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4B8T
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BU of 4b8t by Molmil
RNA BINDING PROTEIN Solution structure of the third KH domain of KSRP in complex with the G-rich target sequence.
Descriptor: 5'-R(*AP*GP*GP*GP*UP)-3', KH-TYPE SPLICING REGULATORY PROTEIN
Authors:Nicastro, G, Garcia-Mayoral, M.F, Hollingworth, D, Kelly, G, Martin, S.R, Briata, P, Gherzi, R, Ramos, A.
Deposit date:2012-08-30
Release date:2012-11-07
Last modified:2013-01-16
Method:SOLUTION NMR
Cite:Noncanonical G Recognition Mediates Ksrp Regulation of Let-7 Biogenesis
Nat.Struct.Mol.Biol., 19, 2012
6Z8C
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BU of 6z8c by Molmil
Crystal Structure of the Voltage-Gated Sodium Channel NavMs (F208L) in complex with N-desmethyltamoxifen (3.2 A resolution)
Descriptor: 2-[4-[(~{Z})-1,2-diphenylbut-1-enyl]phenoxy]-~{N}-methyl-ethanamine, DODECAETHYLENE GLYCOL, HEGA-10, ...
Authors:Sula, A, Hollingworth, D, Wallace, B.A.
Deposit date:2020-06-02
Release date:2021-02-03
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:A tamoxifen receptor within a voltage-gated sodium channel.
Mol.Cell, 81, 2021
2BF0
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BU of 2bf0 by Molmil
crystal structure of the rpr of pcf11
Descriptor: CALCIUM ION, PCF11
Authors:Noble, C.G, Hollingworth, D, Martin, S.R, Adeniran, V.E, Smerdon, S.J, Kelly, G, Taylor, I.A, Ramos, A.
Deposit date:2004-12-02
Release date:2005-01-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Key Features of the Interaction between Pcf11 Cid and RNA Polymerase II Ctd.
Nat.Struct.Mol.Biol., 12, 2005
2BKD
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BU of 2bkd by Molmil
Structure of the N-terminal domain of Fragile X Mental Retardation Protein
Descriptor: Fragile X messenger ribonucleoprotein 1
Authors:Ramos, A, Hollingworth, D, Adinolfi, S, Castets, M, Kelly, G, Frenkiel, T.A, Bardoni, B, Pastore, A.
Deposit date:2005-02-15
Release date:2006-01-18
Last modified:2023-02-01
Method:SOLUTION NMR
Cite:The structure of the N-terminal domain of the fragile X mental retardation protein: a platform for protein-protein interaction.
Structure, 14, 2006
6YZ0
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BU of 6yz0 by Molmil
Full length Open-form Sodium Channel NavMs F208L in complex with Cannabidiol (CBD)
Descriptor: 2-[(1R,2R,5S)-5-methyl-2-(prop-1-en-2-yl)cyclohexyl]-5-pentylbenzene-1,3-diol, DODECAETHYLENE GLYCOL, HEGA-10, ...
Authors:Sula, A, Sait, L.G, Hollingworth, D, Wallace, B.A.
Deposit date:2020-05-06
Release date:2020-11-11
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Cannabidiol interactions with voltage-gated sodium channels.
Elife, 9, 2020
6YZ2
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BU of 6yz2 by Molmil
Full length Open-form Sodium Channel NavMs F208L
Descriptor: DODECAETHYLENE GLYCOL, HEGA-10, Ion transport protein, ...
Authors:Sula, A, Sait, L.G, Hollingworth, D, Wallace, B.A.
Deposit date:2020-05-06
Release date:2020-11-11
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Cannabidiol interactions with voltage-gated sodium channels.
Elife, 9, 2020
2N8M
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BU of 2n8m by Molmil
Zipcode-binding-protein-1 KH3(DD)KH4 domains in complex with the KH4 RNA target
Descriptor: Insulin-like growth factor 2 mRNA-binding protein 1, RNA (5'-R(P*UP*CP*GP*GP*AP*CP*U)-3')
Authors:Nicastro, G, Ramos, A, Candel, A, Hollingworth, D.
