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1BX0
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BU of 1bx0 by Molmil
Ferredoxin:nadp+ oxidoreductase (ferredoxin reductase) mutant e312l
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, PHOSPHATE ION, PROTEIN (FERREDOXIN:NADP+ OXIDOREDUCTASE), ...
Authors:Aliverti, A, Deng, Z, Ravasi, D, Piubelli, L, Karplus, P.A, Zanetti, G.
Deposit date:1998-10-10
Release date:1998-10-14
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Probing the function of the invariant glutamyl residue 312 in spinach ferredoxin-NADP+ reductase.
J.Biol.Chem., 273, 1998
1BX1
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BU of 1bx1 by Molmil
FERREDOXIN:NADP+ OXIDOREDUCTASE (FERREDOXIN REDUCTASE) MUTANT E312Q
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, PHOSPHATE ION, PROTEIN (FERREDOXIN:NADP+ OXIDOREDUCTASE), ...
Authors:Aliverti, A, Deng, Z, Ravasi, D, Piubelli, L, Karplus, P.A, Zanetti, G.
Deposit date:1998-10-10
Release date:1998-10-14
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Probing the function of the invariant glutamyl residue 312 in spinach ferredoxin-NADP+ reductase.
J.Biol.Chem., 273, 1998
1FRQ
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BU of 1frq by Molmil
FERREDOXIN:NADP+ OXIDOREDUCTASE (FERREDOXIN REDUCTASE) MUTANT E312A
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, PHOSPHATE ION, PROTEIN (FERREDOXIN:NADP+ OXIDOREDUCTASE), ...
Authors:Aliverti, A, Deng, Z, Ravasi, D, Piubelli, L, Karplus, P.A, Zanetti, G.
Deposit date:1998-10-10
Release date:1998-10-14
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Probing the function of the invariant glutamyl residue 312 in spinach ferredoxin-NADP+ reductase.
J.Biol.Chem., 273, 1998
1JB9
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BU of 1jb9 by Molmil
Crystal Structure of The Ferredoxin:NADP+ Reductase From Maize Root AT 1.7 Angstroms
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, ferredoxin-NADP reductase
Authors:Faber, H.R, Karplus, P.A, Aliverti, A, Ferioli, C, Spinola, M.
Deposit date:2001-06-03
Release date:2001-07-04
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Biochemical and crystallographic characterization of ferredoxin-NADP(+) reductase from nonphotosynthetic tissues.
Biochemistry, 40, 2001
3LVB
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BU of 3lvb by Molmil
Crystal structure of the Ferredoxin:NADP+ reductase from maize root at 1.7 angstroms - Test Set Withheld
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, Ferredoxin-NADP reductase
Authors:Faber, H.R, Karplus, P.A, Aliverti, A, Ferioli, C, Spinola, M.
Deposit date:2010-02-19
Release date:2010-03-16
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Biochemical and crystallographic characterization of ferredoxin-NADP(+) reductase from nonphotosynthetic tissues
Biochemistry, 40, 2001
1A70
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BU of 1a70 by Molmil
SPINACH FERREDOXIN
Descriptor: FE2/S2 (INORGANIC) CLUSTER, FERREDOXIN
Authors:Binda, C, Coda, A, Mattevi, A, Aliverti, A, Zanetti, G.
Deposit date:1998-03-19
Release date:1998-11-25
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure of the mutant E92K of [2Fe-2S] ferredoxin I from Spinacia oleracea at 1.7 A resolution.
Acta Crystallogr.,Sect.D, 54, 1998
2C7G
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BU of 2c7g by Molmil
FprA from Mycobacterium tuberculosis: His57Gln mutant
Descriptor: 4-OXO-NICOTINAMIDE-ADENINE DINUCLEOTIDE PHOSPHATE, FLAVIN-ADENINE DINUCLEOTIDE, NADPH-FERREDOXIN REDUCTASE FPRA, ...
Authors:Pennati, A, Razeto, A, De Rosa, M, Pandini, V, Vanoni, M.A, Aliverti, A, Mattevi, A, Coda, A, Zanetti, G.
Deposit date:2005-11-24
Release date:2006-07-26
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Role of the His57-Glu214 Ionic Couple Located in the Active Site of Mycobacterium Tuberculosis Fpra.
