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5LZU
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BU of 5lzu by Molmil
Structure of the mammalian ribosomal termination complex with accommodated eRF1
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ...
Authors:Shao, S, Murray, J, Brown, A, Taunton, J, Ramakrishnan, V, Hegde, R.S.
Deposit date:2016-10-02
Release date:2016-11-30
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (3.75 Å)
Cite:Decoding Mammalian Ribosome-mRNA States by Translational GTPase Complexes.
Cell, 167, 2016
5LZT
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BU of 5lzt by Molmil
Structure of the mammalian ribosomal termination complex with eRF1 and eRF3.
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 5.8S ribosomal RNA, ...
Authors:Shao, S, Murray, J, Brown, A, Taunton, J, Ramakrishnan, V, Hegde, R.S.
Deposit date:2016-10-02
Release date:2016-11-30
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (3.65 Å)
Cite:Decoding Mammalian Ribosome-mRNA States by Translational GTPase Complexes.
Cell, 167, 2016
5LZS
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BU of 5lzs by Molmil
Structure of the mammalian ribosomal elongation complex with aminoacyl-tRNA, eEF1A, and didemnin B
Descriptor: (2~{S})-~{N}-[(2~{R})-1-[[(3~{S},6~{S},8~{S},12~{S},13~{R},16~{S},17~{R},20~{S},23~{S})-13-[(2~{S})-butan-2-yl]-20-[(4-methoxyphenyl)methyl]-6,17,21-trimethyl-3-(2-methylpropyl)-12-oxidanyl-2,5,7,10,15,19,22-heptakis(oxidanylidene)-8-propan-2-yl-9,18-dioxa-1,4,14,21-tetrazabicyclo[21.3.0]hexacosan-16-yl]amino]-4-methyl-1-oxidanylidene-pentan-2-yl]-~{N}-methyl-1-[(2~{S})-2-oxidanylpropanoyl]pyrrolidine-2-carboxamide, 18S ribosomal RNA, 28S ribosomal RNA, ...
Authors:Shao, S, Murray, J, Brown, A, Taunton, J, Ramakrishnan, V, Hegde, R.S.
Deposit date:2016-10-02
Release date:2016-11-30
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (3.31 Å)
Cite:Decoding Mammalian Ribosome-mRNA States by Translational GTPase Complexes.
Cell, 167, 2016
5LZY
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BU of 5lzy by Molmil
Structure of the mammalian rescue complex with Pelota and Hbs1l assembled on a polyadenylated mRNA.
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ...
Authors:Shao, S, Murray, J, Brown, A, Taunton, J, Ramakrishnan, V, Hegde, R.S.
Deposit date:2016-10-02
Release date:2016-11-30
Last modified:2019-10-23
Method:ELECTRON MICROSCOPY (3.99 Å)
Cite:Decoding Mammalian Ribosome-mRNA States by Translational GTPase Complexes.
Cell, 167, 2016
5LZZ
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BU of 5lzz by Molmil
Structure of the mammalian rescue complex with Pelota and Hbs1l (combined)
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ...
Authors:Shao, S, Murray, J, Brown, A, Taunton, J, Ramakrishnan, V, Hegde, R.S.
Deposit date:2016-10-02
Release date:2016-11-30
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (3.47 Å)
Cite:Decoding Mammalian Ribosome-mRNA States by Translational GTPase Complexes.
Cell, 167, 2016
5LZV
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BU of 5lzv by Molmil
Structure of the mammalian ribosomal termination complex with accommodated eRF1(AAQ) and ABCE1.
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 5.8S ribosomal RNA, ...
Authors:Shao, S, Murray, J, Brown, A, Taunton, J, Ramakrishnan, V, Hegde, R.S.
Deposit date:2016-10-02
Release date:2016-11-30
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (3.35 Å)
Cite:Decoding Mammalian Ribosome-mRNA States by Translational GTPase Complexes.
