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1HFI
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BU of 1hfi by Molmil
SOLUTION STRUCTURE OF A PAIR OF COMPLEMENT MODULES BY NUCLEAR MAGNETIC RESONANCE
Descriptor: FACTOR H, 15TH C-MODULE PAIR
Authors:Barlow, P.N, Steinkasserer, A, Norman, D.G, Kieffer, B, Wiles, A.P, Sim, R.B, Campbell, I.D.
Deposit date:1993-02-23
Release date:1993-07-15
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Solution structure of a pair of complement modules by nuclear magnetic resonance.
J.Mol.Biol., 232, 1993
1CHC
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BU of 1chc by Molmil
STRUCTURE OF THE C3HC4 DOMAIN BY 1H-NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; A NEW STRUCTURAL CLASS OF ZINC-FINGER
Descriptor: EQUINE HERPES VIRUS-1 RING DOMAIN, ZINC ION
Authors:Barlow, P.N, Everett, R.D, Luisi, B.
Deposit date:1994-02-02
Release date:1994-04-30
Last modified:2022-02-16
Method:SOLUTION NMR
Cite:Structure of the C3HC4 domain by 1H-nuclear magnetic resonance spectroscopy. A new structural class of zinc-finger.
J.Mol.Biol., 237, 1994
1HFH
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BU of 1hfh by Molmil
SOLUTION STRUCTURE OF A PAIR OF COMPLEMENT MODULES BY NUCLEAR MAGNETIC RESONANCE
Descriptor: FACTOR H, 15TH AND 16TH C-MODULE PAIR
Authors:Barlow, P.N, Steinkasserer, A, Norman, D.G, Kieffer, B, Wiles, A.P, Sim, R.B, Campbell, I.D.
Deposit date:1993-02-23
Release date:1993-07-15
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Solution structure of a pair of complement modules by nuclear magnetic resonance.
J.Mol.Biol., 232, 1993
2WCY
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BU of 2wcy by Molmil
NMR solution structure of factor I-like modules of complement C7.
Descriptor: COMPLEMENT COMPONENT C7
Authors:Phelan, M.M, Thai, C.T, Soares, D.C, Ogata, R.T, Barlow, P.N, Bramham, J.
Deposit date:2009-03-17
Release date:2009-05-19
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Solution Structure of Factor I-Like Modules from Complement C7 Reveals a Pair of Follistatin Domains in Compact Pseudosymmetric Arrangement.
J.Biol.Chem., 284, 2009
1B3A
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BU of 1b3a by Molmil
TOTAL CHEMICAL SYNTHESIS AND HIGH-RESOLUTION CRYSTAL STRUCTURE OF THE POTENT ANTI-HIV PROTEIN AOP-RANTES
Descriptor: PENTYLOXYAMINO-ACETALDEHYDE, PROTEIN (RANTES), SULFATE ION
Authors:Wilken, J, Hoover, D, Thompson, D.A, Barlow, P.N, Mcsparron, H, Picard, L, Wlodawer, A, Lubkowski, J, Kent, S.B.H.
Deposit date:1998-12-07
Release date:1999-04-23
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Total chemical synthesis and high-resolution crystal structure of the potent anti-HIV protein AOP-RANTES.
Chem.Biol., 6, 1999
2V8E
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BU of 2v8e by Molmil
Crystal structure of Human Complement Factor H, SCR domains 6-8 (H402 risk variant), in complex with ligand.
Descriptor: 1,3,4,6-tetra-O-sulfo-beta-D-fructofuranose-(2-1)-2,3,4,6-tetra-O-sulfonato-alpha-D-glucopyranose, CHLORIDE ION, COMPLEMENT FACTOR H, ...
Authors:Prosser, B.E, Johnson, S, Roversi, P, Herbert, A.P, Blaum, B.S, Tyrrell, J, Jowitt, T.A, Clark, S.J, Tarelli, E, Uhrin, D, Barlow, P.N, Sim, R.B, Day, A.J, Lea, S.M.
