Author results

2P6B
  • Download 2p6b
  • View 2p6b
Molmil generated image of 2p6b
CRYSTAL STRUCTURE OF HUMAN CALCINEURIN IN COMPLEX WITH PVIVIT PEPTIDE
Descriptor:PVIVIT 14-mer Peptide, Calmodulin-dependent calcineurin A subunit alpha isoform, Calcineurin subunit B isoform 1, ...
Authors:Li, H., Zhang, L., Rao, A., Harrison, S.C., Hogan, P.G.
Deposit date:2007-03-16
Release date:2007-06-05
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of calcineurin in complex with PVIVIT peptide: Portrait of a low-affinity signalling interaction
J.Mol.Biol., 369, 2007
1PZU
  • Download 1pzu
  • View 1pzu
Molmil generated image of 1pzu
AN ASYMMETRIC NFAT1-RHR HOMODIMER ON A PSEUDO-PALINDROMIC, KAPPA-B SITE
Descriptor:5'-D(*TP*TP*GP*AP*GP*GP*AP*AP*TP*TP*TP*CP*CP*A)-3', 5'-D(*AP*AP*TP*GP*GP*AP*AP*AP*TP*TP*CP*CP*TP*C)-3', Nuclear factor of activated T-cells, ...
Authors:Jin, L., Sliz, P., Chen, L., Macian, F., Rao, A., Hogan, P.G., Harrison, S.C.
Deposit date:2003-07-14
Release date:2003-09-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:An asymmetric NFAT1 dimer on a pseudo-palindromic KB-like DNA site
Nat.Struct.Biol., 10, 2003
2AS5
  • Download 2as5
  • View 2as5
Molmil generated image of 2as5
STRUCTURE OF THE DNA BINDING DOMAINS OF NFAT AND FOXP2 BOUND SPECIFICALLY TO DNA.
Descriptor:5'-D(TP*TP*AP*GP*GP*AP*AP*AP*AP*TP*TP*TP*GP*TP*TP*TP*CP*AP*TP*AP*GP*)-3', 5'-D(AP*AP*CP*TP*AP*TP*GP*AP*AP*AP*CP*AP*AP*AP*TP*TP*TP*TP*CP*CP*TP*)-3', Nuclear factor of activated T-cells, ...
Authors:Wu, Y., Stroud, J.C., Borde, M., Bates, D.L., Guo, L., Han, A., Rao, A., Chen, L.
Deposit date:2005-08-22
Release date:2006-08-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:FOXP3 Controls Regulatory T Cell Function through Cooperation with NFAT.
Cell(Cambridge,Mass.), 126, 2006
1A02
  • Download 1a02
  • View 1a02
Molmil generated image of 1a02
STRUCTURE OF THE DNA BINDING DOMAINS OF NFAT, FOS AND JUN BOUND TO DNA
Descriptor:DNA (5'-D(*DTP*DTP*DGP*DGP*DAP*DAP*DAP*DAP*DTP*DTP*DTP*DGP*DTP*DTP*DTP*DCP*DAP*DTP*DAP*DG)-3'), DNA (5'-D(*DAP*DAP*DCP*DTP*DAP*DTP*DGP*DAP*DAP*DAP*DCP*DAP*DAP*DAP*DTP*DTP*DTP*DTP*DCP*DC)-3'), NUCLEAR FACTOR OF ACTIVATED T CELLS, ...
Authors:Chen, L., Glover, J.N.M., Hogan, P.G., Rao, A., Harrison, S.C.
Deposit date:1997-12-08
Release date:1998-05-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of the DNA-binding domains from NFAT, Fos and Jun bound specifically to DNA.
Nature, 392, 1998
1IMH
  • Download 1imh
  • View 1imh
Molmil generated image of 1imh
TONEBP/DNA COMPLEX
Descriptor:5'-D(*TP*TP*GP*CP*TP*GP*GP*AP*AP*AP*AP*AP*TP*AP*G)-3', 5'-D(*AP*AP*CP*TP*AP*TP*TP*TP*TP*TP*CP*CP*AP*GP*C)-3', NUCLEAR FACTOR OF ACTIVATED T CELLS 5
Authors:Stroud, J.C., Lopez-Rodriguez, C., Rao, A., Chen, L.
Deposit date:2001-05-10
Release date:2002-02-01
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (2.86 Å)
Cite:Structure of a TonEBP-DNA complex reveals DNA encircled by a transcription factor.
Nat.Struct.Biol., 9, 2002
3QRF
  • Download 3qrf
  • View 3qrf
Molmil generated image of 3qrf
STRUCTURE OF A DOMAIN-SWAPPED FOXP3 DIMER
Descriptor:Nuclear factor of activated T-cells, cytoplasmic 2, Forkhead box protein P3, ...
