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1IKO
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BU of 1iko by Molmil
CRYSTAL STRUCTURE OF THE MURINE EPHRIN-B2 ECTODOMAIN
Descriptor: EPHRIN-B2, alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Toth, J, Cutforth, T, Gelinas, A.D, Bethoney, K.A, Bard, J, Harrison, C.J.
Deposit date:2001-05-03
Release date:2002-05-03
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Crystal structure of an ephrin ectodomain.
Dev.Cell, 1, 2001
4GCY
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BU of 4gcy by Molmil
Structure of Mycobacterium tuberculosis dUTPase H21W mutant
Descriptor: 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Deoxyuridine 5'-triphosphate nucleotidohydrolase, ...
Authors:Toth, J, Vertessy, B.G, Leveles, I, Bendes, A.
Deposit date:2012-07-31
Release date:2013-07-03
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:RAMD identification of substrate binding pathways to the active site of dUTPase
To be Published
2O1P
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BU of 2o1p by Molmil
Structure of yeast Poly(A) Polymerase in a somewhat closed state
Descriptor: Poly(A) polymerase
Authors:Bohm, A, Balbo, P, Toth, J.
Deposit date:2006-11-29
Release date:2007-01-23
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:X-ray crystallographic and steady state fluorescence characterization of the protein dynamics of yeast polyadenylate polymerase.
J.Mol.Biol., 366, 2007
3IF7
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BU of 3if7 by Molmil
Structure of Calmodulin complexed with its first endogenous inhibitor, sphingosylphosphorylcholine
Descriptor: 2-{[(R)-{[(2S,3R,4E)-2-amino-3-hydroxyoctadec-4-en-1-yl]oxy}(hydroxy)phosphoryl]oxy}-N,N,N-trimethylethanaminium, CALCIUM ION, Calmodulin
Authors:Kovacs, E, Harmat, V, Toth, J, Vertessy, B.G, Modos, K, Kardos, J, Liliom, K.
Deposit date:2009-07-24
Release date:2010-06-30
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure and mechanism of calmodulin binding to a signaling sphingolipid reveal new aspects of lipid-protein interactions
Faseb J., 24, 2010
5EDD
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BU of 5edd by Molmil
Crystal structure of Mycobacterium tuberculosis dUTPase R140K, H145W mutant
Descriptor: 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Deoxyuridine 5'-triphosphate nucleotidohydrolase, ...
Authors:Nagy, G.N, Leveles, I, Lopata, A, Harmat, V, Toth, J, Vertessy, G.B.
Deposit date:2015-10-21
Release date:2016-11-02
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Structural Characterization of Arginine Fingers: Identification of an Arginine Finger for the Pyrophosphatase dUTPases.
J. Am. Chem. Soc., 138, 2016
2HHP
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BU of 2hhp by Molmil
Structure of yeast poly(A) polymerase in a closed conformation.
Descriptor: CITRATE ANION, MAGNESIUM ION, Poly(A) polymerase
Authors:Bohm, A, Toth, J.
Deposit date:2006-06-28
Release date:2007-01-23
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:X-ray crystallographic and steady state fluorescence characterization of the protein dynamics of yeast polyadenylate polymerase.
J.Mol.Biol., 366, 2007
3H6D
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BU of 3h6d by Molmil
Structure of the mycobacterium tuberculosis DUTPase D28N mutant
Descriptor: 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Deoxyuridine 5'-triphosphate nucleotidohydrolase, ...
Authors:Leveles, I, Harmat, V, Nagy, G, Takacs, E, Lopata, A, Toth, J, Vertessy, B.G.
Deposit date:2009-04-23
Release date:2009-11-24
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Direct contacts between conserved motifs of different subunits provide major contribution to active site organization in human and mycobacterial dUTPases.
Febs Lett., 584, 2010
3HZA
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BU of 3hza by Molmil
Crystal structure of dUTPase H145W mutant
Descriptor: 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Deoxyuridine 5'-triphosphate nucleotidohydrolase, ...
Authors:Leveles, I, Harmat, V, Pecsi, I, Toth, J, Vertessy, B.G.
Deposit date:2009-06-23
Release date:2009-11-24
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Aromatic stacking between nucleobase and enzyme promotes phosphate ester hydrolysis in dUTPase.