Deposit date:2007-08-07
Release date:2007-10-02
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Basis for Complement Factor H Linked Age-Related Macular Degeneration.
J.Exp.Med., 204, 2007
3SW0
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BU of 3sw0 by Molmil
Structure of the C-terminal region (modules 18-20) of complement regulator Factor H
Descriptor: Complement factor H, GLYCEROL, PHOSPHATE ION
Authors:Morgan, H.P, Guariento, M, Schmidt, C.Q, Barlow, P.N, Hannan, J.P.
Deposit date:2011-07-13
Release date:2012-03-14
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural Analysis of the C-Terminal Region (Modules 18-20) of Complement Regulator Factor H (FH).
Plos One, 7, 2012
1Z1M
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BU of 1z1m by Molmil
NMR structure of unliganded MDM2
Descriptor: Ubiquitin-protein ligase E3 Mdm2
Authors:Uhrinova, S, Uhrin, D, Powers, H, Watt, K, Zheleva, D, Fischer, P, McInnes, C, Barlow, P.N.
Deposit date:2005-03-04
Release date:2005-06-28
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:Structure of Free MDM2 N-terminal Domain Reveals Conformational Adjustments that Accompany p53-binding
J.Mol.Biol., 350, 2005
2A55
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BU of 2a55 by Molmil
Solution structure of the two N-terminal CCP modules of C4b-binding protein (C4BP) alpha-chain.
Descriptor: C4b-binding protein
Authors:Jenkins, H.T, Mark, L, Ball, G, Lindahl, G, Uhrin, D, Blom, A.M, Barlow, P.N.
Deposit date:2005-06-30
Release date:2005-12-13
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:Human C4b-binding Protein, Structural Basis for Interaction with Streptococcal M Protein, a Major Bacterial Virulence Factor
J.Biol.Chem., 281, 2006
2BZM
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BU of 2bzm by Molmil
Solution structure of the primary host recognition region of complement factor H
Descriptor: COMPLEMENT FACTOR H
Authors:Herbert, A.P, Uhrin, D, Lyon, M, Pangburn, M.K, Barlow, P.N.
Deposit date:2005-08-18
Release date:2006-03-22
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Disease-Associated Sequence Variations Congregate in a Polyanion Recognition Patch on Human Factor H Revealed in Three-Dimensional Structure.
J.Biol.Chem., 281, 2006
3OXU
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BU of 3oxu by Molmil
Complement components factor H CCP19-20 and C3d in complex
Descriptor: Complement C3, GLYCEROL, HF protein
Authors:Morgan, H.P, Schmidt, C.Q, Guariento, M, Gillespie, D, Herbert, A.P, Mertens, H, Blaum, B.S, Svergun, D, Johansson, C.M, Uhrin, D, Barlow, P.N, Hannan, J.P.
Deposit date:2010-09-22
Release date:2011-02-16
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis for engagement by complement factor H of C3b on a self surface.
Nat.Struct.Mol.Biol., 18, 2011
3R62
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BU of 3r62 by Molmil
Structure of complement regulator Factor H mutant, T1184R.
Descriptor: Complement factor H, GLYCEROL
Authors:Morgan, H.P, Jiang, J, Herbert, A.P, Kavanagh, D, Uhran, D, Barlow, P.N, Hannan, J.P.
Deposit date:2011-03-21
Release date:2011-06-29
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.52 Å)
Cite:Crystallographic determination of the disease-associated T1184R variant of the complement Factor H.
Acta Crystallogr.,Sect.D, 67, 2011
1DV9
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BU of 1dv9 by Molmil
STRUCTURAL CHANGES ACCOMPANYING PH-INDUCED DISSOCIATION OF THE B-LACTOGLOBULIN DIMER
Descriptor: BETA-LACTOGLOBULIN
Authors:Uhrinova, S, Smith, M.H, Jameson, G.B, Uhrin, D, Sawyer, L, Barlow, P.N.
