Author results

6UE6
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PWWP1 DOMAIN OF NSD2 IN COMPLEX WITH MR837
Descriptor:Histone-lysine N-methyltransferase NSD2, 4-cyano-N-cyclopropyl-N-[(thiophen-2-yl)methyl]benzamide, UNKNOWN ATOM OR ION
Authors:Liu, Y., Tempel, W., De Freitas, R.F., Schapira, M., Brown, P.J., Bountra, C., Edwards, A.M., Arrowsmith, C.H., Min, J., Structural Genomics Consortium (SGC)
Deposit date:2019-09-20
Release date:2019-11-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:PWWP1 domain of NSD2 in complex with MR837
To Be Published
6J0D
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CRYSTAL STRUCTURE OF OSSUF4
Descriptor:transcription factor, ZINC ION
Authors:Wang, B., Luo, Q.
Deposit date:2018-12-24
Release date:2019-11-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The transcription factor OsSUF4 interacts with SDG725 in promoting H3K36me3 establishment.
Nat Commun, 10, 2019
6J6M
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CO-CRYSTAL STRUCTURE OF BTK KINASE DOMAIN WITH ZANUBRUTINIB
Descriptor:Tyrosine-protein kinase BTK, (7S)-2-(4-phenoxyphenyl)-7-(1-propanoylpiperidin-4-yl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide, IMIDAZOLE
Authors:Zhou, X., Hong, Y.
Deposit date:2019-01-15
Release date:2019-10-23
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Discovery of Zanubrutinib (BGB-3111), a Novel, Potent, and Selective Covalent Inhibitor of Bruton's Tyrosine Kinase.
J.Med.Chem., 62, 2019
6U84
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APO FULL-LENGTH RAT TRPV2 IN NANODISCS, STATE 1
Descriptor:Transient receptor potential cation channel subfamily V member 2
Authors:Pumroy, R.A., Moiseenkova-Bell, V.Y.
Deposit date:2019-09-04
Release date:2019-10-16
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Molecular mechanism of TRPV2 channel modulation by cannabidiol.
Elife, 8, 2019
6U86
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APO FULL-LENGTH RAT TRPV2 IN NANODISCS, STATE 2
Descriptor:Transient receptor potential cation channel subfamily V member 2
Authors:Pumroy, R.A., Moiseenkova-Bell, V.Y.
Deposit date:2019-09-04
Release date:2019-10-16
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Molecular mechanism of TRPV2 channel modulation by cannabidiol.
Elife, 8, 2019
6U88
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CBD-BOUND FULL-LENGTH RAT TRPV2 IN NANODISCS, STATE 2
Descriptor:Transient receptor potential cation channel subfamily V member 2, cannabidiol
Authors:Pumroy, R.A., Moiseenkova-Bell, V.Y.
Deposit date:2019-09-04
Release date:2019-10-16
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Molecular mechanism of TRPV2 channel modulation by cannabidiol.
Elife, 8, 2019
6U8A
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CBD-BOUND FULL-LENGTH RAT TRPV2 IN NANODISCS, STATE 1
Descriptor:Transient receptor potential cation channel subfamily V member 2, cannabidiol
Authors:Pumroy, R.A., Moiseenkova-Bell, V.Y.
Deposit date:2019-09-04
Release date:2019-10-16
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Molecular mechanism of TRPV2 channel modulation by cannabidiol.
Elife, 8, 2019
6ITX
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STRUCTURE OF THE C-TERMINAL HEAD DOMAIN OF THE AVIAN ADENOVIRUS EDSV FIBER
Descriptor:Fiber protein, GLUTAMINE, SULFATE ION
Authors:Wei, Q., Song, Y.
Deposit date:2018-11-26
Release date:2019-10-09
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Unravelling the receptor binding property of egg drop syndrome virus (EDSV) from the crystal structure of EDSV fiber head.
Int.J.Biol.Macromol., 139, 2019
6KUJ
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STRUCTURE OF INFLUENZA D VIRUS POLYMERASE BOUND TO CRNA PROMOTER IN CLASS 1
Descriptor:Polymerase 3, RNA-directed RNA polymerase catalytic subunit, Polymerase PB2, ...
Authors:Peng, Q., Peng, R., Qi, J., Gao, G.F., Shi, Y.
