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3JA8
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CRYO-EM STRUCTURE OF THE MCM2-7 DOUBLE HEXAMER
Descriptor:Minichromosome Maintenance 2, Minichromosome Maintenance 3, Minichromosome Maintenance 4, ...
Authors:Li, N., Zhai, Y., Zhang, Y., Li, W., Yang, M., Lei, J., Tye, B.K., Gao, N.
Deposit date:2015-05-09
Release date:2015-08-05
Last modified:2015-08-19
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structure of the eukaryotic MCM complex at 3.8 angstrom
Nature, 524, 2015
3M1H
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CRYSTAL STRUCTURE ANALYSIS OF THE K3 CLEAVED ADHESIN DOMAIN OF LYS-GINGIPAIN (KGP) FROM PORPHYROMONAS GINGIVALIS W83
Descriptor:Lysine specific cysteine protease, CALCIUM ION, SODIUM ION
Authors:Li, N., Collyer, C.A., Hunter, N.
Deposit date:2010-03-05
Release date:2011-03-23
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.56 Å)
Cite:The modular structure of haemagglutinin/adhesin regions in gingipains of Porphyromonas gingivalis.
Mol.Microbiol., 81, 2011
3R5S
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CRYSTAL STRUCTURE OF APO-VIUP
Descriptor:Ferric vibriobactin ABC transporter, periplasmic ferric vibriobactin-binding protein
Authors:Li, N., Zhang, C., Li, B., Liu, X., Huang, Y., Xu, S., Gu, L.
Deposit date:2011-03-19
Release date:2012-02-08
Last modified:2012-05-30
Method:X-RAY DIFFRACTION (1.791 Å)
Cite:Unique iron coordination in iron-chelating molecule vibriobactin helps Vibrio cholerae evade mammalian siderocalin-mediated immune response.
J.Biol.Chem., 287, 2012
3R5T
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CRYSTAL STRUCTURE OF HOLO-VIUP
Descriptor:Ferric vibriobactin ABC transporter, periplasmic ferric vibriobactin-binding protein, (4S,5R)-N-{3-[(2,3-dihydroxybenzoyl)amino]propyl}-2-(2,3-dihydroxyphenyl)-N-[3-({[(4S,5R)-2-(2,3-dihydroxyphenyl)-5-methyl-4,5-dihydro-1,3-oxazol-4-yl]carbonyl}amino)propyl]-5-methyl-4,5-dihydro-1,3-oxazole-4-carboxamide, ...
Authors:Li, N., Zhang, C., Li, B., Liu, X., Huang, Y., Xu, S., Gu, L.
Deposit date:2011-03-19
Release date:2012-02-08
Last modified:2012-05-30
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Unique iron coordination in iron-chelating molecule vibriobactin helps Vibrio cholerae evade mammalian siderocalin-mediated immune response.
J.Biol.Chem., 287, 2012
3J3V
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ATOMIC MODEL OF THE IMMATURE 50S SUBUNIT FROM BACILLUS SUBTILIS (STATE I-A)
Descriptor:50S ribosomal protein L32, 50S ribosomal protein L34, 50S ribosomal protein L1, ...
Authors:Li, N., Guo, Q., Zhang, Y., Yuan, Y., Ma, C., Lei, J., Gao, N.
Deposit date:2013-04-28
Release date:2013-06-12
Last modified:2013-08-28
Method:ELECTRON MICROSCOPY (13.3 Å)
Cite:Cryo-EM structures of the late-stage assembly intermediates of the bacterial 50S ribosomal subunit
Nucleic Acids Res., 41, 2013
3J3W
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ATOMIC MODEL OF THE IMMATURE 50S SUBUNIT FROM BACILLUS SUBTILIS (STATE II-A)
Descriptor:ribosome RNA 23S, 50S ribosomal protein L32, 50S ribosomal protein L2, ...
Authors:Li, N., Guo, Q., Zhang, Y., Yuan, Y., Ma, C., Lei, J., Gao, N.
