3IGC
| Smallpox virus topoisomerase-DNA transition state | Descriptor: | 5'-D(*AP*TP*TP*CP*C)-3', 5'-D(*CP*GP*GP*AP*AP*TP*AP*AP*GP*GP*GP*CP*GP*AP*CP*A)-3', 5'-D(*GP*TP*GP*TP*CP*GP*CP*CP*CP*TP*T)-3', ... | Authors: | Perry, K, Hwang, Y, Bushman, F.D, Van Duyne, G.D. | Deposit date: | 2009-07-27 | Release date: | 2010-03-02 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Insights from the Structure of a Smallpox Virus Topoisomerase-DNA Transition State Mimic. Structure, 18, 2010
|
|
2H7F
| Structure of variola topoisomerase covalently bound to DNA | Descriptor: | 5'-D(*TP*AP*AP*TP*AP*AP*GP*GP*GP*CP*GP*AP*CP*A)-3', 5'-D(*TP*TP*GP*TP*CP*GP*CP*CP*CP*TP*T)-3', DNA topoisomerase 1 | Authors: | Perry, K, Hwang, Y, Bushman, F.D, Van Duyne, G.D. | Deposit date: | 2006-06-02 | Release date: | 2006-08-15 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural basis for specificity in the poxvirus topoisomerase. Mol.Cell, 23, 2006
|
|
2H7G
| Structure of variola topoisomerase non-covalently bound to DNA | Descriptor: | 5'-D(*TP*AP*AP*TP*AP*AP*GP*GP*GP*CP*GP*AP*CP*A)-3', 5'-D(*TP*TP*GP*TP*CP*GP*CP*CP*CP*TP*TP*A)-3', DNA topoisomerase 1 | Authors: | Perry, K, Hwang, Y, Bushman, F.D, Van Duyne, G.D. | Deposit date: | 2006-06-02 | Release date: | 2006-08-15 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural basis for specificity in the poxvirus topoisomerase. Mol.Cell, 23, 2006
|
|
1MW8
| |
1MW9
| |
5JMC
| Receptor binding domain of Botulinum neurotoxin A in complex with rat SV2C | Descriptor: | Botulinum neurotoxin type A, Synaptic vesicle glycoprotein 2C | Authors: | Yao, G, Zhang, S, Mahrhold, S, Lam, K, Stern, D, Bagramyan, K, Perry, K, Kalkum, M, Rummel, A, Dong, M, Jin, R. | Deposit date: | 2016-04-28 | Release date: | 2016-06-15 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.64 Å) | Cite: | N-linked glycosylation of SV2 is required for binding and uptake of botulinum neurotoxin A. Nat.Struct.Mol.Biol., 23, 2016
|
|
5JLV
| Receptor binding domain of Botulinum neurotoxin A in complex with human glycosylated SV2C | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ... | Authors: | Yao, G, Zhang, S, Mahrhold, S, Lam, K, Stern, D, Bagramyan, K, Perry, K, Kalkum, M, Rummel, A, Dong, M, Jin, R. | Deposit date: | 2016-04-27 | Release date: | 2016-06-15 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | N-linked glycosylation of SV2 is required for binding and uptake of botulinum neurotoxin A. Nat.Struct.Mol.Biol., 23, 2016
|
|
4QD2
| Molecular basis for disruption of E-cadherin adhesion by botulinum neurotoxin A complex | Descriptor: | CALCIUM ION, Cadherin-1, Hemagglutinin component HA17, ... | Authors: | Lee, K, Zhong, X, Gu, S, Kruel, A, Dorner, M.B, Perry, K, Rummel, A, Dong, M, Jin, R. | Deposit date: | 2014-05-13 | Release date: | 2014-06-25 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Molecular basis for disruption of E-cadherin adhesion by botulinum neurotoxin A complex. Science, 344, 2014
|
|
7C0Q
| a Legionella pneumophila effector Lpg2505 | Descriptor: | GLYCEROL, effector Lpg2505 | Authors: | Chen, T.T, Han, A.D, Luo, Z.Q, McCloskey, A, Perri, K. | Deposit date: | 2020-05-01 | Release date: | 2021-02-24 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | The metaeffector MesI regulates the activity of the Legionella effector SidI through direct protein-protein interactions. Microbes Infect., 23, 2021
|
|
8UIV
