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7PGI
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BU of 7pgi by Molmil
NaVAb1p (bicelles)
Descriptor: ACETATE ION, Ion transport protein, MAGNESIUM ION, ...
Authors:Lolicato, M, Arrigoni, C.
Deposit date:2021-08-14
Release date:2022-06-08
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.638 Å)
Cite:Quaternary structure independent folding of voltage-gated ion channel pore domain subunits.
Nat.Struct.Mol.Biol., 29, 2022
7PGF
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BU of 7pgf by Molmil
Calcium-selective Sp1 channel pore domain only
Descriptor: Ion transporter
Authors:Lolicato, M, Arrigoni, C.
Deposit date:2021-08-13
Release date:2022-06-08
Last modified:2022-06-29
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Quaternary structure independent folding of voltage-gated ion channel pore domain subunits.
Nat.Struct.Mol.Biol., 29, 2022
7PG8
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BU of 7pg8 by Molmil
NaV_Ae1/Sp1CTD_pore-ANT05 complex
Descriptor: ANT05 H12 fab fragment, heavy chain, light chain, ...
Authors:Lolicato, M, Arrigoni, C.
Deposit date:2021-08-13
Release date:2022-06-08
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (4.5 Å)
Cite:Quaternary structure independent folding of voltage-gated ion channel pore domain subunits.
Nat.Struct.Mol.Biol., 29, 2022
7PGB
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BU of 7pgb by Molmil
NaV_Ae1/Sp1CTD_pore-SAT09 complex
Descriptor: 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, 4-NITROBENZOIC ACID, ...
Authors:Lolicato, M, Arrigoni, C.
Deposit date:2021-08-13
Release date:2022-06-08
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Quaternary structure independent folding of voltage-gated ion channel pore domain subunits.
Nat.Struct.Mol.Biol., 29, 2022
7PGG
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BU of 7pgg by Molmil
NaVAb1p detergent (DM)
Descriptor: 2-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}ethyl heptadecanoate, Ion transport protein
Authors:Lolicato, M, Arrigoni, C.
Deposit date:2021-08-13
Release date:2022-06-15
Last modified:2022-06-29
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Quaternary structure independent folding of voltage-gated ion channel pore domain subunits.
Nat.Struct.Mol.Biol., 29, 2022
7PGH
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BU of 7pgh by Molmil
NaVAe1/Sp1CTDp (DDM)
Descriptor: 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, DODECAETHYLENE GLYCOL, DODECANE, ...
Authors:Lolicato, M, Arrigoni, C.
Deposit date:2021-08-14
Release date:2022-06-15
Last modified:2022-06-29
Method:X-RAY DIFFRACTION (4.194 Å)
Cite:Quaternary structure independent folding of voltage-gated ion channel pore domain subunits.
Nat.Struct.Mol.Biol., 29, 2022
3U10
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BU of 3u10 by Molmil
Tetramerization dynamics of the C-terminus underlies isoform-specific cAMP-gating in HCN channels
Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2
Authors:Lolicato, M, Nardini, M, Gazzarrini, S, Moller, S, Bertinetti, D, Herberg, F.W, Bolognesi, M, Martin, H, Fasolini, M, Bertrand, J.A, Arrigoni, C, Thiel, G, Moroni, A.
Deposit date:2011-09-29
Release date:2011-10-26
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Tetramerization dynamics of C-terminal domain underlies isoform-specific cAMP gating in hyperpolarization-activated cyclic nucleotide-gated channels.
J.Biol.Chem., 286, 2011
3U0Z
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BU of 3u0z by Molmil
Tetramerization dynamics of the C-terminus underlies isoform-specific cAMP-gating in HCN channels
Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1
Authors:Lolicato, M, Nardini, M, Gazzarrini, S, Moller, S, Bertinetti, D, Herberg, F.W, Bolognesi, M, Martin, H, Fasolini, M, Bertrand, J.A, Arrigoni, C, Thiel, G, Moroni, A.
Deposit date:2011-09-29
Release date:2011-10-26
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Tetramerization dynamics of C-terminal domain underlies isoform-specific cAMP gating in hyperpolarization-activated cyclic nucleotide-gated channels.
J.Biol.Chem., 286, 2011
3U11
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BU of 3u11 by Molmil
Tetramerization dynamics of the C-terminus underlies isoform-specific cAMP-gating in HCN channels
Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, GLYCEROL, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4
Authors:Lolicato, M, Nardini, M, Gazzarrini, S, Moller, S, Bertinetti, D, Herberg, F.W, Bolognesi, M, Martin, H, Fasolini, M, Bertrand, J.A, Arrigoni, C, Thiel, G, Moroni, A.