Deposit date:2013-04-28
Release date:2013-06-12
Last modified:2013-08-28
Method:ELECTRON MICROSCOPY (10.7 Å)
Cite:Cryo-EM structures of the late-stage assembly intermediates of the bacterial 50S ribosomal subunit
Nucleic Acids Res., 41, 2013
3KM5
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CRYSTAL STRUCTURE ANALYSIS OF THE K2 CLEAVED ADHESIN DOMAIN OF LYS-GINGIPAIN (KGP)
Descriptor:Lysine specific cysteine protease, CALCIUM ION, SULFATE ION, ...
Authors:Li, N., Collyer, C.A., Hunter, N.
Deposit date:2009-11-09
Release date:2010-03-31
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structure determination and analysis of a haemolytic gingipain adhesin domain from Porphyromonas gingivalis
Mol.Microbiol., 76, 2010
5WUA
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STRUCTURE OF A PANCREATIC ATP-SENSITIVE POTASSIUM CHANNEL
Descriptor:ATP-sensitive inward rectifier potassium channel 11,superfolder GFP, SUR1
Authors:Li, N., Wu, J.-X., Chen, L., Gao, N.
Deposit date:2016-12-16
Release date:2017-01-25
Method:ELECTRON MICROSCOPY (5.6 Å)
Cite:Structure of a Pancreatic ATP-Sensitive Potassium Channel
Cell, 168, 2017
5ZR1
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SACCHAROMYCES CEREVISIAE ORIGIN RECOGNITION COMPLEX BOUND TO A 72-BP ORIGIN DNA CONTAINING ACS AND B1 ELEMENT
Descriptor:Origin recognition complex subunit 1, Origin recognition complex subunit 2, Origin recognition complex subunit 3, ...
Authors:Li, N., Lam, W.H., Zhai, Y., Cheng, J., Cheng, E., Zhao, Y., Gao, N., Tye, B.K.
Deposit date:2018-04-21
Release date:2018-07-11
Last modified:2018-07-25
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structure of the origin recognition complex bound to DNA replication origin.
Nature, 559, 2018
1I1S
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SOLUTION STRUCTURE OF THE TRANSCRIPTIONAL ACTIVATION DOMAIN OF THE BACTERIOPHAGE T4 PROTEIN MOTA
Descriptor:MOTA
Authors:Li, N., Zhang, W., White, S.W., Kriwacki, R.W.
Deposit date:2001-02-02
Release date:2001-02-14
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of the transcriptional activation domain of the bacteriophage T4 protein, MotA.
Biochemistry, 40, 2001
1KAF
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DNA BINDING DOMAIN OF THE PHAGE T4 TRANSCRIPTION FACTOR MOTA (AA105-211)
Descriptor:Transcription regulatory protein MOTA
Authors:Li, N., Sickmier, E.A., Zhang, R., Joachimiak, A., White, S.W.
Deposit date:2001-11-01
Release date:2001-11-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The MotA transcription factor from bacteriophage T4 contains a novel DNA-binding domain: the 'double wing' motif.
Mol.Microbiol., 43, 2002
1KP6
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USTILAGO MAYDIS KILLER TOXIN KP6 ALPHA-SUBUNIT
Descriptor:PROTEIN (TOXIN), SULFATE ION
Authors:Li, N., Erman, M., Pangborn, W., Duax, W.L., Park, C.-M., Bruenn, J., Ghosh, D.
Deposit date:1999-05-28
Release date:1999-07-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of Ustilago maydis killer toxin KP6 alpha-subunit. A multimeric assembly with a central pore.
J.Biol.Chem., 274, 1999
3TLK
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CRYSTAL STRUCTURE OF HOLO FEPB
Descriptor:Ferrienterobactin-binding periplasmic protein, FE (III) ION, N,N',N''-[(3S,7S,11S)-2,6,10-trioxo-1,5,9-trioxacyclododecane-3,7,11-triyl]tris(2,3-dihydroxybenzamide), ...
Authors:Li, N., Gu, L.