Biochemistry, 45, 2006
2UUU
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BU of 2uuu by Molmil
alkyldihydroxyacetonephosphate synthase in P212121
Descriptor: ALKYLDIHYDROXYACETONEPHOSPHATE SYNTHASE, FLAVIN-ADENINE DINUCLEOTIDE, HEXADECAN-1-OL
Authors:Razeto, A, Mattiroli, F, Carpanelli, E, Aliverti, A, Pandini, V, Coda, A, Mattevi, A.
Deposit date:2007-03-07
Release date:2007-06-26
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:The Crucial Step in Ether Phospholipid Biosynthesis: Structural Basis of a Noncanonical Reaction Associated with a Peroxisomal Disorder.
Structure, 15, 2007
2V2K
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BU of 2v2k by Molmil
THE CRYSTAL STRUCTURE OF FDXA, A 7FE FERREDOXIN FROM MYCOBACTERIUM SMEGMATIS
Descriptor: ACETATE ION, FE3-S4 CLUSTER, FERREDOXIN
Authors:Ricagno, S, de Rosa, M, Aliverti, A, Zanetti, G, Bolognesi, M.
Deposit date:2007-06-06
Release date:2007-07-03
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The Crystal Structure of Fdxa, a 7Fe Ferredoxin from Mycobacterium Smegmatis.
Biochem.Biophys.Res.Commun., 360, 2007
5AE1
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BU of 5ae1 by Molmil
Ether Lipid-Generating Enzyme AGPS in complex with inhibitor ZINC69435460
Descriptor: (3-(2-FLUOROPHENYL)-N-(1-(2-OXO-2,3-DIHYDRO-1H-BENZO[D]IMIDAZOL-5-YL)ETHYL)BUTANAMIDE), ALKYLDIHYDROXYACETONEPHOSPHATE SYNTHASE, PEROXISOMAL, ...
Authors:Piano, V, Benjamin, D.I, Valente, S, Nenci, S, Marrocco, B, Mai, A, Aliverti, A, Nomura, D.K, Mattevi, A.
Deposit date:2015-08-25
Release date:2015-09-09
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Discovery of Inhibitors for the Ether Lipid-Generating Enzyme Agps as Anti-Cancer Agents.
Acs Chem.Biol., 10, 2015
5ADZ
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BU of 5adz by Molmil
Ether Lipid-Generating Enzyme AGPS in complex with inhibitor 1a
Descriptor: (3S)-3-(2-fluorophenyl)-N-((2-oxo-2,3-dihydro-1H-benzo[d]imidazol-5-yl)methyl)butanamide), ALKYLDIHYDROXYACETONEPHOSPHATE SYNTHASE, PEROXISOMAL, ...
Authors:Piano, V, Benjamin, D.I, Valente, S, Nenci, S, Marrocco, B, Mai, A, Aliverti, A, Nomura, D.K, Mattevi, A.
Deposit date:2015-08-25
Release date:2015-09-23
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Discovery of Inhibitors for the Ether Lipid-Generating Enzyme Agps as Anti-Cancer Agents.
Acs Chem.Biol., 10, 2015
5AE2
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BU of 5ae2 by Molmil
Ether Lipid-Generating Enzyme AGPS in complex with inhibitor 1e
Descriptor: 3-(2-fluorophenyl)-2-methyl-N-((2-oxo-2,3-dihydro-1H-benzo[d]imidazol-5-yl)methyl)acrylamide, ALKYLDIHYDROXYACETONEPHOSPHATE SYNTHASE, PEROXISOMAL, ...
Authors:Piano, V, Benjamin, D.I, Valente, S, Nenci, S, Marrocco, B, Mai, A, Aliverti, A, Nomura, D.K, Mattevi, A.
Deposit date:2015-08-25
Release date:2015-09-09
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2 Å)
Cite:Discovery of Inhibitors for the Ether Lipid-Generating Enzyme Agps as Anti-Cancer Agents.
Acs Chem.Biol., 10, 2015
5AE3
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BU of 5ae3 by Molmil
Ether Lipid-Generating Enzyme AGPS in complex with antimycin A
Descriptor: ALKYLDIHYDROXYACETONEPHOSPHATE SYNTHASE, PEROXISOMAL, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Piano, V, Benjamin, D.I, Valente, S, Nenci, S, Marrocco, B, Mai, A, Aliverti, A, Nomura, D.K, Mattevi, A.
