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4V5E
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BU of 4v5e by Molmil
Insights into translational termination from the structure of RF2 bound to the ribosome
Descriptor: 16S ribosomal RNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ...
Authors:Weixlbaumer, A, Jin, H, Neubauer, C, Voorhees, R.M, Petry, S, Kelley, A.C, Ramakrishnan, V.
Deposit date:2009-04-30
Release date:2014-07-09
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.45 Å)
Cite:Insights Into Translational Termination from the Structure of Rf2 Bound to the Ribosome.
Science, 322, 2008
4V5A
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BU of 4v5a by Molmil
Structure of the Ribosome Recycling Factor bound to the Thermus thermophilus 70S ribosome with mRNA, ASL-Phe and tRNA-fMet
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S RIBOSOMAL PROTEIN S10, ...
Authors:Weixlbaumer, A, Petry, S, Dunham, C.M, Selmer, M, Kelley, A.C, Ramakrishnan, V.
Deposit date:2007-06-28
Release date:2014-07-09
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Crystal structure of the ribosome recycling factor bound to the ribosome.
Nat. Struct. Mol. Biol., 14, 2007
4GZZ
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BU of 4gzz by Molmil
Crystal structures of bacterial RNA Polymerase paused elongation complexes
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Weixlbaumer, A, Leon, K, Landick, R, Darst, S.A.
Deposit date:2012-09-06
Release date:2013-02-13
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (4.2927 Å)
Cite:Structural basis of transcriptional pausing in bacteria.
Cell(Cambridge,Mass.), 152, 2013
4GZY
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BU of 4gzy by Molmil
Crystal structures of bacterial RNA Polymerase paused elongation complexes
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Weixlbaumer, A, Leon, K, Landick, R, Darst, S.A.
Deposit date:2012-09-06
Release date:2013-02-13
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.5054 Å)
Cite:Structural basis of transcriptional pausing in bacteria.
Cell(Cambridge,Mass.), 152, 2013
2UUB
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BU of 2uub by Molmil
Structure of the Thermus thermophilus 30S ribosomal subunit complexed with a Valine-ASL with cmo5U in position 34 bound to an mRNA with a GUU-codon in the A-site and paromomycin.
Descriptor: 16S Ribosomal RNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ...
Authors:Weixlbaumer, A, Murphy, F.V, Dziergowska, A, Malkiewicz, A, Vendeix, F.A.P, Agris, P.F, Ramakrishnan, V.
Deposit date:2007-03-01
Release date:2007-05-15
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Mechanism for Expanding the Decoding Capacity of Transfer Rnas by Modification of Uridines
Nat.Struct.Mol.Biol., 14, 2007
2UUA
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BU of 2uua by Molmil
Structure of the Thermus thermophilus 30S ribosomal subunit complexed with a Valine-ASL with cmo5U in position 34 bound to an mRNA with a GUC-codon in the A-site and paromomycin.
Descriptor: 16S RRNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ...
Authors:Weixlbaumer, A, Murphy, F.V, Dziergowska, A, Malkiewicz, A, Vendeix, F.A.P, Agris, P.F, Ramakrishnan, V.
Deposit date:2007-03-01
Release date:2007-05-15
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Mechanism for expanding the decoding capacity of transfer RNAs by modification of uridines.
Nat. Struct. Mol. Biol., 14, 2007
2UU9
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BU of 2uu9 by Molmil
Structure of the Thermus thermophilus 30S ribosomal subunit complexed with a Valine-ASL with cmo5U in position 34 bound to an mRNA with a GUG-codon in the A-site and paromomycin.
Descriptor: 16S RRNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ...
Authors:Weixlbaumer, A, Murphy, F.V, Dziergowska, A, Malkiewicz, A, Vendeix, F.A.P, Agris, P.F, Ramakrishnan, V.
Deposit date:2007-03-01
Release date:2007-05-15
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Mechanism for expanding the decoding capacity of transfer RNAs by modification of uridines.
Nat. Struct. Mol. Biol., 14, 2007
2UUC
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BU of 2uuc by Molmil
Structure of the Thermus thermophilus 30S ribosomal subunit complexed with a Valine-ASL with cmo5U in position 34 bound to an mRNA with a GUA-codon in the A-site and paromomycin.
Descriptor: 16S Ribosomal RNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ...
Authors:Weixlbaumer, A, Murphy, F.V, Dziergowska, A, Malkiewicz, A, Vendeix, F.A.P, Agris, P.F, Ramakrishnan, V.
