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1SEB
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BU of 1seb by Molmil
COMPLEX OF THE HUMAN MHC CLASS II GLYCOPROTEIN HLA-DR1 AND THE BACTERIAL SUPERANTIGEN SEB
Descriptor: ENDOGENOUS PEPTIDE MODEL, POLY-ALA, ENTEROTOXIN TYPE B, ...
Authors:Jardetzky, T.S, Brown, J.H, Gorga, J.C, Stern, L.J, Urban, R.G, Chi, Y.I, Stauffacher, C, Strominger, J.L, Wiley, D.C.
Deposit date:1995-11-26
Release date:1996-06-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Three-dimensional structure of a human class II histocompatibility molecule complexed with superantigen.
Nature, 368, 1994
3MAW
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BU of 3maw by Molmil
Structure of the Newcastle disease virus F protein in the post-fusion conformation
Descriptor: 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0
Authors:Jardetzky, T.S, Wen, X.
Deposit date:2010-03-24
Release date:2010-05-26
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structure of the Newcastle disease virus F protein in the post-fusion conformation.
Virology, 402, 2010
4DAG
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BU of 4dag by Molmil
Structure of the Human Metapneumovirus Fusion Protein with Neutralizing Antibody Identifies a Pneumovirus Antigenic Site
Descriptor: Fusion glycoprotein F0, Neutralizing Antibody DS7 heavy chain, Neutralizing Antibody DS7 light chain, ...
Authors:Jardetzky, T.S, Wen, X.
Deposit date:2012-01-12
Release date:2012-02-29
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.3904 Å)
Cite:Structure of the human metapneumovirus fusion protein with neutralizing antibody identifies a pneumovirus antigenic site.
Nat.Struct.Mol.Biol., 19, 2012
4WSG
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BU of 4wsg by Molmil
Crystal Structure of Soluble WR PIV5 F-GCNt
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0
Authors:Poor, T.A, Song, A.S, Welch, B.D, Kors, C.A, Jardetzky, T.S, Lamb, R.A.
Deposit date:2014-10-27
Release date:2015-01-21
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal Structure of Soluble WR PIV5 F-GCNt
J.Virol., 89, 2015
6UQR
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BU of 6uqr by Molmil
Complex of IgE and Ligelizumab
Descriptor: IgE, Ligelizumab, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Tarchevskaya, S.S, Kleinboelting, S, Jardetzky, T.S.
Deposit date:2019-10-21
Release date:2019-12-04
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.6502912 Å)
Cite:The mechanistic and functional profile of the therapeutic anti-IgE antibody ligelizumab differs from omalizumab.
Nat Commun, 11, 2020
2P6A
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BU of 2p6a by Molmil
The structure of the Activin:Follistatin 315 complex
Descriptor: Follistatin, Inhibin beta A chain, probable fragment of follistatin
Authors:Lerch, T.F, Shimasaki, S, Woodruff, T.K, Jardetzky, T.S.
Deposit date:2007-03-16
Release date:2007-04-03
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structural and biophysical coupling of heparin and activin binding to follistatin isoform functions.
J.Biol.Chem., 282, 2007
5EJB
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BU of 5ejb by Molmil
Crystal structure of prefusion Hendra virus F protein
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0, ...
Authors:Wong, J.W, Jardetzky, T.S, Paterson, R.G, Lamb, R.A.
Deposit date:2015-11-01
Release date:2016-01-06
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structure and stabilization of the Hendra virus F glycoprotein in its prefusion form.
Proc.Natl.Acad.Sci.USA, 113, 2016
8EAY
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BU of 8eay by Molmil
HMPV F complex with 4I3 Fab
Descriptor: 4I3 heavy chain protein, 4I3 light chain protein, Fusion glycoprotein F0
Authors:Wen, X, Jardetzky, T.S.
Deposit date:2022-08-30
Release date:2023-08-16
Last modified:2023-08-23
Method:ELECTRON MICROSCOPY (3.33 Å)
Cite:Potent cross-neutralization of respiratory syncytial virus and human metapneumovirus through a structurally conserved antibody recognition mode.
Cell Host Microbe, 31, 2023
8E2U
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BU of 8e2u by Molmil
HMPV F monomer bound to RSV-199 Fab
Descriptor: Fusion glycoprotein F0, RSV-199 heavy chain, RSV-199 light chain
Authors:Wen, X, Jardetzky, T.S.
Deposit date:2022-08-16
Release date:2023-08-16
Last modified:2023-08-23
Method:ELECTRON MICROSCOPY (3.48 Å)
Cite:Potent cross-neutralization of respiratory syncytial virus and human metapneumovirus through a structurally conserved antibody recognition mode.