Deposit date:2015-08-25
Release date:2015-09-09
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Discovery of Inhibitors for the Ether Lipid-Generating Enzyme Agps as Anti-Cancer Agents.
Acs Chem.Biol., 10, 2015
2UUV
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BU of 2uuv by Molmil
alkyldihydroxyacetonephosphate synthase in P1
Descriptor: ALKYLDIHYDROXYACETONEPHOSPHATE SYNTHASE, FLAVIN-ADENINE DINUCLEOTIDE, HEXADECAN-1-OL
Authors:Razeto, A, Mattiroli, F, Carpanelli, E, Aliverti, A, Pandini, V, Coda, A, Mattevi, A.
Deposit date:2007-03-07
Release date:2007-06-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:The Crucial Step in Ether Phospholipid Biosynthesis: Structural Basis of a Noncanonical Reaction Associated with a Peroxisomal Disorder.
Structure, 15, 2007
1LQT
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BU of 1lqt by Molmil
A covalent modification of NADP+ revealed by the atomic resolution structure of FprA, a Mycobacterium tuberculosis oxidoreductase
Descriptor: 4-OXO-NICOTINAMIDE-ADENINE DINUCLEOTIDE PHOSPHATE, ACETATE ION, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Bossi, R.T, Aliverti, A, Raimondi, D, Fischer, F, Zanetti, G, Ferrari, D, Tahallah, N, Maier, C.S, Heck, A.J.R, Rizzi, M, Mattevi, A, TB Structural Genomics Consortium (TBSGC)
Deposit date:2002-05-13
Release date:2002-07-31
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.05 Å)
Cite:A covalent modification of NADP+ revealed by the atomic resolution structure of FprA, a Mycobacterium tuberculosis oxidoreductase.
Biochemistry, 41, 2002
1LQU
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BU of 1lqu by Molmil
Mycobacterium tuberculosis FprA in complex with NADPH
Descriptor: ACETATE ION, FLAVIN-ADENINE DINUCLEOTIDE, FprA, ...
Authors:Bossi, R.T, Aliverti, A, Raimondi, D, Fischer, F, Zanetti, G, Ferrari, D, Tahallah, N, Maier, C.S, Heck, A.J.R, Rizzi, M, Mattevi, A, TB Structural Genomics Consortium (TBSGC)
Deposit date:2002-05-13
Release date:2002-07-31
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:A covalent modification of NADP+ revealed by the atomic resolution structure of FprA, a Mycobacterium tuberculosis oxidoreductase.
Biochemistry, 41, 2002
3QJ4
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BU of 3qj4 by Molmil
Crystal structure of Human Renalase (isoform 1)
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, Renalase, SULFATE ION
Authors:Milani, M, Ciriello, F, Baroni, S, Pandini, V, Aliverti, A, Canevari, G, Bolognesi, M.
Deposit date:2011-01-28
Release date:2011-07-13
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:FAD-binding site and NADP reactivity in human renalase: a new enzyme involved in blood pressure regulation
J.Mol.Biol., 411, 2011
4BCA
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BU of 4bca by Molmil
MAMMALIAN ALKYLDIHYDROXYACETONEPHOSPHATE SYNTHASE: Tyr578Phe mutant
Descriptor: ALKYLDIHYDROXYACETONEPHOSPHATE SYNTHASE, PEROXISOMAL, CHLORIDE ION, ...
Authors:Nenci, S, Piano, V, Rosati, S, Aliverti, A, Pandini, V, Fraaije, M.W, Heck, A.J.R, Edmondson, D.E, Mattevi, A.
Deposit date:2012-10-01
Release date:2012-11-07
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Precursor of Ether Phospholipids is Synthesized by a Flavoenzyme Through Covalent Catalysis.
Proc.Natl.Acad.Sci.USA, 109, 2012
4BBY
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BU of 4bby by Molmil
MAMMALIAN ALKYLDIHYDROXYACETONEPHOSPHATE SYNTHASE: WILD-TYPE
Descriptor: ALKYLDIHYDROXYACETONEPHOSPHATE SYNTHASE, PEROXISOMAL, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Nenci, S, Piano, V, Rosati, S, Aliverti, A, Pandini, V, Fraaije, M.W, Heck, A.J.R, Edmondson, D.E, Mattevi, A.