Deposit date:2007-03-01
Release date:2007-05-22
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Mechanism for expanding the decoding capacity of transfer RNAs by modification of uridines.
Nat. Struct. Mol. Biol., 14, 2007
8AC0
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BU of 8ac0 by Molmil
RNA polymerase at U-rich pause bound to regulatory RNA putL - active, closed clamp state
Descriptor: DNA Non-template strand, DNA Template strand, DNA-directed RNA polymerase subunit alpha, ...
Authors:Weixlbaumer, A, Dey, S.
Deposit date:2022-07-05
Release date:2022-10-19
Last modified:2022-11-02
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structural insights into RNA-mediated transcription regulation in bacteria.
Mol.Cell, 82, 2022
8ABZ
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BU of 8abz by Molmil
RNA polymerase at U-rich pause bound to non-regulatory RNA - pause prone, closed clamp state
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Dey, S, Weixlbaumer, A.
Deposit date:2022-07-05
Release date:2022-10-19
Last modified:2022-11-02
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural insights into RNA-mediated transcription regulation in bacteria.
Mol.Cell, 82, 2022
8AC2
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BU of 8ac2 by Molmil
RNA polymerase- post-terminated, open clamp state
Descriptor: DNA Non-template strand, DNA Template strand, DNA-directed RNA polymerase subunit alpha, ...
Authors:Dey, S, Weixlbaumer, A.
Deposit date:2022-07-05
Release date:2022-10-19
Last modified:2022-11-02
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structural insights into RNA-mediated transcription regulation in bacteria.
Mol.Cell, 82, 2022
8AC1
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BU of 8ac1 by Molmil
RNA polymerase at U-rich pause bound to non-regulatory RNA - inactive, open clamp state
Descriptor: DNA Non-template strand, DNA Template strand, DNA-directed RNA polymerase subunit alpha, ...
Authors:Dey, S, Weixlbaumer, A.
Deposit date:2022-07-05
Release date:2022-10-26
Last modified:2022-11-02
Method:ELECTRON MICROSCOPY (4.06 Å)
Cite:Structural insights into RNA-mediated transcription regulation in bacteria.
Mol.Cell, 82, 2022
8ABY
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BU of 8aby by Molmil
RNA polymerase bound to purified in vitro transcribed regulatory RNA putL - pause prone, closed clamp state
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Dey, S, Weixlbaumer, A.
Deposit date:2022-07-05
Release date:2022-10-19
Last modified:2022-11-02
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structural insights into RNA-mediated transcription regulation in bacteria.
Mol.Cell, 82, 2022
8ACP
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BU of 8acp by Molmil
RNA polymerase at U-rich pause bound to regulatory RNA putL - inactive, open clamp state
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Dey, S, Weixlbaumer, A.
Deposit date:2022-07-06
Release date:2022-10-19
Last modified:2022-11-02
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Structural insights into RNA-mediated transcription regulation in bacteria.
Mol.Cell, 82, 2022
8AD1
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BU of 8ad1 by Molmil
RNA polymerase at U-rich pause bound to RNA putL triple mutant - pause prone, closed clamp state
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Dey, S, Weixlbaumer, A.
Deposit date:2022-07-07
Release date:2022-10-19
Last modified:2022-11-02
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structural insights into RNA-mediated transcription regulation in bacteria.
Mol.Cell, 82, 2022
6FLQ
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BU of 6flq by Molmil
CryoEM structure of E.coli RNA polymerase paused elongation complex bound to NusA
Descriptor: DNA (31-MER), DNA (39-MER), DNA-directed RNA polymerase subunit alpha, ...
Authors:Guo, X, Weixlbaumer, A.
Deposit date:2018-01-26
Release date:2018-03-21
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structural Basis for NusA Stabilized Transcriptional Pausing.
Mol. Cell, 69, 2018
6FLP
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BU of 6flp by Molmil
CryoEM structure of E.coli RNA polymerase paused elongation complex without RNA hairpin bound to NusA
Descriptor: DNA (30-MER), DNA (39-MER), DNA-directed RNA polymerase subunit alpha, ...
Authors:Guo, X, Weixlbaumer, A.
Deposit date:2018-01-26
Release date:2018-03-07
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structural Basis for NusA Stabilized Transcriptional Pausing.
Mol. Cell, 69, 2018
4V5C
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BU of 4v5c by Molmil
Structure of the Thermus thermophilus 70S ribosome in complex with mRNA, paromomycin, acylated A-site tRNA, deacylated P-site tRNA, and E-site tRNA.