Cell Host Microbe, 31, 2023
8DZW
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BU of 8dzw by Molmil
RSV F trimer bound to RSV-199 Fab
Descriptor: RSV fusion protein, RSV-199 Heavy chain protein, RSV-199 Light chain protein
Authors:Wen, X, Jardetzky, T.S.
Deposit date:2022-08-08
Release date:2023-08-16
Last modified:2023-08-23
Method:ELECTRON MICROSCOPY (2.46 Å)
Cite:Potent cross-neutralization of respiratory syncytial virus and human metapneumovirus through a structurally conserved antibody recognition mode.
Cell Host Microbe, 31, 2023
8EBP
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BU of 8ebp by Molmil
HMPV F dimer bound to RSV-199 Fab
Descriptor: Fusion glycoprotein F0, RSV-199 heavy chain protein, RSV-199 light chain protein
Authors:Wen, X, Jardetzky, T.S.
Deposit date:2022-08-31
Release date:2023-08-16
Last modified:2023-08-23
Method:ELECTRON MICROSCOPY (3.38 Å)
Cite:Potent cross-neutralization of respiratory syncytial virus and human metapneumovirus through a structurally conserved antibody recognition mode.
Cell Host Microbe, 31, 2023
3PHF
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BU of 3phf by Molmil
Crystal Structure of the Epstein-Barr virus gH and gL complex
Descriptor: Envelope glycoprotein H, Envelope glycoprotein L
Authors:Matsuura, H, Kirschner, A.N, Jardetzky, T.S.
Deposit date:2010-11-04
Release date:2011-01-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.58 Å)
Cite:Crystal structure of the Epstein-Barr virus (EBV) glycoprotein H/glycoprotein L (gH/gL) complex.
Proc.Natl.Acad.Sci.USA, 107, 2010
3QW9
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BU of 3qw9 by Molmil
Crystal structure of betaglycan ZP-C domain
Descriptor: Transforming growth factor beta receptor type 3, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)][alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)][alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Lin, S.J, Jardetzky, T.S.
Deposit date:2011-02-27
Release date:2011-04-06
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of betaglycan zona pellucida (ZP)-C domain provides insights into ZP-mediated protein polymerization and TGF-{beta} binding.
Proc.Natl.Acad.Sci.USA, 108, 2011
3T1E
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BU of 3t1e by Molmil
The structure of the Newcastle disease virus hemagglutinin-neuraminidase (HN) ectodomain reveals a 4-helix bundle stalk
Descriptor: Hemagglutinin-neuraminidase
Authors:Yuan, P, Swanson, K, Leser, G.P, Paterson, R.G, Lamb, R.A, Jardetzky, T.S.
Deposit date:2011-07-21
Release date:2011-09-07
Last modified:2011-09-21
Method:X-RAY DIFFRACTION (3.301 Å)
Cite:Structure of the Newcastle disease virus hemagglutinin-neuraminidase (HN) ectodomain reveals a four-helix bundle stalk.
Proc.Natl.Acad.Sci.USA, 108, 2011
3TSI
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BU of 3tsi by Molmil
Structure of the parainfluenza virus 5 (PIV5) hemagglutinin-neuraminidase (HN) stalk domain
Descriptor: Hemagglutinin-neuraminidase
Authors:Bose, S, Welch, B.D, Kors, C.A, Yuan, P, Jardetzky, T.S, Lamb, R.A.
Deposit date:2011-09-13
Release date:2011-10-26
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.651 Å)
Cite:Structure and mutagenesis of the parainfluenza virus 5 hemagglutinin-neuraminidase stalk domain reveals a four-helix bundle and the role of the stalk in fusion promotion.
J.Virol., 85, 2011
5T1D
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BU of 5t1d by Molmil
Crystal structure of EBV gHgL/gp42/E1D1 complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, E1D1 IgG2a heavy chain, E1D1 IgG2a light chain, ...
Authors:Sathiyamoorthy, K, Jardetzky, T.S.
Deposit date:2016-08-18
Release date:2016-12-28
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural basis for Epstein-Barr virus host cell tropism mediated by gp42 and gHgL entry glycoproteins.
Nat Commun, 7, 2016
5U68
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BU of 5u68 by Molmil
Structural basis for antibody cross-neutralization of respiratory syncytial virus and human metapneumovirus
Descriptor: Chimera protein of Fusion glycoprotein F0 and Envelope glycoprotein, MPE8
Authors:Wen, X, Jardetzky, T.S.
Deposit date:2016-12-07
Release date:2017-02-15
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.083 Å)
Cite:Structural basis for antibody cross-neutralization of respiratory syncytial virus and human metapneumovirus.