Cell, 167, 2016
5LZX
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BU of 5lzx by Molmil
Structure of the mammalian rescue complex with Pelota and Hbs1l assembled on a UGA stop codon.
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ...
Authors:Shao, S, Murray, J, Brown, A, Taunton, J, Ramakrishnan, V, Hegde, R.S.
Deposit date:2016-10-02
Release date:2016-11-30
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (3.67 Å)
Cite:Decoding Mammalian Ribosome-mRNA States by Translational GTPase Complexes.
Cell, 167, 2016
5LZW
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BU of 5lzw by Molmil
Structure of the mammalian rescue complex with Pelota and Hbs1l assembled on a truncated mRNA.
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 5.8S ribosomal RNA, ...
Authors:Shao, S, Murray, J, Brown, A, Taunton, J, Ramakrishnan, V, Hegde, R.S.
Deposit date:2016-10-02
Release date:2016-11-30
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (3.53 Å)
Cite:Decoding Mammalian Ribosome-mRNA States by Translational GTPase Complexes.
Cell, 167, 2016
3J92
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BU of 3j92 by Molmil
Structure and assembly pathway of the ribosome quality control complex
Descriptor: 28S rRNA, 5.8S rRNA, 5S rRNA, ...
Authors:Shao, S, Brown, A, Santhanam, B, Hegde, R.S.
Deposit date:2014-12-02
Release date:2015-01-21
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structure and Assembly Pathway of the Ribosome Quality Control Complex.
Mol.Cell, 57, 2015
6SGC
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BU of 6sgc by Molmil
Rabbit 80S ribosome stalled on a poly(A) tail
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ...
Authors:Chandrasekaran, V, Juszkiewicz, S, Choi, J, Puglisi, J.D, Brown, A, Shao, S, Ramakrishnan, V, Hegde, R.S.
Deposit date:2019-08-03
Release date:2019-12-04
Last modified:2022-03-30
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Mechanism of ribosome stalling during translation of a poly(A) tail.
Nat.Struct.Mol.Biol., 26, 2019
7MDZ
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BU of 7mdz by Molmil
80S rabbit ribosome stalled with benzamide-CHX
Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S21, ...
Authors:Koga, Y, Hoang, E.M, Park, Y, Keszei, A.F.A, Murray, J, Shao, S, Liau, B.B.
Deposit date:2021-04-06
Release date:2021-09-01
Last modified:2021-09-15
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Discovery of C13-Aminobenzoyl Cycloheximide Derivatives that Potently Inhibit Translation Elongation.
J.Am.Chem.Soc., 143, 2021
8SCB
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BU of 8scb by Molmil
Terminating ribosome with SRI-41315
Descriptor: (2S,4aS)-2-cyclobutyl-10-methyl-3-phenyl-2,10-dihydropyrimido[4,5-b]quinoline-4,5(3H,4aH)-dione, 18S_rRNA, 28S_rRNA, ...
Authors:Yip, M.C.J, Coelho, J.P.L, Oltion, K, Tauton, J, Shao, S.
Deposit date:2023-04-05
Release date:2023-12-27
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Structure and consequences of eRF1 glued to the ribosomal decoding center
To Be Published
7RUC
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BU of 7ruc by Molmil
Metazoan pre-targeting GET complex with SGTA (cBUGGS)
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, ATPase GET3, Golgi to ER traffic protein 4 homolog, ...
Authors:Keszei, A.F.A, Yip, M.C.J, Shao, S.
Deposit date:2021-08-16
Release date:2021-12-15
Last modified:2021-12-22
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structural insights into metazoan pretargeting GET complexes.
Nat.Struct.Mol.Biol., 28, 2021
7RUA
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BU of 7rua by Molmil
Metazoan pre-targeting GET complex (cBUGG-out)
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, ATPase GET3, Golgi to ER traffic protein 4 homolog, ...
Authors:Keszei, A.F.A, Yip, M.C.J, Shao, S.