Deposit date:2011-08-30
Release date:2013-01-16
Method:X-RAY DIFFRACTION (1.853 Å)
Cite:Crystal structure of holo FepB
To be Published
6IFE
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A GLYCOSIDE HYDROLASE FAMILY 43 BETA-XYLOSIDASE
Descriptor:Beta-xylosidase, GLYCEROL
Authors:Li, N., Liu, Y., Zhang, R., Zhou, J.P., Huang, Z.X.
Deposit date:2018-09-20
Release date:2019-03-13
Method:X-RAY DIFFRACTION (1.804 Å)
Cite:A Glycoside Hydrolase Family 43 beta-Xylosidase
To Be Published
1M53
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CRYSTAL STRUCTURE OF ISOMALTULOSE SYNTHASE (PALI) FROM KLEBSIELLA SP. LX3
Descriptor:Isomaltulose Synthase
Authors:Li, N., Swaminathan, K.
Deposit date:2002-07-08
Release date:2003-07-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Isomaltulose synthase (PalI) of Klebsiella sp. LX3. Crystal structure and implication of mechanism
J.Biol.Chem., 278, 2003
4GX9
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CRYSTAL STRUCTURE OF A DNA POLYMERASE III ALPHA-EPSILON CHIMERA
Descriptor:DNA polymerase III subunit epsilon,DNA polymerase III subunit alpha
Authors:Li, N., Horan, N., Xu, Z.-Q., Jacques, D., Dixon, N.E., Oakley, A.J.
Deposit date:2012-09-04
Release date:2013-04-03
Last modified:2017-06-21
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Proofreading exonuclease on a tether: the complex between the E. coli DNA polymerase III subunits alpha, {varepsilon}, theta and beta reveals a highly flexible arrangement of the proofreading domain
Nucleic Acids Res., 41, 2013
3JAC
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CRYO-EM STUDY OF A CHANNEL
Descriptor:Piezo-type mechanosensitive ion channel component 1
Authors:Ge, J., Li, W., Zhao, Q., Li, N., Xiao, B., Gao, N., Yang, M.
Deposit date:2015-06-05
Release date:2015-09-23
Last modified:2015-11-25
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Architecture of the mammalian mechanosensitive Piezo1 channel
Nature, 527, 2015
3J8G
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ELECTRON CRYO-MICROSCOPY STRUCTURE OF ENGA BOUND WITH THE 50S RIBOSOMAL SUBUNIT
Descriptor:5S rRNA, 23S rRNA, 50S ribosomal protein L28, ...
Authors:Zhang, X., Yan, K., Zhang, Y., Li, N., Ma, C., Li, Z., Zhang, Y., Feng, B., Liu, J., Sun, Y., Xu, Y., Lei, J., Gao, N.
Deposit date:2014-10-24
Release date:2014-11-26
Method:ELECTRON MICROSCOPY (5 Å)
Cite:Structural insights into the function of a unique tandem GTPase EngA in bacterial ribosome assembly
Nucleic Acids Res., 2014
5ADY
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CRYO-EM STRUCTURES OF THE 50S RIBOSOME SUBUNIT BOUND WITH HFLX
Descriptor:50S RIBOSOMAL PROTEIN L32, 50S RIBOSOMAL PROTEIN L33, 50S RIBOSOMAL PROTEIN L34, ...
Authors:Zhang, Y., Mandava, C.S., Cao, W., Li, X., Zhang, D., Li, N., Zhang, Y., Zhang, X., Qin, Y., Mi, K., Lei, J., Sanyal, S., Gao, N.
Deposit date:2015-08-25
Release date:2015-10-14
Last modified:2018-10-24
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Hflx is a Ribosome Splitting Factor Rescuing Stalled Ribosomes Under Stress Conditions
Nat.Struct.Mol.Biol., 22, 2015
5H4P
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STRUCTURAL SNAPSHOT OF CYTOPLASMIC PRE-60S RIBOSOMAL PARTICLES BOUND WITH NMD3, LSG1, TIF6 AND REH1
Descriptor:25S ribosomal RNA, 5S ribosomal RNA, 5.8S ribosomal RNA, ...