Deposit date:2011-09-29
Release date:2011-10-26
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Tetramerization dynamics of C-terminal domain underlies isoform-specific cAMP gating in hyperpolarization-activated cyclic nucleotide-gated channels.
J.Biol.Chem., 286, 2011
4KL1
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BU of 4kl1 by Molmil
HCN4 CNBD in complex with cGMP
Descriptor: ACETATE ION, CYCLIC GUANOSINE MONOPHOSPHATE, GLYCEROL, ...
Authors:Lolicato, M, Arrigoni, C, Zucca, S, Nardini, M, Bucchi, A, Schroeder, I, Simmons, K, Bolognesi, M, DiFrancesco, D, Schwede, F, Fishwick, C.W.G, Johnson, A.P.K, Thiel, G, Moroni, A.
Deposit date:2013-05-07
Release date:2014-04-30
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Cyclic dinucleotides bind the C-linker of HCN4 to control channel cAMP responsiveness.
Nat.Chem.Biol., 10, 2014
4LTP
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BU of 4ltp by Molmil
Bacterial sodium channel in high calcium, I222 space group, crystal 2
Descriptor: CALCIUM ION, Ion transport protein
Authors:Shaya, D, Findeisen, F, Abderemane-Ali, F, Arrigoni, C, Wong, S, Reddy Nurva, S, Loussouarn, G, Minor, D.L.
Deposit date:2013-07-23
Release date:2013-10-23
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Structure of a prokaryotic sodium channel pore reveals essential gating elements and an outer ion binding site common to eukaryotic channels.
J.Mol.Biol., 426, 2014
4LTO
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BU of 4lto by Molmil
Bacterial sodium channel in high calcium, I222 space group
Descriptor: CALCIUM ION, Ion transport protein, NICKEL (II) ION
Authors:Shaya, D, Findeisen, F, Abderemane-Ali, F, Arrigoni, C, Wong, S, Reddy Nurva, S, Loussouarn, G, Minor, D.L.
Deposit date:2013-07-23
Release date:2013-10-23
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.46 Å)
Cite:Structure of a prokaryotic sodium channel pore reveals essential gating elements and an outer ion binding site common to eukaryotic channels.
J.Mol.Biol., 426, 2014
4LTR
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BU of 4ltr by Molmil
Bacterial sodium channel, His245Gly mutant, I222 space group
Descriptor: Ion transport protein
Authors:Shaya, D, Findeisen, F, Abderemane-Ali, F, Arrigoni, C, Wong, S, Reddy Nurva, S, Loussouarn, G, Minor, D.L.
Deposit date:2013-07-23
Release date:2013-10-23
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (5.8 Å)
Cite:Structure of a prokaryotic sodium channel pore reveals essential gating elements and an outer ion binding site common to eukaryotic channels.
J.Mol.Biol., 426, 2014
4LTQ
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BU of 4ltq by Molmil
Bacterial sodium channel in low calcium, P42 space group
Descriptor: Ion transport protein
Authors:Shaya, D, Findeisen, F, Abderemane-Ali, F, Arrigoni, C, Wong, S, Reddy Nurva, S, Loussouarn, G, Minor, D.L.
Deposit date:2013-07-23
Release date:2013-10-23
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (5.5 Å)
Cite:Structure of a prokaryotic sodium channel pore reveals essential gating elements and an outer ion binding site common to eukaryotic channels.
J.Mol.Biol., 426, 2014
5HK7
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BU of 5hk7 by Molmil
Bacterial sodium channel pore, 2.95 Angstrom resolution
Descriptor: 2-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}ethyl heptadecanoate, CHLORIDE ION, Ion transport protein, ...
Authors:Shaya, D, Findeisen, F, Rohaim, A, Minor, D.L.
Deposit date:2016-01-14
Release date:2016-03-09
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Unfolding of a Temperature-Sensitive Domain Controls Voltage-Gated Channel Activation.
Cell, 164, 2016
5HJ8
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BU of 5hj8 by Molmil
Bacterial sodium channel neck 3G mutant
Descriptor: CALCIUM ION, Ion transport protein
Authors:Rohaim, A, Minor, D.L.
Deposit date:2016-01-13
Release date:2016-03-09
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Unfolding of a Temperature-Sensitive Domain Controls Voltage-Gated Channel Activation.