Deposit date:2021-08-16
Release date:2021-12-15
Last modified:2021-12-22
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural insights into metazoan pretargeting GET complexes.
Nat.Struct.Mol.Biol., 28, 2021
7RU9
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BU of 7ru9 by Molmil
Metazoan pre-targeting GET complex (cBUGG-in)
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, ATPase GET3, Golgi to ER traffic protein 4 homolog, ...
Authors:Keszei, A.F.A, Yip, M.C.J, Shao, S.
Deposit date:2021-08-16
Release date:2021-12-15
Last modified:2021-12-22
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural insights into metazoan pretargeting GET complexes.
Nat.Struct.Mol.Biol., 28, 2021
6T59
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BU of 6t59 by Molmil
Structure of rabbit 80S ribosome translating beta-tubulin in complex with tetratricopeptide protein 5 and nascent chain-associated complex
Descriptor: 28S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ...
Authors:Lin, Z, Gasic, I, Chandrasekaran, V, Peters, N, Shao, S, Ramakrishnan, V, Mitchison, T.J, Hegde, R.S.
Deposit date:2019-10-15
Release date:2019-11-27
Last modified:2020-01-15
Method:ELECTRON MICROSCOPY (3.11 Å)
Cite:TTC5 mediates autoregulation of tubulin via mRNA degradation.
Science, 367, 2020
6VM6
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BU of 6vm6 by Molmil
Structure of Acinetobacter baumannii Cap4 SAVED/CARF-domain containing receptor with the cyclic trinucleotide 2'3'3'-cAAA
Descriptor: 2'-5'-Linked Cyclic RNA (5'-R(P*AP*AP*A)-3'), SAVED domain-containing protein, SULFATE ION
Authors:Lowey, B, Whiteley, A.T, Keszei, A.F.A, Morehouse, B.R, Antine, S.P, Cabrera, V, Schwede, F, Mekalanos, J.J, Shao, S, Lee, A.S.Y, Kranzusch, P.J.
Deposit date:2020-01-27
Release date:2020-06-17
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:CBASS Immunity Uses CARF-Related Effectors to Sense 3'-5'- and 2'-5'-Linked Cyclic Oligonucleotide Signals and Protect Bacteria from Phage Infection.
Cell, 182, 2020
6VM5
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BU of 6vm5 by Molmil
Structure of Moraxella osloensis Cap4 SAVED/CARF-domain containing receptor
Descriptor: MAGNESIUM ION, SAVED domain-containing protein
Authors:Lowey, B, Whiteley, A.T, Keszei, A.F.A, Morehouse, B.R, Antine, S.P, Cabrera, V, Schwede, F, Mekalanos, J.J, Shao, S, Lee, A.S.Y, Kranzusch, P.J.
Deposit date:2020-01-27
Release date:2020-06-17
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:CBASS Immunity Uses CARF-Related Effectors to Sense 3'-5'- and 2'-5'-Linked Cyclic Oligonucleotide Signals and Protect Bacteria from Phage Infection.
Cell, 182, 2020
6WAN
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BU of 6wan by Molmil
Structure of Acinetobacter baumannii Cap4 SAVED/CARF-domain containing receptor with the cyclic trinucleotide 3'3'3'-cAAA
Descriptor: Cyclic RNA (R(P*AP*AP*A), SAVED domain-containing protein, SULFATE ION
Authors:Lowey, B, Whiteley, A.T, Keszei, A.F.A, Morehouse, B.R, Antine, S.P, Cabrera, V, Schwede, F, Mekalanos, J.J, Shao, S, Lee, A.S.Y, Kranzusch, P.J.
Deposit date:2020-03-25
Release date:2020-06-17
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:CBASS Immunity Uses CARF-Related Effectors to Sense 3'-5'- and 2'-5'-Linked Cyclic Oligonucleotide Signals and Protect Bacteria from Phage Infection.