Deposit date:2012-09-28
Release date:2012-11-07
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Precursor of Ether Phospholipids is Synthesized by a Flavoenzyme Through Covalent Catalysis.
Proc.Natl.Acad.Sci.USA, 109, 2012
4BC9
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BU of 4bc9 by Molmil
MAMMALIAN ALKYLDIHYDROXYACETONEPHOSPHATE SYNTHASE: WILD-TYPE, ADDUCT WITH CYANOETHYL
Descriptor: ALKYLDIHYDROXYACETONEPHOSPHATE SYNTHASE, PEROXISOMAL, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Nenci, S, Piano, V, Rosati, S, Aliverti, A, Pandini, V, Fraaije, M.W, Heck, A.J.R, Edmondson, D.E, Mattevi, A.
Deposit date:2012-10-01
Release date:2012-11-07
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:Precursor of Ether Phospholipids is Synthesized by a Flavoenzyme Through Covalent Catalysis.
Proc.Natl.Acad.Sci.USA, 109, 2012
4BC7
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BU of 4bc7 by Molmil
MAMMALIAN ALKYLDIHYDROXYACETONEPHOSPHATE SYNTHASE: Arg419His mutant
Descriptor: 1-DODECANOL, ALKYLDIHYDROXYACETONEPHOSPHATE SYNTHASE, PEROXISOMAL, ...
Authors:Nenci, S, Piano, V, Rosati, S, Aliverti, A, Pandini, V, Fraaije, M.W, Heck, A.J.R, Edmondson, D.E, Mattevi, A.
Deposit date:2012-10-01
Release date:2012-11-07
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Precursor of Ether Phospholipids is Synthesized by a Flavoenzyme Through Covalent Catalysis.
Proc.Natl.Acad.Sci.USA, 109, 2012
5LP6
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BU of 5lp6 by Molmil
Crystal structure of Tubulin-Stathmin-TTL-Thiocolchicine Complex
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, CHLORIDE ION, ...
Authors:Marangon, J, Christodoulou, M, Casagrande, F, Tiana, G, Dalla Via, L, Aliverti, A, Passarella, D, Cappelletti, G, Ricagno, S.
Deposit date:2016-08-11
Release date:2016-09-21
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Tools for the rational design of bivalent microtubule-targeting drugs.
Biochem. Biophys. Res. Commun., 479, 2016
5MIV
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BU of 5miv by Molmil
G307E variant of murine Apoptosis Inducing Factor in complex with NAD+
Descriptor: Apoptosis-inducing factor 1, mitochondrial, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Sorrentino, L, Cossu, F, Aliverti, A, Milani, M, Mastrangelo, E.
Deposit date:2016-11-29
Release date:2017-07-12
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural bases of the altered catalytic properties of a pathogenic variant of apoptosis inducing factor.
Biochem. Biophys. Res. Commun., 490, 2017
5MIU
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BU of 5miu by Molmil
G307E variant of Murine Apoptosis Inducing Factor (oxidized state)
Descriptor: Apoptosis-inducing factor 1, mitochondrial, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Sorrentino, L, Cossu, F, Milani, M, Aliverti, A, Mastrangelo, E.
Deposit date:2016-11-29
Release date:2017-07-12
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structural bases of the altered catalytic properties of a pathogenic variant of apoptosis inducing factor.
Biochem. Biophys. Res. Commun., 490, 2017
1QFY
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BU of 1qfy by Molmil
PEA FNR Y308S MUTANT IN COMPLEX WITH NADP+
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, PROTEIN (FERREDOXIN: NADP+ REDUCTASE), ...
Authors:Deng, Z, Aliverti, A, Zanetti, G, Arakaki, A.K, Ottado, J, Orellano, E.G, Calcaterra, N.B, Ceccarelli, E.A, Carrillo, N, Karplus, P.A.
Deposit date:1999-04-18
Release date:1999-04-27
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A productive NADP+ binding mode of ferredoxin-NADP + reductase revealed by protein engineering and crystallographic studies.
Nat.Struct.Biol., 6, 1999

 

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