molmil
Solution NMR Structure of the Periplasmic Signaling Domain of the Outer Membrane Iron Transporter PupA from Pseudomonas putida.
Descriptor: Ferric-pseudobactin 358 receptor
Authors:Ferguson, A.D, Amezcua, C.A, Chelliah, Y, Rosen, M.K, Deisenhofer, J.
Deposit date:2005-06-15
Release date:2006-09-26
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:Signal transduction pathway of TonB-dependent transporters.
Proc.Natl.Acad.Sci.Usa, 2, 2006
2BNX
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BU of 2bnx by Molmil
Crystal structure of the dimeric regulatory domain of mouse diaphaneous-related formin (DRF), mDia1
Descriptor: CHLORIDE ION, DIAPHANOUS PROTEIN HOMOLOG 1
Authors:Otomo, T, Otomo, C, Tomchick, D.R, Machius, M, Rosen, M.K.
Deposit date:2005-04-05
Release date:2005-06-13
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural Basis of Rho Gtpase-Mediated Activation of the Formin Mdia1
Mol.Cell, 18, 2005
2K42
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BU of 2k42 by Molmil
Solution Structure of the GTPase Binding Domain of WASP in Complex with EspFU, an EHEC Effector
Descriptor: ESPFU, Wiskott-Aldrich syndrome protein
Authors:Cheng, H.-C, Skehan, B.M, Campellone, K.G, Leong, J.M, Rosen, M.K.
Deposit date:2008-05-27
Release date:2008-07-22
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:Structural mechanism of WASP activation by the enterohaemorrhagic E. coli effector EspF(U).
Nature, 454, 2008
3SEO
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BU of 3seo by Molmil
Crystal structure of VopL C terminal domain
Descriptor: CHLORIDE ION, VopL C terminal domain protein
Authors:Yu, B, Rosen, M.K, Tomchick, D.R.
Deposit date:2011-06-10
Release date:2011-08-31
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.305 Å)
Cite:Mechanism of actin filament nucleation by the bacterial effector VopL.
Nat.Struct.Mol.Biol., 18, 2011
4M63
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BU of 4m63 by Molmil
Crystal Structure of a Filament-Like Actin Trimer Bound to the Bacterial Effector VopL
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Actin-5C, CALCIUM ION, ...
Authors:Tomchick, D.R, Zahm, J.A, Rosen, M.K.
Deposit date:2013-08-08
Release date:2013-10-23
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.748 Å)
Cite:The Bacterial Effector VopL Organizes Actin into Filament-like Structures.
Cell(Cambridge,Mass.), 155, 2013
1CEE
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BU of 1cee by Molmil
SOLUTION STRUCTURE OF CDC42 IN COMPLEX WITH THE GTPASE BINDING DOMAIN OF WASP
Descriptor: GTP-BINDING RHO-LIKE PROTEIN, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, ...
Authors:Abdul-Manan, N, Aghazadeh, B, Liu, G.A, Majumdar, A, Ouerfelli, O, Rosen, M.K.
Deposit date:1999-03-08
Release date:1999-06-30
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Structure of Cdc42 in complex with the GTPase-binding domain of the 'Wiskott-Aldrich syndrome' protein.
Nature, 399, 1999
1EJ5
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BU of 1ej5 by Molmil
SOLUTION STRUCTURE OF THE AUTOINHIBITED CONFORMATION OF WASP
Descriptor: WISKOTT-ALDRICH SYNDROME PROTEIN
Authors:Kim, A.S, Kakalis, L.T, Abdul-Manan, N, Liu, G.A, Rosen, M.K.
Deposit date:2000-02-29
Release date:2000-04-05
Last modified:2022-02-16
Method:SOLUTION NMR
Cite:Autoinhibition and activation mechanisms of the Wiskott-Aldrich syndrome protein.
Nature, 404, 2000
1F5X
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BU of 1f5x by Molmil
NMR STRUCTURE OF THE Y174 AUTOINHIBITED DBL HOMOLOGY DOMAIN
Descriptor: RHO-GEF VAV
Authors:Aghazadeh, B, Rosen, M.K, Lowry, W.E, Huang, X.Y.
Deposit date:2000-06-18
Release date:2000-09-15
Last modified:2022-02-16
Method:SOLUTION NMR
Cite:Structural basis for relief of autoinhibition of the Dbl homology domain of proto-oncogene Vav by tyrosine phosphorylation.
Cell(Cambridge,Mass.), 102, 2000
1T84
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BU of 1t84 by Molmil
Solution structure of the Wiskott-Aldrich Syndrome Protein (WASP) autoinhibited core domain complexed with (S)-wiskostatin, a small molecule inhibitor
Descriptor: (2S)-1-(3,6-DIBROMO-9H-CARBAZOL-9-YL)-3-(DIMETHYLAMINO)PROPAN-2-OL, Wiskott-Aldrich syndrome protein
Authors:Peterson, J.R, Bickford, L.C, Morgan, D, Kim, A.S, Ouerfelli, O, Kirschner, M.W, Rosen, M.K.
Deposit date:2004-05-11
Release date:2004-07-13
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:Chemical inhibition of N-WASP by stabilization of a native autoinhibited conformation.
Nat.Struct.Mol.Biol., 11, 2004
1Y64
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BU of 1y64 by Molmil
Bni1p Formin Homology 2 Domain complexed with ATP-actin
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Otomo, T, Tomchick, D.R, Otomo, C, Panchal, S.C, Machius, M, Rosen, M.K.
Deposit date:2004-12-03
Release date:2005-01-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Structural basis of actin filament nucleation and processive capping by a formin homology 2 domain
Nature, 433, 2005
1NF3
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BU of 1nf3 by Molmil
Structure of Cdc42 in a complex with the GTPase-binding domain of the cell polarity protein, Par6
Descriptor: G25K GTP-binding protein, placental isoform, MAGNESIUM ION, ...
Authors:Garrard, S.M, Capaldo, C.T, Gao, L, Rosen, M.K, Macara, I.G, Tomchick, D.R.
Deposit date:2002-12-12
Release date:2003-03-04
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure of Cdc42 in a complex with the GTPase-binding domain of the cell polarity protein, Par6
Embo J., 22, 2003
1OMB
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BU of 1omb by Molmil
SEQUENTIAL ASSIGNMENT AND STRUCTURE DETERMINATION OF SPIDER TOXIN OMEGA-AGA-IVB
Descriptor: OMEGA-AGA-IVB
Authors:Yu, H, Rosen, M.K, Schreiber, S.L.
Deposit date:1993-09-09
Release date:1993-10-31
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Sequential assignment and structure determination of spider toxin omega-Aga-IVB.
Biochemistry, 32, 1993
1OMA
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BU of 1oma by Molmil
SEQUENTIAL ASSIGNMENT AND STRUCTURE DETERMINATION OF SPIDER TOXIN OMEGA-AGA-IVB
Descriptor: OMEGA-AGA-IVB
Authors:Yu, H, Rosen, M.K, Schreiber, S.L.
Deposit date:1993-09-09
Release date:1993-10-31
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Sequential assignment and structure determination of spider toxin omega-Aga-IVB.
Biochemistry, 32, 1993

 

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