4L1H
 
 | |
1AR2
 | | DISULFIDE-FREE IMMUNOGLOBULIN FRAGMENT | | Descriptor: | REI | | Authors: | Uson, I, Bes, M.T, Sheldrick, G.M, Schneider, T.R, Hartsch, T, Fritz, H.-J. | | Deposit date: | 1997-08-08 | | Release date: | 1997-11-12 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | X-ray crystallography reveals stringent conservation of protein fold after removal of the only disulfide bridge from a stabilized immunoglobulin variable domain.
Structure Fold.Des., 2, 1997
|
|
1BX8
 | | HIRUSTASIN FROM HIRUDO MEDICINALIS AT 1.4 ANGSTROMS | | Descriptor: | HIRUSTASIN, SULFATE ION | | Authors: | Uson, I, Sheldrick, G.M, De La Fortelle, E, Bricogne, G, Di Marco, S, Priestle, J.P, Gruetter, M.G, Mittl, P.R.E. | | Deposit date: | 1998-10-14 | | Release date: | 1999-04-27 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | The 1.2 A crystal structure of hirustasin reveals the intrinsic flexibility of a family of highly disulphide-bridged inhibitors.
Structure Fold.Des., 7, 1999
|
|
1BX7
 | | HIRUSTASIN FROM HIRUDO MEDICINALIS AT 1.2 ANGSTROMS | | Descriptor: | HIRUSTASIN, SULFATE ION | | Authors: | Uson, I, Sheldrick, G.M, De La Fortelle, E, Bricogne, G, Di Marco, S, Priestle, J.P, Gruetter, M.G, Mittl, P.R.E. | | Deposit date: | 1998-10-14 | | Release date: | 1999-04-27 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (1.2 Å) | | Cite: | The 1.2 A crystal structure of hirustasin reveals the intrinsic flexibility of a family of highly disulphide-bridged inhibitors.
Structure Fold.Des., 7, 1999
|
|
1BWW
 | | BENCE-JONES IMMUNOGLOBULIN REI VARIABLE PORTION, T39K MUTANT | | Descriptor: | PROTEIN (IG KAPPA CHAIN V-I REGION REI) | | Authors: | Uson, I, Pohl, E, Schneider, T.R, Dauter, Z, Schmidt, A, Fritz, H.J, Sheldrick, G.M. | | Deposit date: | 1998-09-29 | | Release date: | 1998-10-07 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | 1.7 A structure of the stabilized REIv mutant T39K. Application of local NCS restraints.
Acta Crystallogr.,Sect.D, 55, 1999
|
|
4AEQ
 | | Crystal structure of the dimeric immunity protein Cmi solved by direct methods (Arcimboldo) | | Descriptor: | COLICIN-M IMMUNITY PROTEIN, PHOSPHATE ION | | Authors: | Zeth, K, Patzer, S.I, Albrecht, R, Uson, I, Braun, V. | | Deposit date: | 2012-01-12 | | Release date: | 2012-01-25 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (1.892 Å) | | Cite: | The Crystal Structure of the Dimeric Colicin M Immunity
J.Struct.Biol., 178, 2012
|
|
1E6F
 | | Human MIR-receptor, repeat 11 | | Descriptor: | CATION-INDEPENDENT MANNOSE-6-PHOSPHATE RECEPTOR | | Authors: | Von Buelow, R, Rajashankar, K.R, Dauter, M, Dauter, Z, Grimme, S, Schmidt, B, Von Figura, K, Uson, I. | | Deposit date: | 2000-08-15 | | Release date: | 2001-08-09 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Locating the Anomalous Scatterer Substructures in Halide and Sulfur Phasing
Acta Crystallogr.,Sect.D, 59, 2003
|
|
1GQB
 | | HUMAN MIR-RECEPTOR, REPEAT 11 | | Descriptor: | BROMIDE ION, CATION-INDEPENDENT MANNOSE-6-PHOSPHATE RECEPTOR | | Authors: | Von Buelow, R, Dauter, M, Dauter, Z, Rajashankar, K.R, Grimme, S, Schmidt, B, Von Figura, K, Uson, I. | | Deposit date: | 2001-11-22 | | Release date: | 2002-12-05 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Locating the Anomalous Scatterer Substructures in Halide and Sulfur Phasing
Acta Crystallogr.,Sect.D, 59, 2003
|
|
7ROX
 | | BthTX-I complexed with inhibitor MMV | | Descriptor: | 12-methoxy-Nb-methylvoachalotine, Basic phospholipase A2 homolog bothropstoxin-I | | Authors: | Borges, R.J, De Marino, I, Uson, I, Fontes, M.R.M. | | Deposit date: | 2021-08-02 | | Release date: | 2022-11-09 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structural and functional studies of a snake venom phospholipase A 2 -like protein complexed to an inhibitor from Tabernaemontana catharinensis.