Nucleic Acids Res., 38, 2010
4GV8
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BU of 4gv8 by Molmil
DUTPase from phage phi11 of S.aureus: visualization of the species-specific insert
Descriptor: 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, DUTPase, MAGNESIUM ION
Authors:Leveles, I, Harmat, V, Nemeth, V, Bendes, A, Szabo, J, Kadar, V, Zagyva, I, Rona, G, Toth, J, Vertessy, B.G.
Deposit date:2012-08-30
Release date:2013-09-11
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure and enzymatic mechanism of a moonlighting dUTPase
Acta Crystallogr.,Sect.D, 69, 2013
3I93
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BU of 3i93 by Molmil
Crystal structure of Mycobacterium tuberculosis dUTPase STOP138T mutant
Descriptor: 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Deoxyuridine 5'-triphosphate nucleotidohydrolase, ...
Authors:Leveles, I, Harmat, V, Lopata, A, Toth, J, Vertessy, B.G.
Deposit date:2009-07-10
Release date:2009-11-24
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Direct contacts between conserved motifs of different subunits provide major contribution to active site organization in human and mycobacterial dUTPases.
Febs Lett., 584, 2010
3LOJ
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BU of 3loj by Molmil
Structure of Mycobacterium tuberculosis dUTPase H145A mutant
Descriptor: 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Deoxyuridine 5'-triphosphate nucleotidohydrolase, ...
Authors:Leveles, I, Harmat, V, Pecsi, I, Lopata, A, Vertessy, B.G, Toth, J.
Deposit date:2010-02-04
Release date:2010-08-11
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Aromatic stacking between nucleobase and enzyme promotes phosphate ester hydrolysis in dUTPase
Nucleic Acids Res., 38, 2010
2HQU
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BU of 2hqu by Molmil
Human dUTPase in complex with alpha,beta-iminodUTP and magnesium ion
Descriptor: 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, CHLORIDE ION, Deoxyuridine 5'-triphosphate nucleotidohydrolase, ...
Authors:Barabas, O, Varga, B, Vertessy, B.G.
Deposit date:2006-07-19
Release date:2007-07-24
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Active site closure facilitates juxtaposition of reactant atoms for initiation of catalysis by human dUTPase.
Febs Lett., 581, 2007
5ECT
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BU of 5ect by Molmil
Mycobacterium tuberculosis dUTPase G143STOP mutant
Descriptor: 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Deoxyuridine 5'-triphosphate nucleotidohydrolase, ...
Authors:Nagy, G.N, Leveles, I, Harmat, V, Vertessy, G.B.
Deposit date:2015-10-20
Release date:2016-11-02
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Structural Characterization of Arginine Fingers: Identification of an Arginine Finger for the Pyrophosphatase dUTPases.
J. Am. Chem. Soc., 138, 2016
3EHW
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BU of 3ehw by Molmil
Human dUTPase in complex with alpha,beta-imido-dUTP and Mg2+: visualization of the full-length C-termini in all monomers and suggestion for an additional metal ion binding site
Descriptor: 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, MAGNESIUM ION, dUTP pyrophosphatase
Authors:Takacs, E, Barabas, O, Vertessy, B.G.
Deposit date:2008-09-15
Release date:2008-09-30
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Human dUTPase in complex with alpha,beta-imido-dUTP and Mg2+: visualization of the full-length C-termini in all monomers and suggestion for an additional metal ion binding site
To be Published
4MZ5
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BU of 4mz5 by Molmil
Structure of importin-alpha: dUTPase NLS complex
Descriptor: Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial, Importin subunit alpha-1
Authors:Marfori, M, Rona, G, Vertessy, B.G, Kobe, B.
Deposit date:2013-09-29
Release date:2013-11-13
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Phosphorylation adjacent to the nuclear localization signal of human dUTPase abolishes nuclear import: structural and mechanistic insights.
Acta Crystallogr.,Sect.D, 69, 2013
4MZ6
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BU of 4mz6 by Molmil
Structure of importin-alpha: dUTPase S11E NLS mutant complex
Descriptor: Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial, Importin subunit alpha-1
Authors:Marfori, M, Rona, G, Vertessy, B.G, Kobe, B.
Deposit date:2013-09-29
Release date:2013-11-13
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Phosphorylation adjacent to the nuclear localization signal of human dUTPase abolishes nuclear import: structural and mechanistic insights.
Acta Crystallogr.,Sect.D, 69, 2013

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