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1DCQ
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BU of 1dcq by Molmil
CRYSTAL STRUCTURE OF THE ARF-GAP DOMAIN AND ANKYRIN REPEATS OF PAPBETA.
Descriptor: PYK2-ASSOCIATED PROTEIN BETA, ZINC ION
Authors:Mandiyan, V, Andreev, J, Schlessinger, J, Hubbard, S.R.
Deposit date:1999-11-05
Release date:1999-12-22
Last modified:2016-12-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of the ARF-GAP domain and ankyrin repeats of PYK2-associated protein beta.
EMBO J., 18, 1999
3JS2
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BU of 3js2 by Molmil
Crystal structure of minimal kinase domain of fibroblast growth factor receptor 1 in complex with 5-(2-thienyl)nicotinic acid
Descriptor: 5-(2-thienyl)nicotinic acid, Basic fibroblast growth factor receptor 1, PHOSPHATE ION
Authors:Bae, J.H, Ravindranathan, K.P, Mandiyan, V, Ekkati, A.R, Schlessinger, J, Jorgensen, W.L.
Deposit date:2009-09-09
Release date:2010-02-23
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Discovery of novel fibroblast growth factor receptor 1 kinase inhibitors by structure-based virtual screening
J.Med.Chem., 53, 2010
3KXX
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BU of 3kxx by Molmil
Structure of the mutant Fibroblast Growth Factor receptor 1
Descriptor: Basic fibroblast growth factor receptor 1
Authors:Bae, J.H, Boggon, T.J, Tome, F, Mandiyan, V, Lax, I, Schlessinger, J.
Deposit date:2009-12-04
Release date:2010-03-02
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Asymmetric receptor contact is required for tyrosine autophosphorylation of fibroblast growth factor receptor in living cells.
Proc.Natl.Acad.Sci.USA, 107, 2010
3KY2
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BU of 3ky2 by Molmil
Crystal structure of Fibroblast Growth Factor Receptor 1 kinase domain
Descriptor: Basic fibroblast growth factor receptor 1, SULFATE ION
Authors:Bae, J.H, Boggon, T.J, Tome, F, Mandiyan, V, Lax, I, Schlessinger, J.
Deposit date:2009-12-04
Release date:2010-03-02
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Asymmetric receptor contact is required for tyrosine autophosphorylation of fibroblast growth factor receptor in living cells.
Proc.Natl.Acad.Sci.USA, 107, 2010
1YXT
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BU of 1yxt by Molmil
Crystal Structure of Kinase Pim1 in complex with AMPPNP
Descriptor: PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Proto-oncogene serine/threonine-protein kinase Pim-1
Authors:Kumar, A, Mandiyan, V, Suzuki, Y, Zhang, C, Rice, J, Tsai, J, Artis, D.R, Ibrahim, P, Bremer, R.
Deposit date:2005-02-22
Release date:2005-04-26
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structures of proto-oncogene kinase Pim1: a target of aberrant somatic hypermutations in diffuse large cell lymphoma.
J.Mol.Biol., 348, 2005
1YXX
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Crystal Structure of Kinase Pim1 in complex with (3E)-3-[(4-HYDROXYPHENYL)IMINO]-1H-INDOL-2(3H)-ONE
Descriptor: (3E)-3-[(4-HYDROXYPHENYL)IMINO]-1H-INDOL-2(3H)-ONE, IMIDAZOLE, Proto-oncogene serine/threonine-protein kinase Pim-1
Authors:Kumar, A, Mandiyan, V, Suzuki, Y, Zhang, C, Rice, J, Tsai, J, Artis, D.R, Ibrahim, P, Bremer, R.
Deposit date:2005-02-22
Release date:2005-04-26
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structures of proto-oncogene kinase Pim1: a target of aberrant somatic hypermutations in diffuse large cell lymphoma.
J.Mol.Biol., 348, 2005
1YXU
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BU of 1yxu by Molmil
Crystal Structure of Kinase Pim1 in Complex with AMP
Descriptor: ADENOSINE MONOPHOSPHATE, IMIDAZOLE, Proto-oncogene serine/threonine-protein kinase Pim-1
Authors:Kumar, A, Mandiyan, V, Suzuki, Y, Zhang, C, Rice, J, Tsai, J, Artis, D.R, Ibrahim, P, Bremer, R.
Deposit date:2005-02-22
Release date:2005-04-26
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.24 Å)
Cite:Crystal Structures of Proto-oncogene Kinase Pim1: A Target of Aberrant Somatic Hypermutations in Diffuse Large Cell Lymphoma.