Descriptor: 16S ribosomal RNA, 23S Ribosomal RNA, 30S RIBOSOMAL PROTEIN S10, ...
Authors:Voorhees, R.M, Weixlbaumer, A, Loakes, D, Kelley, A.C, Ramakrishnan, V.
Deposit date:2009-03-24
Release date:2014-07-09
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Insights Into Substrate Stabilization from Snapshots of the Peptidyl Transferase Center of the Intact 70S Ribosome
Nat.Struct.Mol.Biol., 16, 2009
4V5D
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BU of 4v5d by Molmil
Structure of the Thermus thermophilus 70S ribosome in complex with mRNA, paromomycin, acylated A- and P-site tRNAs, and E-site tRNA.
Descriptor: 16S ribosomal RNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ...
Authors:Voorhees, R.M, Weixlbaumer, A, Loakes, D, Kelley, A.C, Ramakrishnan, V.
Deposit date:2009-03-24
Release date:2014-07-09
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Insights into substrate stabilization from snapshots of the peptidyl transferase center of the intact 70S ribosome.
Nat. Struct. Mol. Biol., 16, 2009
4V51
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BU of 4v51 by Molmil
Structure of the Thermus thermophilus 70S ribosome complexed with mRNA, tRNA and paromomycin
Descriptor: 16S ribosomal RNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ...
Authors:Selmer, M, Dunham, C.M, Murphy, F.V, Weixlbaumer, A, Petry, S, Weir, J.R, Kelley, A.C, Ramakrishnan, V.
Deposit date:2006-07-31
Release date:2014-07-09
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of the 70S ribosome complexed with mRNA and tRNA.
Science, 313, 2006
4V5F
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BU of 4v5f by Molmil
The structure of the ribosome with elongation factor G trapped in the post-translocational state
Descriptor: 16S ribosomal RNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ...
Authors:Gao, Y.-G, Selmer, M, Dunham, C.M, Weixlbaumer, A, Kelley, A.C, Ramakrishnan, V.
Deposit date:2009-09-01
Release date:2014-07-09
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:The structure of the ribosome with elongation factor G trapped in the posttranslocational state.
Science, 326, 2009
2VQF
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BU of 2vqf by Molmil
Modified uridines with C5-methylene substituents at the first position of the tRNA anticodon stabilize U-G wobble pairing during decoding
Descriptor: 16S RRNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ...
Authors:Kurata, S, Weixlbaumer, A, Ohtsuki, T, Shimazaki, T, Wada, T, Kirino, Y, Takai, K, Watanabe, K, Ramakrishnan, V, Suzuki, T.
Deposit date:2008-03-14
Release date:2008-04-29
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Modified Uridines with C5-Methylene Substituents at the First Position of the tRNA Anticodon Stabilize U.G Wobble Pairing During Decoding.
J.Biol.Chem., 283, 2008
2VQE
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BU of 2vqe by Molmil
Modified uridines with C5-methylene substituents at the first position of the tRNA anticodon stabilize U-G wobble pairing during decoding
Descriptor: 16S RRNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ...
Authors:Kurata, S, Weixlbaumer, A, Ohtsuki, T, Shimazaki, T, Wada, T, Kirino, Y, Takai, K, Watanabe, K, Ramakrishnan, V, Suzuki, T.
Deposit date:2008-03-13
Release date:2008-04-29
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Modified Uridines with C5-Methylene Substituents at the First Position of the tRNA Anticodon Stabilize U.G Wobble Pairing During Decoding.
J.Biol.Chem., 283, 2008
7PY0
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BU of 7py0 by Molmil
CryoEM structure of E.coli RNA polymerase elongation complex bound to NusG (NusG-EC in more-swiveled conformation)
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Zhu, C, Guo, X, Weixlbaumer, A.
Deposit date:2021-10-08
Release date:2022-03-23
Last modified:2022-10-05
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Transcription factors modulate RNA polymerase conformational equilibrium.
Nat Commun, 13, 2022
7PYJ
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BU of 7pyj by Molmil
CryoEM structure of E.coli RNA polymerase elongation complex bound to NusA (NusA elongation complex in less-swiveled conformation)
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Zhu, C, Guo, X, Weixlbaumer, A.
Deposit date:2021-10-10
Release date:2022-03-23
Last modified:2022-10-05
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Transcription factors modulate RNA polymerase conformational equilibrium.
Nat Commun, 13, 2022

 

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