Deposit date:2019-09-02
Release date:2019-10-02
Last modified:2019-11-06
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structure of influenza D virus polymerase bound to cRNA promoter in Mode A conformation
NAT NANOTECHNOL, 2019
6KUK
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STRUCTURE OF INFLUENZA D VIRUS POLYMERASE BOUND TO VRNA PROMOTER IN MODE A CONFORMATION (CLASS A1)
Descriptor:Polymerase 3, RNA-directed RNA polymerase catalytic subunit, Polymerase PB2, ...
Authors:Peng, Q., Peng, R., Qi, J., Gao, G.F., Shi, Y.
Deposit date:2019-09-02
Release date:2019-10-02
Last modified:2019-11-06
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structure of influenza D virus polymerase bound to vRNA promoter in mode A conformation (class A1)
To Be Published
6KUP
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STRUCTURE OF INFLUENZA D VIRUS POLYMERASE BOUND TO VRNA PROMOTER IN MODE A CONFORMATION(CLASS A2)
Descriptor:Polymerase 3, RNA-directed RNA polymerase catalytic subunit, Polymerase PB2, ...
Authors:Peng, Q., Peng, R., Qi, J., Gao, G.F., Shi, Y.
Deposit date:2019-09-02
Release date:2019-10-02
Last modified:2019-11-06
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Structure of influenza D virus polymerase bound to vRNA promoter in Mode A conformation(Class A2)
To Be Published
6KUR
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STRUCTURE OF INFLUENZA D VIRUS POLYMERASE BOUND TO VRNA PROMOTER IN MODE B CONFORMATION (CLASS B1)
Descriptor:Polymerase 3, RNA-directed RNA polymerase catalytic subunit, Polymerase PB2, ...
Authors:Peng, Q., Peng, R., Qi, J., Gao, G.F., Shi, Y.
Deposit date:2019-09-02
Release date:2019-10-02
Last modified:2019-11-06
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structure of influenza D virus polymerase bound to vRNA promoter in Mode B conformation (Class B1)
To Be Published
6KUT
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STRUCTURE OF INFLUENZA D VIRUS POLYMERASE BOUND TO VRNA PROMOTER IN MODE B CONFORMATION (CLASS B2)
Descriptor:Polymerase 3, RNA-directed RNA polymerase catalytic subunit, Polymerase PB2, ...
Authors:Peng, Q., Peng, R., Qi, J., Gao, G.F., Shi, Y.
Deposit date:2019-09-02
Release date:2019-10-02
Last modified:2019-11-06
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:structure of influenza D virus apo polymerase
To Be Published
6KUV
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STRUCTURE OF INFLUENZA D VIRUS POLYMERASE BOUND TO CRNA PROMOTER IN CLASS 2
Descriptor:Polymerase 3, RNA-directed RNA polymerase catalytic subunit, Polymerase PB2, ...
Authors:Peng, Q., Peng, R., Qi, J., Gao, G.F., Shi, Y.
Deposit date:2019-09-02
Release date:2019-10-02
Last modified:2019-11-06
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structure of influenza D virus polymerase bound to cRNA promoter in Mode B conformation
To Be Published
6KV5
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STRUCTURE OF INFLUENZA D VIRUS APO POLYMERASE
Descriptor:Polymerase 3, RNA-directed RNA polymerase catalytic subunit, Polymerase PB2
Authors:Peng, Q., Peng, R., Qi, J., Gao, G.F., Shi, Y.
Deposit date:2019-09-03
Release date:2019-10-02
Last modified:2019-11-06
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Structure of influenza D virus apo polymerase
To be published
6OJ0
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CRYO-EM RECONSTRUCTION OF SULFOLOBUS POLYHEDRAL VIRUS 1 (SPV1)
Descriptor:Structural protein VP4, Uncharacterized protein
Authors:Wang, F., Liu, Y., Conway, J.F., Krupovic, M., Prangishvili, D., Egelman, E.H.
Deposit date:2019-04-10
Release date:2019-10-02
Last modified:2019-11-06
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:A packing for A-form DNA in an icosahedral virus.
Proc.Natl.Acad.Sci.USA, 2019
6U95
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ADENO-ASSOCIATED VIRUS STRAIN AAVHU.37 CAPSID ICOSAHEDRAL STRUCTURE
Descriptor:Capsid protein VP1
Authors:Kaelber, J.T., Yost, S.A., Firlar, E., Mercer, A.C.
Deposit date:2019-09-06
Release date:2019-09-18
Method:ELECTRON MICROSCOPY (2.56 Å)
Cite:Structure of the AAVhu.37 capsid by cryoelectron microscopy
To Be Published
6J2P
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CRYSTAL STRUCTURE OF SACCHAROMYCES CEREVISIAE SPP1 IN COMPLEX WITH H3K4ME3
Descriptor:COMPASS component SPP1, Histone H3, ZINC ION
Authors:He, C., Li, F.