Authors:Ma, C., Wu, S., Li, N., Chen, Y., Yan, K., Li, Z., Zheng, L., Lei, J., Woolford, J.L., Gao, N.
Deposit date:2016-11-01
Release date:2017-01-25
Last modified:2017-06-14
Method:ELECTRON MICROSCOPY (3.07 Å)
Cite:Structural snapshot of cytoplasmic pre-60S ribosomal particles bound by Nmd3, Lsg1, Tif6 and Reh1
Nat. Struct. Mol. Biol., 24, 2017
3PFT
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CRYSTAL STRUCTURE OF UNTAGGED C54A MUTANT FLAVIN REDUCTASE (DSZD) IN COMPLEX WITH FMN FROM MYCOBACTERIUM GOODII
Descriptor:Flavin reductase, FLAVIN MONONUCLEOTIDE
Authors:Li, Q., Xu, P., Ma, C., Gu, L., Liu, X., Zhang, C., Li, N., Su, J., Li, B., Liu, S.
Deposit date:2010-10-29
Release date:2011-11-02
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.601 Å)
Cite:The flavin reductase DSZD from a desulfurizing mycobacterium goodii strain: systemic manipulation and investigation based on the crystal structure
To be Published
5C1U
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CRYSTAL STRUCTURE OF EV71 3C PROTEINASE IN COMPLEX WITH COMPOUND XB
Descriptor:3C proteinase, Nalpha-{(2E)-3-[4-(dimethylamino)phenyl]prop-2-enoyl}-N-{(2S)-1-oxo-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-L-phenylalaninamide
Authors:Zhang, L., Huang, G., Cai, Q., Zhao, C., Ren, H., Li, P., Li, N., Chen, S., Li, J., Lin, T.
Deposit date:2015-06-15
Release date:2016-06-01
Last modified:2016-10-26
Method:X-RAY DIFFRACTION (1.49 Å)
Cite:Optimize the interactions at S4 with efficient inhibitors targeting 3C proteinase from enterovirus 71
J.Mol.Recognit., 29, 2016
5C1X
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CRYSTAL STRUCTURE OF EV71 3C PROTEINASE IN COMPLEX WITH COMPOUND VIII
Descriptor:3C proteinase, Nalpha-[(benzyloxy)carbonyl]-N-{(2S)-1-oxo-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-L-phenylalaninamide
Authors:Zhang, L., Huang, G., Cai, Q., Zhao, C., Ren, H., Li, P., Li, N., Chen, S., Li, J., Lin, T.
Deposit date:2015-06-15
Release date:2016-06-01
Last modified:2016-10-26
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Optimize the interactions at S4 with efficient inhibitors targeting 3C proteinase from enterovirus 71
J.Mol.Recognit., 29, 2016
5C1Y
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CRYSTAL STRUCTURE OF EV71 3C PROTEINASE IN COMPLEX WITH COMPOUND 1
Descriptor:3C proteinase, N-{(2S)-1-oxo-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-Nalpha-[(propan-2-yloxy)carbonyl]-L-phenylalaninamide
Authors:Zhang, L., Huang, G., Cai, Q., Zhao, C., Ren, H., Li, P., Li, N., Chen, S., Li, J., Lin, T.
Deposit date:2015-06-15
Release date:2016-06-01
Last modified:2016-10-26
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Optimize the interactions at S4 with efficient inhibitors targeting 3C proteinase from enterovirus 71
J.Mol.Recognit., 29, 2016
5C20
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CRYSTAL STRUCTURE OF EV71 3C PROTEINASE IN COMPLEX WITH COMPOUND 2
Descriptor:3C proteinase, Nalpha-[(2-methylpropoxy)carbonyl]-N-{(2S)-1-oxo-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-L-phenylalaninamide
Authors:Zhang, L., Huang, G., Cai, Q., Zhao, C., Ren, H., Li, P., Li, N., Chen, S., Li, J., Lin, T.
Deposit date:2015-06-15
Release date:2016-06-01
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Optimize the interactions at S4 with efficient inhibitors targeting 3C proteinase from enterovirus 71
J.Mol.Recognit., 29, 2016