J.Mol.Biol., 348, 2005
1YWV
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BU of 1ywv by Molmil
Crystal Structures of Proto-Oncogene Kinase Pim1: a Target of Aberrant Somatic Hypermutations in Diffuse Large Cell Lymphoma
Descriptor: IMIDAZOLE, Proto-oncogene serine/threonine-protein kinase Pim-1
Authors:Kumar, A, Mandiyan, V, Suzuki, Y, Zhang, C, Rice, J, Tsai, J, Artis, D.R, Ibrahim, P, Bremer, R.
Deposit date:2005-02-18
Release date:2005-04-26
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structures of proto-oncogene kinase Pim1: a target of aberrant somatic hypermutations in diffuse large cell lymphoma.
J.Mol.Biol., 348, 2005
1YXV
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BU of 1yxv by Molmil
Crystal Structure of Kinase Pim1 in complex with 3,4-Dihydroxy-1-methylquinolin-2(1H)-one
Descriptor: 3,4-DIHYDROXY-1-METHYLQUINOLIN-2(1H)-ONE, IMIDAZOLE, Proto-oncogene serine/threonine-protein kinase Pim-1
Authors:Kumar, A, Mandiyan, V, Suzuki, Y, Zhang, C, Rice, J, Tsai, J, Artis, D.R, Ibrahim, P, Bremer, R.
Deposit date:2005-02-22
Release date:2005-04-26
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structures of Proto-oncogene Kinase Pim1: A Target of Aberrant Somatic Hypermutations in Diffuse Large Cell Lymphoma.
J.Mol.Biol., 348, 2005
1YXS
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BU of 1yxs by Molmil
Crystal Structure of Kinase Pim1 with P123M mutation
Descriptor: IMIDAZOLE, Proto-oncogene serine/threonine-protein kinase Pim-1
Authors:Kumar, A, Mandiyan, V, Suzuki, Y, Zhang, C, Rice, J, Tsai, J, Artis, D.R, Ibrahim, P, Bremer, R.
Deposit date:2005-02-22
Release date:2005-04-26
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structures of proto-oncogene kinase Pim1: a target of aberrant somatic hypermutations in diffuse large cell lymphoma.
J.Mol.Biol., 348, 2005
2E9W
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BU of 2e9w by Molmil
Crystal structure of the extracellular domain of Kit in complex with stem cell factor (SCF)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Kit ligand, Mast/stem cell growth factor receptor
Authors:Yuzawa, S, Opatowsky, Y, Zhang, Z, Mandiyan, V, Lax, I, Schlessinger, J.
Deposit date:2007-01-27
Release date:2007-08-07
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structural Basis for Activation of the Receptor Tyrosine Kinase KIT by Stem Cell Factor
Cell(Cambridge,Mass.), 130, 2007
2EC8
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BU of 2ec8 by Molmil
Crystal structure of the exctracellular domain of the receptor tyrosine kinase, Kit
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Mast/stem cell growth factor receptor
Authors:Yuzawa, S, Opatowsky, Y, Zhang, Z, Mandiyan, V, Lax, I, Schlessinger, J.
Deposit date:2007-02-11
Release date:2007-08-07
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural Basis for Activation of the Receptor Tyrosine Kinase KIT by Stem Cell Factor
Cell(Cambridge,Mass.), 130, 2007
1AQC
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BU of 1aqc by Molmil
X11 PTB DOMAIN-10MER PEPTIDE COMPLEX
Descriptor: PEPTIDE, X11
Authors:Lee, C.-H, Zhang, Z, Kuriyan, J.
Deposit date:1997-07-28
Release date:1997-12-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Sequence-specific recognition of the internalization motif of the Alzheimer's amyloid precursor protein by the X11 PTB domain.
EMBO J., 16, 1997
2HSP
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BU of 2hsp by Molmil
SOLUTION STRUCTURE OF THE SH3 DOMAIN OF PHOSPHOLIPASE CGAMMA
Descriptor: PHOSPHOLIPASE C-GAMMA (SH3 DOMAIN)
Authors:Kohda, D, Hatanaka, H, Odaka, M, Inagaki, F.
Deposit date:1994-06-13
Release date:1994-08-31
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Solution structure of the SH3 domain of phospholipase C-gamma.