Deposit date:2019-01-02
Release date:2019-09-11
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structural basis for histone H3K4me3 recognition by the N-terminal domain of the PHD finger protein Spp1.
Biochem.J., 476, 2019
6ABO
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HUMAN XRCC4 AND IFFO1 COMPLEX
Descriptor:DNA repair protein XRCC4, Intermediate filament family orphan 1, GLYCEROL, ...
Authors:Li, J., Liu, L., Liang, H., Liu, Y., Xu, D.
Deposit date:2018-07-23
Release date:2019-07-31
Last modified:2019-10-16
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:The nucleoskeleton protein IFFO1 immobilizes broken DNA and suppresses chromosome translocation during tumorigenesis.
Nat.Cell Biol., 21, 2019
6CXC
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3.9A CRYO-EM STRUCTURE OF MURINE ANTIBODY BOUND AT A NOVEL EPITOPE OF RESPIRATORY SYNCYTIAL VIRUS FUSION PROTEIN
Descriptor:R4.C6 Fab Heavy Chain, R4.C6 Fab Light Chain, Fusion glycoprotein F0, ...
Authors:Xie, Q., Wang, Z., Chen, X., Ni, F., Ma, J., Wang, Q.
Deposit date:2018-04-02
Release date:2019-07-31
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Near-atomic structure of a novel site II/IV antigenic epitope on respiratory syncytial virus fusion glycoprotein determined by cryo-EM
To be Published
6CV1
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CRYOEM STRUCTURE OF HUMAN ENTEROVIRUS D68 FULL PARTICLE (AFTER INCUBATION WITH HEPARIN-DERIVED HEXASACCHARIDE)
Descriptor:viral protein 1, viral protein 3, viral protein 2, ...
Authors:Liu, Y., Rossmann, M.G.
Deposit date:2018-03-27
Release date:2019-07-24
Last modified:2019-07-31
Method:ELECTRON MICROSCOPY (2.76 Å)
Cite:Bypassing pan-enterovirus host factor PLA2G16.
Nat Commun, 10, 2019
6CV2
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CRYOEM STRUCTURE OF HUMAN ENTEROVIRUS D68 FULL VIRION
Descriptor:viral protein 1, viral protein 3, viral protein 2, ...
Authors:Liu, Y., Rossmann, M.G.
Deposit date:2018-03-27
Release date:2019-07-24
Last modified:2019-07-31
Method:ELECTRON MICROSCOPY (2.86 Å)
Cite:Bypassing pan-enterovirus host factor PLA2G16.
Nat Commun, 10, 2019
6CV3
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CRYOEM STRUCTURE OF HUMAN ENTEROVIRUS D68 EMPTIED PARTICLE
Descriptor:viral protein 1, viral protein 3, viral protein 2
Authors:Liu, Y., Rossmann, M.G.
Deposit date:2018-03-27
Release date:2019-07-24
Last modified:2019-07-31
Method:ELECTRON MICROSCOPY (3.56 Å)
Cite:Bypassing pan-enterovirus host factor PLA2G16.
Nat Commun, 10, 2019
6CV4
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CRYOEM STRUCTURE OF HUMAN ENTEROVIRUS D68 EMPTIED PARTICLE (AFTER INCUBATION WITH LOW MOLECULAR WEIGHT HEPARIN)
Descriptor:viral protein 1, viral protein 3, viral protein 2
Authors:Liu, Y., Rossmann, M.G.
Deposit date:2018-03-27
Release date:2019-07-24
Last modified:2019-07-31
Method:ELECTRON MICROSCOPY (3.03 Å)
Cite:Bypassing pan-enterovirus host factor PLA2G16.
Nat Commun, 10, 2019
6CV5
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CRYOEM STRUCTURE OF HUMAN ENTEROVIRUS D68 FULL PARTICLE (AFTER INCUBATION WITH LOW MOLECULAR WEIGHT HEPARIN)
Descriptor:viral protein 1, viral protein 3, viral protein 2, ...
Authors:Liu, Y., Rossmann, M.G.
Deposit date:2018-03-27
Release date:2019-07-24
Last modified:2019-07-31
Method:ELECTRON MICROSCOPY (2.79 Å)
Cite:Bypassing pan-enterovirus host factor PLA2G16.
Nat Commun, 10, 2019