Deposit date:2000-01-20
Release date:2000-02-09
Last modified:2022-02-16
Method:SOLUTION NMR
Cite:Structural changes accompanying pH-induced dissociation of the beta-lactoglobulin dimer.
Biochemistry, 39, 2000
1H67
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BU of 1h67 by Molmil
NMR Structure of the CH Domain of Calponin
Descriptor: CALPONIN ALPHA
Authors:Bramham, J, Smith, B.O, Uhrin, D, Barlow, P.N, Winder, S.J.
Deposit date:2001-06-07
Release date:2002-02-14
Last modified:2020-01-15
Method:SOLUTION NMR
Cite:Solution Structure of the Calponin Ch Domain and Fitting to the 3D-Helical Reconstruction of F-Actin:Calponin.
Structure, 10, 2002
2JGX
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BU of 2jgx by Molmil
Structure of CCP module 7 of complement factor H - The AMD Not at risk varient (402Y)
Descriptor: COMPLEMENT FACTOR H
Authors:Herbert, A.P, Deakin, J.A, Schmidt, C.Q, Blaum, B.S, Egan, C, Ferreira, V.P, Pangburn, M.K, Lyon, M, Uhrin, D, Barlow, P.N.
Deposit date:2007-02-16
Release date:2007-03-20
Last modified:2018-05-02
Method:SOLUTION NMR
Cite:Structure shows that a glycosaminoglycan and protein recognition site in factor H is perturbed by age-related macular degeneration-linked single nucleotide polymorphism.
J. Biol. Chem., 282, 2007
2JGW
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BU of 2jgw by Molmil
Structure of CCP module 7 of complement factor H - The AMD at risk varient (402H)
Descriptor: COMPLEMENT FACTOR H
Authors:Herbert, A.P, Deakin, J.A, Schmidt, C.Q, Blaum, B.S, Egan, C, Ferreira, V.P, Pangburn, M.K, Lyon, M, Uhrin, D, Barlow, P.N.
Deposit date:2007-02-16
Release date:2007-03-20
Last modified:2018-05-02
Method:SOLUTION NMR
Cite:Structure shows that a glycosaminoglycan and protein recognition site in factor H is perturbed by age-related macular degeneration-linked single nucleotide polymorphism.
J. Biol. Chem., 282, 2007
2KMS
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BU of 2kms by Molmil
Combined high- and low-resolution techniques reveal compact structure in central portion of factor H despite long inter-modular linkers
Descriptor: Complement factor H
Authors:Schmidt, C.Q, Herbert, A.P, Guariento, M, Mertens, H.D.T, Soares, D.C, Uhrin, D, Rowe, A.J, Svergun, D.I, Barlow, P.N.
Deposit date:2009-08-04
Release date:2009-11-03
Last modified:2020-02-26
Method:SOLUTION NMR
Cite:The Central Portion of Factor H (Modules 10-15) Is Compact and Contains a Structurally Deviant CCP Module
J.Mol.Biol., 395, 2010
2MCZ
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BU of 2mcz by Molmil
CR1 Sushi domains 1 and 2
Descriptor: Complement receptor type 1
Authors:Park, H.J, Guariento, M.J, Maciejewski, M, Hauart, R, Tham, W, Cowman, A.F, Schmidt, C.Q, Martens, H, Liszewski, K.M, Hourcade, D, Barlow, P.N, Atkinson, J.P.
Deposit date:2013-08-27
Release date:2013-11-13
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Using Mutagenesis and Structural Biology to Map the Binding Site for the Plasmodium falciparum Merozoite Protein PfRh4 on the Human Immune Adherence Receptor.
J.Biol.Chem., 289, 2014
2MCY
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BU of 2mcy by Molmil
CR1 Sushi domains 2 and 3
Descriptor: Complement receptor type 1
Authors:Park, H.J, Guariento, M.J, Maciejewski, M, Hauart, R, Tham, W, Cowman, A.F, Schmidt, C.Q, Martens, H, Liszewski, K.M, Hourcade, D, Barlow, P.N, Atkinson, J.P.