Cell(Cambridge,Mass.), 72, 1993
1HSQ
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BU of 1hsq by Molmil
SOLUTION STRUCTURE OF THE SH3 DOMAIN OF PHOSPHOLIPASE CGAMMA
Descriptor: PHOSPHOLIPASE C-GAMMA (SH3 DOMAIN)
Authors:Kohda, D, Hatanaka, H, Odaka, M, Inagaki, F.
Deposit date:1994-06-13
Release date:1994-08-31
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Solution structure of the SH3 domain of phospholipase C-gamma.
Cell(Cambridge,Mass.), 72, 1993
1IO6
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BU of 1io6 by Molmil
GROWTH FACTOR RECEPTOR-BOUND PROTEIN 2 (GRB2) C-TERMINAL SH3 DOMAIN COMPLEXED WITH A LIGAND PEPTIDE (NMR, MINIMIZED MEAN STRUCTURE)
Descriptor: A LIGAND PEPTIDE, GROWTH FACTOR RECEPTOR-BOUND PROTEIN 2
Authors:Kawasaki, M, Ogura, K, Hatanaka, H, Inagaki, F.
Deposit date:2001-01-25
Release date:2001-02-14
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Solution Structure of the C-Terminal SH3 Domain of Grb2 Complexed with a Ligand Peptide: A Ligand Exchange Model of the SH3 Domain
To be Published
1X11
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BU of 1x11 by Molmil
X11 PTB DOMAIN
Descriptor: 13-MER PEPTIDE, X11
Authors:Lee, C.-H, Zhang, Z, Kuriyan, J.
Deposit date:1997-07-28
Release date:1998-01-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Sequence-specific recognition of the internalization motif of the Alzheimer's amyloid precursor protein by the X11 PTB domain.
EMBO J., 16, 1997
1QG1
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BU of 1qg1 by Molmil
GROWTH FACTOR RECEPTOR BINDING PROTEIN SH2 DOMAIN COMPLEXED WITH AN SHC-DERIVED PEPTIDE
Descriptor: PROTEIN (GROWTH FACTOR RECEPTOR BINDING PROTEIN), PROTEIN (SHC-DERIVED PEPTIDE)
Authors:Ogura, K.
Deposit date:1999-04-19
Release date:1999-04-27
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Solution structure of the SH2 domain of Grb2 complexed with the Shc-derived phosphotyrosine-containing peptide.
J.Mol.Biol., 289, 1999
1GCQ
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BU of 1gcq by Molmil
CRYSTAL STRUCTURE OF VAV AND GRB2 SH3 DOMAINS
Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, GROWTH FACTOR RECEPTOR-BOUND PROTEIN 2, VAV PROTO-ONCOGENE
Authors:Nishida, M, Nagata, K, Hachimori, Y, Ogura, K, Inagaki, F.
Deposit date:2000-08-08
Release date:2001-08-08
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Novel recognition mode between Vav and Grb2 SH3 domains.
EMBO J., 20, 2001
1GFD
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BU of 1gfd by Molmil
SOLUTION STRUCTURE AND LIGAND-BINDING SITE OF THE C-TERMINAL SH3 DOMAIN OF GRB2
Descriptor: GROWTH FACTOR RECEPTOR-BOUND PROTEIN 2
Authors:Kohda, D, Terasawa, H, Hatanaka, H, Inagaki, F.
Deposit date:1994-06-13
Release date:1994-08-31
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Solution structure and ligand-binding site of the carboxy-terminal SH3 domain of GRB2.
Structure, 2, 1994
1GFC
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BU of 1gfc by Molmil
SOLUTION STRUCTURE AND LIGAND-BINDING SITE OF THE C-TERMINAL SH3 DOMAIN OF GRB2
Descriptor: GROWTH FACTOR RECEPTOR-BOUND PROTEIN 2
Authors:Kohda, D, Terasawa, H, Hatanaka, H, Inagaki, F.
Deposit date:1994-06-13
Release date:1994-08-31
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Solution structure and ligand-binding site of the carboxy-terminal SH3 domain of GRB2.
Structure, 2, 1994
1GCP
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BU of 1gcp by Molmil
CRYSTAL STRUCTURE OF VAV SH3 DOMAIN
Descriptor: VAV PROTO-ONCOGENE
Authors:Nishida, M, Nagata, K, Hachimori, Y, Ogura, K, Inagaki, F.
Deposit date:2000-08-08
Release date:2001-08-08
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Novel recognition mode between Vav and Grb2 SH3 domains.
EMBO J., 20, 2001

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