Nat Microbiol, 2, 2017
5W0K
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BU of 5w0k by Molmil
Crystal structure of EBV gHgL/CL40/gp42 N-domain
Descriptor: CL40 IgG heavy chain, CL40 IgG light chain, Envelope glycoprotein H, ...
Authors:Sathiyamoorthy, K, Jardetzky, T.S.
Deposit date:2017-05-31
Release date:2017-10-04
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Inhibition of EBV-mediated membrane fusion by anti-gHgL antibodies.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5HYS
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BU of 5hys by Molmil
Structure of IgE complexed with omalizumab
Descriptor: Epididymis luminal protein 214, Ig epsilon chain C region, SULFATE ION, ...
Authors:Pennington, L.F, Tarchevskaya, S.S, Sathiyamoorthy, K, Jardetzky, T.S.
Deposit date:2016-02-01
Release date:2016-06-01
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis of omalizumab therapy and omalizumab-mediated IgE exchange.
Nat Commun, 7, 2016
7RAM
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BU of 7ram by Molmil
Cryo-EM Structure of the HCMV gHgLgO Trimer Derived from AD169 and TR strains in complex with PDGFRalpha
Descriptor: Envelope glycoprotein H, Envelope glycoprotein L, Envelope glycoprotein O, ...
Authors:Liu, J, Vanarsdall, A.L, Chen, D, Johnson, D.C, Jardetzky, T.S.
Deposit date:2021-07-02
Release date:2022-06-08
Method:ELECTRON MICROSCOPY (3.43 Å)
Cite:Cryo-Electron Microscopy Structure and Interactions of the Human Cytomegalovirus gHgLgO Trimer with Platelet-Derived Growth Factor Receptor Alpha.
Mbio, 12, 2021
4FZH
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BU of 4fzh by Molmil
Structure of the Ulster Strain Newcastle Disease Virus Hemagglutinin-Neuraminidase Reveals Auto-Inhibitory Interactions Associated with Low Virulence
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin-neuraminidase
Authors:Yuan, P, Paterson, R.G, Leser, G.P, Lamb, R.A, Jardetzky, T.S.
Deposit date:2012-07-06
Release date:2012-09-05
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.5008 Å)
Cite:Structure of the ulster strain newcastle disease virus hemagglutinin-neuraminidase reveals auto-inhibitory interactions associated with low virulence.
Plos Pathog., 8, 2012
4GIP
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BU of 4gip by Molmil
Structure of the cleavage-activated prefusion form of the parainfluenza virus 5 (PIV5) fusion protein
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F1, Fusion glycoprotein F2
Authors:Welch, B.D, Liu, Y, Kors, C.A, Leser, G.P, Jardetzky, T.S, Lamb, R.A.
Deposit date:2012-08-08
Release date:2012-09-19
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of the cleavage-activated prefusion form of the parainfluenza virus 5 fusion protein.
Proc.Natl.Acad.Sci.USA, 109, 2012
4GRG
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BU of 4grg by Molmil
Crystal structure of IgE complexed with E2_79, an anti-IgE inhibitor
Descriptor: ANTI-IGE INHIBITOR E2_79, Ig epsilon chain C region
Authors:Kim, B, Jardetzky, T.S.
Deposit date:2012-08-24
Release date:2012-12-12
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (4.24 Å)
Cite:Accelerated disassembly of IgE-receptor complexes by a disruptive macromolecular inhibitor.
Nature, 491, 2012
4GT7
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BU of 4gt7 by Molmil
An engineered disulfide bond reversibly traps the IgE-Fc3-4 in a closed, non-receptor binding conformation
Descriptor: Ig epsilon chain C region, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Wurzburg, B.A, Kim, B.K, Jardetzky, T.S.
Deposit date:2012-08-28
Release date:2012-09-12
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.61 Å)
Cite:An engineered disulfide bond reversibly traps the IgE-Fc3-4 in a closed, nonreceptor binding conformation.
J.Biol.Chem., 287, 2012
4JF7
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BU of 4jf7 by Molmil
Structure of the parainfluenza virus 5 (PIV5) hemagglutinin-neuraminidase (HN) ectodomain
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Welch, B.D, Yuan, P, Bose, S, Kors, C.A, Lamb, R.A, Jardetzky, T.S.
Deposit date:2013-02-27
Release date:2013-09-04
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.5018 Å)
Cite:Structure of the Parainfluenza Virus 5 (PIV5) Hemagglutinin-Neuraminidase (HN) Ectodomain.
Plos Pathog., 9, 2013

 

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