| H47Q NicC with bound FAD | Descriptor: | 6-hydroxynicotinate 3-monooxygenase, FLAVIN-ADENINE DINUCLEOTIDE | Authors: | Hicks, K.A, Perry, K. | Deposit date: | 2023-10-10 | Release date: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.511 Å) | Cite: | Ligand bound structure of a 6-hydroxynicotinic acid 3-monooxygenase provides mechanistic insights. Arch.Biochem.Biophys., 752, 2024
|
|
8UIQ
| H47Q NicC with 2-mercaptopyridine ligand | Descriptor: | 2-PYRIDINETHIOL, 6-hydroxynicotinate 3-monooxygenase, FLAVIN-ADENINE DINUCLEOTIDE | Authors: | Hicks, K.A, Perry, K, Turlington, Z.R, Vaz Ferreira de Macedo, S. | Deposit date: | 2023-10-10 | Release date: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.17 Å) | Cite: | Ligand bound structure of a 6-hydroxynicotinic acid 3-monooxygenase provides mechanistic insights. Arch.Biochem.Biophys., 752, 2024
|
|
4QND
| Crystal structure of a SemiSWEET | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, Chemical transport protein, ... | Authors: | Yan, X, Yuyong, T, Liang, F, Perry, K. | Deposit date: | 2014-06-17 | Release date: | 2014-09-10 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.698 Å) | Cite: | Structures of bacterial homologues of SWEET transporters in two distinct conformations. Nature, 515, 2014
|
|
4KIS
| Crystal Structure of a LSR-DNA Complex | Descriptor: | CALCIUM ION, DNA (26-MER), Putative integrase [Bacteriophage A118], ... | Authors: | Rutherford, K, Yuan, P, Perry, K, Van Duyne, G.D. | Deposit date: | 2013-05-02 | Release date: | 2013-07-10 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Attachment site recognition and regulation of directionality by the serine integrases. Nucleic Acids Res., 41, 2013
|
|
4GLI
| Crystal Structure of Human SMN YG-Dimer | Descriptor: | Maltose-binding periplasmic protein, Survival motor neuron protein chimera | Authors: | Martin, R.S, Perry, K, Van Duyne, G.D. | Deposit date: | 2012-08-14 | Release date: | 2012-10-17 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.903 Å) | Cite: | The survival motor neuron protein forms soluble glycine zipper oligomers. Structure, 20, 2012
|
|
4E1H
| Fragment of human prion protein | Descriptor: | CITRIC ACID, FE (III) ION, Major prion protein | Authors: | Apostol, M.I, Perry, K, Surewicz, W.K. | Deposit date: | 2012-03-06 | Release date: | 2013-03-06 | Last modified: | 2017-11-15 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Crystal structure of a human prion protein fragment reveals a motif for oligomer formation. J.Am.Chem.Soc., 135, 2013
|
|
7ME4
| Structure of the extracellular WNT-binding module in Drosophila Ror2/Nrk | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, PALMITOLEIC ACID, Tyrosine-protein kinase transmembrane receptor Ror2 | Authors: | Mendrola, J.M, Shi, F, Perry, K, Stayrook, S.E, Lemmon, M.A. | Deposit date: | 2021-04-06 | Release date: | 2021-10-13 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | ROR and RYK extracellular region structures suggest that receptor tyrosine kinases have distinct WNT-recognition modes. Cell Rep, 37, 2021
|
|
7ME5
| Structure of the extracellular WNT-binding module in Drl-2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Tyrosine-protein kinase transmembrane receptor DRL-2 | Authors: | Shi, F, Mendrola, J.M, Perry, K, Stayrook, S.E, Lemmon, M.A. | Deposit date: | 2021-04-06 | Release date: | 2021-10-13 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | ROR and RYK extracellular region structures suggest that receptor tyrosine kinases have distinct WNT-recognition modes. Cell Rep, 37, 2021