Deposit date:2015-10-21
Release date:2017-01-25
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Zipcode-binding-protein-1 KH3(DD)KH4 domains in complex with the RNA target UCGGACU
To be Published
2N8L
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BU of 2n8l by Molmil
Zipcode-binding-protein-1 KH3KH4(DD) domains in complex with the KH3 RNA target
Descriptor: Insulin-like growth factor 2 mRNA-binding protein 1, RNA (5'-R(P*GP*CP*AP*CP*AP*CP*CP*C)-3')
Authors:Nicastro, G, Candel, A.M, Ramos, A, Hollingworth, D.
Deposit date:2015-10-21
Release date:2017-01-25
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Zipcode-binding-protein-1 KH3KH4(DD) domains in complex with the RNA target GCACACCC
To be Published
2JVZ
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BU of 2jvz by Molmil
Solution NMR Structure of the Second and Third KH Domains of KSRP
Descriptor: Far upstream element-binding protein 2
Authors:Diaz-Moreno, I, Hollingworth, D, Garcia-Mayoral, M.F, Kelly, G, Cukier, C.D, Ramos, A.
Deposit date:2007-09-28
Release date:2009-02-17
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution NMR Structure of the Second and Third KH Domains of KSRP
To be Published, 2007
2OPV
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BU of 2opv by Molmil
Solution NMR Structure of the Second Domain of KSRP
Descriptor: KHSRP protein
Authors:Diaz-Moreno, I, Ramos, A, Garcia-Mayoral, M.F, Hollingworth, D.
Deposit date:2007-01-30
Release date:2008-02-26
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:The NMR Structures of the N-terminal Domains of KSRP
To be Published
2OPU
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BU of 2opu by Molmil
Solution NMR Structure of the First Domain of KSRP
Descriptor: KHSRP protein
Authors:Diaz-Moreno, I, Ramos, A, Garcia-Mayoral, M.F, Hollingworth, D.
Deposit date:2007-01-30
Release date:2008-02-26
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Phosphorylation-mediated unfolding of a KH domain regulates KSRP localization via 14-3-3 binding.
Nat.Struct.Mol.Biol., 16, 2009
2KXH
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BU of 2kxh by Molmil
Solution structure of the first two RRM domains of FIR in the complex with FBP Nbox peptide
Descriptor: Poly(U)-binding-splicing factor PUF60, peptide of Far upstream element-binding protein 1
Authors:Cukier, C.D, Ramos, A, Hollingworth, D, Diaz-Moreno, I, Kelly, G.
Deposit date:2010-05-05
Release date:2010-08-18
Last modified:2019-12-18
Method:SOLUTION NMR
Cite:Molecular basis of FIR-mediated c-myc transcriptional control.
Nat.Struct.Mol.Biol., 17, 2010
2KXF
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BU of 2kxf by Molmil
Solution structure of the first two RRM domains of FBP-interacting repressor (FIR)
Descriptor: Poly(U)-binding-splicing factor PUF60
Authors:Cukier, C.D, Ramos, A, Hollingworth, D, Diaz-Moreno, I, Kelly, G.
Deposit date:2010-05-04
Release date:2010-08-18
Last modified:2019-12-18
Method:SOLUTION NMR
Cite:Molecular basis of FIR-mediated c-myc transcriptional control.
Nat.Struct.Mol.Biol., 17, 2010
6SXE
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BU of 6sxe by Molmil
Crystal Structure of the Voltage-Gated Sodium Channel NavMs (F208L) in complex with Endoxifen (2.6 Angstrom resolution)
Descriptor: 2,5,8,11,14,17,20,23-OCTAOXAPENTACOSAN-25-OL, Endoxifen, HEGA-10, ...
Authors:Sula, A, Hollingworth, D, Wallace, B.A.
Deposit date:2019-09-25
Release date:2021-02-03
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:A tamoxifen receptor within a voltage-gated sodium channel.
Mol.Cell, 81, 2021
6SX5
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BU of 6sx5 by Molmil
Full length Mutant Open-form Sodium Channel NavMs
Descriptor: DODECAETHYLENE GLYCOL, HEGA-10, Ion transport protein, ...
Authors:Sula, A, Hollingworth, D, Wallace, B.A.