Authors:Bandukwala, H.S., Wu, Y., Feurer, M., Chen, Y., Barbosa, B., Ghosh, S., Stroud, J.C., Benoist, C., Mathis, D., Rao, A., Chen, L.
Deposit date:2011-02-17
Release date:2011-04-20
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of a Domain-Swapped FOXP3 Dimer on DNA and Its Function in Regulatory T Cells.
Immunity, 34, 2011
5KO9
  • Download 5ko9
  • View 5ko9
Molmil generated image of 5ko9
CRYSTAL STRUCTURE OF THE SRAP DOMAIN OF HUMAN HMCES PROTEIN
Descriptor:Embryonic stem cell-specific 5-hydroxymethylcytosine-binding protein, UNKNOWN ATOM OR ION
Authors:Halabelian, L., Li, Y., Bountra, C., Edwards, A.M., Arrowsmith, C.H., Structural Genomics Consortium (SGC)
Deposit date:2016-06-29
Release date:2016-08-24
Last modified:2019-06-26
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural Basis of HMCES Interactions with Abasic DNA and Multivalent Substrate Recognition
Nat.Struct.Mol.Biol., 2019
6OE7
  • Download 6oe7
  • View 6oe7
Molmil generated image of 6oe7
CRYSTAL STRUCTURE OF HMCES CROSS-LINKED TO DNA ABASIC SITE
Descriptor:Embryonic stem cell-specific 5-hydroxymethylcytosine-binding protein, DNA (5'-D(*GP*TP*CP*TP*GP*G)-3'), DNA (5'-D(*CP*CP*AP*GP*AP*CP*GP*TP*(DRZ)P*GP*TP*T)-3'), ...
Authors:Halabelian, L., Li, Y., Zeng, H., Bountra, C., Edwards, A.M., Arrowsmith, C.H., Structural Genomics Consortium (SGC)
Deposit date:2019-03-27
Release date:2019-04-24
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis of HMCES interactions with abasic DNA and multivalent substrate recognition.
Nat.Struct.Mol.Biol., 26, 2019
6OEA
  • Download 6oea
  • View 6oea
Molmil generated image of 6oea
CRYSTAL STRUCTURE OF HMCES SRAP DOMAIN IN COMPLEX WITH LONGER 3' OVERHANG DNA
Descriptor:Embryonic stem cell-specific 5-hydroxymethylcytosine-binding protein, DNA (5'-D(*CP*CP*AP*GP*AP*CP*GP*TP*TP*GP*TP*T)-3'), DNA (5'-D(*GP*TP*CP*TP*GP*G)-3'), ...
Authors:Halabelian, L., Ravichandran, M., Li, Y., Zeng, H., Bountra, C., Edwards, A.M., Arrowsmith, C.H., Structural Genomics Consortium (SGC)
Deposit date:2019-03-27
Release date:2019-04-10
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis of HMCES interactions with abasic DNA and multivalent substrate recognition.
Nat.Struct.Mol.Biol., 26, 2019
6OEB
  • Download 6oeb
  • View 6oeb
Molmil generated image of 6oeb
CRYSTAL STRUCTURE OF HMCES SRAP DOMAIN IN COMPLEX WITH 3' OVERHANG DNA
Descriptor:Embryonic stem cell-specific 5-hydroxymethylcytosine-binding protein, DNA (5'-D(*CP*CP*AP*GP*AP*CP*GP*TP*T)-3'), DNA (5'-D(*GP*TP*CP*TP*GP*G)-3'), ...
Authors:Halabelian, L., Ravichandran, M., Li, Y., Zeng, H., Bountra, C., Edwards, A.M., Arrowsmith, C.H., Structural Genomics Consortium (SGC)
Deposit date:2019-03-27
Release date:2019-04-10
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis of HMCES interactions with abasic DNA and multivalent substrate recognition.
Nat.Struct.Mol.Biol., 26, 2019
3LL8
  • Download 3ll8
  • View 3ll8
Molmil generated image of 3ll8
CRYSTAL STRUCTURE OF CALCINEURIN IN COMPLEX WITH AKAP79 PEPTIDE
Descriptor:AKAP79 peptide, Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform, Calcineurin subunit B type 1, ...
Authors:Li, H., Hogan, P.G.
Deposit date:2010-01-28
Release date:2011-01-12
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2 Å)
Cite:Balanced interactions of calcineurin with AKAP79 regulate Ca(2+)-calcineurin-NFAT signaling.
Nat.Struct.Mol.Biol., 19, 2012