|
|
6EDI
| |
3IX1
| Periplasmic N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine binding protein from Bacillus halodurans | Descriptor: | N-[(4-amino-2-methylpyrimidin-5-yl)methyl]formamide, N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine binding protein | Authors: | Bale, S, Rajashankar, K.R, Perry, K, Begley, T.P, Ealick, S.E. | Deposit date: | 2009-09-03 | Release date: | 2010-10-13 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | HMP Binding Protein ThiY and HMP-P Synthase THI5 Are Structural Homologues. Biochemistry, 49, 2010
|
|
4LO3
| HA17-HA33-LacNac | Descriptor: | HA-17, HA-33, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose | Authors: | Lee, K, Gu, S, Jin, L, Le, T.T, Cheng, L.W, Strotmeier, J, Kruel, A.M, Yao, G, Perry, K, Rummel, A, Jin, R. | Deposit date: | 2013-07-12 | Release date: | 2013-10-30 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.249 Å) | Cite: | Structure of a Bimodular Botulinum Neurotoxin Complex Provides Insights into Its Oral Toxicity. Plos Pathog., 9, 2013
|
|
4LO0
| Apo HA17-HA33 | Descriptor: | HA-17, HA-33 | Authors: | Lee, K, Gu, S, Jin, L, Le, T.T, Cheng, L.W, Strotmeier, J, Kruel, A.M, Yao, G, Perry, K, Rummel, A, Jin, R. | Deposit date: | 2013-07-12 | Release date: | 2013-10-30 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.055 Å) | Cite: | Structure of a Bimodular Botulinum Neurotoxin Complex Provides Insights into Its Oral Toxicity. Plos Pathog., 9, 2013
|
|
4LO2
| HA17-HA33-Lac | Descriptor: | HA-17, HA-33, beta-D-galactopyranose-(1-4)-beta-D-glucopyranose | Authors: | Lee, K, Gu, S, Jin, L, Le, T.T, Cheng, L.W, Strotmeier, J, Kruel, A.M, Yao, G, Perry, K, Rummel, A, Jin, R. | Deposit date: | 2013-07-12 | Release date: | 2013-10-30 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.254 Å) | Cite: | Structure of a Bimodular Botulinum Neurotoxin Complex Provides Insights into Its Oral Toxicity. Plos Pathog., 9, 2013
|
|
4LO4
| Apo HA-70 | Descriptor: | CHLORIDE ION, HA-70 | Authors: | Lee, K, Gu, S, Jin, L, Le, T.T, Cheng, L.W, Strotmeier, J, Kruel, A.M, Yao, G, Perry, K, Rummel, A, Jin, R. | Deposit date: | 2013-07-12 | Release date: | 2013-10-30 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.871 Å) | Cite: | Structure of a Bimodular Botulinum Neurotoxin Complex Provides Insights into Its Oral Toxicity. Plos Pathog., 9, 2013
|
|
4LO1
| HA17-HA33-Gal | Descriptor: | HA-17, HA-33, beta-D-galactopyranose | Authors: | Lee, K, Gu, S, Jin, L, Le, T.T, Cheng, L.W, Strotmeier, J, Kruel, A.M, Yao, G, Perry, K, Rummel, A, Jin, R. | Deposit date: | 2013-07-12 | Release date: | 2013-10-30 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.254 Å) | Cite: | Structure of a Bimodular Botulinum Neurotoxin Complex Provides Insights into Its Oral Toxicity. Plos Pathog., 9, 2013
|
|
4LO5
| HA70-alpha2,3-SiaLC | Descriptor: | CHLORIDE ION, HA-70, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-alpha-D-glucopyranose | Authors: | Lee, K, Gu, S, Jin, L, Le, T.T, Cheng, L.W, Strotmeier, J, Kruel, A.M, Yao, G, Perry, K, Rummel, A, Jin, R. | Deposit date: | 2013-07-12 | Release date: | 2013-10-30 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structure of a Bimodular Botulinum Neurotoxin Complex Provides Insights into Its Oral Toxicity. Plos Pathog., 9, 2013
|
|