Deposit date:2013-08-27
Release date:2013-11-13
Last modified:2014-01-22
Method:SOLUTION NMR
Cite:Using Mutagenesis and Structural Biology to Map the Binding Site for the Plasmodium falciparum Merozoite Protein PfRh4 on the Human Immune Adherence Receptor.
J.Biol.Chem., 289, 2014
2RLQ
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BU of 2rlq by Molmil
NMR structure of CCP modules 2-3 of complement factor H
Descriptor: Complement factor H
Authors:Hocking, H.G, Herbert, A.P, Pangburn, M.K, Kavanagh, D, Barlow, P.N, Uhrin, D.
Deposit date:2007-07-29
Release date:2008-02-19
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:Structure of the N-terminal region of complement factor H and conformational implications of disease-linked sequence variations.
J.Biol.Chem., 283, 2008
2RLP
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BU of 2rlp by Molmil
NMR structure of CCP modules 1-2 of complement factor H
Descriptor: Complement factor H
Authors:Hocking, H.G, Herbert, A.P, Pangburn, M.K, Kavanagh, D, Barlow, P.N, Uhrin, D.
Deposit date:2007-07-28
Release date:2008-02-19
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:Structure of the N-terminal region of complement factor H and conformational implications of disease-linked sequence variations.
J.Biol.Chem., 283, 2008
2UWN
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BU of 2uwn by Molmil
Crystal structure of Human Complement Factor H, SCR domains 6-8 (H402 risk variant), in complex with ligand.
Descriptor: 1,3,4,6-tetra-O-sulfo-beta-D-fructofuranose-(2-1)-2,3,4,6-tetra-O-sulfonato-alpha-D-glucopyranose, ACETATE ION, CHLORIDE ION, ...
Authors:Prosser, B.E, Johnson, S, Roversi, P, Herbert, A.P, Blaum, B.S, Tyrrell, J, Jowitt, T.A, Clark, S.J, Terelli, E, Uhrin, D, Barlow, P.N, Sim, R.B, Day, A.J, Lea, S.M.
Deposit date:2007-03-22
Release date:2007-10-02
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural Basis for Complement Factor H Linked Age-Related Macular Degeneration.
J.Exp.Med., 204, 2007
1NWV
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BU of 1nwv by Molmil
SOLUTION STRUCTURE OF A FUNCTIONALLY ACTIVE COMPONENT OF DECAY ACCELERATING FACTOR
Descriptor: Complement decay-accelerating factor
Authors:Uhrinova, S, Lin, F, Ball, G, Bromek, K, Uhrin, D, Medof, M.E, Barlow, P.N.
Deposit date:2003-02-07
Release date:2003-04-22
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Solution structure of a functionally active fragment of decay-accelerating factor
Proc.Natl.Acad.Sci.USA, 100, 2003
1E5G
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BU of 1e5g by Molmil
Solution structure of central CP module pair of a pox virus complement inhibitor
Descriptor: COMPLEMENT CONTROL PROTEIN C3
Authors:Henderson, C.E, Bromek, K, Mullin, N.P, Smith, B.O, Uhrin, D, Barlow, P.N.
Deposit date:2000-07-25
Release date:2000-08-31
Last modified:2013-07-03
Method:SOLUTION NMR
Cite:Solution Structure and Dynamics of the Central Ccp Module Pair of a Poxvirus Complement Control Protein
J.Mol.Biol., 307, 2001
1PPQ
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BU of 1ppq by Molmil
NMR structure of 16th module of Immune Adherence Receptor, Cr1 (Cd35)
Descriptor: Complement receptor type 1
Authors:O'Leary, J.M, Bromek, K, Black, G.M, Uhrinova, S, Schmitz, C, Krych, M, Atkinson, J.P, Uhrin, D, Barlow, P.N.
Deposit date:2003-06-17
Release date:2004-05-04
Last modified:2021-10-27
Method:SOLUTION NMR
Cite:Backbone dynamics of complement control protein (CCP) modules reveals mobility in binding surfaces.
Protein Sci., 13, 2004

 

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