Biochimie, 206, 2023
|
|
5M2X
 | | Crystal structure of the full-length Zika virus NS5 protein (Human isolate Z1106033) | | Descriptor: | NS5, PHOSPHATE ION, S-ADENOSYL-L-HOMOCYSTEINE, ... | | Authors: | Ferrero, D.S, Ruiz-Arroyo, V.M, Soler, N, Uson, I, Verdaguer, N. | | Deposit date: | 2016-10-13 | | Release date: | 2018-06-06 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (4.991 Å) | | Cite: | Supramolecular arrangement of the full-length Zika virus NS5.
Plos Pathog., 15, 2019
|
|
2WK1
 | | Structure of the O-methyltransferase NovP | | Descriptor: | 1,2-ETHANEDIOL, NOVP, S-ADENOSYL-L-HOMOCYSTEINE, ... | | Authors: | Gomez Garcia, I, Stevenson, C.E.M, Uson, I, Freel Meyers, C.L, Walsh, C.T, Lawson, D.M. | | Deposit date: | 2009-06-03 | | Release date: | 2009-12-15 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | The Crystal Structure of the Novobiocin Biosynthetic Enzyme Novp: The First Representative Structure for the Tylf O-Methyltransferase Superfamily.
J.Mol.Biol., 395, 2010
|
|
5EZU
 | | Crystal structure of the N-terminal domain of vaccinia virus immunomodulator A46 in complex with myristic acid. | | Descriptor: | MYRISTIC ACID, Protein A46 | | Authors: | Fedosyuk, S, Bezerra, G.A, Sammito, M, Uson, I, Skern, T. | | Deposit date: | 2015-11-26 | | Release date: | 2016-11-30 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | Vaccinia Virus Immunomodulator A46: A Lipid and Protein-Binding Scaffold for Sequestering Host TIR-Domain Proteins.
PLoS Pathog., 12, 2016
|
|
1E33
 | | Crystal structure of an Arylsulfatase A mutant P426L | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Arylsulfatase A, MAGNESIUM ION | | Authors: | von Buelow, R, Schmidt, B, Dierks, T, von Figura, K, Uson, I. | | Deposit date: | 2000-06-06 | | Release date: | 2001-05-25 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Defective oligomerization of arylsulfatase a as a cause of its instability in lysosomes and metachromatic leukodystrophy.
J. Biol. Chem., 277, 2002
|
|
6DD8
 | | Structure of mouse SYCP3, P21 form | | Descriptor: | Synaptonemal complex protein 3 | | Authors: | Rosenberg, S.C, Munoz, I.C, Uson, I, Corbett, K.D. | | Deposit date: | 2018-05-09 | | Release date: | 2018-08-01 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | A conserved filamentous assembly underlies the structure of the meiotic chromosome axis.
Elife, 8, 2019
|
|
6DD9
 | | Structure of mouse SYCP3, P1 form | | Descriptor: | Synaptonemal complex protein 3 | | Authors: | Rosenberg, S.C, Munoz, I.C, Uson, I, Corbett, K.D. | | Deposit date: | 2018-05-09 | | Release date: | 2018-08-01 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | A conserved filamentous assembly underlies the structure of the meiotic chromosome axis.
Elife, 8, 2019
|
|
3N6U
 | |
3N6S
 | | Crystal structure of human mitochondrial mTERF in complex with a 15-mer DNA encompassing the tRNALeu(UUR) binding sequence | | Descriptor: | DNA (5'-D(*AP*TP*GP*GP*CP*AP*GP*AP*GP*CP*CP*CP*GP*GP*T)-3'), DNA (5'-D(*TP*AP*CP*CP*GP*GP*GP*CP*TP*CP*TP*GP*CP*CP*A)-3'), Transcription termination factor, ... | | Authors: | Jimenez-Menendez, N, Fernandez-Millan, P, Rubio-Cosials, A, Arnan, C, Montoya, J, Jacobs, H.T, Bernado, P, Coll, M, Uson, I, Sola, M. | | Deposit date: | 2010-05-26 | | Release date: | 2010-06-16 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Human mitochondrial mTERF wraps around DNA through a left-handed superhelical tandem repeat.
Nat.Struct.Mol.Biol., 17, 2010
|
|
7B73
 | | Insight into the molecular determinants of thermal stability in halohydrin dehalogenase HheD2. | | Descriptor: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, GLYCEROL, Short-chain dehydrogenase/reductase SDR | | Authors: | Wessel, J, Petrillo, G, Estevez, M, Bosh, S, Seeger, M, Dijkman, W.P, Hidalgo, A, Uson, I, Osuna, S, Schallmey, A. | | Deposit date: | 2020-12-09 | | Release date: | 2021-04-07 | | Last modified: | 2024-06-19 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Insights into the molecular determinants of thermal stability in halohydrin dehalogenase HheD2.