Cell, 182, 2020
6WAM
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BU of 6wam by Molmil
Structure of Acinetobacter baumannii Cap4 SAVED/CARF-domain containing receptor
Descriptor: SAVED domain-containing protein, SULFATE ION
Authors:Lowey, B, Whiteley, A.T, Keszei, A.F.A, Morehouse, B.R, Antine, S.P, Cabrera, V, Schwede, F, Mekalanos, J.J, Shao, S, Lee, A.S.Y, Kranzusch, P.J.
Deposit date:2020-03-25
Release date:2020-06-17
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:CBASS Immunity Uses CARF-Related Effectors to Sense 3'-5'- and 2'-5'-Linked Cyclic Oligonucleotide Signals and Protect Bacteria from Phage Infection.
Cell, 182, 2020
6WT9
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BU of 6wt9 by Molmil
Structure of STING-associated CdnE c-di-GMP synthase from Capnocytophaga granulosa
Descriptor: NTP_transf_2 domain-containing protein
Authors:Morehouse, B.R, Govande, A.A, Millman, A, Keszei, A.F.A, Lowey, B, Ofir, G, Shao, S, Sorek, R, Kranzusch, P.J.
Deposit date:2020-05-01
Release date:2020-09-09
Last modified:2020-10-28
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:STING cyclic dinucleotide sensing originated in bacteria.
Nature, 586, 2020
6WT6
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BU of 6wt6 by Molmil
Structure of a metazoan TIR-STING receptor from C. gigas
Descriptor: Metazoan TIR-STING fusion
Authors:Morehouse, B.R, Govande, A.A, Millman, A, Keszei, A.F.A, Lowey, B, Ofir, G, Shao, S, Sorek, R, Kranzusch, P.J.
Deposit date:2020-05-01
Release date:2020-09-09
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:STING cyclic dinucleotide sensing originated in bacteria.
Nature, 586, 2020
6WT5
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BU of 6wt5 by Molmil
Structure of a bacterial STING receptor from Capnocytophaga granulosa
Descriptor: Bacterial STING
Authors:Morehouse, B.R, Govande, A.A, Millman, A, Keszei, A.F.A, Lowey, B, Ofir, G, Shao, S, Sorek, R, Kranzusch, P.J.
Deposit date:2020-05-01
Release date:2020-09-09
Last modified:2020-10-28
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:STING cyclic dinucleotide sensing originated in bacteria.
Nature, 586, 2020
6WT8
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BU of 6wt8 by Molmil
Structure of a STING-associated CdnE c-di-GMP synthase from Flavobacteriaceae sp.
Descriptor: STING-associated CdnE c-di-GMP synthase
Authors:Morehouse, B.R, Govande, A.A, Millman, A, Keszei, A.F.A, Lowey, B, Ofir, G, Shao, S, Sorek, R, Kranzusch, P.J.
Deposit date:2020-05-01
Release date:2020-09-09
Last modified:2020-10-28
Method:X-RAY DIFFRACTION (1.52 Å)
Cite:STING cyclic dinucleotide sensing originated in bacteria.
Nature, 586, 2020
6WT4
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BU of 6wt4 by Molmil
Structure of a bacterial STING receptor from Flavobacteriaceae sp. in complex with 3',3'-cGAMP
Descriptor: 2-amino-9-[(2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-9-(6-amino-9H-purin-9-yl)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecin-2-yl]-1,9-dihydro-6H-purin-6-one, Bacterial STING, SULFATE ION
Authors:Morehouse, B.R, Govande, A.A, Millman, A, Keszei, A.F.A, Lowey, B, Ofir, G, Shao, S, Sorek, R, Kranzusch, P.J.
Deposit date:2020-05-01
Release date:2020-09-09
Last modified:2020-10-28
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:STING cyclic dinucleotide sensing originated in bacteria.
Nature, 586, 2020

 

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