Deposit date:2019-09-25
Release date:2021-02-03
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:A tamoxifen receptor within a voltage-gated sodium channel.
Mol.Cell, 81, 2021
6SXC
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BU of 6sxc by Molmil
Crystal structure of the Voltage-Gated Sodium Channel NavMs (F208L) in complex with 4-hydroxytamoxifen (2.5 Angstrom resolution)
Descriptor: 4-HYDROXYTAMOXIFEN, DODECAETHYLENE GLYCOL, HEGA-10, ...
Authors:Sula, A, Hollingworth, D, Wallace, B.A.
Deposit date:2019-09-25
Release date:2021-02-03
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:A tamoxifen receptor within a voltage-gated sodium channel.
Mol.Cell, 81, 2021
6SXF
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BU of 6sxf by Molmil
Crystal Structure of the Voltage-Gated Sodium Channel NavMs (F208L) in complex with Tamoxifen (2.8 Angstrom resolution)
Descriptor: (Z)-2-[4-(1,2)-DIPHENYL-1-BUTENYL)-PHENOXY]-N,N-DIMETHYLETHANAMINE, DODECAETHYLENE GLYCOL, HEGA-10, ...
Authors:Sula, A, Hollingworth, D, Wallace, B.A.
Deposit date:2019-09-25
Release date:2021-02-03
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.839 Å)
Cite:A tamoxifen receptor within a voltage-gated sodium channel.
Mol.Cell, 81, 2021
6SX7
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BU of 6sx7 by Molmil
Crystal Structure of the Voltage-Gated Sodium Channel NavMs (F208L) (2.2 Angstrom resolution)
Descriptor: 1-ETHOXY-2-(2-METHOXYETHOXY)ETHANE, DODECAETHYLENE GLYCOL, HEGA-10, ...
Authors:Sula, A, Hollingworth, D, Wallace, B.A.
Deposit date:2019-09-25
Release date:2021-02-03
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:A tamoxifen receptor within a voltage-gated sodium channel.
Mol.Cell, 81, 2021
6SXG
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BU of 6sxg by Molmil
Crystal Structure of the Voltage-Gated Sodium Channel NavMs in complex with 4-hydroxytamoxifen (2.4 Angstrom resolution)
Descriptor: 4-HYDROXYTAMOXIFEN, DODECAETHYLENE GLYCOL, HEGA-10, ...
Authors:Sula, A, Hollingworth, D, Wallace, B.A.
Deposit date:2019-09-25
Release date:2021-02-03
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:A tamoxifen receptor within a voltage-gated sodium channel.
Mol.Cell, 81, 2021
2HH3
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BU of 2hh3 by Molmil
Solution structure of the third KH domain of KSRP
Descriptor: KH-type splicing regulatory protein
Authors:Garcia-Mayoral, M.F.
Deposit date:2006-06-27
Release date:2007-05-08
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:The Structure of the C-Terminal KH Domains of KSRP Reveals a Noncanonical Motif Important for mRNA Degradation.
Structure, 15, 2007
2HH2
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BU of 2hh2 by Molmil
Solution structure of the fourth KH domain of KSRP
Descriptor: KH-type splicing regulatory protein
Authors:Garcia-Mayoral, M.F.
Deposit date:2006-06-27
Release date:2007-05-08
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:The Structure of the C-Terminal KH Domains of KSRP Reveals a Noncanonical Motif Important for mRNA Degradation.
Structure, 15, 2007
8COO
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BU of 8coo by Molmil
Solution structure of Zipcode binding protein 1 (ZBP1) KH3(DD)KH4 domains in complex with N6-Methyladenosine containing RNA
Descriptor: Insulin-like growth factor 2 mRNA-binding protein 1, RNA_(5'-R(*(UP*CP*GP*GP*(6MZ)P*CP*U)-3')
Authors:Nicastro, G, Abis, G, Taylor, I.A, Ramos, A.
Deposit date:2023-02-28
Release date:2024-02-07
Method:SOLUTION NMR
Cite:Direct m6A recognition by IMP1 underlays an alternative model of target selection for non-canonical methyl-readers.
Nucleic Acids Res., 51, 2023

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