Febs J., 288, 2021
|
|
7TA2
 | | Crystal structure of the human sperm-expressed surface protein SPACA6 | | Descriptor: | BROMIDE ION, Sperm acrosome membrane-associated protein 6 | | Authors: | Vance, T.D.R, Yip, P, Jimenez, E, Uson, I, Lee, J.E. | | Deposit date: | 2021-12-20 | | Release date: | 2022-08-31 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | SPACA6 ectodomain structure reveals a conserved superfamily of gamete fusion-associated proteins.
Commun Biol, 5, 2022
|
|
7KFL
 | | Crystal structure of the cargo-binding domain from the plant class XI myosin (MyoXIk) | | Descriptor: | Myosin-17 | | Authors: | Turowski, V.R, Ruiz, D.M, Nascimento, A.F.Z, Millan, C, Sammito, M.D, Juanhuix, J, Cremonesi, A.S, Uson, I, Giuseppe, P.O, Murakami, M.T. | | Deposit date: | 2020-10-14 | | Release date: | 2021-04-21 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Structure of the class XI myosin globular tail reveals evolutionary hallmarks for cargo recognition in plants.
Acta Crystallogr D Struct Biol, 77, 2021
|
|
2Y8P
 | | Crystal Structure of an Outer Membrane-Anchored Endolytic Peptidoglycan Lytic Transglycosylase (MltE) from Escherichia coli | | Descriptor: | ENDO-TYPE MEMBRANE-BOUND LYTIC MUREIN TRANSGLYCOSYLASE A | | Authors: | Artola-Recolons, C, Carrasco-Lopez, C, Llarrull, L.I, Kumarasiri, M, Lastochkin, E, Martinez-Ilarduya, I, Meindl, K, Uson, I, Mobashery, S, Hermoso, J.A. | | Deposit date: | 2011-02-08 | | Release date: | 2011-04-13 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.995 Å) | | Cite: | High-Resolution Crystal Structure of Mlte, an Outer Membrane-Anchored Endolytic Peptidoglycan Lytic Transglycosylase from Escherichia Coli.
Biochemistry, 50, 2011
|
|
3L0O
 | | Structure of RNA-free Rho transcription termination factor from Thermotoga maritima | | Descriptor: | SODIUM ION, SULFATE ION, Transcription termination factor rho, ... | | Authors: | Canals, A, Uson, I, Coll, M. | | Deposit date: | 2009-12-10 | | Release date: | 2010-05-26 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | The Structure of RNA-Free Rho Termination Factor Indicates a Dynamic Mechanism of Transcript Capture
J.Mol.Biol., 400, 2010
|
|
4YT9
 | | Crystal structure of Porphyromonas gingivalis peptidylarginine deiminase (PPAD) substrate-unbound. | | Descriptor: | GLYCEROL, Peptidylarginine deiminase, SODIUM ION | | Authors: | Goulas, T, Mizgalska, D, Garcia-Ferrer, I, Kantyka, T, Guevara, T, Szmigielski, B, Sroka, A, Millan, C, Uson, I, Veillard, F, Potempa, B, Mydel, P, Sola, M, Potempa, J, Gomis-Ruth, F.X. | | Deposit date: | 2015-03-17 | | Release date: | 2015-07-15 | | Last modified: | 2025-04-09 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Structure and mechanism of a bacterial host-protein citrullinating virulence factor, Porphyromonas gingivalis peptidylarginine deiminase.
Sci Rep, 5, 2015
|
|
4YTB
 | | Crystal structure of Porphyromonas gingivalis peptidylarginine deiminase (PPAD) in complex with dipeptide Asp-Gln. | | Descriptor: | ASPARTIC ACID, AZIDE ION, CHLORIDE ION, ... | | Authors: | Goulas, T, Mizgalska, D, Garcia-Ferrer, I, Kantyka, T, Guevara, T, Szmigielski, B, Sroka, A, Millan, C, Uson, I, Veillard, F, Potempa, B, Mydel, P, Sola, M, Potempa, J, Gomis-Ruth, F.X. | | Deposit date: | 2015-03-17 | | Release date: | 2015-07-01 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Structure and mechanism of a bacterial host-protein citrullinating virulence factor, Porphyromonas gingivalis peptidylarginine deiminase.
Sci Rep, 5, 2015
|
|
4YTG
 | | Crystal structure of Porphyromonas gingivalis peptidylarginine deiminase (PPAD) mutant C351A in complex with dipeptide Met-Arg. | | Descriptor: | ARGININE, AZIDE ION, CHLORIDE ION, ... | | Authors: | Goulas, T, Mizgalska, D, Garcia-Ferrer, I, Kantyka, T, Guevara, T, Szmigielski, B, Sroka, A, Millan, C, Uson, I, Veillard, F, Potempa, B, Mydel, P, Sola, M, Potempa, J, Gomis-Ruth, F.X. | | Deposit date: | 2015-03-17 | | Release date: | 2015-07-01 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structure and mechanism of a bacterial host-protein citrullinating virulence factor, Porphyromonas gingivalis peptidylarginine deiminase.
Sci Rep, 5, 2015
|
|
