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8GH4
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BU of 8gh4 by Molmil
Complex of Adam 10 disentegrin cysteine rich domains with human monoclonal antibody
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody heavy chain, Antibody light chain, ...
Authors:Nikolov, D.B, Saha, N, Xu, K, Goldgur, Y.
Deposit date:2023-03-09
Release date:2023-08-30
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Fully human monoclonal antibody targeting activated ADAM10 on colorectal cancer cells.
Biomed Pharmacother, 161, 2023
5L0Q
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BU of 5l0q by Molmil
Crystal structure of the complex between ADAM10 D+C domain and a conformation specific mAb 8C7.
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Disintegrin and metalloproteinase domain-containing protein 10, MAGNESIUM ION, ...
Authors:Xu, K, Saha, N, Nikolov, D.B.
Deposit date:2016-07-28
Release date:2016-11-09
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.759 Å)
Cite:An activated form of ADAM10 is tumor selective and regulates cancer stem-like cells and tumor growth.
J.Exp.Med., 213, 2016
4P91
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BU of 4p91 by Molmil
Crystal structure of the nogo-receptor-2 (27-330)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Reticulon-4 receptor-like 2
Authors:Semavina, M, Saha, N, Kolev, M, Goldgur, Y, Giger, R, Himanen, J, Nikolov, D.
Deposit date:2014-04-01
Release date:2014-04-30
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of the Nogo-receptor-2.
Protein Sci., 20, 2011
4P8S
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BU of 4p8s by Molmil
Crystal structure of Nogo-receptor-2
Descriptor: 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Semavina, M, Saha, N, Kolev, M.V, Giger, R.J, Himanen, J.P, Nikolov, D.B.
Deposit date:2014-04-01
Release date:2014-04-09
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of the Nogo-receptor-2.
Protein Sci., 2011
2AO7
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BU of 2ao7 by Molmil
Adam10 Disintegrin and cysteine- rich domain
Descriptor: ADAM 10, SULFATE ION
Authors:Janes, P.W, Saha, N, Barton, W.A, Kolev, M.V, Wimmer-Kleikamp, S.H, Nievergall, E, Blobel, C.P, Himanen, J.-P, Lackmann, M, Nikolov, D.B.
Deposit date:2005-08-12
Release date:2006-08-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Adam meets Eph: an ADAM substrate recognition module acts as a molecular switch for ephrin cleavage in trans.
Cell(Cambridge,Mass.), 123, 2005
6BDZ
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BU of 6bdz by Molmil
ADAM10 Extracellular Domain Bound by the 11G2 Fab
Descriptor: 11G2 Fab Heavy Chain, 11G2 Fab Light Chain, CALCIUM ION, ...
Authors:Seegar, T.C.M.
Deposit date:2017-10-24
Release date:2017-12-27
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural Basis for Regulated Proteolysis by the alpha-Secretase ADAM10.
Cell, 171, 2017
6BE6
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BU of 6be6 by Molmil
ADAM10 Extracellular Domain
Descriptor: CALCIUM ION, Disintegrin and metalloproteinase domain-containing protein 10, SULFATE ION, ...
Authors:Seegar, T.C.M.
Deposit date:2017-10-24
Release date:2017-12-27
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Basis for Regulated Proteolysis by the alpha-Secretase ADAM10.
Cell, 171, 2017
7S7K
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BU of 7s7k by Molmil
Crystal structure of the EphB2 extracellular domain
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ephrin type-B receptor 2, ...
Authors:Xu, Y, Xu, K, Nikolov, D.B.
Deposit date:2021-09-16
Release date:2021-10-27
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:The Ephb2 Receptor Uses Homotypic, Head-to-Tail Interactions within Its Ectodomain as an Autoinhibitory Control Mechanism.
Int J Mol Sci, 22, 2021

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