Cell, 164, 2016
5HK6
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BU of 5hk6 by Molmil
Bacterial sodium channel neck 3G mutant, SAD
Descriptor: Ion transport protein
Authors:Rohaim, A, Minor, D.L.
Deposit date:2016-01-13
Release date:2016-03-09
Method:X-RAY DIFFRACTION (5.5 Å)
Cite:Unfolding of a Temperature-Sensitive Domain Controls Voltage-Gated Channel Activation.
Cell, 164, 2016
5HKD
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BU of 5hkd by Molmil
Bacterial sodium channel neck 7G mutant
Descriptor: CALCIUM ION, Ion transport protein
Authors:Rohaim, A, Minor, D.L.
Deposit date:2016-01-13
Release date:2016-03-09
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Unfolding of a Temperature-Sensitive Domain Controls Voltage-Gated Channel Activation.
Cell, 164, 2016
5IWO
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BU of 5iwo by Molmil
Bacterial sodium channel pore domain, low bromide
Descriptor: BROMIDE ION, Ion transport protein
Authors:Shaya, D, Findeisen, F, Rohaim, A, Minor, D.L.
Deposit date:2016-03-22
Release date:2016-03-30
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.33 Å)
Cite:Unfolding of a Temperature-Sensitive Domain Controls Voltage-Gated Channel Activation.
Cell, 164, 2016
5IWN
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BU of 5iwn by Molmil
Bacterial sodium channel pore domain, high bromide
Descriptor: BROMIDE ION, Ion transport protein
Authors:Shaya, D, Findeisen, F, Rohaim, A, Minor, D.L.
Deposit date:2016-03-22
Release date:2016-03-30
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.75 Å)
Cite:Unfolding of a Temperature-Sensitive Domain Controls Voltage-Gated Channel Activation.
Cell, 164, 2016
6CQ6
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BU of 6cq6 by Molmil
K2P2.1(TREK-1) apo structure
Descriptor: CADMIUM ION, DECANE, POTASSIUM ION, ...
Authors:Lolicato, M, Minor, D.L.
Deposit date:2018-03-14
Release date:2018-03-28
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:K2P2.1 (TREK-1)-activator complexes reveal a cryptic selectivity filter binding site.
Nature, 547, 2017
6CQ9
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BU of 6cq9 by Molmil
K2P2.1(TREK-1):ML402 complex
Descriptor: CADMIUM ION, HEXADECANE, N-((E,2S,3R)-1,3-DIHYDROXYOCTADEC-4-EN-2-YL)PALMITAMIDE, ...
Authors:Lolicato, M, Minor, D.L.
Deposit date:2018-03-14
Release date:2018-04-11
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:K2P2.1 (TREK-1)-activator complexes reveal a cryptic selectivity filter binding site.
Nature, 547, 2017
6CQ8
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BU of 6cq8 by Molmil
K2P2.1(TREK-1):ML335 complex
Descriptor: CADMIUM ION, HEXADECANE, N-((E,2S,3R)-1,3-DIHYDROXYOCTADEC-4-EN-2-YL)PALMITAMIDE, ...
Authors:Lolicato, M, Minor, D.L.
Deposit date:2018-03-14
Release date:2018-03-28
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3 Å)
Cite:K2P2.1 (TREK-1)-activator complexes reveal a cryptic selectivity filter binding site.
Nature, 547, 2017
4RUE
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BU of 4rue by Molmil
Human K2P4.1 (TRAAK) potassium channel, G124I mutant
Descriptor: POTASSIUM ION, Potassium channel subfamily K member 4
Authors:Lolicato, M, Minor, D.L.Jr.
Deposit date:2014-11-19
Release date:2014-12-17
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Transmembrane Helix Straightening and Buckling Underlies Activation of Mechanosensitive and Thermosensitive K2P Channels.
Neuron, 84, 2014
4RUF
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BU of 4ruf by Molmil
Human K2P4.1 (TRAAAK) potassium channel, W262S mutant
Descriptor: POTASSIUM ION, Potassium channel subfamily K member 4
Authors:Lolicato, M, Minor, D.L.Jr.
Deposit date:2014-11-19
Release date:2014-12-17
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Transmembrane Helix Straightening and Buckling Underlies Activation of Mechanosensitive and Thermosensitive K2P Channels.
Neuron, 84, 2014

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PDB entries from 2024-03-27

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